CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000006728/1-1042 RGGKRGGGGDLGEGGPFFPAPAPAADVLRRFSVTAEGGLSPEQVTSARERHGPNELPTEE XP_004857289.1/1-1043 -----------MEEAYLLPV----ADVLRRFSVTAEGGLSPEQVTSARERYGPNELPTEE ENSP00000353072/1-1052 -----------MEAAHLLPA----ADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEE ENSMUSP00000021142/1-1038 -----------MEEAHLLSA----ADVLRRFSVTAEGGLSLEQVTDARERYGPNELPTEE ENSRNOP00000060212/1-1061 -----------MEEAHLLSA----ADVLRRFSVTAEGGLTLEQVTDARERYGPNELPTEE * . ::.. *****:*********: ***.****:******:** ENSCPOP00000006728/1-1042 GKSLWELVLEQFDNLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAVVG XP_004857289.1/1-1043 GKSLWELVLEQFDDLLVRILLLAALVSFVLAWFEEGEEITTAFVEPLVIMLILVANAIVG ENSP00000353072/1-1052 GKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVG ENSMUSP00000021142/1-1038 GKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVG ENSRNOP00000060212/1-1061 GKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVG ********:***::************************ ******************:** ENSCPOP00000006728/1-1042 VWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRL XP_004857289.1/1-1043 VWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRL ENSP00000353072/1-1052 VWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRL ENSMUSP00000021142/1-1038 VWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRL ENSRNOP00000060212/1-1061 VWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRL ************************************************************ ENSCPOP00000006728/1-1042 IEIKSTTLRVDQSILTGESVSVTKHEEAIPDPRAVNQDKKNILFSGTNIASGKAVGVVVA XP_004857289.1/1-1043 IEIKSTTLRVDQSILTGESVSVTKHRDVIPDPRAVNQDKKNMLFSGTNIASGKAVGVAVA ENSP00000353072/1-1052 IEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVA ENSMUSP00000021142/1-1038 IEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVA ENSRNOP00000060212/1-1061 IEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVA ************************* :.*************:*******:****:**.** ENSCPOP00000006728/1-1042 TGLHTELGKIRSQMAAVEPERTPLQRKLDEFGCQLSRAISVICVAVWIINIGHFADPAHG XP_004857289.1/1-1043 TGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFSDPAHG ENSP00000353072/1-1052 TGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHG ENSMUSP00000021142/1-1038 TGLQTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHG ENSRNOP00000060212/1-1061 TGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHG ***:**************************** ***:**********:******:***** ENSCPOP00000006728/1-1042 GSWLRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCT XP_004857289.1/1-1043 GSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCT ENSP00000353072/1-1052 GSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCT ENSMUSP00000021142/1-1038 GSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCT ENSRNOP00000060212/1-1061 GSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCT *******:**************************************************** ENSCPOP00000006728/1-1042 SVICSDKTGTLTTNQMSVCRMFVVAEAEAGSCRLHEFTISGTTYAPEGEVRQGEQPVRCG XP_004857289.1/1-1043 SVICSDKTGTLTTNQMSVCRMFVVAEAKAASCRLHEFTISGTTYTPEGEVQQGEQPVRCG ENSP00000353072/1-1052 SVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCG ENSMUSP00000021142/1-1038 SVICSDKTGTLTTNQMSVCRMFVVAEAEAGTCRLHEFTISGTTYTPEGEVRQGEQPVRCG ENSRNOP00000060212/1-1061 SVICSDKTGTLTTNQMSVCRMFVVAEAEAGACRLHEFTISGTTYTPEGEVRQGEQLVRCG ***************************.*.:* ***********:*****:**:* **** ENSCPOP00000006728/1-1042 QFDGLVELATICALCNDSALDYNEAKGIYEKVGEATETALTCLVEKMNVFDMDLQALSRV XP_004857289.1/1-1043 QFDGLVELATICALCNDSALDYNEAKAVYEKVGEATETALTCLVEKMNVFDMDLKTLSRV ENSP00000353072/1-1052 QFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRV ENSMUSP00000021142/1-1038 QFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRV ENSRNOP00000060212/1-1061 QFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRV **************************.:*********************** **: **** ENSCPOP00000006728/1-1042 ERAGACNAVIKQLMKKEFTLEFSRDRKSMSVYCTPTRPDPKTQGSKMFVKGAPESVLERC XP_004857289.1/1-1043 ERAGACNAVIKQLMKKEFTLEFSRDRKSMSVYCTPTCPDPKTQGSKMFVKGAPESVLERC ENSP00000353072/1-1052 ERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERC ENSMUSP00000021142/1-1038 ERAGACNSVIKQLMRKEFTLEFSRDRKSMSVYCTPTRADPKVQGSKMFVKGAPESVIERC ENSRNOP00000060212/1-1061 ERAGACNSVIKQLMRKEFTLEFSRDRKSMSVYCTPTRADPKAQGSKMFVKGAPESVIERC *******:******:********************* ..