CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000006979/1-1026 ---------------------------------------------------------PHT XP_004872863.1/1-1102 MPPRQPARPAGGGLSREFCKLLPALSHSPLGGLGSGSGSVAPGQGRAGAMGS---RTPAS ENSP00000293379/1-1049 -------------------------------------------------MGS---RTPES ENSMUSP00000023128/1-1053 -------------------------------------------------MGSWTPRSPRS ENSRNOP00000052152/1-1098 -APRQPTRRPGGGPSRELGKLLPALSHSPLGGLGSGSGSVAPGQGRTGAMGSWTPRSPRS * : ENSCPOP00000006979/1-1026 PYKGS---------------------LCPPPEGVGGFNLDSEAPAVLLGPPGSFFGYSVE XP_004872863.1/1-1102 PLRAVQPRWGARRRPALPGLLPLFLLLLPPPPGVGGFNLDAEAPAVLSGPPGSFFGYSVE ENSP00000293379/1-1049 PLHAVQLRWGPRRRPP---LLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVE ENSMUSP00000023128/1-1053 PLHAVLLRWGPRRLPP---LLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVE ENSRNOP00000052152/1-1098 PLHAVLLRWGPRRLPP---LLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVE * :. * *** *******:****** *****:**:*** ENSCPOP00000006979/1-1026 FYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYFCPWGTSPGQCMPIEFDSKGSRNLESSL XP_004872863.1/1-1102 FYRPGTVGVSVLVGAPKANTSQPGVVQGGAVYFCPWSASPGQCTPIGFDSKGPRILESSL ENSP00000293379/1-1049 FYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSL ENSMUSP00000023128/1-1053 FYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCTTIQFDSKGSRILESSL ENSRNOP00000052152/1-1098 FYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCSTIQFDSKGSRILESSL ***** ******************:******.***.:** ** .* *****.* ***** ENSCPOP00000006979/1-1026 SSAEGKEPVEYKSLQWFGATIRAHGSSILACAPLYSWRTEKE-PLVDPVGTCYLSTGNFT XP_004872863.1/1-1102 SGTEEQEPVEYKSLQWFGATIRAHGSSILACAPLYSWRTEKEPPLNDPVGTCYLSTGNFT ENSP00000293379/1-1049 SSSEGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKE-PLSDPVGTCYLSTDNFT ENSMUSP00000023128/1-1053 YSAKGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKD-PQNDPVGTCYLSTENFT ENSRNOP00000052152/1-1098 YS---EEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKD-PQNDPVGTCYLSTENFT . :**************:********************: * ********** *** ENSCPOP00000006979/1-1026 RILEYAPCRSDFSSAAGQGYCQGGFSAEITKTGRVVLGGPGSYFWQGQILSATQEQIEES XP_004872863.1/1-1102 RILEYAPCRSDFGSAAGQGYCQGGFSAEITKTGRVVLGGPGSYFWQGQILSATQEQIADS ENSP00000293379/1-1049 RILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAES ENSMUSP00000023128/1-1053 RILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISES ENSRNOP00000052152/1-1098 RILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISES ************. **************:**************************** :* ENSCPOP00000006979/1-1026 YYPEYLINLVQGQLQTRQASSIYDDSYMGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVT XP_004872863.1/1-1102 YYPEYLINLVQGQLQTRQASSIYDDSYMGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVT ENSP00000293379/1-1049 YYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVT ENSMUSP00000023128/1-1053 YYPEYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVT ENSRNOP00000052152/1-1098 YYPQYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVT ***:**** ************:*****:******************************** ENSCPOP00000006979/1-1026 ILNGSDIRSLYNFSGEQMASYFGYAVAATDINGDGLDDLLVGAPLLMERTADGRPQEVGR XP_004872863.1/1-1102 ILNGSDIRSLYNFSGEQMASYFGYAVAATDINGDGLDDLLVGAPLLMDRTADGRPQEVGR ENSP00000293379/1-1049 ILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGR ENSMUSP00000023128/1-1053 VLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGR ENSRNOP00000052152/1-1098 VLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGR :******:****.***************** ****************:**.********* ENSCPOP00000006979/1-1026 VYIYMQHPAGIDPTPTLSLTGYDEFGRFGSSLTPLGDLDQDGYNDVAVGAPFGGETQQGV XP_004872863.1/1-1102 VYVYLQHLAGMDPTPTLTLTGLDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGV ENSP00000293379/1-1049 VYVYLQHPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGV ENSMUSP00000023128/1-1053 VYIYLQRPAGIDPTPTLTLTGQDEFSRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGV ENSRNOP00000052152/1-1098 VYIYLQHPEGIEPTPSLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGV **:*:*: *::***:*:*** ***.*********************:*******:**** ENSCPOP00000006979/1-1026 VFVFPGGPGGLGSKPSQVLQPLWAAGHTPDFFGSALRGGQDLDSNGYPDLIVGSFGVDKA XP_004872863.1/1-1102 VFVFPGGPGGLGSKPSQVLQPLWAVGHTPDFFGSALRGGQDLDSNGYPDLIVGSFGVDKA ENSP00000293379/1-1049 VFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKA ENSMUSP00000023128/1-1053 VFIFPGGPGGLSTKPSQVLQPLWAAGRTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKA ENSRNOP00000052152/1-1098 VFIFPGGPGGLNTKPSQVLQPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKA **:********.:***********..:************:***.