CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000110550/1-996 MTDPEVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLETGDQAGI ENSRNOP00000018782/1-776 MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGI ENSP00000418385/1-1024 MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGI ENSCPOP00000006948/1-889 MADPTVCCFITKILCAHGGRLSLDALLEKIQLSEAQLLEVLKEAGPDRFVVLETGGRAGV XP_004851311.1/1-901 MADPTVCCFVTKILCAHGGRLSLDALLEKIELSEAQLLEVLKEAGPDRFVVLETGGRAGV *:** * **:**********::*: ** :* *.*.** *:*: *******:****..**: ENSMUSP00000110550/1-996 TRSVVATTRARVCRRKYCQRP-CDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQ ENSRNOP00000018782/1-776 TRSVVATTRARVCRRKYCQRP-CDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQ ENSP00000418385/1-1024 TRSVVATTRARVCRRKYCQRP-CDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFK ENSCPOP00000006948/1-889 TRSVVATTRARVCRRKFCDRP-CENLHLCKLNLLGRCHYSQSERNLCKYSHEVLSEPNFR XP_004851311.1/1-901 TRSVVATTRARVCRRKFCERSSCDNLHLCKLNLLGRCHYSQSERNLCKYSHDVLSEKNFQ ****************:*:*. *:.************:*:**:********:**** **: ENSMUSP00000110550/1-996 VLKNHELSGLNQEELAVLLVQSDPFFMPEICKSYKGEGRKQICGQPQPCERLHICEHFTR ENSRNOP00000018782/1-776 ILKNHELSGLNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTR ENSP00000418385/1-1024 VLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTR ENSCPOP00000006948/1-889 VLKNHELSGLNQEQLAVLLVQSDPFFMPEICKSYKGEGRKQICNQQPPCERLHICEHFTR XP_004851311.1/1-901 VLKNHELSGLNQEQLAVLLLQSDPFFMPEICKSYKGEGRKQICNQQPPCERLHICEHFTR :**********:*:** **:******:************:* *.* **.*****:**** ENSMUSP00000110550/1-996 GNCSYLNCLRSHNLMDRKVLAIMREHGLSSDVVQNIQDICNNKHTRRNPPSMRAPHPHRR ENSRNOP00000018782/1-776 GNCSYLNCLRSHNLMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRR ENSP00000418385/1-1024 GNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRR ENSCPOP00000006948/1-889 GNCSYPNCLRSHNLMDRKVLAIMRDHGLSPDVVQNIQDICNSKHMRRNPSVPKLP--GRR XP_004851311.1/1-901 GNCSYPNCLRSHNLMDRKVLAIMRDHGLSPAVVQNIQDICNNKHMRRNPPGSKTP-VHRR *** : **************:***:***.. **********.** ::**. : . ** ENSMUSP00000110550/1-996 GGAHRDRSKSRDRFHHNSLEVL--STVSPLGSGPPSPDVTGCKDPLEDVSA-DVTQKFKY ENSRNOP00000018782/1-776 GGAHRDRSKSRDRFLHNSLEFL-SPVVSPLGSGPPSPDVTSCKDSLEDVSV-DVTQKFKY ENSP00000418385/1-1024 NMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTY ENSCPOP00000006948/1-889 NIPGRGRSKSRDRASQDVKEFL--PSPSAHKPSDHNSDGTSSRATLGDRLADDITHKLTF XP_004851311.1/1-901 ARAARGRSKSRDRVSQDIKEFL--PSASAHKSGTPSPDGTDSRASLEDDPMDDLIHKFEF . * ******* :. *.* . *. . ..* . : .* * *: :*: : ENSMUSP00000110550/1-996 LGTQDRAQLSSVSSKAAGVRGPSQMRASQEFLEDGDPDGLFSRN--RSDSSTSRTSA--- ENSRNOP00000018782/1-776 LGTHDRAQLSPVSSKAAGVQGPSQMRASQEFSEDGNLDDIFSRN--RSDSSSSRASA--- ENSP00000418385/1-1024 LGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNW ENSCPOP00000006948/1-889 IENEDPAQLSSVSSKAADLGGPGQVGANQRFSENGLPDSLFYSN--RSNPTSNSTPVSNQ XP_004851311.1/1-901 LETPDCTQPSSVSSKAAGLGRPGQVGTSQRFLENGIPDGLFHSN--QSHLASNSTPASNQ : . * :: .. ****:.: ..