CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000044231/1-745 --------------MHWVKILGVALGAAALLGLGIILGHFAIPKATSPLTSSTSDSQDLD ENSRNOP00000051719/1-745 --------------MHWAKILGVGIGAAALLGLGIILGHFAIPKATEPLASSVSDSQDLD ENSP00000344244/1-791 --------------MQWTKVLGLGLGAAALLGLGIILGHFAIPKKANSLA-----PQDLD ENSCPOP00000006249/1-756 IYKESPSRSPPGCRMQWVKLVGLGVGAAALLGLGIILGHFAIPKVAEQSASSTSGPQDLD XP_004852489.1/1-739 --------------MQWVKVVGLGVGAAALLGLGIILGHFAIPKGAEQPA-----PQDLD *:*.*::*:.:******************* :. : .**** ENSMUSP00000044231/1-745 LAILDSVMGQLDASRIRENLRELSKEPHVATSPRDEALVQLLLGRWKDTATGLDSAKTYE ENSRNOP00000051719/1-745 LAILDSVMGQLDASRIRENLRELSKEPHVATSARDEALVQLLLGRWKDSASGLDTAKTYE ENSP00000344244/1-791 LEILETVMGQLDAHRIRENLRELSREPHLASSPRDEDLVQLLLQRWKDPESGLDSAEAST ENSCPOP00000006249/1-756 REILETVMAQLDAGRIRENLLELSKEPHLATTPRDEDLVQLLLQRWKDPVSGLDTARTVE XP_004852489.1/1-739 LETLETLMKQLDASKIRENLRELSQQPHLASSPRDEALVQLLLQRWGDQVSGLDEARTVE *:::* **** :***** ***::**:*::.*** ****** ** * :*** *.: ENSMUSP00000044231/1-745 YRVLLSFPNAEQPNSVEVVGPNGTTFHSFQPFEKNLTGEQAGPNVLQPYAAYAPPGTPKG ENSRNOP00000051719/1-745 YTVLLSFPSTEQPNSVEVVGPNGTVFHSFQPFEKNLTGEQAEPNVLQPYAAYAPPGTPKG ENSP00000344244/1-791 YEVLLSFPSQEQPNVVDIVGPTGGIIHSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQG ENSCPOP00000006249/1-756 YEVLLSLPSSEQPNLVEVVGSNGSVQQSYLPKEEEVTGEQEGPDVVQPYAAYAPPGTPQG XP_004852489.1/1-739 YEVLLSFPSPEHPNLIEVVGPDGAVLHSYLPKEENVTGEQGGPDVVQPYAAYAPPGTPQG * ****:*. *:** :::**. * :* *:::**** *:*:********.***:* ENSMUSP00000044231/1-745 LLVYANQGSEEDFKELETQGINLEGTIALTRYGGVGRGAKAINAAKHGVVGVLVYTDPGD ENSRNOP00000051719/1-745 PLVYANRGSEDDFKKLEAEGINLKGTIALTRYGSVGRGAKAINAARHGVVGVLVYTDPGD ENSP00000344244/1-791 LLVYANRGAEEDFKELQTQGIKLEGTIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPAD ENSCPOP00000006249/1-756 LLVYANHGTEDDFKYLQDQGINLQGTIALTRYGVAGRGAKAVNGARHGVVGVLVYTDPGD XP_004852489.1/1-739 LLIYANHGTEDDFQYLFNQGINLQGTIALTRYGMAGRGAKAVNAAKYGVAGVLVYTDPGD *:***:*:*:**: * :**:*:********* .******:*.*::**.********.* ENSMUSP00000044231/1-745 INDGKSLPNETFPNSWRLPPSGVERGSYYEYFGDPLTPYLPAHPSSFRLDPHNTSGFPPI ENSRNOP00000051719/1-745 INDGKSLPNETFPNSWGLPPSGVERGSYYEYFGDPLTPYLPAHPVSFRLDPHNISGFPPI ENSP00000344244/1-791 INDGLSSPDETFPNSWYLPPSGVERGSYYEYFGDPLTPYLPAVPSSFRVDLANVSGFPPI ENSCPOP00000006249/1-756 INDGHSLPNETFPYSWGLPPSGVERGSYTGYFGDPVTPYLPARPSSFRLDWNSTSGFLPI XP_004852489.1/1-739 INDGRSFPNETFPYSWGLPPSGVERGSYYEYFGDPVTPYLPAHPSSFRLDSNNASGFPPI **** * *:**** ** *********** *****:****** * ***:* . *** ** ENSMUSP00000044231/1-745 PTQPIGFEDARDLLCNLTGTSAPAFWQGALGCEYKLGPGFEPNGSFPAGSEVKVSVHNRL ENSRNOP00000051719/1-745 PTQPIGFEDAKNLLCNLNGTSAPDSWQGALGCEYKLGPGFEPNGNFPAGSEVKVSVYNRL ENSP00000344244/1-791 PTQPIGFQDARDLLCNLNGTLAPATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRL ENSCPOP00000006249/1-756 PAQPIGFQHAEDLLCNLKGPQAPASWQGALSCVYHLGPGF-TGGKFPEDSQVKVSVHNRL XP_004852489.1/1-739 PAQPIGFRDAEDLLCNLRGLPAPVSWKGALHCEYHLGPGFKSGENFTADSQVKVSVHNRL *:*****..*.:***** * ** *:*** * *:***** .. .*. .*:*:***:*** ENSMUSP00000044231/1-745 ELRTSSNVLGIIQGAVE------------------------------------------- ENSRNOP00000051719/1-745 ELRNSSNVLGIIQGAVE------------------------------------------- ENSP00000344244/1-791 ELRNSSNVLGIIRGAVEPGEPSSCCLHPRPLLCSGCRCPHPALPLPPPSPAPPAHLSLSS ENSCPOP00000006249/1-756 VLRNSSNVLGFIRGAVE------------------------------------------- XP_004852489.1/1-739 ELRNSSNVLGIIRGAVE------------------------------------------- **.******:*:**** ENSMUSP00000044231/1-745 --------PDRYVIYGNHRDSWVHGAVDPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIF ENSRNOP00000051719/1-745 --------PDRYVIYGNHRDSWVHGAVDPSSGTAVLLEISRVLGTLLKKGTWRPRRSIIF ENSP00000344244/1-791 GSLPLFLWPDRYVLYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVF ENSCPOP00000006249/1-756 --------PDRYVVYGNHRDSWVHGAVDPSSGTAVLLEVSRVLGTLLKRGTWRPRRSIVL XP_004852489.1/1-739 --------PDRYVVYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVL *****:************************:*********:*********:: ENSMUSP00000044231/1-745 ASWGAEEFGLIGSTEFTEEFLSKLQERTVAYINVDISVFSNATLRAQGTPPVQSVIFSAT ENSRNOP00000051719/1-745 ASWGAEEFGLIGSTEFTEEFLSKLQERTVTYINVDISVFSNATLRAQGTPPVQSVIFSAT ENSP00000344244/1-791 ASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSAT ENSCPOP00000006249/1-756 ASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRGQGTPPVQNVIFSAA XP_004852489.1/1-739 ASWGAEEFGLIGSTEFTEEFFSKLQERTVAYINVDISVFANATLRGQGTPPVQSVIFSAA ********************:.*******:*********:***** *******.*:***: ENSMUSP00000044231/1-745 KEISAPGSSGLSIYDNWIRYTNRTSPVYGLVPSLGTLGAGSDYAAFVHFLGITSMDLAYT ENSRNOP00000051719/1-745 KEISAPGSSGLSIYDNWIRYTNRSSPVYGLVPSMGTLGAGSDYASFIHFLGITSMDLAYT ENSP00000344244/1-791 KEIRSPGPGDLSIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYT ENSCPOP00000006249/1-756 KEISSPGPSGLSIYDNWIRYNNRSSPVYGLIPSMGTLGAGSDYAPFIHFLGISSMDLAYT XP_004852489.1/1-739 KEISSPGSSGLSIYDNWIRYTNRSSPVYGLIPSMGTLGAGSDYAPFIHFLGISSMDIAYT *** :**...********** **:******:**:*:********.*:*****:***:*** ENSMUSP00000044231/1-745 YDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVS ENSRNOP00000051719/1-745 YDRSKTSARIYPTYHTAFDTFDYVEKFLDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVS ENSP00000344244/1-791 YDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVS ENSCPOP00000006249/1-756 YDQSKTSARIYPTYHTAFDTFKYVEKFLDPDFSSHQAVARMAGSVLLRLSDSLFLPLKVS XP_004852489.1/1-739 YDRSKTSARIYPTYHTAFDTLEYVEKFVDPDFSSHQAVARMAGSVLLRLSDSFFLPLKVS **:*****************:.**:**:**.********* ****:******:****:** ENSMUSP00000044231/1-745 DYSETLQSFLQAAQEALGTQLEKQNISLGPLVTAVANFKAAAASLGEHILTLQKSSPDPL ENSRNOP00000051719/1-745 DYSETLQSFLQAAQENLGALLESHNISLGPLVTAVEKFKAAAAALNQHILTLQKSSPDPL ENSP00000344244/1-791 DYSETLRSFLQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPL ENSCPOP00000006249/1-756 DYSETLRSFLQAAQQDLGALLVQHGISLGPLETAVENFEAAATDLGQRISDLQQDSPDSL XP_004852489.1/1-739 DYSETLRSFLQAAQQDLGALLEQHSISLGPLVTAVEKFEAAATALGQRISDLQKGSPDPL ******:*******: **: * .:.****** *** :*:* *: *.::* **:.***.* ENSMUSP00000044231/1-745 QVRMVNDQLMLLERAFLNPRAFPEERHYSHVLWAPNTASVDTFPGLANAYAKAQEINSGS ENSRNOP00000051719/1-745 QVRMVNDQLMLLERAFLNPRAFPEERYYSHVLWAPNTASVATFPGLANAYARAQEINSGA ENSP00000344244/1-791 QVRMLNDQLMLLERTFLNPRAFPEERYYSHVLWAPRTGSVVTFPGLSNACSRARDTASGS ENSCPOP00000006249/1-756 KVRMVNDQLMLLERAFLNPRAFPEERYYSHVLWAPRTSSVTTFPGLANACSKASTTDLGS XP_004852489.1/1-739 QVRMVNDQLMLLERTFLNPRAFPKERYYSHVLWAPRTGSVATFPGLANACSRA-NTPHGS :***:*********:********:**:********.*.** *****:** ::* *: ENSMUSP00000044231/1-745 EAWAEVQRQLSIVVTALEGAAATLVPVADL ENSRNOP00000051719/1-745 EAWAEVERQLSIAVMALEGAAATLQPVTDL ENSP00000344244/1-791 EAWAEVQRQLSIVVTALEGAAATLRPVADL ENSCPOP00000006249/1-756 AEWAEVHRQLSIVVAALEGAAATLRPVD-- XP_004852489.1/1-739 EEWAEVHRQLSIVVAALEGAAATLRPVDDL ****.*****.* ********* **