CLUSTAL W(1.81) multiple sequence alignment ENSP00000440679/1-968 MVLGCELSGSTRVVVGVEALLTGASSPLPGVGPANKHKPWIEAEYQGIVMENDNTVLLNP XP_004869542.1/1-959 -----------MTLLLLPLMLASLFPPSCG-NKANKHKPWIEAEYQGIVMENDNTVLLNP ENSCPOP00000007310/1-959 -----------MSLLLLSLLLASLLPPSYG-NKANKHKPWIEAEYQGIVMENDNTVLLNP ENSMUSP00000008297/1-956 -----------MTLLLVSLLLASLLQISSG-NKANKHKPWIEAEYQGIVMENDNTVLLNP ENSRNOP00000015570/1-957 -----------MTLLLVSLLLASLLQISSG-NKANKHKPWIEAEYQGIVMENDNTVLLNP :: : :*:. * . *************************** ENSP00000440679/1-968 PLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFT XP_004869542.1/1-959 PLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHSFT ENSCPOP00000007310/1-959 PLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFT ENSMUSP00000008297/1-956 PLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFT ENSRNOP00000015570/1-957 PLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFT *********************************************************:** ENSP00000440679/1-968 IQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEA XP_004869542.1/1-959 IQAYDCGEGPDGVNTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEA ENSCPOP00000007310/1-959 IQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEA ENSMUSP00000008297/1-956 IQAYDCGEGPDGTNTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEA ENSRNOP00000015570/1-957 IQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEA ************.*********************************************** ENSP00000440679/1-968 IDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRA XP_004869542.1/1-959 IDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRA ENSCPOP00000007310/1-959 IDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRA ENSMUSP00000008297/1-956 IDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRA ENSRNOP00000015570/1-957 IDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRA *******************************************:**************** ENSP00000440679/1-968 ADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQT XP_004869542.1/1-959 ADDAEVQIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQT ENSCPOP00000007310/1-959 ADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQT ENSMUSP00000008297/1-956 ADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQT ENSRNOP00000015570/1-957 ADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQT ******:***************************************************** ENSP00000440679/1-968 SHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNG XP_004869542.1/1-959 SHVAKGCDRDNYSERALRKLCGASPGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNG ENSCPOP00000007310/1-959 SHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPSANWTAGLSVHYSQDSSLIYWFNG ENSMUSP00000008297/1-956 SHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNG ENSRNOP00000015570/1-957 SHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNG ***********************:.***********.*********************** ENSP00000440679/1-968 TQAVQVPLGGPSGLGSGPQDSLSDHFTLSFWMKHGVTPNK--GKKEEETIVCNTVQNEDG XP_004869542.1/1-959 TQAVQVPPGGTAGLGTGPQDSLSDHFTLSFWMKHGATPNKKEGKKEEETIVCNTVQNEDG ENSCPOP00000007310/1-959 TQAVQVPLGSTAGLGSGPQESLSDHFTLSFWMKHGATPSKKESKKEEETIVCNTVQNEDG ENSMUSP00000008297/1-956 TQAVQVPLGGPAGLGSGPQDGFSDHFTLSFWMKHSVTPSK--GKKEEETIVCNTVQNEDG ENSRNOP00000015570/1-957 TQAVQVPLGGPAGLGSGPQDGLSDHFTLSFWMKHSVTPSK--GKKEEETIVCNTIQNEDG ******* *..:***:***:.:************..**.* .***********:***** ENSP00000440679/1-968 FSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGI XP_004869542.1/1-959 FSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYADGI ENSCPOP00000007310/1-959 FSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYADGI ENSMUSP00000008297/1-956 YSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGI ENSRNOP00000015570/1-957 YSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGI :*******************************************************:*** ENSP00000440679/1-968 SFDPALIHDNGLIHPPRREPALMIGACWTEEKNKEKEK-GDNSTDTTQGDPLSIHHYFHG XP_004869542.1/1-959 SFDPALIHDNGLIHPPRREPVLMIGACWTEEKNKEKEKGGDNSTDTTRGDPLPIHHYFHG ENSCPOP00000007310/1-959 SFDPALIHDNGLIHPPRREPALMIGACWTEEKNKEKEKGGDNSTDPAQGDPLPIHHYFHG ENSMUSP00000008297/1-956 SFDPALIHDNGLIHPPRREPALMIGACWTEEKNKEK-KGGENSTDTASGDPLLIHHYFHG ENSRNOP00000015570/1-957 SFDPALIHDNGLIHPPRREPALMIGACWSEEKNKEKEKGGENSTDTTSGDPLPIHHYFHG ********************.*******:******* * *:****.: **** ******* ENSP00000440679/1-968 YLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVET XP_004869542.1/1-959 YLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVET ENSCPOP00000007310/1-959 YLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVET ENSMUSP00000008297/1-956 YLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVET ENSRNOP00000015570/1-957 YLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVET ************************************************************ ENSP00000440679/1-968 FNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILL XP_004869542.1/1-959 FNHALQHVAYMNSLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILL ENSCPOP00000007310/1-959 FNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILL ENSMUSP00000008297/1-956 FNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILL ENSRNOP00000015570/1-957 FNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILL ************:*********************************************** ENSP00000440679/1-968 SGTAHFARPAVDFEGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNL XP_004869542.1/1-959 SGTAHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNL ENSCPOP00000007310/1-959 SGTAHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNL ENSMUSP00000008297/1-956 SGTAHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNL ENSRNOP00000015570/1-957 SGTAHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNL ***************.:********************* ********************* ENSP00000440679/1-968 DGCEISLVGDDLDPERESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARY XP_004869542.1/1-959 DGCEVSLVGDDLDPEKESLLLDMTSVQQRGLELTNTSAYLTIAGVESITVYEEILRQAHY ENSCPOP00000007310/1-959 DGCEISLVGDDLDPERESLLLDMASLQQRGLELTNTSAYLTIAGVESITVYEEILRQAHY ENSMUSP00000008297/1-956 DGCEISLVGDDLDPERESLLLDMASLQQRGLELTNTSAYLTIAGVETITVYEEILRQARY ENSRNOP00000015570/1-957 DGCEISLVGDDLDPERESLLLDMASLQQRGLELTNTSAYLTIAGVETITVYEEILRQVHY ****:**********:****** :*:********************:**********.:* ENSP00000440679/1-968 RLRHGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQ XP_004869542.1/1-959 QLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSVNRVAHPSHVLSSQQFLHRGHQ ENSCPOP00000007310/1-959 RLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQ ENSMUSP00000008297/1-956 QLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQ ENSRNOP00000015570/1-957 QLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQ :********:****************************:********************* ENSP00000440679/1-968 PPPEMAGHSLASSHRNSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPG XP_004869542.1/1-959 PPPEMAGHSLASSHRNSMVPSAATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGLSGPPG ENSCPOP00000007310/1-959 PPPEMAGHSLASSHRNSMVPSAATLIIVVCVGFLVLMVILGLVRIHSLHRRVAGTSGPPG ENSMUSP00000008297/1-956 PPPEMAGHSLASSHRNSMVPSAATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSG ENSRNOP00000015570/1-957 PPPEMAGHSLASSHRNSMVPSAATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSG ******************:*******************:*************:* .**.* ENSP00000440679/1-968 ASSDPKDPDLFWDDSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDE XP_004869542.1/1-959 ASSDPKDPDLFWDDSALTIIVNPMESYQSRQACVVGAAGSQQEDEDSSDSEAANSPSSDE ENSCPOP00000007310/1-959 ASSDPKDPDLFWDDSALTIIVNPMESYQNRQACVTGAAGGQQEDEDSSDSEAADSPSSDE ENSMUSP00000008297/1-956 ASTDPKDPDLFWDDSALTIIVNPMESYQNQQTCVAGVAGGQQEEEDSSDSEAADSPSSDE ENSRNOP00000015570/1-957 ASADPKDPDLFWDDSALTIIVNPMESYQNQQTGVAGVAGGQQEEEDSSDSEAADSPSSDE **:*************************.:*: *.*..*.***:*******.*:****** ENSP00000440679/1-968 RRIIETPPHRY XP_004869542.1/1-959 RRIIESPAQRY ENSCPOP00000007310/1-959 RRIIESPPHRY ENSMUSP00000008297/1-956 RRIIESPPHRY ENSRNOP00000015570/1-957 RRIIESPPHRY *****:*.:**