CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000123787/1-1002 MEEIRSVVTTDSQGSKTLS-SRGLEGQNGRSLDTESQDSVKSYTFF-RRSRPGDLGEDEE ENSRNOP00000067107/1-1001 MEEVRSIVTLDSQGSKTFS-SRGLEGQSGRSPDTESQHSSKSYTFFSRRDHPGDL-REDE ENSP00000385887/1-1030 MEGAHASLSLEDEVSGAGSRQRPLEGKGGETPAAEEPGSLKNYAVFATRDVSAAPEKEEE ENSCPOP00000007017/1-902 ------------------------------------------------------------ XP_004868591.1/1-931 MERDRPFVVLDYGSRG------PLEEQNAQPPATEHPRRLDS-GLLTARDSSVSPAEEDE ENSMUSP00000123787/1-1002 ESEGTVGEQDLKGTYKQLVQGVQEWQDGCVYKGEFGLNMKLGYGEFSWPTGEAYHGQFYR ENSRNOP00000067107/1-1001 ESEGTTGEEELKGTYMHLVQGVQEWQDGCVYKGEFGLNMKLGHGEFSWPTGEIYRGQFYR ENSP00000385887/1-1030 EAEGPLRAQDLRESYIQLVQGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYR ENSCPOP00000007017/1-902 -----------------------------VYQGEFGLGVKFGYGEFSWPTGEAYCGQFCH XP_004868591.1/1-931 ESEGPLSGRGLKEASIQLVHGVQTWRDGCVYRGEFGLNVKLGYGEFSWPTGETYRGQFYR :*:*****.:*:*:*:******* * *** : ENSMUSP00000123787/1-1002 DHFHGLGTYTWPDGSSFTGTFYLSQREGYGTMHTKTMLFQGLYKEDQRFGPGIETYPDGS ENSRNOP00000067107/1-1001 DHYHGMGTYSWPDGSSFTGTFYLSQREGYGTMYTKAKLFQGLYKEDQRFGPGIETYPDGS ENSP00000385887/1-1030 DHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKTRLFQGLYKADQRFGPGVETYPDGS ENSCPOP00000007017/1-902 DHCHGLGTYVWPDGCSFTGTFYLSQREGYGSMNLKKRLFQGLYKADVRFGPGVETYPDGS XP_004868591.1/1-931 DHCHGLGTYVWPDGSSFTGTFYLSHREGYGSMNLKTRLFQGLYKADIRFGPGIETYPDGS ** **:*** ****.*********:*****:* * ******* * *****:******* ENSMUSP00000123787/1-1002 QDVGLWFREYLLKLCTRVPSGFSLVNYPEFLAFLTKSRRRLDLSD-EKVELGLSEEQDPF ENSRNOP00000067107/1-1001 QDVGIWFREYLLKLCTRVPSSFSLINYPEFSAFLTNTRKRISLSDEEKVEVSLSEEQDPF ENSP00000385887/1-1030 QDVGLWFREQLIKLCTQIPSGFSLLRYPEFSSFITHSPARISLSEEEKTEWGLQEGQDPF ENSCPOP00000007017/1-902 QDVGLWFREHLIKLATKTPGSFSVLSYPEFSAFLSCSRDRISLVEPESTAKGPSEAQDPF XP_004868591.1/1-931 QDVGLWFRTHLIKLVTKTASSFSVLSYPEFSAFLTCSRERISLSDEEGVEWGPLEGQDPF ****:*** *:** *: ...**:: **** :*:: : *:.