* :.*.* *:* :.:: * : ::. :.. ENSMUSP00000110550/1-996 ------------------------AGFPLVAAQRNEAGAMK--MGMPSGHHVEVKGKNE- ENSRNOP00000018782/1-776 ------------------------AK----VAQRNEAVAMK--MGM------EVKGKKEA ENSP00000418385/1-1024 KSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGT ENSCPOP00000006948/1-889 KGSPSWLNAQATRKESVFFPSPGVPASLPDITQTPKALTSRMPMGMLSSDHVDIKAKSGT XP_004851311.1/1-901 KGSPSWLNAQGTGKESEFFPSQAVPSFPLDSTQTLKALNSRKVVGMLSSDHMNVKDKSGS . * :* : *: :: *. ENSMUSP00000110550/1-996 -DIDRVPFLNSYIDGVTMEEATVSGILGKRATDNGLEEMILSSNHQKSVAKTQDPQTAGR ENSRNOP00000018782/1-776 PDIDRVPFLNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGR ENSP00000418385/1-1024 QDIQPGPLFNNNADGVATDITSTRSL-NYKSTSSGHREISSPR-IQDAGPASRDVQATGR ENSCPOP00000006948/1-889 PDTQQVPLFNNNL-GLGMNM-------NFGTTSNGQRETALLS-YQDSRTTL-DHK-IGN XP_004851311.1/1-901 QDIQRIPIFSRNADGVAMNM-------NFGKTA--QREMALSS-YQDSRATPRDLH-IGS * : *::. *: : . * .: . . * : * ENSMUSP00000110550/1-996 ITDS-GQDTAFLHSKYEENPAWPGTSTHNGPNGFSQIMDETPNVSKSSPTGFGIKSAVTG ENSRNOP00000018782/1-776 ITDS-GQDKAFLQSKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAG ENSP00000418385/1-1024 IADDADPRVALVNGKYKGKTLWASTFVHDIPNGSSQVVDKTTDVEKTGATGFGLTMAVKA ENSCPOP00000006948/1-889 ITND-DPGVAFLND---------------------------------------------- XP_004851311.1/1-901 IASD-DARVAFLND---------------------------------------------- *:.. . *:::. ENSMUSP00000110550/1-996 GKEAVYSGVQSLRSHVLAMPGETTTPVQGSNRLPPSPLSSSTSHRVAASGSPGKSSTHAS ENSRNOP00000018782/1-776 GKEAVYSGVQSPRSQVLAMPGETTTPVQ-SNRLPQSPLS-SSSHRAAASGSPGKNSTHTS ENSP00000418385/1-1024 EKDMLRTGSQSLRNLVPTTPGESTAPAQ-VSTLPQSPAALSSSNRAAVWGAQGQNCTQVP ENSCPOP00000006948/1-889 ------------------------------------------------------------ XP_004851311.1/1-901 ------------------------------------------------------------ ENSMUSP00000110550/1-996 VSPASEPSRMMMMMSDPAEYSLCYIVNPVSPRMDDHGLKEICLDHLYRGCQ-QVNCNKNH ENSRNOP00000018782/1-776 VSPAIESSR---MTSDPDEYLLRYILNPL-FRMDNHGPKEICQDHLYKGCQ-QSHCDRSH ENSP00000418385/1-1024 VSSASELTR---KTTGSAQYSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVH ENSCPOP00000006948/1-889 --------------------SGSDVTSTT-SRMGCHGAQDICIDYLRNCCQFNSSCSKIH XP_004851311.1/1-901 --------------------SISDITNTT-SRMGNLGPEGICVDYLHNRCQPNSDCSKIH : .. *:. . : ** *:* . * : *.: * ENSMUSP00000110550/1-996 FHLPYRWQLFILPTWMDFQDMEYIERAYCDPQIEIIVIEKHRINFKKMTCDSYPIRRLST ENSRNOP00000018782/1-776 FHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELILIENHQINFQKMTCDSYPIRRLST ENSP00000418385/1-1024 FHLPYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLST ENSCPOP00000006948/1-889 FHLPYQWQLLMTHTWVDFQDMEKIEKAYCDPRNVIISVGNHTLDFQKMTCGLRPIRRIST XP_004851311.1/1-901 FPLPYRWQVLMSHTWKDLEDMEKIEKAYCNPRSHVLSIENHILDFQKMTYALKPIRRISS * ***:**::: ** *::.