CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000110519/1-835 MEPILINAQVQMWSAKAGMSKSRNALIETCVGKREVKLILYFSTGKIKTLQLHDNIKSVV ENSRNOP00000047375/1-827 MDPVLIHAQVQLWSAKAGMSKSRNAFIETFIGKREVKLILYFSTGKIKALQLYNNIKSVV ENSP00000359869/1-913 MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVV ENSCPOP00000006715/1-882 MSSIMVPGYAQIWSKRSGMSKTQNVFLEAVKGRKNFKLLIYFKTGKVKTFHLNNNIRSAS XP_004860172.1/1-900 MSSIMVHGYAQIWNKRTGMSEPQGVFIEAVKGRKNFKLLIYLRTGRVKTLKLNNNIKSVI * .::: . .*: . ::*:*:.: .::*: ::: :*::*: :*: .:::* :**:.. ENSMUSP00000110519/1-835 LQTYGEDQNYLHLTFKNNDFLFVEKLTTTDARRLKRFLDKTSQGSIRPA-RSDERCGE-- ENSRNOP00000047375/1-827 LRTYGEDQNYLHLTFKNNDFLFVEKLTTMDARRLKRFLDKIYQSNLRAARRSGERPGD-- ENSP00000359869/1-913 LKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGK-GGSVF ENSCPOP00000006715/1-882 FTSYGEDFTHLHLVFRNNGFLIVERLASTDAEQLKVFLASVPQDNSEPRMNPDEEDNESV XP_004860172.1/1-900 LQSYGANLSSLHVTFQNDGFLFVEKLSSTEAKQLKAFLDSVHQNCPEPHMSPDK--GEGP : :* : . **:.::*:. *::* *:: :*.:** ** *. .. ..: .. ENSMUSP00000110519/1-835 -PSTSAQELNGSGSSC--ETNSECFESPKESEMCMFRELSLLPSSSTFLHNVGLLENQFI ENSRNOP00000047375/1-827 -PSTSAQELSSSPPEGHLKASSACFESAKESEMCLFRQLPLLPPSSASLNAVGLLESQFM ENSP00000359869/1-913 SSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCG-ELSENQHK ENSCPOP00000006715/1-882 SASTATQISESSLPSIYNKSDEECSGTNQESRKYI-RDTSLLSSKSVLPSK---KSKTQR XP_004860172.1/1-900 STCTGTQTRKTSLPKVREESGEGCSGTDKNRKRSAHRKKPLATSKSSTLTN-EELENQQR . * : . * . ::.. . : : .* ... .. ENSMUSP00000110519/1-835 KRKRFFSDLAKNEKQSNLKD----SIRDFEANLVVCISNEKGKERNVREVDISKPG-FGF ENSRNOP00000047375/1-827 KRKRFF--LGAEKEKQNLKG----STREFETNLVVSISNEKGKERGVRAVEISKAG-FGF ENSP00000359869/1-913 KRKRMLSSSSEMNE-EFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECES ENSCPOP00000006715/1-882 GKNTMQSSDLEANESEKFLI-------KYNANPLKYKSPNWKKPSKAKEVQSNKKA--SP XP_004860172.1/1-900 KKKRMLPSDSEVNENEKSPIKKNIVREKSNANPLKYKSYTWKKQIKPRKFKSNEKL--AS :: : :: . . ::: * * : .. .: ENSMUSP00000110519/1-835 PFETNYPEDSGVDVRD-LNDLITKLFSPVLLETHCIENGLEWHEYMKTYLLYPEKLWQGL ENSRNOP00000047375/1-827 PFETNYPEEGSVNVRD-LNDLITKLFSPLLFETHYIENGLDWHEYMETFLLDPEKSWQGL ENSP00000359869/1-913 SCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGL ENSCPOP00000006715/1-882 VSVANVLDDRSVGDTN-LQNLSENALRELLMALNYSADS---SEPMLPSKVYSQARWQGL XP_004860172.1/1-900 LLKANYLEKPSVDDTD-LQFLTKSTLRQFQLALKCSEGG---SKLGLPRRVYQQTVWQGL * . :. . *: * . . . : . : : : :** ENSMUSP00000110519/1-835 PNVGNTCYINVVLQSLCSIPLFINDLFNQGFPWIKAPKDDFNMLLMQLLVLKDIYNARFR ENSRNOP00000047375/1-827 PNVGNTCYINVVLQSLCSIPLFVNDLFNQGFPWIKPPKDDFNMRLMQLLVLKDIYNARTR ENSP00000359869/1-913 PNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIK ENSCPOP00000006715/1-882 PNLGNTCYINAVLQSLCSIPLFVNDVLNQRFPWARICHDIFCLCMALLLTMKDVFNMSIK XP_004860172.1/1-900 PNLGNTCYINAVLQSLCSIPLFVNDVLNQGFPWGRISHDIFSLCVALLLTMKDIFNMRIK **:*****:*.***** *** * :*::** *** : : : : : ** :** :* : ENSMUSP00000110519/1-835 QKLLIGITKALPIFGEIFAVDRQNDAHEFLSLCLVQLKETFQRVTMMWQSENDSGDFYLL ENSRNOP00000047375/1-827 QKLLIGITKALPIFGEVFAADRQNDAHEFLSLCLVQLKETVQRVNMMWQSENESGDYYLL ENSP00000359869/1-913 EMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFP ENSCPOP00000006715/1-882 EKLLVTIKKTLSLVAEIFSMDAQNDAHEFLSFCLDQMKDGFEMSSIFGRSEYQS----LP XP_004860172.1/1-900 EKLLVTIIKAISVVAEIFPMDAQNDAHEFLSYCLGQMKEALQKPNVVLDSENEFQEENSP : **: : *::. .*:* : ********: ** *:*: .: . . .: : ENSMUSP00000110519/1-835 KDIFADYATINKMPVCPVTNNFEFELLSSIFCKACGLTLFKGEPSRYLSINIPQGGKD-- ENSRNOP00000047375/1-827 REIFANYTSINRTPVCPVTNNFEFELLSSIFCKACGLTVFKREPSRYLSINIPQGMKDQN ENSP00000359869/1-913 KQVFAD-DPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHP ENSCPOP00000006715/1-882 QQAFSG-DSATGMTGCPVVTNFECELLRSIFCKACGQAVYKTEPNNYLSINLPQGKKTQS XP_004860172.1/1-900 QQVFAG-DSAAGVPDCPVMTNFECELLHSIFCKACGQAIYKTEPSNYLSINLLQGMRRRP :: *:. . *** .*** *** ** ***** .: * * ..*****: * : ENSMUSP00000110519/1-835 MSIQSTLDLFFSAEELEHRCEKCLYNKSVSFHRFGRLPRVIIVHLKRYHFNESWVMKKDE ENSRNOP00000047375/1-827 MSIQSSLDLFFRAEELEHRCERCLYNKSVALHKFGRLPRVIIVHLKRYSFSESRIMNKDE ENSP00000359869/1-913 SSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKND ENSCPOP00000006715/1-882 LSIQSTLDHFFATEELEYKCAECKHKRSDIVYKFSKLPRILIIHLKRYRFTEVLSLRKDD XP_004860172.1/1-900 LSIQSTFDHFFATEELEYKCENCKHKRSVVVHKFSRLPRVLIIHLKRYCFNEFLSLRKDD ****::* ** :****::* .* :: * .: *.:***::*:***** :.* :.*:: ENSMUSP00000110519/1-835 RPILVSKYLRLSCHCSKSTKPPPPLRPGEHVKNLDLLKPLEVLGSEILKLPFNSVRTSRS ENSRNOP00000047375/1-827 QHIVISKYLRLSCHCNKNTKPPQPLLPNEHVKNLDLLRPLEELGSEILKLSSNSGRTSRS ENSP00000359869/1-913 QEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATK--ES ENSCPOP00000006715/1-882 QAVTIPTYLDLSSHCNESTKLPVPLSRTAHIRNMRLLLAFQKLSFSIL-CSLSLLKSEAP XP_004860172.1/1-900 QAVTVNKYLDLSSHCKEDTKPPVPLSKNAHIRDLQLLKLFQKLSLTVI-CSLSSVKS-KS : : : .** :*.**.:.