*. **************:*** ENSCPOP00000006728/1-1042 SSVRVGSRTAPLDSTSREQILAKIRDWGSGSDTLRCLALATRDVPPRKEDMQLDDCSKFA XP_004857289.1/1-1043 SSVRVGSRTAPLNTASREQILAKIRDWGSGSDTLRCLALATQDAPPRKEDMQLDDSSKFA ENSP00000353072/1-1052 SSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV ENSMUSP00000021142/1-1038 SSVRVGSRTAPLSTTSREHILAKIRDWGSGSDTLRCLALATRDTPPRKEDMHLDDCSRFV ENSRNOP00000060212/1-1061 SSVRVGSRTVPLSATSREHILAKIRDWGSGSDTLRCLALATRDTPPRKEDMQLDDCSQFV *********.** .:***:**********************:*.*******.***.*:*. ENSCPOP00000006728/1-1042 QYETDLTFVGCVGMLDPPRPEVAACIVRCHRAGIRVVMITGDNKGTAVAICRRLGIFEDS XP_004857289.1/1-1043 QYETNLTFVGCVGMLDPPRPEVAACITRCHRAGIRVVMITGDNKGTAVAICRRLGIFEDS ENSP00000353072/1-1052 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT ENSMUSP00000021142/1-1038 QYETDLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDT ENSRNOP00000060212/1-1061 QYETGLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDT ****.*********************.** :************************** *: ENSCPOP00000006728/1-1042 EDVAGKAYTGREFDDLSPEQQRHACLTARCFARVEPAHKSRIVEFLQSFNEITAMTGDGV XP_004857289.1/1-1043 EDVVGKAYTGREFDDLSPEQQRHACCTARCFARVEPAHKSRIVEYLQSFSEITAMTGDGV ENSP00000353072/1-1052 EDVAGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGV ENSMUSP00000021142/1-1038 EDVLGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGV ENSRNOP00000060212/1-1061 EDVLGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGV *** ******************:** ****************** ****.********** ENSCPOP00000006728/1-1042 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLI XP_004857289.1/1-1043 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI ENSP00000353072/1-1052 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLI ENSMUSP00000021142/1-1038 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLI ENSRNOP00000060212/1-1061 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLI *************************************************.********** ENSCPOP00000006728/1-1042 SSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPR XP_004857289.1/1-1043 SSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPH ENSP00000353072/1-1052 SSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPR ENSMUSP00000021142/1-1038 SSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRNPR ENSRNOP00000060212/1-1061 SSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPR ****************************************************** **.*: ENSCPOP00000006728/1-1042 EALISGWLLFRYLAIGVYVGLATVTAATWWFLYDAEGPRVTFYQLRNFLKCAEDNPLFTG XP_004857289.1/1-1043 EALISGWLFFRYLAIGVYVGLGTVAAATWWFLYDAEGPQVTFYQLRNFLKCSEDNPLFAG ENSP00000353072/1-1052 EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAG ENSMUSP00000021142/1-1038 EALISGWLFFRYLAIGVYVGLATVAAATWWFLYDTEGPQVTFYQLRNFLKCSEDNPLFAG ENSRNOP00000060212/1-1061 EALISGWLFFRYLAIGVYVGLATVAAATWWFLYDAEGPQVTFHQLRNFLKCSEDNPLFAG ********:************.**:******:**:***::.*:********:******:* ENSCPOP00000006728/1-1042 VDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHF XP_004857289.1/1-1043 VNCEVFESHFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHF ENSP00000353072/1-1052 IDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHF ENSMUSP00000021142/1-1038 IDCKVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHF ENSRNOP00000060212/1-1061 IDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHF ::*:****:**********************************:***** **.******* ENSCPOP00000006728/1-1042 LILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALKYLSRNHVDACIYPGILWRAL XP_004857289.1/1-1043 LILLVPPLPLIFQVTPLSGHQWVVVLQISLPVILLDEALKYLSRNHMEACLYPGILQTVL ENSP00000353072/1-1052 LILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALKYLSRNHMHACLYPGLLRTVS ENSMUSP00000021142/1-1038 LILLVPPLPLIFQVTPLSGRQWGVVLQMSLPVILLDEALKYLSRNHMD-----GVLGTFM ENSRNOP00000060212/1-1061 LILLVPPLPLIFQVTPLSGRQWGVVLQMSLPVILLDEALKYLSRHHVD-----GVLETFM *******************:** ****:****************:*:. *:* ENSCPOP00000006728/1-1042 QAWRRQPP-----TTSRTPDHTGLASL--------------------------------- XP_004857289.1/1-1043 RAWRRQLL-----TTSRTPDHTGKKGPEVNA---------GNRAESPATTSD-------- ENSP00000353072/1-1052 QAWSRQPL-----TTSWTPDHTGLASLGQGHSIVSLSELLREGGSREEMSQK-------- ENSMUSP00000021142/1-1038 QARSRQLP-----TTSRTPYHTGKKGPEVNP---------GSRGESPVWPSD-------- ENSRNOP00000060212/1-1061 QAWCKQPLPGPHATRGWLPG-CHFNGWEQTEEFVFIQERWTVSGLGPEKKARERLGLVSA :* :* * . * . ENSCPOP00000006728/1-1042 -- XP_004857289.1/1-1043 -- ENSP00000353072/1-1052 -- ENSMUSP00000021142/1-1038 -- ENSRNOP00000060212/1-1061 AS