CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000030571/1-1577 ------------MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT ENSRNOP00000060321/1-1560 ------------MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT ENSP00000362762/1-1585 MENTGWMGKGHRMTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT ENSCPOP00000006490/1-1553 ------------MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT XP_004850885.1/1-1551 ------------MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQDLFPT ************************************************ ENSMUSP00000030571/1-1577 IASGCSWTLENPDPTKYSLYLRFNRQEQVCTHFAPRLLPLDHYLVNFTCLRPGPEEATAR ENSRNOP00000060321/1-1560 IASGCSWTLENPDPTKYSLYLRFNRQEQVCTHFAPRLLPLDHYLVNFTCLRPGPEEATAR ENSP00000362762/1-1585 IASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAVAQ ENSCPOP00000006490/1-1553 IASGCSWTLENPDPTKYSLYLRFNRQEQVCTHFAPRLLPLDHYLANFTCLRPSPEEAGAQ XP_004850885.1/1-1551 IASGCSWTLENPDPTKYSLYLRFNRQEQVCAHFAPRLLPLDHYLVNFTCLRPSPEEAGAQ ******************************:*************.*******.**** *: ENSMUSP00000030571/1-1577 AESEVGRPEEEEEEAAAAASGLELCGGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAA ENSRNOP00000060321/1-1560 AESEVGRPEEEAEAEAAAT-GLELCGGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAA ENSP00000362762/1-1585 AESEVGRPEEEEAEAAA---GLELCSGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAA ENSCPOP00000006490/1-1553 AEPAVGQTGEEEAAAAA---GLELCGGSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPAA XP_004850885.1/1-1551 TESEVGQTEEEEAAAA----GLELCSSSGPFTFLHFDKNFVQLCLSAEPSEAPRLLAPSA :*. **:. ** * *****..*******************************:* ENSMUSP00000030571/1-1577 LAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGANPATTT ENSRNOP00000060321/1-1560 LAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGASPATTT ENSP00000362762/1-1585 LAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGSTTTT ENSCPOP00000006490/1-1553 LAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGASPATTP XP_004850885.1/1-1551 LAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGEAGAGPATTF ******************************************************..:** ENSMUSP00000030571/1-1577 SPGPPVAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSA ENSRNOP00000060321/1-1560 PPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSA ENSP00000362762/1-1585 SPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSA ENSCPOP00000006490/1-1553 -PGPPAAHTLSNALVPGVPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSA XP_004850885.1/1-1551 -PGPPGDHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEEPKVKTQWPRSA **** ********** ****************************************** ENSMUSP00000030571/1-1577 DEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNN ENSRNOP00000060321/1-1560 DEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNN ENSP00000362762/1-1585 DEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNN ENSCPOP00000006490/1-1553 DEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNN XP_004850885.1/1-1551 DEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNN ************************************************************ ENSMUSP00000030571/1-1577 SATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP ENSRNOP00000060321/1-1560 SATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP ENSP00000362762/1-1585 SATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP ENSCPOP00000006490/1-1553 SATCPVNGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP XP_004850885.1/1-1551 SATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGPELQTKLCSMAACP ******:***************************************************** ENSMUSP00000030571/1-1577 VEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPAWATCAGALTDTRECSNLDCPATDGK ENSRNOP00000060321/1-1560 VEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPAWATCAGALTDTRECSNFDCPATDGK ENSP00000362762/1-1585 VEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSK ENSCPOP00000006490/1-1553 VEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDGK XP_004850885.1/1-1551 VEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPSWATCTGALTDTRECNNLECPATDGK ***************:******************:****:*********.*::*****.