CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000055016/1-1052 -----------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETA ENSRNOP00000030008/1-1036 -----------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETA ENSCPOP00000007609/1-992 ------------------------------------------------------------ ENSP00000431949/1-1047 -----------------------------MAPRLQLEKAAWRWAETVRPEEVSQEHIETA XP_004850579.1/1-1064 MRPTRRRNPFGRQRQQPRPGSGGAPGAKAMAPRLQLEKAAWRWAETVRPEEVSQEHIETA ENSMUSP00000055016/1-1052 YRIWLEPCIRGVCRRNCRGNPNCLVGIGEHIWLGEIDENSFHSIDDPNCERRKKNSFVGL ENSRNOP00000030008/1-1036 YRIWLEPCIRGVCRRNCRGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGL ENSCPOP00000007609/1-992 -------------RRNCKGNPNCLVGIGEHIWLGEIDENTFHNIDDPNCERRKKNSFVGL ENSP00000431949/1-1047 YRIWLEPCIRGVCRRNCKGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGL XP_004850579.1/1-1064 YRIWLEPCIRGVCRRNCKGNPNCLVGIGEHIWLGEIDENSFHNIDDPNCERRKKNSFVGL ****:*********************:**.***************** ENSMUSP00000055016/1-1052 TNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGDGIHGGKDYEPQTICEHLQYL ENSRNOP00000030008/1-1036 TNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYTKGDGIRGGKDYEPQTICEHLQYL ENSCPOP00000007609/1-992 TNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDHMRGDGVHEEKDYEPQTICEHLQYL ENSP00000431949/1-1047 TNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYL XP_004850579.1/1-1064 TNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMMEDGVHEEKDYEPQTICEHLQYL ***********************************: **:: *************** ENSMUSP00000055016/1-1052 FALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNVVQQ ENSRNOP00000030008/1-1036 FALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNVVQQ ENSCPOP00000007609/1-992 FALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPHVKNIVQQ ENSP00000431949/1-1047 FALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQQ XP_004850579.1/1-1064 FALLQNSNRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVQNIVQQ ****************************************************.*:*:*** ENSMUSP00000055016/1-1052 QFCGEYAYVTVCNQCGRESKLVSKFYELELNIQGHKQLTDCISEFLKEERLEGDNRYFCE ENSRNOP00000030008/1-1036 QFCGEYAYVTVCSQCGRESKLVSKFYELELNIQGHKQLTDCISEFLKEERLEGDNRYFCE ENSCPOP00000007609/1-992 QFCGEYAYLTACNQCGRQSRLIAKFYELELSIQGHKQLTDCISEFLKEEKLEGDNRYYCE ENSP00000431949/1-1047 QFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCE XP_004850579.1/1-1064 QFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISEFLKEEKLEGDNRYFCE ********:*.*.****:*:*::*******.******************:*******:** ENSMUSP00000055016/1-1052 NCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESLDMEPYVEHKG ENSRNOP00000030008/1-1036 NCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNAYIGFSESLDMEPYVEHKG ENSCPOP00000007609/1-992 NCQSKQNATRTMQLVTLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYMEQKG ENSP00000431949/1-1047 NCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKG XP_004850579.1/1-1064 NCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYVEHKD **********.::*::*************************:****** ******:*:*. ENSMUSP00000055016/1-1052 GSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDL- ENSRNOP00000030008/1-1036 GSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGDWYKFNDEDIEKMEGKKLQLGIEEDLA ENSCPOP00000007609/1-992 GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLA ENSP00000431949/1-1047 GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDL- XP_004850579.1/1-1064 GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDL- **:******************************:************************* ENSMUSP00000055016/1-1052 EPSKSQTRKPKCGKGTHCSRNAYMLVYRLQAQEKNHTMVQVPAFLQELVDRDNSKFEEWC ENSRNOP00000030008/1-1036 EPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKNHTMVQVPAFLQELVDRDNSKFEEWC ENSCPOP00000007609/1-992 EPSKSQTRRPKCGKGTHCSRNAYMLVYRLQSQEKSNTTVEVPAFLQELVDRDNSKFEEWC ENSP00000431949/1-1047 EPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFLQELVDRDNSKFEEWC XP_004850579.1/1-1064 EPSKSQTRRPKCGKGTHCSRNAYMLVYRLQSQEKPNSAVEVPAFLQELVERDNSKFEEWC ********:*********************:*** :: *:*********:********** ENSMUSP00000055016/1-1052 VEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNNA ENSRNOP00000030008/1-1036 VEMAEMRRQSVDKGRAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNNA ENSCPOP00000007609/1-992 VEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHA ENSP00000431949/1-1047 IEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHA XP_004850579.1/1-1064 VEMAEMRKQSVDKGKAKHEEVKELYQRLPAGAEPYEFVSLEWLQKWLDESTPTKPIDNHA :******:******:*******************************************:* ENSMUSP00000055016/1-1052 