CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000095254/1-729 MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKE--------- ENSRNOP00000045021/1-738 MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKE--------- ENSP00000375857/1-808 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- ENSCPOP00000006108/1-604 -------VSNQISGLLQ-----AEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYY XP_004868582.1/1-858 MASPAGARSTEVDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYY . ::. * ***************************** ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 -------------EDSERYSRRSRRNTSASDEDERMSVGSRGSLR--------------- ENSCPOP00000006108/1-604 GLDTKWGDIEQWMEDSERYSRRSRRLASASDEDERLSVGSRGSLRSQPDLESGGPYAWSN XP_004868582.1/1-858 GLDTKWGDIEQWMEDSERYSHRSRRLTSASDEDERLSVGSRGSLR-------------TN ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 ------------------------------------------------------------ ENSCPOP00000006108/1-604 GYDGELYGSQAPSRRSGR----------------------------------------PS XP_004868582.1/1-858 GYDGDLYGSQPPNRRSGRIPSATVVCRLPLPPLPVRTPRRGGSRALVTARGDCSHGGLSS ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 ------------------------------------------------------------ ENSCPOP00000006108/1-604 YL-----------------CG--------------------------------------- XP_004868582.1/1-858 LLPGTADPGDGDAAASAAGCGPSTRASGSPVVALLPSHSLPRMEAEAVAPFPPPRCVACP ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 ------------------------------------------------------------ ENSCPOP00000006108/1-604 --------------AVRPAGSYRASVFQESNLCSVPSAP--------------------- XP_004868582.1/1-858 LVTSSGHFSLFNVTSTEPSGCLDCNQFAE-NPCTFPPAPWALGSGLKVRHGRCEGSRMPA ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 ------------------------------------------------------------ ENSCPOP00000006108/1-604 ----------------------------PPRPRQ-------------------------- XP_004868582.1/1-858 SQQPLHMSESQCPGRVPLTGWAAAAQPWPPEPASSGGEATRQPTCARVWVSGESGGGARG ENSMUSP00000095254/1-729 ------------------------------------------------------------ ENSRNOP00000045021/1-738 ------------------------------------------------------------ ENSP00000375857/1-808 ------------------------------------------------------------ ENSCPOP00000006108/1-604 ---------------------------------------------------------PSE XP_004868582.1/1-858 HPARCPPDVSPPSHLACFWAPAGRRWCSDPLFQSQASVFQDSSVGRAQRGSTCGSLAPSE ENSMUSP00000095254/1-729 -----------------------VEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGS ENSRNOP00000045021/1-738 -----------------------VEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGS ENSP00000375857/1-808 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS ENSCPOP00000006108/1-604 YSGHLNSGSRASSRASSARASPVVEERPEKDFTEKGSRNMPSLSAATLASLGGTSSRRGS XP_004868582.1/1-858 YSGLLSSGSCASSRASSARASPVVEERPEKDFTEKGSRSMPGLSAATLASLGGSSSRRGS *****:***:*****.**.***********:****** ENSMUSP00000095254/1-729 GDTSISMDTEASIREI------------------------KDSLAEVEEKYKKAMVSNAQ ENSRNOP00000045021/1-738 GDTSISMDTEASIREI------------------------KDSLAEVEEKYKKAMVSNAQ ENSP00000375857/1-808 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ ENSCPOP00000006108/1-604 GDTSISMDTEASMREIKELNELKDQIQDVEGKYMQGLKELKDSLAEVEEKYKKAMVSNAQ XP_004868582.1/1-858 GDTSISIDTEASLREIKELNELKDQIQDVEGKYMQGLKEMKDSLTEVEEKYKKAMVSNAQ ******:*****:*** ****:*************** ENSMUSP00000095254/1-729 LDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEA ENSRNOP00000045021/1-738 LDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEA ENSP00000375857/1-808 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA ENSCPOP00000006108/1-604 LDNEKTNFMYQVDTLKDALLELEEELAEARRQCEEKSKEFERERHAHSVLQFQFAEVKEA XP_004868582.1/1-858 LDNEKTNFLYQVDTLKDMLLELEEELAEARRQYEEKTKDFEREKHAHRALQFQFAEVKEA ********:******** ******:***::** ***.*:****:*** *********** ENSMUSP00000095254/1-729 LRQREEMLE--------------------------------------------------- ENSRNOP00000045021/1-738 LRQREEMLE--------------------------------------------------- ENSP00000375857/1-808 LKQREEMLE--------------------------------------------------- ENSCPOP00000006108/1-604 LRQRDEMLEEIRQLQQKQAGYIREISDLQETIEWKDKKIGALERQKEFFDSVRSERDDLR XP_004868582.1/1-858 LRQRDEMLEEIRQLQQKQASYIGEISDLQETIEWKDKKIGALERQKEFFDSIRSERDDLR *:**:**** ENSMUSP00000095254/1-729 -----------KHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKSAGEGTLGK ENSRNOP00000045021/1-738 -----------KHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKAAGEGTLGK ENSP00000375857/1-808 -----------KHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR ENSCPOP00000006108/1-604 EEVAKLKEECKKHGIILNSEVATNGETSDTLNNVGSPGPTKMSKEEINALKSASDGTL-- XP_004868582.1/1-858 EEIVKLKEEFKKHGITLNSEVATNGETSGTLNNVGHPGPTKLTKEEVNALQPSGDGTL-- **** ****:*******.