CLUSTAL W(1.81) multiple sequence alignment ENSP00000339115/1-1005 MEKQRALVAAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQ ENSMUSP00000086294/1-1005 MEAQQALVASKDGDMATLERLFEAGALRPDITDDLGAGLVHHATRAGHLDCVKFLVQRAK ENSRNOP00000036626/1-999 MEAQQALVASKDGDLATLERLFEAGGLRPDITDDLGAGLVHHATRAGHLDCVKFLVQTAK XP_004868583.1/1-1007 MEEQRALVAARAGDMATLERLLVAGSLGPGVRDTLGAGLVHHAARGGHLDCVCFLVRRAK ENSCPOP00000006191/1-1003 -MEEQALVAAKGGDVSTLERLLKAGSLGPGITDTLGAGLVHHAARAGHLDCIRFLVQQAK ::****:: **::*****: **.* *.: * *********:*.*****: ***: *: ENSP00000339115/1-1005 LPGNQRAHNGATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLV ENSMUSP00000086294/1-1005 LPGNQQAHNGATPVHDAAATGNLAELCWLVRDAGCGLQDQDASGVSPLHLAARFGHPALV ENSRNOP00000036626/1-999 LPSDQQAHNGATPVHDAAAMGNLAELCWLIRDGGCGLQDQDASGVSPLHLAARFGHPALV XP_004868583.1/1-1007 LPGNQRAQNGATPAHDAAAAGHLEELRWLLRNGGCGLQDRDASGISPLHLAARFGHPALV ENSCPOP00000006191/1-1003 LPGNQRAHNGATPAHDAAATGHLAELCWLVLNGGCGLQDQDASGVSTLHLAARFGHPALV **.:*:*:*****.***** * * ** **: :.******:****:*.**********.** ENSP00000339115/1-1005 EWLLHEGHSATLETREGARPLHHAAVSGDLTCLKLLTAAHGSSVNRRTRSGASPLYLACQ ENSMUSP00000086294/1-1005 EWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHSSGVNQRTCSGASPLYLACQ ENSRNOP00000036626/1-999 EWLLREGHAATLETLEGALPLHHAAVSGDLTCLKLLTAAHSSGVNQRTCSGASPLYLACQ XP_004868583.1/1-1007 EWLLQEGHAATLETLEGALPLHQAAVSGDLTCLKLLAAAHPRGVNRQTRSGASPLYLACQ ENSCPOP00000006191/1-1003 EWLLQEGHAATLETLEGALPLHHAAVSGDLTCLKLLVAAHSGCINRRTRSGASPLYLACQ ****:***:***** *** ***:*************.*** :*::* *********** ENSP00000339115/1-1005 EGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTFTDIGLTARDNEGA ENSMUSP00000086294/1-1005 EGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAAHGHYSLVVWLVTFTDIGLTARDNEGA ENSRNOP00000036626/1-999 EGHLHLAQFLVKDCGADVRLRALDGMSSLHAAAARGHYSLVVWLVTFTDIGLTARDNEGA XP_004868583.1/1-1007 EGHLHLAQFLVKDCGADMHLRALDGSSALHAAAARGHCPLVVWLVTFTDISLMARDNEGA ENSCPOP00000006191/1-1003 EGHLHLAQFLVKDCGADVHLRALDGMSPLHAAAARGHYSLVVWLVNFTDIGLMVRDDEGA *****************::****** *.******:** .******.****.* .