* ENSMUSP00000030571/1-1577 WGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDE ENSRNOP00000060321/1-1560 WGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDE ENSP00000362762/1-1585 WGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDE ENSCPOP00000006490/1-1553 WGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDE XP_004850885.1/1-1551 WGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEEVKPCSEKRCPAFHEMCRDE ***************************:******************************** ENSMUSP00000030571/1-1577 YVMLMTWKRAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYL ENSRNOP00000060321/1-1560 YVMLMTWKRAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYL ENSP00000362762/1-1585 YVMLMTWKKAAAGEIIYNKCPPNASGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYL ENSCPOP00000006490/1-1553 YVMLMTWKKAAAGEIIYNKCPPNATGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYL XP_004850885.1/1-1551 YVMLMTWKKAAAGEIIYNKCPPNATGSASRRCLLSAQGVAYWGLPSFARCISHEYRYLYL ********:***************:*********************************** ENSMUSP00000030571/1-1577 SLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVP ENSRNOP00000060321/1-1560 SLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVP ENSP00000362762/1-1585 SLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVP ENSCPOP00000006490/1-1553 SLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVP XP_004850885.1/1-1551 SLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSGDLLFSVDILRNVTDTFKRATYVP ************************************************************ ENSMUSP00000030571/1-1577 SADDVQRFFQVVSFMVDSENKDKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLI ENSRNOP00000060321/1-1560 SADDVQRFFQVVSFMVDSENKDKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLI ENSP00000362762/1-1585 SADDVQRFFQVVSFMVDAENKEKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLI ENSCPOP00000006490/1-1553 SADDVQRFFQVVSFMVDEENKDKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLI XP_004850885.1/1-1551 SADDVQRFFQVVSFMVDEENKDKWDDAQQVSPGSVHLLRVVEDFIHLVGDALKAFQSSLI ***************** ***:************************************** ENSMUSP00000030571/1-1577 VTDNLVISIQREPISAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATP ENSRNOP00000060321/1-1560 VTDNLVISIQREPISAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATP ENSP00000362762/1-1585 VTDNLVISIQREPVSAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGKPATS ENSCPOP00000006490/1-1553 VTDNLVISIQREPISAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPANPSTA XP_004850885.1/1-1551 VTDNLVISIQREPISAVSSDITFPMRGRRGMKDWVRHSEDRLFLPKEVLSLSSPGNPAAP *************:****************************************.:*::. ENSMUSP00000030571/1-1577 GAATAGSPGRGRGPGTVPPGPGHAHQRLLPADPEESSSYFVIGAVLYRTLGLILPPPRPP ENSRNOP00000060321/1-1560 GAATAGSPGRGRGPGTVPPGPGPAHQRLLPADPEESSSYFVIGAVLYRTLGLILPPPRPP ENSP00000362762/1-1585 GA--AGSPGRGRGPGTVPPGPGHSHQRLLPADPDE-SSYFVIGAVLYRTLGLILPPPRPP ENSCPOP00000006490/1-1553 GA--AGNPGKVRGPGTVPPGPGHSHQRLLPADPDD-SSYFVIGAVLYRTLGLILPPPRPP XP_004850885.1/1-1551 GA--AGTPGKGRGPGTVPPGPGHSHQRLLPADPDD-SSYFVIGAVLYRTLGLILPPPRPP ** **.**: *********** :*********:: ************************ ENSMUSP00000030571/1-1577 LAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADTNSGDWNTESC ENSRNOP00000060321/1-1560 LAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASLGDWNTESC ENSP00000362762/1-1585 LAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTENC ENSCPOP00000006490/1-1553 LAVTSRVMTVTVRPPTQPPSEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTESC XP_004850885.1/1-1551 LAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRADASSGDWDTESC *******************:*****************************:. ***:**.* ENSMUSP00000030571/1-1577 QTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGAPSVPLVIGCAVSCMALLTLLAIY ENSRNOP00000060321/1-1560 QTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGAPSVPLVIGCAVSCMALLTLLAIY ENSP00000362762/1-1585 QTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLVIGCAVSCMALLTLLAIY ENSCPOP00000006490/1-1553 QTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGAPSVPLVIGCAVSCMALLTLLAIY XP_004850885.1/1-1551 QTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGAPSVPLVIGCAVSCMALLTLLAIY ************************************:*********************** ENSMUSP00000030571/1-1577 AAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWV ENSRNOP00000060321/1-1560 AAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWV ENSP00000362762/1-1585 AAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWV ENSCPOP00000006490/1-1553 AAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWV XP_004850885.1/1-1551 AAFWRFIKSERSIILLNFCLSILASNILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWV ************************************************************ ENSMUSP00000030571/1-1577 LTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEG ENSRNOP00000060321/1-1560 LTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEG ENSP00000362762/1-1585 LTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEG ENSCPOP00000006490/1-1553 LTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEG XP_004850885.1/1-1551 