CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000116071/1-699 ------------------------------------------------------------ ENSRNOP00000019447/1-780 MMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGGGGPGSGPGAATSASAA ENSP00000365198/1-775 MMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELS-GGGGPGPGPGAAASASAA ENSCPOP00000006846/1-636 ------------------------------------------------------------ XP_004850378.1/1-773 MMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLVELS--GGGPGPAPGAAASASVA ENSMUSP00000116071/1-699 ---------------------XLLREEVVQLQEEVHLLRQMKEMLAKDLEESQGGKCSEV ENSRNOP00000019447/1-780 AVTVADSAVATMENHQH-GAQVLLREEVVQLQEEVHLLRQMKEMLAKDLEESQGGKCSEV ENSP00000365198/1-775 ----GDSAATNMENPQL-GAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEV ENSCPOP00000006846/1-636 ------------------------------------------------------------ XP_004850378.1/1-773 ------AAAENMENQQQPSAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKASEV ENSMUSP00000116071/1-699 LSATELRVQLVQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR ENSRNOP00000019447/1-780 LSATELRVQLVQKEQELARAREALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR ENSP00000365198/1-775 LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR ENSCPOP00000006846/1-636 -------------------------AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR XP_004850378.1/1-773 LSATELRVQLAQKEQELARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLR *********************************** ENSMUSP00000116071/1-699 DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAAALRSQLDLKDNRMK ENSRNOP00000019447/1-780 DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAAALRSQLDLKDNRMK ENSP00000365198/1-775 DFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMK ENSCPOP00000006846/1-636 DFIRSYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAAALRSQLDLKDNRMK XP_004850378.1/1-773 DFIRSYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHAAALRSQLDLKDNRMK ****.****************************************:************** ENSMUSP00000116071/1-699 ELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLY ENSRNOP00000019447/1-780 ELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLY ENSP00000365198/1-775 ELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLY ENSCPOP00000006846/1-636 ELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLY XP_004850378.1/1-773 ELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLY ************************************************************ ENSMUSP00000116071/1-699 HSHPPHPADRQ-VRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPG ENSRNOP00000019447/1-780 HSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPG ENSP00000365198/1-775 HSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPG ENSCPOP00000006846/1-636 HSHPPHPADRQAVRVSPCHSRQPSVISDASVAEGDRSSTPSDINSPRHRTHSLCNGDSPG XP_004850378.1/1-773 HSHPPHPADRQAVRVSPCHSRQPSVISDASVAEGDRSSTPSDINSPRHRTHSLCNGDSPG *********** ******************.***************************** ENSMUSP00000116071/1-699 PVQKSLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCS ENSRNOP00000019447/1-780 PVQKSLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCS ENSP00000365198/1-775 PVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCS ENSCPOP00000006846/1-636 PVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCS XP_004850378.1/1-773 PVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCS ****.******************************************************* ENSMUSP00000116071/1-699 PTRHSLSLSEGEEQMDRLQHVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACAENVKS ENSRNOP00000019447/1-780 PTRHSLSLSEGEEQMDRLQHVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACAENVKS ENSP00000365198/1-775 PTRQSLSLSEGEEQMDRLQQVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACTENVKS ENSCPOP00000006846/1-636 PTRHSLSLSEGEEQMDRLQHVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACAENVKS XP_004850378.1/1-773 PTRHSLGLSEGEEQLDRLQHVELVRTTPMSHWKASTVQAWLEVVMAMPMYVKACAENVKS ***:**.*******:****:**************.*******************:***** ENSMUSP00000116071/1-699 GKVLLSLSDEDLELGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAADLDHHWVAKAWLN ENSRNOP00000019447/1-780 GKVLLSLSDEDLELGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAADLDHHWVAKAWLN ENSP00000365198/1-775 GKVLLSLSDEDLQLGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAAELDHHWVAKAWLN ENSCPOP00000006846/1-636 GKVLLSLSDEDLELGLGVCSSLHRRKLRLAIEDYRDAEAGRSLSKAAELDHHWVAKAWLN XP_004850378.1/1-773 GKVLLSLSDEDLELGLGVCSSLHRRKLRLAIEDYRDAEAGRSLCKAAELDHHWVAKAWLN ************:******************************.***:************ ENSMUSP00000116071/1-699 DIGLSQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREA ENSRNOP00000019447/1-780 DIGLSQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREA ENSP00000365198/1-775 DIGLSQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREA ENSCPOP00000006846/1-636 DIGLSQYSQAFHNHLVDGRVLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREA XP_004850378.1/1-773 DLGLSQYSQAFHNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREA *:*********:*******:**************************************** ENSMUSP00000116071/1-699 LQERRARCETQNTDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAM ENSRNOP00000019447/1-780 LQERRARCETQNTDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAM ENSP00000365198/1-775 LQERRARCETQNIDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAM ENSCPOP00000006846/1-636 LQERRARCETQNTDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAM XP_004850378.1/1-773 LQERRARCEMQNTDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAM ********* ** *********************************************** ENSMUSP00000116071/1-699 ATALGIPSGKHILRRHLAEEMSTIFHPSNSTGIRESERFGTPPGRASSITRAGREDSGGN ENSRNOP00000019447/1-780 ATALGIPSGKHILRRHLAEEMSTVFHPANSTGIRESERFGTPPGRASSITRAGKEDGSSN ENSP00000365198/1-775 ATALGIPSGKHILRRHLAEEMSAVFHPANSTGIREAERFGTPPGRASSVTRAGKEENSSG ENSCPOP00000006846/1-636 ATALGIPSGKHILRRHLAEEMSAIFHPSSSIGTREAERFGSPPRRASSVTRAGKEENSGG XP_004850378.1/1-773 AAALGIPSGKHILRRHLAEEMSAVFHPASSTGTREAERFGTPSRRASSVTRAGKEENSGG *:********************::***:.* * **:****:*. ****:****:*:.... ENSMUSP00000116071/1-699 SKHRAGRLPLGKIGRGFSSKEPDFHDDYGSLENEDCGDEDLQGRPEQCRLEGYGSLEVTN ENSRNOP00000019447/1-780 SKYRTGRLPLGKIGRGFSSKEPDYYDDYGSLENEDCGDDDLQGRPEQCRLEEYSSLEVTN ENSP00000365198/1-775 LKYKAGRLPLGKIGRGFSSKDPDFHDDYGSLQNEDCGDDDPQSRLEQCRLEGYNSLEVTN ENSCPOP00000006846/1-636 LKYKAGRLPLGKIGRGFSGKDLDFHDDYGSLQNEDCGDDDAQGRPEQCGLEGCNGLEVTN XP_004850378.1/1-773 LKYKAGRLPLGKIGRGFSSKDLDFHDDYGSLQNEDCGDDDPQTRPEQGCLEGCNGLEVTN *:::*************.*: *::******:******:* * * ** ** ..***** ENSMUSP00000116071/1-699 V ENSRNOP00000019447/1-780 V ENSP00000365198/1-775 V ENSCPOP00000006846/1-636 V XP_004850378.1/1-773 V *