**:*** ENSP00000339115/1-1005 TALHFAARGGHTPILDRLLLMGTPILRDSWGGTPLHDAAENGQMECCQTLVSHHVDPSLR ENSMUSP00000086294/1-1005 TALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGHMECCQTLLSHHVDPFLR ENSRNOP00000036626/1-999 TALHFAARGGHTPILDRLLLMGAPIMRDSWGGTPLHDAAENGHMECCQTLLSHHVDPFLR XP_004868583.1/1-1007 TALHFAARGGHTPILDRLLLMGAPGTRDSWGGTPLHDAAENGHLECCQTLLSHGVDPSLR ENSCPOP00000006191/1-1003 TALHFAARGGHTPVVDRLLLLGAPVTRDSWGGTPLHDAAENGHTECCQTLLSHHVDPYLR *************::*****:*:* ****************: ******:** *** ** ENSP00000339115/1-1005 DEDGYTAADLAEYHGHRDCAQYLREVAQPVPLLMTPPPPPFPPPPLLATRRSLEDGRRGG ENSMUSP00000086294/1-1005 DEDGYTAIDLAEYHGHQDCAQFLREMSRPVRVLMTPPPPPFPPPPLLAAKLSLEEERRGD ENSRNOP00000036626/1-999 DEDGYTAIDLAEYHGHQDCAQFLREMSRPVPVLMTPPPPPFPPPPLLAAGLPLEEERRGD XP_004868583.1/1-1007 DTDGYTAADLAEYHGHQDCAQFLRAMARPLPTLMTPQPPPFLPPPLSAVKLSLQHGG-GD ENSCPOP00000006191/1-1003 DEDGYTAADLAEYHGHQDCAQYLREMARPVPILMTPPPPPFPPPPLSAAKLTLQDGARGG * ***** ********:****:** :::*: **** **** **** *. .*:. *. ENSP00000339115/1-1005 PGPGNPS-----------------PMSLSPAWPGHPDQPLPREQMTS---PAPPRIITSA ENSMUSP00000086294/1-1005 SGLKSPS-----------------SATLSPVWPA---QPVPREPMAC---TAPLRVTTPD ENSRNOP00000036626/1-999 SGLRSPS----------------------SAWPA---QPVPREPMAC---TAPLSVTSSA XP_004868583.1/1-1007 PGHGSPTRSPSPAPEAPTPLHFSAASTLSPTWPG---QPSLREPLAC---PPGPSGTP-A ENSCPOP00000006191/1-1003 PRHGSPT-----------------PATLSPAWPG---QPILREPTACTMLPSVPTEKPTA . .*: ..**. ** ** :. .. . ENSP00000339115/1-1005 TADPEGTETALAGDTSDGLAALQLDGLPSGDIDGLVPTRDERGQPIPEWKRQVMVRKLQA ENSMUSP00000086294/1-1005 A--LQGPEVEA-RDSRAGLATLQLDGLPAGDLDMLVPTQDERGRPIPEWKRQVMVRKLQA ENSRNOP00000036626/1-999 A--LQGAEVEP-LDSHDGLTTLQLDRLPSGDLDMLVPTQDERGRPIPEWKRQVMVRKLQA XP_004868583.1/1-1007 T--PKGPEMAL-GDAPNGLAVLRLDGLPSGDLDGLVPTRDEQGRPIPEWKRQVMVRQLQA ENSCPOP00000006191/1-1003 G--PQGAEVAL-EDIPNSLAALQLEGLSSGDLDGLVPTRDEQGRPIPEWKRQVMVRQLQA :*.* * .*:.*:*: *.:**:* ****:**:*:************:*** ENSP00000339115/1-1005 RLGAESSAEAQDNGGSS--GPT--EQAAWRYSQTHQAILGPFGELLTEDDLVYLEKQIAD ENSMUSP00000086294/1-1005 RLGADHPPEDQDQSQRQDSGPTAAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQIND ENSRNOP00000036626/1-999 RLGADHPPEDQDQSQRQDSGPTPAEQATWRYSQTHQAILGPFGELLTEDDLVYLEKQIND XP_004868583.1/1-1007 RLGAEDGAAEAQVSGGSA-GPT--EPAPWQYAQVHQAILGPFGELLTEDDLLYLEKQIAD ENSCPOP00000006191/1-1003 RLGEEDSATEAQDGGSRSAGPA--EPAPWRYSQIHQAILGPFGELLTEDDLVYLEKQIAD *** : . : . **: * *.