LTEAWQSYLAVIGRMRTRLVRKRFLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEG ************************************************************ ENSMUSP00000030571/1-1577 GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGVSDKSKKQRAGSERCPWASLLLPCSAC ENSRNOP00000060321/1-1560 GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGVSDKSKKQRAGSERCPWASLLLPCSAC ENSP00000362762/1-1585 GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSAC ENSCPOP00000006490/1-1553 GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSAC XP_004850885.1/1-1551 GLLYAFVGPAAVIVLVNMLIGIIVFNKLMARDGISDKSKKQRAGSERCPWASLLLPCSAC *********************************:************************** ENSMUSP00000030571/1-1577 GAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQ ENSRNOP00000060321/1-1560 GAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQ ENSP00000362762/1-1585 GAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQ ENSCPOP00000006490/1-1553 GAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQ XP_004850885.1/1-1551 GAVPSPLLSSASARNAMASLWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQ ************************************************************ ENSMUSP00000030571/1-1577 GFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTV ENSRNOP00000060321/1-1560 GFVITAVHCFLRREVQDVVKCQMGVCRTDESEDSPDSCKNGQLQILSDFEKDVDLACQTV ENSP00000362762/1-1585 GFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTV ENSCPOP00000006490/1-1553 GFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTV XP_004850885.1/1-1551 GFVITAVHCFLRREVQDVVKCQMGVCRADESEDSPDSCKNGQLQILSDFEKDVDLACQTV ***************************:******************************** ENSMUSP00000030571/1-1577 LFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGE ENSRNOP00000060321/1-1560 LFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGE ENSP00000362762/1-1585 LFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGSLSFSPLPGNILVPMAASPGLGE ENSCPOP00000006490/1-1553 LFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGE XP_004850885.1/1-1551 LFKEVNTCNPSTITGTLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGE *************************************.********************** ENSMUSP00000030571/1-1577 PPPPQETNPVYMCGEGGLRQLDLTWIRQSEPGSEGDYMVLPRRTLSLQPGGGGTAGEEAP ENSRNOP00000060321/1-1560 PPPPQETNPVYMCGEGGLRQLDLTWLRPSEPGSEGDYMVLPRRTLSLQPGGGGTGGEEAP ENSP00000362762/1-1585 PPPPQEANPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTLSLQPGGGGGGGEDAP ENSCPOP00000006490/1-1553 PPPPQETNPVYMCGEGGLRQLDLTWLRPTEPGSEGDYMVLPRRTMSLQPGSGGGGGEDAP XP_004850885.1/1-1551 PPPPQETNPVYMCGEGGLRQLDLTWLRPTEAGSEGDYMVLPRRTMSLQPGSGGGGGEDAP ******:******************:* :*.*************:*****.** .**:** ENSMUSP00000030571/1-1577 RARPEGTPRRAAKTVAHTEGYPSFLSVEHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQ ENSRNOP00000060321/1-1560 RARPEGTPRRAAKTVAHTEGYPSFLSVEHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQ ENSP00000362762/1-1585 RARPEGTPRRAAKTVAHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQ ENSCPOP00000006490/1-1553 RARPEGTPRRAAKALTHTEGYPSFLSVEHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQ XP_004850885.1/1-1551 RARPEGTPRRAAKALTHTEGYPSFLSVDHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQ *************:::***********:******************************** ENSMUSP00000030571/1-1577 VPEPGERSRTMPRTVPGSTMKLGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHT ENSRNOP00000060321/1-1560 VPEPGERSRTMPRTVPGSTMKLGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHT ENSP00000362762/1-1585 VPEPGERSRTMPRTVPGSTMKMGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHT ENSCPOP00000006490/1-1553 VPEPGERSRTMPRTVPGSTMKLGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHT XP_004850885.1/1-1551 VPEPGERSRTMPRTVPGSTMKLGSLERKKLRYSDLDFE-VMHTRKRHSELYHELNQKFHT *********************:**************** ********************* ENSMUSP00000030571/1-1577 FDRYRSQSSAKVR---WMRGCNRLALLLSQEKPSPPGGRPGLSQHRRHQSWSTFKSMTLG ENSRNOP00000060321/1-1560 FDRYRSQSSAK-------------------EKPSPPGGRPGLSQHRRHQSWSTFKSMTLG ENSP00000362762/1-1585 FDRYRSQSTAKREKRWSVSSGGAAERSVCTDKPS-PGERPSLSQHRRHQSWSTFKSMTLG ENSCPOP00000006490/1-1553 FDRYHSQSAAK-------------------EKPS-PGERPGLSQHRRHQSWSTFKSMTLG XP_004850885.1/1-1551 FDRYHSQSAAK-------------------EKPS-PGERPSLSQHRRHQSWSTFKSMTLG ****:***:** :*** ** **.******************* ENSMUSP00000030571/1-1577 SLPPKPRERLALHRTAAWEPTEPPDGDFQTEV ENSRNOP00000060321/1-1560 SLPPKPRERLALHRTAAWEPTEPPDGDFQTEV ENSP00000362762/1-1585 SLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV ENSCPOP00000006490/1-1553 SLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV XP_004850885.1/1-1551 SLPPKPRERLTLHRAAAWEPTEPPDGDFQTEV **********:***:*****************