CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000006650/1-881 ---------MANGESIVRIPPYHYIHVLDQNSNVSRVEIGPKTYIRQDNERILFSPSPMV XP_004856196.1/1-901 MLARQLGVTMATEESIIRIPPYHYIHVLDQNSNVSHVEVGPKTYIRQDNERVLFAPVPMV ENSP00000349977/1-893 ---------MATEEFIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPMRMV ENSMUSP00000127250/1-870 MLGRGLGFTMATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMV ENSRNOP00000027360/1-861 ---------MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMV **. * *:******************:**:************:**:* ** ENSCPOP00000006650/1-881 TVPPRHYCVVANPVCRDGQGSVLLDVTGQVRLRHGDQEIRLAQDPFPLYPGEVLEKASTP XP_004856196.1/1-901 MVPPRHYCTVANPVCRDAQGTVLLDTTGQVRLRHADQEIRLAQDPFPLYPGEVLEKAITP ENSP00000349977/1-893 TVPPRHYCTVANPVSRDAQGLVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITP ENSMUSP00000127250/1-870 TVPPRHYCIVANPVSRDAQSSVLFDVTGQVRLRHADQEIRLAQDPFPLYPGELLEKDITP ENSRNOP00000027360/1-861 TVPPRHYCIVANPVSRDTQSSVLFDITGQVRLRHADQEIRLAQDPFPLYPGEVLEKDITP ******* *****.** *. **:* ********.* ***************:*** ** ENSCPOP00000006650/1-881 LQVVLPNTALHLKALLDFVHKNGDKVVAGDEWLFEGPGTYIPQKEVKVVEIIQATVIKPN XP_004856196.1/1-901 LQVVLPNTALHLKALLDFVDRNGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATVIKPN ENSP00000349977/1-893 LQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQN ENSMUSP00000127250/1-870 LQVVLPNTALHLKALLDFEDKNGDKVMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIKQN ENSRNOP00000027360/1-861 LQVVLPNTALHLKALLDFEDKNGDKVMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIKQN ****************** .::****:***************:***:********:*: * ENSCPOP00000006650/1-881 QALRLRARKECWDRDGKERVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRA XP_004856196.1/1-901 QALRLRARKECWDRDGKERVTGEEWLVRSVGAYLPGVFEEVLDLVDAVTLTEKTALHLQA ENSP00000349977/1-893 QALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRA ENSMUSP00000127250/1-870 QALRLRARKECFDRDGKERVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRA ENSRNOP00000027360/1-861 QALRLRARKECFDREGKGRVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRA ***********:**:** ********* :******.************ *********:* ENSCPOP00000006650/1-881 RQNFQDFRGVARRTGEEWLVTVRDTAAHVPDVYEEVLGVVPITTLGPRHYCVVLDPVGPD XP_004856196.1/1-901 LQNFQDLQGVARRTGEEWLVTVRDTAAHVPDVHEEVLGVVPITTLGPRHYCVVLDPVGPD ENSP00000349977/1-893 RRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPD ENSMUSP00000127250/1-870 RQNFKDLRGVAHRTGEEWLVTVQDTEAHVPDVYEEVLGVVPITTLGPRHYCVILDPMGPD ENSRNOP00000027360/1-861 LQNFRDLRGVLHRTGEEWLVTVQDTEAHVPDVYEEVLGVVPITTLGPRHYCVILDPMGPD :**:*::** :**********:** ******:**************::***:***:*** ENSCPOP00000006650/1-881 GKNQLGQKRVIKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQS---------RPH XP_004856196.1/1-901 GKNQLGQKRVIKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQALEDGEEAKEGPH ENSP00000349977/1-893 GKNQLGQKRVVKGEKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSH ENSMUSP00000127250/1-870 GKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQPLEEGEGEEKVAH ENSRNOP00000027360/1-861 GKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQPLEEGESEEKVSH **********:************:**:****************:***. .* ENSCPOP00000006650/1-881 QAGDHWLIRGPLEYVPSAKVEVVEVRQAIPLDENEGIYVQDIKTGKVRAVIGSTYMLSQD XP_004856196.1/1-901 QAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVVGSTYMLTQD ENSP00000349977/1-893 QAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQD ENSMUSP00000127250/1-870 QAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQD ENSRNOP00000027360/1-861 QAGDCWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQD **** ******************* *******:********:********:******:** ENSCPOP00000006650/1-881 EVLWEKELPPGVEELLNKAQDPLADRGMKDTTSIRQPSTPRNKTRVVSYRVPHNAAVQVY XP_004856196.1/1-901 EVLWEKELPPGVEELLSSAQDPLADRGLKDAAKP-HPPGARNKTRVVSYRVPHNAAVQVY ENSP00000349977/1-893 EVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPLAPRNKTRVVSYRVPHNAAVQVY ENSMUSP00000127250/1-870 EVLWEKELPSGVEELLNLGHDPLADRGQKGTAKVLQPSAARNKTRVVSYRVPHNAAVQVY ENSRNOP00000027360/1-861 EVLWEKELPSGVEELLNLGHDPLADRGQKGTAKPLQPSAPRNKTRVVSYRVPHNAAVQVY *********.