*: * ** .: :: ** :. : : . : . ENSMUSP00000110519/1-835 KGFETINITSNRESEAQSGKRVSEVLSGKVQQENSGK------------GDTAHIVGSEL ENSRNOP00000047375/1-827 KVFPTVNIRSDKELEVQNGKRVSEVSSGSAQQEDPGK--------------GANVVRSEL ENSP00000359869/1-913 KDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPL ENSCPOP00000006715/1-882 KNSRPKRDKSGKGSDSQKPQRFLKG--KTVQQQKVGK----READSACLESAVMPREQQL XP_004860172.1/1-900 KNSVAKRVKAGKKPEPQKSQHFLKGKRRAQQQKDQGKPCM-RESESTCLGDGASVEKKQL * . . :.: : :. : . : **: ** . . * ENSMUSP00000110519/1-835 TK-------------------------------------ETEKLKKHEEEHRPSDLDSGS ENSRNOP00000047375/1-827 TN-------------------------------------ETETI-KHEKEYVLSDLDSGS ENSP00000359869/1-913 AHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKF--VAFDR ENSCPOP00000006715/1-882 ADSLMNLEDPYLPLFSRYSGTPFSSSDTCLTETQVQAMPENRKVKKSGKTNTFAESDFVS XP_004860172.1/1-900 AISVMNLEDTSLPLSYRYADKPARRPDT---EAQFPGVPEHPKLKKSKKSNRFAESDFDS : * . * : ENSMUSP00000110519/1-835 IREAQK-----------------YQQAEKCNEGRSDKQISLEALTQSRPKPISQEQTENL ENSRNOP00000047375/1-827 ISE---------------------ERSQKCQEAEKCN---KEALPQSCPKPSSQEQTENL ENSP00000359869/1-913 IINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNL ENSCPOP00000006715/1-882 VSETTGDFSKDKKTRVTGKSRKVTKQNKGYDERGIHKDTPQHTLPEGIPKPDAQKHQVNV XP_004860172.1/1-900 VSQTTEDFSKNKKARVSERSQTVAEPIDHPDGMEIHKGDLQQILPEGFPMPDAQEHRMNL : : : . : : . *.:. * * :* : *: ENSMUSP00000110519/1-835 GKTTLSHTQDSSQSSQSSSDSSKSSRCSDDLDKKAKPTRKVDPTKLNKKEDNVYRLVNII ENSRNOP00000047375/1-827 GKPAVSHTQNGSLSSQGSSDSSKSPGCNDVF-DKAKPTSKVEPQKLNQKEDNIYRLVSII ENSP00000359869/1-913 LRPTKLNLQKSNRNSLLALGSNKNPRNKDIL-DKIKSKAK-ETKRNDDKGDHTYRLISVV ENSCPOP00000006715/1-882 RGQTELNLQKA------------KPGNKDSSRKKTKSKISEPEEKVDNINPHTYRLIGII XP_004860172.1/1-900 RGCKELNPQKA------------NPGNKDILVKKTESRTQKPGKKADGKGPHTYRLIGII : *.. .. .* .* :. . : : : ***:.:: ENSMUSP00000110519/1-835 NHIGNSPNGGHYINDAFDFKRQSWFTYSDLHVTRTQEDFVYRGRSSTGYVFFYMHNDIFE ENSRNOP00000047375/1-827 NHIGNSPNGGHYINDAFDFRKQSWFTYSDLQVTGIQEDLVYKARLSTGYVFFYMHNDIFE ENSP00000359869/1-913 SHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFE ENSCPOP00000006715/1-882 SHLGSTLNSGHYITDAYDFTKQAWSTYNDLLVSSISESQVKKDRVSSGYIFFYMHNEIFE XP_004860172.1/1-900 SHLGNSHNSGHYISDVYDFKKQVWFTYNDLLVSRISESLVQKARLCTGYIFFYMHNEIFE .*:*.: :.**** *.:** :* * **.*: * .* : . * .:**:******:*** ENSMUSP00000110519/1-835 ELLAKETQSTSTSKG------------- ENSRNOP00000047375/1-827 ELLAKEAWSTSTSKG------------- ENSP00000359869/1-913 EMLKREENAQLNSKEVEETLQKE----- ENSCPOP00000006715/1-882 ELVLRLMTTQSKSKAKSRSKSEA----- XP_004860172.1/1-900 ELLLRIKTSQSQFKCEPKSRSTKARKRS *:: : : *