CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000005218/1-780 MDKFWWHTAWG-LCLLQLSLAHPHQQIDLNVTCRYAGVFHVEKNGRYSISRTEAADLCQA ENSRNOP00000009000/1-779 MDKVWWHTAWGLLCLLQLSLA--QQQIDLNITCRYAGVFHVEKNGRYSISRTEAADLCEA ENSP00000398632/1-742 MDKFWWHAAWG-LCLVPLSLA----QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKA ENSCPOP00000007016/1-792 -GKFQWAGQRG-RPVLALGLSL-RQPIDLNITCRYAGVFHVEKNGRYSISRTEAADLCEA XP_004852098.1/1-697 MDKFWWRAAWG-LCLLQLSLA--QVHIDLNITCRYAGVFHVEKNGRYSISRTEAADLCKA .*. * * :: *.*: ****:***:***********************:* ENSMUSP00000005218/1-780 FNSTLPTMDQMKLALSKGFETCRYGFIEGNVVIPRIHPNAICAANHTGVYILVTSNTSHY ENSRNOP00000009000/1-779 FNTTLPTMAQMELALSKGFETCRYGFIEGHVVIPRIHPNAICAANNTGVYILLASNTSHY ENSP00000398632/1-742 FNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYIL-TSNTSQY ENSCPOP00000007016/1-792 FNTTLPTMAQMERALHHGFETCRYGFIEGHVVIPRITPNAICAANNTGVYIL-TSNNSHY XP_004852098.1/1-697 FNTTLPTMAQMELALSKGFETCRYGFIEGHVVIPRINPNAICAANNTGVYIL-PSNTSHY **:***** **: ** ************:****** **:*****:****** .**.*:* ENSMUSP00000005218/1-780 DTYCFNASAPP-EEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASN- ENSRNOP00000009000/1-779 DTYCFNASAPL-EEDCTSVTDLPNSFDGPVTITIVNRDGTRYSKKGEYRTHQEDIDASN- ENSP00000398632/1-742 DTYCFNASAPP-EEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSN- ENSCPOP00000007016/1-792 DTYCFNASAPLDKEDCASVTDLPNSFAGQVTITIVNRDGTRYSKKGEYRTHQEDIYPINS XP_004852098.1/1-697 DTYCFNASAPLDEEDCTSVTDLPNSFEGQVTISIVNRDGTRYTKKGEYRTNPEDINPIN- ********** :***:*******:* * :**:********* :******: *** . * ENSMUSP00000005218/1-780 -----IIDDDVSSGSTIEK-STPESY-ILHTYLPTEQPTGDQDDSFFIRSTLATIASTVH ENSRNOP00000009000/1-779 -----IIDEDVSSGSTIEK-STPEGY-ILHTDLPTSQPTGDRDDAFFIGSTLATIASTVY ENSP00000398632/1-742 -----PTDDDVSSGSSSERSSTSGGY-IFYTF-STVHPIPDEDSPWITDST--------- ENSCPOP00000007016/1-792 TNPISPMDEDVSSGSPSER-STYGGYSIFHTLLPTAHPTSDQMNTEVYGSTRDTLALTLT XP_004852098.1/1-697 -----PLDEDVSSGSSSER-STLGGYSIFHTHLPTTHPTSDLANTGVYGST--------- *:******. *: ** .* *::* .* :* * .. . ** ENSMUSP00000005218/1-780 SKSHAAAQKQNNWIWSWFGNSQSTTQ------TQEPTTSATTALMTTPETPPKRQEAQNW ENSRNOP00000009000/1-779 SKSHATAQKQNNWIWSWFGNSQSTTQ------TQEPTTTATTALMTTPETPPKRQEAQNW ENSP00000398632/1-742 --------------------------------DRIPATTLMSTSATATETATKRQETWDW ENSCPOP00000007016/1-792 SNIHAAVKEQSDWIWSWFGNTNLQTQDLTTATTVMVTTTLMSTNGATLETATKRQETQEC XP_004852098.1/1-697 ------------------------------------------------------------ ENSMUSP00000005218/1-780 FSWLFQPSESKSHLHTTTKMPGTESNTNPTGWEPNEENEDETDKYPSFSGSGIDDDEDFI ENSRNOP00000009000/1-779 FSWFFQPSESKSHLHTTTKMPGTESNTNPTGWKPNEENEDETDKYPNFSGSGIDDDEDFI ENSP00000398632/1-742 FSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFI ENSCPOP00000007016/1-792 FSWLFKLSDSRSHLHTTKMDGSTDSNTMSAGWEHSEENEEDRDKHLSFSGSGIDDDEDFI XP_004852098.1/1-697 ---------------------STDSNTMSKGWAPSEENEEDIDIHLSFSGSGIDDDEDFI .*.*** . ** .****:: * : .************* ENSMUSP00000005218/1-780 SSTIASTPRVSARTEDNQDWTQWKPNHSNPEVLLQTTTRMADIDRISTSAHGENWTPEPQ ENSRNOP00000009000/1-779 SSTIATTPWVSAHTKQNQERTQWNPIHSNPEVLLQTTTRMTDIDRNSTSAHGENWTQEPQ ENSP00000398632/1-742 SSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAH ENSCPOP00000007016/1-792 SSTISTTPRVSDHTKQYQDWNQWKPSHSSTEVLLQTTTRMTDVDRNGTSVYEESWTQDAQ XP_004852098.1/1-697 SSTISTTPRVSDHTKQFQDWIQWKPSHSNTEVLLQTTTRMTDVDRNGTSVHGEDWTQDAQ ****::** . :*:: *: **:* **..