* : * . . * **** ENSMUSP00000123787/1-1002 FYDYKQYLLNDELKLPPEMHVYSTDNSHLPMTDSLRQELDDHIFMNEIPPFIEDEEPWLI ENSRNOP00000067107/1-1001 YYDYKQYLLNDDLKLPPEIHVYSTNNSHLPMTNALRKELDNQIFMNEIPPFIEDEEPWLI ENSP00000385887/1-1030 FYDYKRFLLNDNLTLPPEMYVYSTNSDHLPMTSSFRKELDARIFLNEIPPFVEDGEPWFI ENSCPOP00000007017/1-902 FYEYKRFLLNENLTLPPDIQLYSTDYCHLPMTGSFRRELDAQIFANEIPPFVDDGEPWFI XP_004868591.1/1-931 FYEYKRFLLSDSLTLPPEMQAYSTDHCHLPMTSSFRRELDARIFLDDIPPFVDDGEPWFT :*:**::**.:.*.***:: ***: *****.::*:*** :** ::****::* ***: ENSMUSP00000123787/1-1002 TNETPLLVKIQKQTYKFRNKDAHTSWNIPAILEGNRSRFGPSGPKEQISKKMIMKAEEGD ENSRNOP00000067107/1-1001 TNETPLLVKIQKQTYKFRNKDAHANWNIAAILEGNRSKFGPSGPKEQISKKMIMKAEEGD ENSP00000385887/1-1030 INETPLLVKIQKQTYKFRNKPAHTSWNMGAILEGKRSGFAPCGPKEQLSMEMILKAEEGN ENSCPOP00000007017/1-902 TNETPLLVKIQKQAYKFRNKKAHTSWNMGAILEGNRSGFACSGPKEQYSQEMILKAEEGD XP_004868591.1/1-931 ANKTPLLVKIQKQAYKFRNKKAHTSWNMGAILEGDRGGFASIGPKEQFSQELILKAEEGD *:**********:****** **:.**: *****.*. *. ***** * ::*:*****: ENSMUSP00000123787/1-1002 YNWIFGILRDNLACADVADSKGYTVLAAAAMHSHLDIVNLLLDFGADVNKRSDEGITPLS ENSRNOP00000067107/1-1001 YNWIFGILRDNLACADVADSKGYTVLAAAAIHSHINIVNLLLDYGADVNKRSDEGITPLS ENSP00000385887/1-1030 HEWICRILKDNFASADVADAKGYTVLAAAATHCHNDIVNLLLDCGADVNKCSDEGLTALS ENSCPOP00000007017/1-902 YGWIYGVLKDNLACADVADAKGYTALAAAAVHCHNDIVSLLLDHGANVNKFTDEGLTALN XP_004868591.1/1-931 HDRVYGILKDNLAYADVTDAKGYTVLAAAAVHCHNDIVNLLLDHGANVNKFTDEGLTPLN : : :*:**:* ***:*:****.***** *.* :**.**** **:*** :***:*.*. ENSMUSP00000123787/1-1002 MCFLQYYPCKSFHPNIAERTLLQ--ESPKSLVTPKISFLLADANIDYL-YDVGMPIAGGD ENSRNOP00000067107/1-1001 MCFLQYYPSKSFHPNIAERTLLQ--ESPKPLVTPKISFLFADPNTDSS-YDVGAHILGGE ENSP00000385887/1-1030 MCFLLHYPAQSFKPNVAERTIPEPQEPPKFPVVPILSSSFMDTNLESLYYEVNVPSQGSY ENSCPOP00000007017/1-902 MCFILYYPSESFKLNVAERTMTQQPENLKPFLIPKPSPLVVETNVEST-YEVVELGPDSR XP_004868591.1/1-931 MCFLLYYPSESFKPNVAERTVPQ--ENPKPLFTPKPSPSCVETHVEST-YEVVTSSPGSG ***: :**.:**: *:****: : * * . * * :.: : *:* .. ENSMUSP00000123787/1-1002 ELK----------TSSLDDSLASMQTPESSNMLH------KEEVSPVKTVSTDVEKESEG ENSRNOP00000067107/1-1001 ELK----------TSLLQESLASMPPPESNNVLQ------KRDVSPVKTVSTEVEKETED ENSP00000385887/1-1030 ELRPPPAPLLLPRVSGSHEGGHFQDTGQCGGSIDHRSSSLKGDSPLVKGSLGHVESGLED ENSCPOP00000007017/1-902 EQKLLSH------TSGSQEDEPALGTLQSS----------ESSFPSGQGIVSDRERRLEA XP_004868591.1/1-931 EQKPPSC------TSGSQEDGSAPGTQQSLES--------ESSFPSGQGTVSDRERGLEG * : .* .:. . :. : . . : . * * ENSMUSP00000123787/1-1002 AAENVDASTLYSVDTNFESTKCLRNYTINVSRDIMEKSAQAYSSLPQHPCFP-----YKG ENSRNOP00000067107/1-1001 VAENVDASTLYSADTNFESTICLRNYSINVSRDILEKSAQAYSSLVQHSCFP-----YKG ENSP00000385887/1-1030 VLGNTDRGSLCSAETKFESNVCVCDFSIELSQAMLERSAQSHSLLKMASPSPCTSSFDKG ENSCPOP00000007017/1-902 VPEGLDTSPTCS-EMRFDSNVCVHNYSIQLTRGLLEKSAQTYSTL-QGPTTP-----DQG XP_004868591.1/1-931 LPGGLDVSPPCS-EAHFESDLCVRSYSIQLSRDMLEKSAQAYSML-QVPGAP-----DKG . * .. * : .*:* *: .::*:::: ::*:***::* * . * :* ENSMUSP00000123787/1-1002 TVRKMAQSMVERRNRWMTITLLLRRGADPNLCQVPMQALFLAVKAGDVEGVRLLLMSGAQ ENSRNOP00000067107/1-1001 TVRKLAQTMAERRNRWMTIMLLLRRGADPNLCQVPMQALFLAVKAGDVEGVRLLLMNGAQ ENSP00000385887/1-1030 TMRRMALSMIERRKRWRTIKLLLRRGADPNLCCVPMQVLFLAVKAGDVDGVRLLLEHGAR ENSCPOP00000007017/1-902 TVRRMAWSMVEHRCRWLTIKLLLHRGADPNLCQVPMRALFFAVKAGDVDGVQLLLERGAR XP_004868591.1/1-931 TVRSMAWSMVKRRCRWLTIKLLLHRGADPNLCCVPMRALFFAVKAGDVDGVRVLLESGAR *:* :* :* ::* ** ** ***:******** ***:.**:*******:**::** **: ENSMUSP00000123787/1-1002 TDIQFPPQLQSLTPLHIAVSLPGEEGVKITELLLHVITNVDAKAADEDYVYKGGKADLLP ENSRNOP00000067107/1-1001 TDIQYPPQLQSLTPLHIAASLPGEEGVKITELLLHAVTNVDAKAADQDYPYKGGKGD-LP ENSP00000385887/1-1030 TDICFPPQLSTLTPLHIAAALPGEEGVQIVELLLHAITDVDAKASDEDDTYKPGKLDLLP ENSCPOP00000007017/1-902 TDIRYPPHLGALTPLHIAAALPGEEGIKITELLLHAITDVDAKAADQDEVYKLGKMELLP XP_004868591.1/1-931 TDIRYPPQLGALTPLHIAAALPGEEGVRITELLLHAITDVDAKAADQDDVYKLGKLDLLP *** :**:* :*******.:******::*.*****.:*:*****:*:* ** ** : ** ENSMUSP00000123787/1-1002 SSLKLNNEPGPPKSFYSTHTFIPEEGGRTALHVACEREDNKKCARDIVRLLLSHRANPNV ENSRNOP00000067107/1-1001 SSLKLNNEPGPPKSYYSPYTRIPEEGGRTALHVACEREDNKKCARDIVRLLLSHRANPNT ENSP00000385887/1-1030 SSLKLSNEPGPPQAYYSTDTALPEEGGRTALHMACEREDDNKCARDIVRLLLSHGANPNL ENSCPOP00000007017/1-902 SSLKLSNEPGPPSIYYTASTQVVEEGGRTALHVACEREDNNKCARDVVQLLLSHGANPNL XP_004868591.1/1-931 SSLKLNNEPGPPSTYYTASTCVAEEGGRTALHVACEREDSHQCARDVVRLLLSHGASPNL *****.******. :*:. * : *********:******.::****:*:***** *.