*:*:** .***::***:***:.:.:*** ENSMUSP00000095254/1-729 AKEVEVKKEIVEKVGQRETLQNSEQEQPKPNTGKDCVDRGVSHPGEKAENQRPAEDSALS ENSRNOP00000045021/1-738 AKEVEVKKEIVEKVGQRETLQDSEQEQPKLNTGKDCVDRGVLHPGEKAENQRPVEDSALS ENSP00000375857/1-808 ASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPF ENSCPOP00000006108/1-604 --DIRLKKLIDE---------------------RECL----------------------- XP_004868582.1/1-858 --DIRLKKLIDE---------------------RECL----------------------- ::.:*: * ::*: ENSMUSP00000095254/1-729 PGPLAGAKCEQQVQSQDQENTSDLKNSEQIESHKVTNKSDSRASNSPEQSSCLEGLDSEV ENSRNOP00000045021/1-738 PGPLAGAKCEQEVQSQDQENTSILKSPEQIESHEVTNKSDSRDSNSPEPSSCRGGLDSEV ENSP00000375857/1-808 LGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLD--- ENSCPOP00000006108/1-604 --------------------------LEQIK--KLKGQLEERQKGN--------KLD--- XP_004868582.1/1-858 --------------------------LEQIK--KLKGQLEGKPKNS--------KLD--- *:: :: . : : ** ENSMUSP00000095254/1-729 PGPT----------------EDLKTDLGKGSFEPCPDYILGQTAEIDKVTCTDSRGTGGN ENSRNOP00000045021/1-738 SGPTALGIKNQSENSMDSQGKENQEDLGKGSFEPRPDHVLGQTPEIDKVSCTDSRGTGGN ENSP00000375857/1-808 ---------------------------------------------------------GGN ENSCPOP00000006108/1-604 ---------------------------------------------------------GPR XP_004868582.1/1-858 ---------------------------------------------------------HSR . ENSMUSP00000095254/1-729 QREDEVQAGDTTVEDQVGTVASGPAKQSKGTENHGESCLKDG-------LGQSSEREL-T ENSRNOP00000045021/1-738 HLEDVVQAGDTIVEDQVGTMAS--AEQSKSMENHIGRSLNDG-------LGQSSEREL-A ENSP00000375857/1-808 HTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTN ENSCPOP00000006108/1-604 AKEDTVENG---------------------TDAHILDLQRDA-----------------N XP_004868582.1/1-858 AAEDVLENG---------------------TGVHVLDLQRDA-----------------N *: : . * : ENSMUSP00000095254/1-729 QEVAEPEEAIVQIPQAGGENTITKADDAEGRDEKPIQAEAQASPGAPINQSGHQDTTGPG ENSRNOP00000045021/1-738 HEAAELEEALTQSSQAGGENTVTEAEDAAVRDEKPLQADVQATPAAPTVQSGHQDTTGPG ENSP00000375857/1-808 QEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG--TEGNCQEATGPS ENSCPOP00000006108/1-604 RQISDLKFKL-------------------------------------------------- XP_004868582.1/1-858 RQISDLKFKL-------------------------------------------------- :: :: : ENSMUSP00000095254/1-729 STDAQRTPPHAKERKKQGKSEQQAEALDSPQKKTKNKKKKNKKKKAATPAETCRDANEEL ENSRNOP00000045021/1-738 STDTKHTSPHAKERNK-AKSEQQAEALDSPQKKTKNKKKKNKKKKAAAPMETCKDANEES ENSP00000375857/1-808 TVDTQNEPLDMKEPDE-EKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKEL ENSCPOP00000006108/1-604 -----------------AKSEQEITALE--QNIIRLESQVSRYKSAAENAEKIED----- XP_004868582.1/1-858 -----------------AKSEQEITALE--QNVIRLESQVSRYKSAAENAEKIED----- **:*: **: *: : :.: .: *.:. *. .* ENSMUSP00000095254/1-729 NCQDPDVGDMEEEERLQVTDKKQA-------SGSPEQKIRAGSREPVEDPQSGSSGKQNK ENSRNOP00000045021/1-738 SCQDPDVGDGEEEERVQATDKKWA-------AETPELK---------EDPQSRPSGKQND ENSP00000375857/1-808 TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGK ENSCPOP00000006108/1-604 --------ELKAEKRKLQRELRSA------------------------------------ XP_004868582.1/1-858 --------ELKAEKRKLQRELRSA------------------------------------ : : *:: : : * ENSMUSP00000095254/1-729 VEED-GPTEGPTD--ILDQNSPQCEDREISP--------VGEKGPQCDTSQIGSEEGHVT ENSRNOP00000045021/1-738 AEEDSGPAEGPTD--VLDQNSLQCADGDISP--------VGRKGPQRDASQIGGEEGLVP ENSP00000375857/1-808 LDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSP ENSCPOP00000006108/1-604 ---------------LDKTEELEVSNGHLVK----------------------------- XP_004868582.1/1-858 ---------------LDKTEELEVSNGHLVK----------------------------- : . : : : : ENSMUSP00000095254/1-729 -------------------------------------SQHGGQA----VENHNLDNSDLS ENSRNOP00000045021/1-738 -------------------------------------SQHPGQADEKGIEGHSVDNSDLS ENSP00000375857/1-808 AEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLS ENSCPOP00000006108/1-604 ------------------------------------------------------------ XP_004868582.1/1-858 ------------------------------------------------------------ ENSMUSP00000095254/1-729 G---QLEGFNSESGGQAREEVGNSKSKEDCTMS ENSRNOP00000045021/1-738 G---ELGGFNSESGEQAREEVGNSKSKEDCTMS ENSP00000375857/1-808 APGREPGHFNPESREDTRGGNEKGKSKEDCTMS ENSCPOP00000006108/1-604 ----RL--------------------------- XP_004868582.1/1-858 ----RLEKMKANRSALLTQQ------------- .