**********:*:** .*:.: .*. :.: ENSMUSP00000005218/1-780 PPFNNHEYQDEEETPHATSTT---PNSTAEAAATQQETWFQNGWQGKNPPTPSEDSHVTE ENSRNOP00000009000/1-779 PPFNNHEYQDEEETPHATSTTWAAPNSTTEEAATQKEKWFENEWQGKNPPTPSEDSHVTE ENSP00000398632/1-742 PPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTT ENSCPOP00000007016/1-792 PPLIHHEHPDKEETPHPPSTTWAAPSSTAEETATQKEQWSEDGWHGEYPQTPREDSGSTA XP_004852098.1/1-697 PPVIHHEHQDSEETPHSTSTTWAAPSSTTEETATQKEQWFEREWHGEYPQTPREDSDSTT **. :**: :.*****..** *.**:* :***:* * *: ** *** * ENSMUSP00000005218/1-780 GT-TASAHNNHPSQRITTQSQEDVSWTDFFDPISHPMGQGHQTESK-DTDSSHSTTLQPT ENSRNOP00000009000/1-779 GT-TASGHNNHPSQRMTTQSQEDVSWTDFFDPISHPMGQGHQTESK-DTDSSHSTTLQPT ENSP00000398632/1-742 GTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPT ENSCPOP00000007016/1-792 GT-TVSAHDSHPSQRMTTQSQEDSSWTEFFDPVSHPMRRGQQTEKTMDMDTSHS-TIQPT XP_004852098.1/1-697 GT-TVSAHSSRPSQRMTTQSQEDISWTEFFDPISHPMGRGHQTERRMDVDTSHSASVQPT ** :.*.* .:* * ** * ** ***:**:*:**** :*:*: * *:*** ::*** ENSMUSP00000005218/1-780 AAPNTHLVEDLNRTGPLSVTTPQSHSQNFSTLHGEPEEDENHPTTSILPSSTKSGAKDAR ENSRNOP00000009000/1-779 AAPNTHLVEDLNRTGPLSVTTPQSHSQNFSTLPGELEEGEDHPTTSVLPSSTKS---GAR ENSP00000398632/1-742 ANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGR ENSCPOP00000007016/1-792 AVPNTDLVEDLNRTRPHSVTTQQSDSQSFSTSHGELEEDKEQPTTSTLTSGNRHPAIEGR XP_004852098.1/1-697 ADPNTDLVEDLDRTRPLSVTTQQSDSQSFSTSHGELEEDKDHPTTSTLTSGNRDPAKGGR * *** *****:** * *:** **.**.*** **.:::**** *.*..: .* ENSMUSP00000005218/1-780 RGGSLPTDTTTSVEGYTFQYPDTMENGTLFPVTPAKTEVFGETEVTLATDSNVNVDGSLP ENSRNOP00000009000/1-779 RGGSLPRDTTTSLEGYTPQYPDTMENGTLFPVTPAKTEVFGETEGTVATDSNFNVDGSLP ENSP00000398632/1-742 RDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTV-GDSNSNVNRSLS ENSCPOP00000007016/1-792 RDGNLSEDSTTSLEGYTPHYPDTKENRTLIPVTPASTGAFGETEVTVVGEHNYDVDHHLP XP_004852098.1/1-697 RGANLPEDSTTSLEGYTPHYPETKENRTLIPVTPANTGAIGETEVTVVEEPNSDVDHSLP *. . . .:** :**** :**.* *. *::***.*.* :* * *: : * :*: *. ENSMUSP00000005218/1-780 GDRDSSKDSRGSSRTVTHGSELAGHSSANQDSGVTTTSGPMRRPQIPEWLIILASLLALA ENSRNOP00000009000/1-779 GDGDSSMDPRGGFDTVTHGSELAGHSSGNQDSGVTTTSGPARRPQIPEWLIILASLLALA ENSP00000398632/1-742 GDQDTF-HPSGGSHT-THGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALA ENSCPOP00000007016/1-792 GDQDSSVDPNRGSHT-TSDSASHGRASGTQ-GGANTTSAPIRRAQIPEWLIILASLLALA XP_004852098.1/1-697 GDQDTFIDPNERSHT-TSDSKSDGHSSGTR-AGASTPSPPQRRPQIPEWLIILASLLALA ** *: .. * * .* *:: ..: .*..*.* * * .**************** ENSMUSP00000005218/1-780 LILAVCIAVNSRRRCGQKKKLVINGGNGTVEDRKPSELNGEASKSQEMVHLVNKEPSETP ENSRNOP00000009000/1-779 LILAVCIAVNSRRRCGQKKKLVINSGNGTVEDRKPSELNGEASKSQEMVHLVNKEPTETP ENSP00000398632/1-742 LILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETP ENSCPOP00000007016/1-792 LILAVCIAVNSRRRCGQKKKLVINNGNGKMEDRKPSGLNGEASKSQEMVHLVNKEPSETP XP_004852098.1/1-697 LILAVCIAVNSRRRCGQKKKLVINNGNGAVEDRKPSGLNGEASKSQEMVHLVNKEPSETP ************************.*** :****** ******************.:*** ENSMUSP00000005218/1-780 DQCMTADETRNLQSVDMKIGV ENSRNOP00000009000/1-779 DQFMTADETRNLQSVDMKIGV ENSP00000398632/1-742 DQFMTADETRNLQNVDMKIGV ENSCPOP00000007016/1-792 DQFMTADETRNLQNVDMKIGV XP_004852098.1/1-697 DQFMTADETRNLQNVDMKIGV ** **********.*******