******. .:******* *.::. :* .******************** ENSCPOP00000006650/1-881 DYRAKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRVLCLLLGPDFFTDVITIET XP_004856196.1/1-901 DYRAKHARVIFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIET ENSP00000349977/1-893 DYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIET ENSMUSP00000127250/1-870 DYRAKRARVVFGPELVSLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIET ENSRNOP00000027360/1-861 DYRAKRARVVFGPELVTLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIET *** *:***:******:*.**********************.****************** ENSCPOP00000006650/1-881 ADHARLQLQLAYNWHFELSNRNDPQEVAKLFSVPDFVGDACKAIASRVRGAVASVTFDDF XP_004856196.1/1-901 ADHARLQLQLAYNWHFELSDPNDPQEAAKLFSVPDFVGDACKAIASRVRGAVASVSFDDF ENSP00000349977/1-893 ADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDF ENSMUSP00000127250/1-870 ADHARLQLQLAYNWHFELKNRNDPEETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDF ENSRNOP00000027360/1-861 ADHARLQLQLAYNWHFELKNRNDPAEAAKLFSVPDFVGDACKAIASRVRGAVASVTFDDF *****************:.: :** *.****************************:**** ENSCPOP00000006650/1-881 HKNSARIIRAAVFGFEPSETKGSDGLALPKARDRAFFPQNGLVVSSVDVQSVEPVDQRTR XP_004856196.1/1-901 HKNSARVIRTAVFGFETSETKGPGGVALPRPRDQAFFPQNGLVVSSVDVQSVEPVDQRTR ENSP00000349977/1-893 HKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTR ENSMUSP00000127250/1-870 HKNSARIIRMAVFGFEMSEDAGPDGALLPRARDRAVFPQNGLVVSSVDVQSVEPVDQRTR ENSRNOP00000027360/1-861 HKNSARIIRMAVFGFEMSEDTGPDGTLLPKARDQAVFPQNGLVVSSVDVQSVEPVDQRTR ******:** ****** ** *..* **:.**:*.************************ ENSCPOP00000006650/1-881 DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKQLLELEA XP_004856196.1/1-901 DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLDRQKILDQSEAEKARKQLLELEA ENSP00000349977/1-893 DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA ENSMUSP00000127250/1-870 DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA ENSRNOP00000027360/1-861 DALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEA *************************************:***************:****** ENSCPOP00000006650/1-881 MSMAVESTGTAKAEAESRAEAARIEGEGSVLQARLKAQALAIETEAELQRIQKVREQELV XP_004856196.1/1-901 MSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIEMEAELQRVQKVREQELI ENSP00000349977/1-893 LSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELV ENSMUSP00000127250/1-870 MSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELI ENSRNOP00000027360/1-861 MSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELI :********.***********************:********* ****:*::**** **: ENSCPOP00000006650/1-881 YARAQLELEVSKAQQLAEVEVKKFTQMTEALGPSTIRDLAVAGPEMQVKLLQSLGLKSTL XP_004856196.1/1-901 FARAQLELEVSKAQQLAEVEVKKFKQMTEALGPSTIRDLAVAGPEMQVKLLQSLGLKSTL ENSP00000349977/1-893 YARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTL ENSMUSP00000127250/1-870 YSRAQLELEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTL ENSRNOP00000027360/1-861 YARAQLELEVSKAQQLANVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTL ::***************:**.***.:****:**.************************** ENSCPOP00000006650/1-881 ITDGSTPINLFNTAFGLLGLGADGQPPTRKAAGG-TPLESASFQAAPTLQATGGNHIVPF XP_004856196.1/1-901 ITDGSTPINLFNTAYGLLGLGADGQPAARKAAGGALP-EGLSLQP-PSPQGPGGNYVAPS ENSP00000349977/1-893 ITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPV ENSMUSP00000127250/1-870 ITDGSSPINLFNTAFGLLGLGSDGQPPVQK------------------------------ ENSRNOP00000027360/1-861 ITDGSSPINLFSTAFGLLGLGSDGQPPAQK------------------------------ *****:*****.**:****:*.:*** :: ENSCPOP00000006650/1-881 ---- XP_004856196.1/1-901 LGPR ENSP00000349977/1-893 LR-- ENSMUSP00000127250/1-870 ---- ENSRNOP00000027360/1-861 ----