*:*:* *****************:****** * ENSP00000339115/1-1005 LQLRRRCQEYESELGRLAAELQALLPEPLVSITVNSHFLPRAPGLEVEEASIPAAEPAGS ENSMUSP00000086294/1-1005 LQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLEDEEAPVLATELEAS ENSRNOP00000036626/1-999 LQLRRRCQEYESELGRLAAQLQALLPEPLVSITVNSHFLPRAPGLDDEEGPALAPELEAS XP_004868583.1/1-1007 LQLRHRCQEYESQLSRLAAELQALLPEPLVSITVNSHFLPQAPGLEDEGGPMPAAKPKDP ENSCPOP00000006191/1-1003 LQLRRRCQEYESQLGRLAAELQALLPEPLVSITVNSHFLPRAPGLDDQSGPAQAAEPEDS ****:*******:*.****:********************:****: : .. *.: . ENSP00000339115/1-1005 AEASEVAPGVQPLPFWCSHISRLVRSLSLLLKGVHGLVQGDEKPSTRPLQDTCREASASP ENSMUSP00000086294/1-1005 EEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPSPVPQDLGKETIAGP ENSRNOP00000036626/1-999 EEPGKAEPRGQPLPFWCSHIGRLVRSMSLLLKGMNGLAQGEEKPPASVPQDPSKETMAGP XP_004868583.1/1-1007 GEARTAEPGGQPLPFWCSHIGRLVRSLSLLLKGMNGPVQAEEPEAALAPQDARREALASP ENSCPOP00000006191/1-1003 SEAGMAEPGGHPLPFWCVHIGRVVRSLSLLLKGVNGLAQGEEPAAAPAPKDTGREVPVGL *. . * :****** **.*:***:******::* .*.:* .: :* :*. .. ENSP00000339115/1-1005 PRSEAQRQIQEWGVSVRTLRGNFESASG--PLCGFNPGPCEPGAQHRQCLSGCWPALPKP ENSMUSP00000086294/1-1005 SRSEAQREIQECGVSVRTLRGNFEFAPD--LPCALNSGPCELGVRPGQCLRGCWSAPPQP ENSRNOP00000036626/1-999 SRSEAQREIQECGVSVRTLRGNFEFAPD--LPCASNSGPCELGARPGQCLRGCWSAPPQP XP_004868583.1/1-1007 ARSEAQREIQGWGVSVQTLRGNFESVPDAIPPCAPSPGLYEPGAWPMQCPGGCQLAPPKP ENSCPOP00000006191/1-1003 ARSEAQREIQGWGVSVQTLRGHFESVPNACPSCVPSPSLC---ARPAQCTGGCWPAEPHP .******:** ****:****:** ... * ... . ** ** * *:* ENSP00000339115/1-1005 RSGLASGEPRPGDTEEASDSGISCEEVPSEAGAAAGPDLASLRKERIIMLFLSHWRRSAY ENSMUSP00000086294/1-1005 RGDAMGGEPGPGDTEEASDSGISCEEAPSEAGAGPGLDLASLRKERIVMLFLGHWKKSAY ENSRNOP00000036626/1-999 RGEPMGREPRPGDTEEASDSGISCEEAPSEAGAGPGLDLANLRKERIVMLFLGHWKKSAY XP_004868583.1/1-1007 RGRPARGEHRPQATEEA----------PSEAGALPGPDLASLRKERIVMLFLSHWKRSAC ENSCPOP00000006191/1-1003 RGGPAGGEPGPGDAEEASDSGISCEEAATEAGVLPRPDIANLRKERIVTLFLGHWKRSAY *. * * :*** .:***. . *:*.******: ***.