** ENSMUSP00000123787/1-1002 LWSGHSPLSLAIASGNDLVVKELLSQGADPNLPLTKGLGTALCVVCDLVYEQQRSVENKI ENSRNOP00000067107/1-1001 LWSGHSPLSLSIASGNDLVVKELLAQGADPNLPLTKGLGTALCVVCDLFYEQQRSTDNKI ENSP00000385887/1-1030 LWSGHSPLSLSIASGNELVVKELLTQGADPNLPLTKGLGSALCVACDLTYEHQRNMDSKL ENSCPOP00000007017/1-902 LWSGHSPLSLSIASGNDLIVKELLSCGADPNLPLTRGLGTALCVVCDLAYEHQRSTDNKI XP_004868591.1/1-931 LWSGHSPLSLSIASGNDLVVEELLSCGADPNLPLTRGLGSALCVVCDLAYEQQRSTDNKI **********:*****:*:*:***: *********:***:****.*** **:**. :.*: ENSMUSP00000123787/1-1002 ALIDRLISYGADVLNPVTLVQGDRTAVGTAVDYGYFKFFQDRKIAHCPFHALMPAEREVF ENSRNOP00000067107/1-1001 ALIDRLISYGADVLKPVTIVQGERTAVGTAVDYGYFKFYQDRKIAHCPFHALMPAEREIF ENSP00000385887/1-1030 ALIDRLISHGADILKPVMLRQGEKEAVGTAVDYGYFRFFQDRRIARCPFHTLMPAERETF ENSCPOP00000007017/1-902 TLIDRLLDHGADILKPVMLTQGDKTAVGTAVDYGYFKFFQDRKIAHFPFHALLPSERETL XP_004868591.1/1-931 TLVDRLLNHGADILKPVTLTQGDRVAVGTVVDYGYFKFFQDRKIAHCPFHVLLPAERETF :*:***:.:***:*:** : **:: ****.******:*:***:**: ***.*:*:*** : ENSMUSP00000123787/1-1002 MARKRLLEYLGLQLRLAVLSKESRLDTKALYLSKRAELAPCHRLKKKGSSSVRTQSSEKQ ENSRNOP00000067107/1-1001 IARKRLLEYLGLQLRLAVLNKESRLDVKALYLSKRAELAPCHRMKKRSSSPAKSPSMEKQ ENSP00000385887/1-1030 LARKRLLEYMGLQLRQAVFAKESQWDPTWLYLCKRAELIPSHRMKKKGPSLPRGLDVKEQ ENSCPOP00000007017/1-902 LARKRLLEHMGLQLRRAVLAKEQEWDRKVMCQSRKAELYPGQRMKKRSSSLAKALDTEGQ XP_004868591.1/1-931 LARKRLLEYMGSQLRLAVLAREREWDRKAMSRSRKAELCPGHTMKKRSLGLAKALAAEGQ :*******::* *** **: :* . * . : .::*** * : :**:. . : : * ENSMUSP00000123787/1-1002 SI-PFYKFCYQCGRSIGVRLSPCPRCYGILTCSKYCKTKAWIEFHKKDCNDIMAMIPHLE ENSRNOP00000067107/1-1001 TL-PFYKFCYQCGRSIGVRLSPCPRCYGILTCSKYCKTKAWIEFHKKDCNDIMAMISHLD ENSP00000385887/1-1030 GQIPFFKFCYQCGRSIGVRLLPCPRCYGILTCSKYCKTKAWTEFHKKDCGDLVAIVTQLE ENSCPOP00000007017/1-902 EMAPFFKFCYQCGRSIGVRLTPCARCYGILTCSKNCKSRAWTEFHKKDCNEMMAM----- XP_004868591.1/1-931 EL---------------------------------------------------------- ENSMUSP00000123787/1-1002 GSAWRVAESP ENSRNOP00000067107/1-1001 GSPWRVAES- ENSP00000385887/1-1030 QVSRRREEFQ ENSCPOP00000007017/1-902 ---------- XP_004868591.1/1-931 ----------