CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000006466/1-905 MATSTTSPSSPLQAEDLLSETSEPPGLNQVSSEVTSQLYTSLHLSRQAEATARAQLYLGS XP_004857523.1/1-908 MATSTTSPSSPLRAEDLLSESSEPPGLNQVSSEVTSQLYTSLHLSRQAEATARAQLYLAS ENSP00000369614/1-925 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS ENSMUSP00000090651/1-887 MATAAPSPSSPLRPEDLLSDSSEPPGLNQVSSEVTSQLYTSLHLSRQAEATARAQLYLAP ENSRNOP00000011185/1-897 MATAAPSPNSPLRPEDLLTDSSEPPGLNQVSSEVTSQLYTSLHLSRQAEATARAQLYLAS ***:: **.*** .****:::******************:**:*************** . ENSCPOP00000006466/1-905 TSPPPHEALDGLAQELSRSLSVGLENNLKKKDGSKHIFEMESVRGQLQTMLQTSRDAAYR XP_004857523.1/1-908 TSPPPHEALDSLAQELSRSLSVGLENNLKKKDGFKHIFEMESVRGQLQTMLQTSHDAAYR ENSP00000369614/1-925 TS-PPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYR ENSMUSP00000090651/1-887 TSSPPNEGLDSLAQELSRSLSVGLENNLKKKDGSKHIFEMESVRGQLQTMLHTSRDTAYR ENSRNOP00000011185/1-897 TSSPPNEGIDSLAQELSRSLSVGLENNLKKKDGSKHIFEMESVRGQLQTMLHTSRDMAYR ** **:*.:*.:*************:******* *****************:**:* *** ENSCPOP00000006466/1-905 DPLTAGAGLEKREEESFDSDSTATLLNTRFLQDLSPSSSAQALEELFPRYTSLRPGLPIN XP_004857523.1/1-908 DPLTAGAGIEKREEESFDSDSTATLLNTQLLQDISPPSSAQALEELFPRYTSLRPGLPVN ENSP00000369614/1-925 DPLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLN ENSMUSP00000090651/1-887 ------TGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAPALEELFPRYTSLRPGPPTN ENSRNOP00000011185/1-897 ------TGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPTN :* *:***:*************: ***:**.*** *************** * * ENSCPOP00000006466/1-905 PPDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDIMIEQLDKTL XP_004857523.1/1-908 PPDFQRLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDIMIEQLDKTL ENSP00000369614/1-925 PPDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTL ENSMUSP00000090651/1-887 PPDFQGLRDALDAELTRRKHCERHIQSLQTRVLELQQQLAVAVAADHKKDLMIEQLDKTL ENSRNOP00000011185/1-897 PPDCQGLRDALDSELTRRKHCERHIQSLQTRVLELQQQLAVAVAADHKKDLMIEQLDKTL *** * ******:* *******************************:*** ********* ENSCPOP00000006466/1-905 ARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALSREQEGA XP_004857523.1/1-908 ARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMETLNREQEGA ENSP00000369614/1-925 ARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESA ENSMUSP00000090651/1-887 ARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALSREQEGA ENSRNOP00000011185/1-897 ARVVEGWNRHEAERTEVLRGLQEERQAAELTRSKQQETVTRLEQSLSEAMEALNREQEST ************************:**************************:*.