**::** ENSP00000339115/1-1005 TPALKTVACRTLGARHAGLRGQEAARSPGPPSP-PSEGPRLGHLWQQRSTITHLLGNWKA ENSMUSP00000086294/1-1005 TPALRTAACRTLEAQRARSRGPEAAGSPRPSSPQPSDGPRLGHLWQQRGIITHLLGTWKA ENSRNOP00000036626/1-999 TPALRTAACRTLEAQRARSRGPEAASSPRPLSPQPSDSPRLGHLWQQRGIITHLLGTWKA XP_004868583.1/1-1007 TPALRTAAYRTPEAQRAHPRGPEPAGSLHPPSLPPSPSPRLGHLWHQRSAVAHLLGSWKA ENSCPOP00000006191/1-1003 TPALRTAACRTLEARRAQQQGPKPPSSPHPPSPTPGPSSRLGHLWQQRSAIAHLLGTWKA ****:*.* ** *::* :* :.. * * * *. ..******:**. ::****.*** ENSP00000339115/1-1005 IMAHVPARQLRRLSRQPRGALSPEQFLPHVDGAPVPYSSLSLDLFMLGYFQLLECDLPAE ENSMUSP00000086294/1-1005 IMAHVPARQLRRLSRRERGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGYFQLLECDLPAE ENSRNOP00000036626/1-999 IMAHVPARQLRRLSRRARGPLSPEQFLPHVDGAPVPYNSLSLDLFMLGYFQLLECDLPAE XP_004868583.1/1-1007 ILAHVPTRQL-RLSRRPQGPLSPEQFLPHVDGAPMPYSSLSLDLFMLGYFQLLECELPPE ENSCPOP00000006191/1-1003 ILAHVPTRQLRRLSRRPHGPLSPEQFLPHVDGAPVPYCSLSLDLFMLGYFQLLECELPPE *:****:*** ****: :*.**************:** *****************:**.* ENSP00000339115/1-1005 ERKLRHLLCFEVFEHLGTHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQRP ENSMUSP00000086294/1-1005 ERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQGP ENSRNOP00000036626/1-999 ERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQGP XP_004868583.1/1-1007 ERKMRHLLCFEVFEHLGAHGWEAVRAFHKAVMDEVAAGHRAWSDSLEDIKARFFGCSQGP ENSCPOP00000006191/1-1003 ERRARHLLCFEVFEHLGAHGWEVVRAFHKAVTDEVAAGRRAWTDGFEDIKARFFGSSQAP **: *************:****.******** ******:***:*.:*********.** * ENSP00000339115/1-1005 AWDTEPGRKSGLTLLGPLPHAAVPCSGPEPT-AQRLGSRSQQGSFNGEDICGYINRSFAF ENSMUSP00000086294/1-1005 PWDVEPGRKLGLTPLGSLPHASLPGSGPEPAVPPRLGSDSQGSSFNSGDICGYIDRSFAF ENSRNOP00000036626/1-999 PWDVEPGRKLGLTPLGSLPHAALPGSGPEPA-SPRLGSNSQQGSFNSGDICGYIDRSFAF XP_004868583.1/1-1007 AWDPEPCRESGVTPLGPLPSPAVPSSVPKPV-AQWPGPGSQQGSFNSEDICSYMDRSFAF ENSCPOP00000006191/1-1003 AWDTEPGRKSGVTPLGPLPRPTVPNAVPEPA-AQRPGPSTQRGSFNSEDICGYIDRSFAF .** ** *: *:* **.** .::* : *:*. . *. :* .***. ***.*::***** ENSP00000339115/1-1005 WKEKEAEMFNFGE ENSMUSP00000086294/1-1005 WKEKEAEMFNFGE ENSRNOP00000036626/1-999 WKEKEAEMFNFGE XP_004868583.1/1-1007 WKEKEAEMFHLGE ENSCPOP00000006191/1-1003 WKGKEAEMFHLGA ** ******::*