**************** ENSCPOP00000006979/1-1026 VVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVPNSIGFTV XP_004872863.1/1-1102 VVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVPDSIGFTV ENSP00000293379/1-1049 VVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTV ENSMUSP00000023128/1-1053 LVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEV ENSRNOP00000052152/1-1098 LVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEV :*******:**********:****************:***************.:**** * ENSCPOP00000006979/1-1026 ELQLDWQKQKGGIRRALFLASKQATLTETLLIQNGAQEECREMKIYLRNESEFRDKLSPI XP_004872863.1/1-1102 ELQLDWQKQKGGIRRALFLASKQATLTETLLIQNGAREECREMKIYLRNESEFRDKLSPI ENSP00000293379/1-1049 ELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPI ENSMUSP00000023128/1-1053 ELQLDWQKQKGGVRRALFLTSKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPI ENSRNOP00000052152/1-1098 ELQLDWQKQKGGVRRALFLASKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPI ************:******:*:*****:********:*:********************* ENSCPOP00000006979/1-1026 HIALNFSLDPKAPTDSHGLRPVLHYQSKNRIEDKAQILLDCGEDNICVPDLQLEVFGDQN XP_004872863.1/1-1102 HIALNFSLDPEAPTDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNVCVPDLQLEVFGDQN ENSP00000293379/1-1049 HIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQN ENSMUSP00000023128/1-1053 HIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLDVYGEKK ENSRNOP00000052152/1-1098 HIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLAVYGEKK **********:** *******.******.****************:******* *:*::: ENSCPOP00000006979/1-1026 RVYLGNKDTLNLTFHAQNVGEGGAYEAELRVTAPLEAEYIGFVRNPGNFSSLSCDYFTVN XP_004872863.1/1-1102 RVYLGNKDSLILTFHAQNVGEGGAYEAELRVTAPLEAEYIGLVRNPGNFSSLSCDYFTVN ENSP00000293379/1-1049 HVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVN ENSMUSP00000023128/1-1053 HVYLGDKNALNLTFHAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVN ENSRNOP00000052152/1-1098 HVYLGDKNALNLTFLAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVN :****:*::* *** ***:*************** **** *:**:************:** ENSCPOP00000006979/1-1026 QS-LLVCDLGNPMKAGASLWGGLRFTVRHLQDTQENIQFDFQILSKNLNNSQSDVVSYRL XP_004872863.1/1-1102 QS-LLVCDLGNPMKAGASLWGGLRFTVRHLQDTKETIQFDFQILSKNLNNSQSDVVSFRL ENSP00000293379/1-1049 QSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRL ENSMUSP00000023128/1-1053 QSRQLVCDLGNPMKAGTSLWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNVVSFPL ENSRNOP00000052152/1-1098 QSRQLVCDLGNPMKAGTSIWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNMVSFPL ** ************:*:******** **:**::.*****************::**: * ENSCPOP00000006979/1-1026 SVEAQAEVSLNGVSKPEAVLFPASDWHPPNQPQTEGDVGPAVHHVYELINHGPSTISQGV XP_004872863.1/1-1102 SVEAQAQVSLNGVSKPEAVIFPVSDWHPQNQPQTEGDVGPAVHHVYELINHGPSTIGRGV ENSP00000293379/1-1049 SVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGV ENSMUSP00000023128/1-1053 SVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEEDLGPAVHHVYELINQGPSSISQGV ENSRNOP00000052152/1-1098 SVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEGDLGPAVHHVYELINQGPSSISQGV ******:*:**********:**.***:* :***.* *:************:***:*.:** ENSCPOP00000006979/1-1026 LDISCPQTWEGHQLLYVTRVTGLPNCTTNYTPNLQGLELDPEEAPHHLQRRDAPGRSPAS XP_004872863.1/1-1102 LDISCPQAWEGHQLLYVTRVTGLSNCTTNYTPNLQGLELDPEESPHHLQRRDAPGRSPAS ENSP00000293379/1-1049 LELSCPQALEGQQLLYVTRVTGL-NCTTNHPINPKGLELDPEGSLHHQQKREAPSRSSAS ENSMUSP00000023128/1-1053 LELSCPQALEGQQLLYVTKVTGLSNCTSNYTPNSQGLELDPETSPHHLQKREAPGRSSTA ENSRNOP00000052152/1-1098 LEISCPQALEGQQLLYVTKVTGLNNCTSNYTPNSQGLELDPEVSPHHLQRREAPGRSSTT *::****: **:******:**** ***:*:. * :******* : ** *:*:**.**.:: ENSCPOP00000006979/1-1026 SGPQVLKCPEAECFRLHCDLGPVPRQQSLSLQLHFRVWAKTFLQKEQLPFSLQCEAEYKA XP_004872863.1/1-1102 SGPQVLKCPEAECFRLHCELGPLPRQQSLSLQLHFRVWAKTFLQKEQQPFSLQCEAEYKA ENSP00000293379/1-1049 SGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQPFSLQCEAVYKA ENSMUSP00000023128/1-1053 SGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQREYQPFSLQCEAVYEA ENSRNOP00000052152/1-1098 SGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQQEYQPFSLQCEALYEA **.*:******:****:*::**: :*:* ***************:* ******** *:* ENSCPOP00000006979/1-1026 LKMPYRILPQQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKL XP_004872863.1/1-1102 LKMPYRILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKL ENSP00000293379/1-1049 LKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKL ENSMUSP00000023128/1-1053 LKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKL ENSRNOP00000052152/1-1098 LKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKL *****:***:*****: ************** ***********************:**** ENSCPOP00000006979/1-1026 GFFKRSLPYGTAMEKAQLKPPATSDA XP_004872863.1/1-1102 GFFKRSLPYGTAMEKAQLKPPATSDA ENSP00000293379/1-1049 GFFKRSLPYGTAMEKAQLKPPATSDA ENSMUSP00000023128/1-1053 GFFKRSLPYGTAMEKAQLKPPATSDA ENSRNOP00000052152/1-1098 GFFKRSLPYGTAMEKAQLKPPATSDA **************************