****.: ENSCPOP00000006466/1-905 RLQQREREALEAERQALTLSLEAEQQRNRALQEERDEARAVQLSERRKLESLQVALEEER XP_004857523.1/1-908 RLQQREREVLEEERQALTLSLEVEQQRSHALQEERDEARAGQLSEHRKLETLQVALEEER ENSP00000369614/1-925 RLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEER ENSMUSP00000090651/1-887 RLQQREKEALEEERQALTLRLEVEQQQCRTLQEERDEARAGQLSEHRKLEALQVALQEER ENSRNOP00000011185/1-897 RLQQREREALEEERQALAMRLEVEQQQCQALQQERDEAKAGQLSEHRRLEALQVALQEER ******:*.** *****:: **.***: .**:*** *:* ****:*.**:*:.**:*** ENSCPOP00000006466/1-905 QARAQQEHQLKERYQALQEEGQAQLEREKGNSQREAQAAREAQQQLALVQSEVRRLEEEL XP_004857523.1/1-908 QAWAQQEHQLKERYQTLQGESQAQLEREKGNSQREAQAAREAQQELALVQSEVRRLEGEL ENSP00000369614/1-925 QTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGEL ENSMUSP00000090651/1-887 QAWIKQEHQLKERLQALQEEGQAQLEREKGNSQREAQAAWETQQQFALLQTEVRRLEGDL ENSRNOP00000011185/1-897 QAWVKQEQQLKERLQALQEEGQAQLEREKGTSQREAQAAREAQQQLALLQSEVRRLEGDL *: :**:****: *:** *.******** .******** *:*:::**:*:****** :* ENSCPOP00000006466/1-905 DTARRERDALQLEMSLVQARSESQRIQMESELAVQLEQQVAERLAQAQESSLRQTASLRE XP_004857523.1/1-908 DTARRERDALQLEMSLVQARFERQRIQMESELAVQLEQQVMERMAQAQESSLRQAASLRE ENSP00000369614/1-925 DTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLRE ENSMUSP00000090651/1-887 DTVRRERDALQLEMSLVQARYESQRIQMESELAVQLEQRVTERLAEAQENSLRQAASLRD ENSRNOP00000011185/1-897 DTVRRERDALQLEMSLVQARYESQRIQMESELAVQLEQRVTERLAEVQENSLRQAASLRD **.***************** * ****:**********:* **:*:.**.****:****: ENSCPOP00000006466/1-905 HHRKQLQDINGQHQQELATQLAQFKVEMAEREERQQQVAQDYELRLAREQARVRDLQSGN XP_004857523.1/1-908 HHRKQLQDLNGQHQQELATQLAQFKVEMAEREERQQQVAQDYELRLAREQARVRDLQSGN ENSP00000369614/1-925 HHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGN ENSMUSP00000090651/1-887 HHRKQLQELSGQHQQELAAQLAQFKVEMADREERQQQVAQDYELRLAREQARVRDLKSGN ENSRNOP00000011185/1-897 HHRKQLQELSGQHQQELAAQLAQFKVEMAEREERQQQVAQDYELRLAREQARVRDLKSGN *******::.********:**********:*********:************* :*:*** ENSCPOP00000006466/1-905 QQLEEQRVEMAERLQAMLQAHWEEVSRLLSTILPPPNPAVPPTGPPNSDPPELEKAERRT XP_004857523.1/1-908 KQLEEQRVELVERLQAMLQAHWDEVNQLLGTTLQPPNSPVPPTGPSSSDLPETEKGERRI ENSP00000369614/1-925 QQLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRV ENSMUSP00000090651/1-887 QQLEEQRAELVERLQAMLQAHWEEANQLLSTTLLPPNPQAPLAEPSSPGPLEPEKGERRT ENSRNOP00000011185/1-897 QQLEEQRVELVERLQAMLQAHWDEANQLLSTTLLPPNPQAPLAEPSSPGPLEPEKGERRI :******.*:.***********:*..:**.* * ***. .