CLCSHDKLHPDKISIMKRISEYAANIFYSRYGGGPRLTVKALCKDCVVERCRVLRLKNQL ENSRNOP00000030008/1-1036 CLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKDCVVERCRILRLKNQL ENSCPOP00000007609/1-992 CLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRVLRLKNQL ENSP00000431949/1-1047 CLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRILRLKNQL XP_004850579.1/1-1064 CLCSHDKLHPDKISIMKRISEYAADIFYSRYGGGPRLTVKALCKECVVERCRVLRLKNQL ************************:*******************:*******:******* ENSMUSP00000055016/1-1052 NEDYKAVNNLLKSTMKG-DGFWVGKSSLRSWRQLALEQLDEQDGEAEQSNGKINGSTFNK ENSRNOP00000030008/1-1036 NEDYKTVNNLLKATMKGSDGFWVGKSSLRSWRQLALEQLDEQDGEAEQSNGKINGSPFSK ENSCPOP00000007609/1-992 NEDYKMVNNLLKATGKGNDGFWVGKSSLRSWRQLALEQLDEQDGDADQSNGKMNGSTFNK ENSP00000431949/1-1047 NEDYKTVNNLLKAAVKGSDGFWVGKSSLRSWRQLALEQLDEQDGDAEQSNGKMNGSTLNK XP_004850579.1/1-1064 NEDYKMVNNLLKATGKGDDGFWVGKSSLRSWRQLALEQLDEQDGDADQSNGKMNGNTFSK ***** ******:: ** **************************:*:*****:**..:.* ENSMUSP00000055016/1-1052 DESKEEKKEEEEELNFNEDILCPH-------------GELSISENERRLVSQEAWSKLQQ ENSRNOP00000030008/1-1036 DESKEEKKEEEEELNFNEDILCPH-------------GELSISENERRLVSQEAWSKLQQ ENSCPOP00000007609/1-992 DEPKEERKEEEEELNFNEDILCPH-------------GELCISENERRLVSKEAWSKLQQ ENSP00000431949/1-1047 DESKEERK-EEEELNFNEDILCPHAVFFFSKYIFLNSGELCISENERRLVSKEAWSKLQQ XP_004850579.1/1-1064 DESKEERKEEEEELNFNEDILCPH-------------GELCISENERRLVSKEAWSKLQQ **.***:* *************** ***.**********:******** ENSMUSP00000055016/1-1052 YFPKAPEFPSYRECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPE ENSRNOP00000030008/1-1036 YFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPE ENSCPOP00000007609/1-992 YFPKAPEFPSYRECCSQCKILEREGEENEALHKMIANEQKSSLTNLFQDKNRPCLSNWPE ENSP00000431949/1-1047 YFPKAPEFPSYKECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPE XP_004850579.1/1-1064 YFPKAPEFPSYRECCSQCKILEREGEENEALHKMIANEQKTSLPNLFQDKNRPCLSNWPE ***********:****************************:**.**************** ENSMUSP00000055016/1-1052 DTDALYIVSHFFLDEWRKFVRKPARSAPVSSIGNAALLCPHGGLMFTFPSLTKEDSKLCQ ENSRNOP00000030008/1-1036 DTDALYIVSHFFLDEWRKFVRKPARSTPVSSVGNAALLCPHGGLMFTFPSLTKEDSKL-- ENSCPOP00000007609/1-992 DTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKL-- ENSP00000431949/1-1047 DTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKL-- XP_004850579.1/1-1064 DTDVLYIVSQFFVEEWRKFVRKPTRCSPVSSVGNSALLCPHGGLMFTFASMTKEDSKL-- ***.*****:**::*********:*.:****:**:*************.*:******* ENSMUSP00000055016/1-1052 PLERREGGWPTAAHNNIALIWPSEWQMIQKLFVVDKVIKITRIEVGDVNPSQTQYISEPS ENSRNOP00000030008/1-1036 ----------------IALIWPSEWQMIQKLFVVDKVIKITRIEVGDVNPSQTQYISEPN ENSCPOP00000007609/1-992 ----------------IALIWPSEWQMIQKLFVVDHIIKITRIEVGDVNASETQYILEPK ENSP00000431949/1-1047 ----------------IALIWPSEWQMIQKLFVVDHVIKITRIEVGDVNPSETQYISEPK XP_004850579.1/1-1064 ----------------IALIWPSEWQMIQKLFVVDHIIKITRIEVGDVNPSETQYISEPK *******************::************.*:**** **. ENSMUSP00000055016/1-1052 LCPDCREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKP ENSRNOP00000030008/1-1036 LCPDCREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKP ENSCPOP00000007609/1-992 LCPDCREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKP ENSP00000431949/1-1047 LCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKP XP_004850579.1/1-1064 LCPECREGLLCQQQRDLREYTQATIYVHKVVDNKKVMKDSAPELNVSSSETEEDKEEAKP ***:******************************************************** ENSMUSP00000055016/1-1052 DGEKDPDFNQSNGSTKRQKTSQQGYVAYQKQVIRRSTRHRKVRGEKALLVSANQTLKELK ENSRNOP00000030008/1-1036 DGEKDPDFNQSNGGTKRQKTSQQGYVAYQKQVIRRSTRHRKVRGEKALLVSANQTLKELK ENSCPOP00000007609/1-992 DGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELK ENSP00000431949/1-1047 DGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELK XP_004850579.1/1-1064 DGEKDPDFNQSNGGTKRQKISHQNYIAYQKQVIRRSMRHRKVRGEKALLVSANQTLKELK *************.***** *:*.*:********** *********************** ENSMUSP00000055016/1-1052 IQIMHAFSVAPFDQNLSIDGKILNDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQ ENSRNOP00000030008/1-1036 IQIMHAFSVAPFDQNLSIDGKILNDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQ ENSCPOP00000007609/1-992 IQIMHAFSVAPFDQNLSIDGKILSDDCATLGNLGVIPESVILLKADEPIADYAAMDDVMQ ENSP00000431949/1-1047 IQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQ XP_004850579.1/1-1064 IQIMHAFSVAPFDQNLSIDGKILSDDCATLGTLGVIPESVILLKADEPIADYAAMDDVMQ ***********************.*******.**************************** ENSMUSP00000055016/1-1052 VCMPEEGFKGTGLLGH ENSRNOP00000030008/1-1036 VCMPEEGFKGTGLLGH ENSCPOP00000007609/1-992 VCMPEEGFKGTGLLGH ENSP00000431949/1-1047 VCMPEEGFKGTGLLGH XP_004850579.1/1-1064 VCMPEEGFKGTGLLGH ****************