** **:.**:* : : .: ::*: *: ****:*: ENSMUSP00000110550/1-996 PSFVEKTLNSVFTTKWLWYWRNELNEYTQYGHESPSHTSSEINSAYLESFFHSCPRGVLQ ENSRNOP00000018782/1-776 PSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPGHTSSDINSAYLESFFQSCPRGVLP ENSP00000418385/1-1024 PSSVTKPANSVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVP ENSCPOP00000006948/1-889 PSSGLNLANSVFATKWIWYWKNELGNWIQYGERSNNQPGSDVDSSYLESFFQSCPRGVVP XP_004851311.1/1-901 PSSGMNQASTVFTTKWIWYWENESGEWIQYGKGSNNQPGSNIDSSYLESFFQKCPRGVVP ** : .:**:***:***.** . : ***. . : .*:::*:****:::.*****: ENSMUSP00000110550/1-996 FHAGSQNYELSFQGMIQTNIASKTQRHVVRRPVFVSSKDVEQKRRGPD----------HQ ENSRNOP00000018782/1-776 FQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDVEQKRRAPE------------ ENSP00000418385/1-1024 FQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPD----------HQ ENSCPOP00000006948/1-889 FQAGVRNYELSFQGMIQTNIVSKTQKDVVRRPTFVSSLDVEQMRRRPD----------RQ XP_004851311.1/1-901 FQAGTRNYELSFQGMIQTNIASKTQKNVVRRPEFVSARDVEQMRRGPDPQRVQFSASSPQ *:** ::*************.****:.*:*** **. *:* :* *: ENSMUSP00000110550/1-996 PVMPQADALTLFSSPQRNASTVSSNEYEFIELNNQDEEYAKISEQFKASMKQFKIVTIKR ENSRNOP00000018782/1-776 ------------------------------------------------------------ ENSP00000418385/1-1024 PAKTSSVSLTATFRPQEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKK ENSCPOP00000006948/1-889 PAQTPPEAVLSTFVPQRDVGSLPLNGYKLIDLSNDSMEYTMIRDCFKESMKNFKIEKIKK XP_004851311.1/1-901 PVHTPPEAVGSTFVPQWDVLSPTSSGYKLLDLDNQSLEYATIRDNFKESMKNFKIEKIKK ENSMUSP00000110550/1-996 IWNQKLWDTFERKKQKMKNKTEMFLFHAVGRIHMDYICKNNFEWILHGNREIRYGKGNYF ENSRNOP00000018782/1-776 ------------------------------------------------------------ ENSP00000418385/1-1024 IENSELLDKFTWKKSQMKEE-GKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYF ENSCPOP00000006948/1-889 IHNPELLNSFERRRLLMTEKKERLLFYATSSTHVDSICANNFVWTYDGAQTKKYGQGNHF XP_004851311.1/1-901 IHNPELLNSFERRRLNMTEKRERLLFYATSRTHVDSICANNFMWNLHGTHENKYGKGNHF ENSMUSP00000110550/1-996 TKEAMYSHKSCSYDSRGTVMFVARVLVGSVIEGNMTLSSPPALYDSCVDTRLNPSVFVIF ENSRNOP00000018782/1-776 ------------------------------------------------------------ ENSP00000418385/1-1024 AKDAIYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIF ENSCPOP00000006948/1-889 SKEAIYSHKNCLYDARNIVMFVARVLAGDFIEGNMIYKSPPPPYNSCVDTMLNPSVFVIF XP_004851311.1/1-901 SKDAIYSHKNCLYDARNIVMFVARVLAGDFIEGNMTFVSPPPPYNSCVDTMLNPSVFVIF ENSMUSP00000110550/1-996 RKEQIYPEYVIEYMELEKEKGCIIS ENSRNOP00000018782/1-776 ------------------------- ENSP00000418385/1-1024 QKDQVYPQYVIEYTE---DKACVIS ENSCPOP00000006948/1-889 QKDQIYPAYLIEYTETDKEKSCVIS XP_004851311.1/1-901 RNDQVYPAYLIEYSEPDREKACVIS