* : *.... * ** *** ENSCPOP00000006466/1-905 WTMPPVAVALKPVSQQSRE---AKDELRGMPLVDCSASPDLSLLLGPSFQSQHSFQPLEP XP_004857523.1/1-908 WTMPPVAVALKPALQQSREARDARDELPGVPPVDCSPSPDLSLLLGPSFLSQHSFQPLEP ENSP00000369614/1-925 WTMPPMAVALKPVLQQSRE---ARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEP ENSMUSP00000090651/1-887 WAMPPMAVALKPVLQQSRE---VKGDVPGAPSVLCSTSPDLSLLLGPPFQNQNSFQPLEP ENSRNOP00000011185/1-897 WAMPPMAVALKPVLQQGRE---GRADLPGAPSVLCSTSPDLSLLLGPSFQSQNSFQPLEP *:***:******. **.** : :: * * * **.*.********.* .*:******* ENSCPOP00000006466/1-905 KPDLTPPIAEDFPALGAFHPDHRAERPFPEEDPASERDGFLKQGLPPASQLEGLKNFLQQ XP_004857523.1/1-908 KPDLTPSIAEDFSALGAFQTDHRAERPFPEEDVGSEGDGFLKQGLPPASQLEGLKNFLQQ ENSP00000369614/1-925 KPDLTSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPA-QLEGLKNFLHQ ENSMUSP00000090651/1-887 KPDVTPPTAGPFSALEAFTDDHRAERPFPEEDPGSDGD----ARLPPASQLEGLKNFLQQ ENSRNOP00000011185/1-897 KPDVAPPAVGPFSALEAFTADHRAEHPFPEEDPGPEGDGPLKAGLPPASQLEGLKNFLQQ ***::.. . *.** ** *****:****** ..: : **** *********:* ENSCPOP00000006466/1-905 LLETVPQSGESPSADVLPAKCGPRTGPSWEEPSQVPRLPPPVHKTKVPLAMASSLFRVQE XP_004857523.1/1-908 LLETVPQNNESPSVDLLPPKYGPQTVPSWEEASQVPRLPPPVHKTKVPLAMASSCFRVHE ENSP00000369614/1-925 LLETVPQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPE ENSMUSP00000090651/1-887 LLETAPQSNGNPSADLLLPKAGSRAVSSWEEAPQVPRLPPPVHKTKVPLAMASSLFRVHG ENSRNOP00000011185/1-897 LLETAPQSNENPSVDLLAPKSGSRAVSSWEEAPQVPRLPPPVHKTKVPLAMASSLFRVHE ****.**.. .**.*:* .* *. : .****..****:**************** *** ENSCPOP00000006466/1-905 QPSSYSQGSGPSSGSPEKGADGLGSSRQLMEMSQLLRQYQAQGWGTLPAEDLLLYLKRLE XP_004857523.1/1-908 VPSSYSQGSGPSTGSPEKGADGLSSSRQLMEMSQLLRQYQARGWGTLSAEDLLLCLKKLE ENSP00000369614/1-925 PPSSHSQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLE ENSMUSP00000090651/1-887 LPSTNLQGSGLSTGSPEK--DGLN----LVDVSELLRLYQARGWGALPAEDLLLYLKRLE ENSRNOP00000011185/1-897 LPSSNLQGSGVSTGSPEKGTDGLSPPRQLMEVSELLRLYQARGWGALPAEDLLLYLKRLE **: **** *:****: *** *:::*:*** ***:***:*.****** **:** ENSCPOP00000006466/1-905 H----------------------SGTDGRGESVPRRNPDSRVGEISRKEIPSQAVPRRLA XP_004857523.1/1-908 H----------------------GGTDSRGENVPRRNPDSRLGEISRKEIPSQAVPRCLA ENSP00000369614/1-925 HSGYKPGRKEEGFSGWKLDYGEWSGTDGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLA ENSMUSP00000090651/1-887 H----------------------SGTDGQGELVPRRNTDSRLGETTRKEIPSQAVPRRLA ENSRNOP00000011185/1-897 H----------------------GGTDGQGELVPRRNTDSRLGEITRKEIPSQAVPRRLA * .***.:*: *****.***:** .*********** ** ENSCPOP00000006466/1-905 TAPKTEKPPARKKSSHLAPSSMRGRGGVWR XP_004857523.1/1-908 TAPKSDKPPARKKSSHPTPSSMRSRGGIWK ENSP00000369614/1-925 TAPKTEKPPARKKSGHPAPSSMRSRGGVWR ENSMUSP00000090651/1-887 SVPKTEK-PARKKSGHPGP-SMRSRGGIWR ENSRNOP00000011185/1-897 SAPKTEK-PARKKSGHPGP-SMRSRGGIWR :.**::* ******.* * ***.***:*: