CLUSTAL W(1.81) multiple sequence alignment ENSP00000367581/1-2663 MPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKL ENSMUSP00000095938/1-2664 MPKGGCSKTPQQEDFALSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKL ENSRNOP00000035742/1-2629 MPKGGCSKTPQQEDCSLSNDMVEKQTGKKDKDKVSLTKTPKLDRTDGGKEVRERVTKRKL XP_004842705.1/1-2514 --------------------------------------------MSGGR----------- ENSCPOP00000005852/1-2553 MPKSGCSKTPQQEDFPLSNDMVEKQTGKKDKDKVSLTKTPKLDRNDGGKEVRERTTKRKL .**: ENSP00000367581/1-2663 PFTAGANGEQKDSD----------------------TEKQGPERKRIKKEPVTRKAGLLF ENSMUSP00000095938/1-2664 PFTVGANGEQKDSDTDSFGHRTFNWGSPLPFSLTCHTEKQGPERKRIKKEPVARKSGLLF ENSRNOP00000035742/1-2629 PFTVGANGEQKDSD----------------------TEKQGPERKRIKKEPVPRKSGLLF XP_004842705.1/1-2514 ------------------------------------PACTGP------------------ ENSCPOP00000005852/1-2553 PFTVGANGEQKDSDT---------------------EEKQGPERKRIKKEPVARKSGLLF ** ENSP00000367581/1-2663 GMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTK ENSMUSP00000095938/1-2664 GMGLSGIRAGYPLSERQQVALLMQMTAEESANSP-DTTPKHPSQSTVCQKGTPNSASKTK ENSRNOP00000035742/1-2629 GMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTK XP_004842705.1/1-2514 ---------------------------------PSEETP--------------------- ENSCPOP00000005852/1-2553 GMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTK * : ** ENSP00000367581/1-2663 DKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAK ENSMUSP00000095938/1-2664 DKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAK ENSRNOP00000035742/1-2629 DKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAK XP_004842705.1/1-2514 ---------GASRSSSVRVQTSTSRTLQCL----------FPGWTALHEACNRGYYDVAK ENSCPOP00000005852/1-2553 DKVNKRNERGETRLHRAAIRGDARRIKELINEGADVNVKDFAGWTALHEACNRGYYDVAK * :* . :: .: * : : *.***************:** ENSP00000367581/1-2663 QLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPT ENSMUSP00000095938/1-2664 QLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPT ENSRNOP00000035742/1-2629 QLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPT XP_004842705.1/1-2514 QLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPT ENSCPOP00000005852/1-2553 QLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVASSPT ********************************************************.*** ENSP00000367581/1-2663 MVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQK ENSMUSP00000095938/1-2664 MVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK ENSRNOP00000035742/1-2629 MVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK XP_004842705.1/1-2514 MVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK ENSCPOP00000005852/1-2553 MVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQK ************************************************** ********* ENSP00000367581/1-2663 ATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIA ENSMUSP00000095938/1-2664 TVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKANSFISIPKMEVKSYSKNNTLA ENSRNOP00000035742/1-2629 TVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRREAKSNSFISIPKMEVRSYSKNNTLA XP_004842705.1/1-2514 AVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIA ENSCPOP00000005852/1-2553 TVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYSKNNTIA :.:*******************************:*:*:***********:**:****:* ENSP00000367581/1-2663 PKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKR ENSMUSP00000095938/1-2664 PKKAAHRILSDTSDEEDVSVSIGAGEKLRLSAHTMLPGSKARESSSSRQQKEKNKLKKKR ENSRNOP00000035742/1-2629 PKKAAHRILSDTSDEEDVSASIGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKR XP_004842705.1/1-2514 PKKAAHRILSDTSDEEDTGLAVGAGEKLRLSAHSVLPSSKVREPSNSRQQKEKSKVKKKR ENSCPOP00000005852/1-2553 PKKASHRILSDTSDEEDTSLTVGASEKLRLSAHSILPSSKVREPSNSR------------ ****:************.. ::*:.********::**.**.**.*.:: ENSP00000367581/1-2663 KKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSL ENSMUSP00000095938/1-2664 KKETKGKEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLKGSPLVLKDPSLFSSL ENSRNOP00000035742/1-2629 KKETKGKEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLKGSPLVLKDPSLFSSL XP_004842705.1/1-2514 KKEAKSKEVRFGKRNDKFCSSESESESSESEEDDDDSVGSTGCLKGSPLVLKDPSLFSSL ENSCPOP00000005852/1-2553 --------VRFGKRNDKFCSSESESESSESEEEDGDSVGSTGCLKGSPLVLKDPSLFSSL ******.****** ******** *:* **:**:******************* ENSP00000367581/1-2663 SASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESD ENSMUSP00000095938/1-2664 SASSTSSHGSAVAQKHGSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESD ENSRNOP00000035742/1-2629 SASSTSSHGSAVAQKHSSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESD XP_004842705.1/1-2514 SASSTSSHGSAVAPKHGTNHGDQHAKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESD ENSCPOP00000005852/1-2553 SASSTSSHGSAVAPKHSANHSDQHNKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESD **********:.* *:...* *** *********:***************:** ****** ENSP00000367581/1-2663 YSSEGSSVESLKPVRKRQEHRKRASLS----EKKSPFLSSAEGAVPKLDKEGKVVKKHKT ENSMUSP00000095938/1-2664 CSSEGSSVESLKPTRRKQEHRKRGVLQSAPSEKRSSFHPCTDGAVPKLDKEGKVVKKHKT ENSRNOP00000035742/1-2629 CSSEGSSVESLKPTRRKQEHRKRGSLQSMP-ERRGTFHPCADGAVPKLDKEGKVVKKHKT XP_004842705.1/1-2514 CPSEGSSVESLKPTRRKQELRKRGSLPSAPPEKRGTCHPGTDGAVPKLDKEGKVVKKHKT ENSCPOP00000005852/1-2553 CPSEGSSVESLKPTRRKQGLRKRASLPSVPPEKRGICHPSTDGAVPKLDKEGKV------ .***********.*::* ***. * *::. . ::************ ENSP00000367581/1-2663 KHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHF ENSMUSP00000095938/1-2664 KHKHKHKEKGQCSVSQELKLKSFTYEYEDSKQKSDKAILLESDLSTENKLKVLKHDREHL ENSRNOP00000035742/1-2629 KHKHKHKEKGPCSVSQELKLKSFTYEYEDSKQKPDKAILLENDVSTENKLKVLKHDRD-- XP_004842705.1/1-2514 KHKHKNKEKGQCSVSQELKLKSFTYEYEDSKQKSEKAILLDNDISTDNKLKVLKHDRDHF ENSCPOP00000005852/1-2553 -----DKEKGQCSVSQELKLKSFTYEYEDSKQKPDKAILLDNDIAPE-KLKVLKHDRDHF .**** **:*******************.:*****:.*::.: *********: ENSP00000367581/1-2663 KKEEKLSKMKLEEKEWLF--------KDEKSLKRIKDTNKDISRSFREEKDRSNKAEKER ENSMUSP00000095938/1-2664 KKEDKLGRMKPEDKDWLF--------KDEKVLKRIKDANKDMSRAFREDKDRASKAERER ENSRNOP00000035742/1-2629 ----KLSKTKSEDKEWLF--------KDEKALKRMKDVSKDTSRAFREERDRPSKTERER XP_004842705.1/1-2514 KKEEKLSKLKSEDKEWIFKEEMLKVSKDEKLMKR----AKDIGRSFREEKDRSGKTEREK ENSCPOP00000005852/1-2553 KKEEKLGKLKSEDKEWLFKEEILKVSKDEKSLKR----AKDIGRSFREEKDRSSKAEREK **.: * *:*:*:* **** :** ** .*:***::**..*:*:*: ENSP00000367581/1-2663 SLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEK ENSMUSP00000095938/1-2664 ATKDKSPKEEKLRLYKEERKKKSKDRASRLERKNDMKEDKLSKEKEKAFKEDKEKLKKEK ENSRNOP00000035742/1-2629 STKEKSPKEEKLRLYKEERKKKSKDRPFKLEKKNDMKE--VSKEKEKAFREDKEKLKKEK XP_004842705.1/1-2514 AVKEKSPKEERLRLYKEEKKKKSKDRPSKLEKKNDMKEDRACKE--------KEKLKKEK ENSCPOP00000005852/1-2553 TMKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNEVKEDRTCKE--------KEKLKKER : *:******:*******:*******. :**:**::** .** *******: ENSP00000367581/1-2663 VYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYR ENSMUSP00000095938/1-2664 LYREDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDS-VTDYR ENSRNOP00000035742/1-2629 LCRDDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDS-VTDYR XP_004842705.1/1-2514 GYRDDAAFDEFCSKTQFLENEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSPVTDYR ENSCPOP00000005852/1-2553 GYRDDASFDEYCGKTQFLENEDSKFSLSDDQPERWFSDLSDSSFDFKGEDSWDSPVTDYR *:*::**::*.*.***::**:******** :********************* ***** ENSP00000367581/1-2663 DMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEK ENSMUSP00000095938/1-2664 DIKNDSVAKLILETVKEDSKEKKRDNKIREKRDFKDSFFRKRDRDCLDKNSEKRRDQTEK ENSRNOP00000035742/1-2629 DIKSDSVAKLILETVKEDSKEKKRDNKTREKRDFRDSFFRKRDRDCVDRNSEKRRDHTEK XP_004842705.1/1-2514 DIKNDSVAKLILETVKEDSKEKKRDNRAREKRDFRDSFFRKKDRDCLDKSSEKRRDQVEK ENSCPOP00000005852/1-2553 DIKSDSVAKLILETVKEDSKEKKRDIRAREKRDFRDSFFRKKDRDYLDKNSEKRRDQTEK *:*.*****************::** : *****:::.****:*** :*:.****:::.** ENSP00000367581/1-2663 HKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFK ENSMUSP00000095938/1-2664 HKSIPSYLSEKDKKRRESAEGGRDRRDG----------RIRSEEVHREDLKECGFESSFK ENSRNOP00000035742/1-2629 QRSFPSYLSEKDKKRRESAEGGRDRRDG----------RIRSEEVHREDLKECGCDSTFK XP_004842705.1/1-2514 HKGVPSYLSEKDKKRRECAEGGRDRRDGLDGSRERKEARLRPEEAHREDLKDCGCESAFR ENSCPOP00000005852/1-2553 HKGIPSYLSEKDKRRRESAEAGRDRRDGLDGSRERRDARLRPEEAHREDLKDCSCESAFR ::..*.*******:***.**.****:*. * :.**.***:**:*. :* *: ENSP00000367581/1-2663 DKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKC ENSMUSP00000095938/1-2664 DKSDCDFPKNLEPWERPHAAREKEKKDALEKERKEKGRADKYKEKSSERERSDKSTLDKC ENSRNOP00000035742/1-2629 DKSDCDFTKTLEPWERPHAAREKEKKDALEKDRKEKGRAEKYKDKSGERERNEKSILEKC XP_004842705.1/1-2514 DKPDSDLPKGLEPWERPHALR-------LEKDRKEKVRVEKCKDKSLDRDKSEKSLLEKC ENSCPOP00000005852/1-2553 DKPDCELAKGLEPWERHHAAR--------EKERKEKMRAEKYKDKALDRDKGEKSVLEKC **.* :: * ****** *. * :*:**** : :: *:*: ::::.:** *:** ENSP00000367581/1-2663 QKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDK ENSMUSP00000095938/1-2664 QKDKEFEKCFKEKKDGKEKHKDIHSKD--RKASFDQLREKKEKVFSSIISEDFSERKDDR ENSRNOP00000035742/1-2629 QKDKEFEKCFKEKKDGKEKHKDTHSKD--RKTPFDQLREKKEKAFSSLISEDFSERKDDR XP_004842705.1/1-2514 QKDKEFDKCFKEKRDAKEKHKEAHSKD--RKASLDQGREKKEKMFPGLLSEDFSEKKDEK ENSCPOP00000005852/1-2553 QKDKEFDKCFKEKKDGKEKHKEAHSKD--RKASLDPARDKKEKMFPGLLSEDFS------ ******:******:* *****: *.** **:.:* ::**** *..::***** ENSP00000367581/1-2663 KGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRK ENSMUSP00000095938/1-2664 KGKEKSWYIADIFTDESEDEKDDCVAGSFKATEASDTQRVDGLPEKEEGRE-HPSDRHRK ENSRNOP00000035742/1-2629 KGKEKSWYIADIFTDESEDEKEECVASSFKTGETGDSQRAESLQEKEDGRE-HPSDRHRK XP_004842705.1/1-2514 KGREKSWYIADIFTDESEDEKDDYMASSFKAGEAGDAQRGDSLQDKEDGRELHLLDRHRK ENSCPOP00000005852/1-2553 ------WYIADIFTDESEDEKDDYVASGFKVGEAGDTQRGDSPQDKEDGREPHLSDRHRK *************:::. :...** *:.* * :. :**:*** : ***** ENSP00000367581/1-2663 -SSDKQHPERQKDKEPRDRRKDRGAADAGRDKK---EKVFEKHKEKKDKESTEKYKDRKD ENSMUSP00000095938/1-2664 SSSDRQHTEKPRDKEPKEKKKDRGASEGGKDKKEKMEKIFEKHKEKKDKECAERYKDRKE ENSRNOP00000035742/1-2629 ASSDRQHTEKPRDKEPKEKRKDRGAAEGGKDKK---EKIFEKHKEKKDKECAEKYKERKD XP_004842705.1/1-2514 -SSDRQHAEKPRDKEPKEKRKDRVAADSGRDRK---DKIFEKHREKKDKECAERYKDRKD ENSCPOP00000005852/1-2553 SSSDRQH---------------RAAVEGGRDKK---DKIFEKHREKKDKECAERYKDRKD ***:** * * :.*:*:* :*:****:******.:*:**:**: ENSP00000367581/1-2663 RASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHS--KERKSSRSADAEKSL ENSMUSP00000095938/1-2664 RASADSAPEKKNKQKLPEKVEKKHFAEDKVKSKHKEKPEKEHSRERERKPSRGPDVEKSL ENSRNOP00000035742/1-2629 RASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHS--RERKSSRGPDVEKSL XP_004842705.1/1-2514 RASVDSAQEKKNKQKLPEKVEKKHSTEDKAKSKHKDKPEKEHS--KERKGSRGAEAEKSL ENSCPOP00000005852/1-2553 RVSVDSTQEKKNKQKLPEKVEKKHSTEDKAKSKHKEKPEKEHA--KERKGSRGPEAEKSL *.*.**: :**********.**** .***.*****:*.:*:*: :*** **..:.**** ENSP00000367581/1-2663 LEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACL ENSMUSP00000095938/1-2664 LEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARDSACL ENSRNOP00000035742/1-2629 LEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARESTCL XP_004842705.1/1-2514 LEKLEEEALHEDREDSNDKASEVSSDSFTDRGQEPGLSALLEVSFSEPP-DDKARES-CL ENSCPOP00000005852/1-2553 LEKLEEEALHEYREDSNDKASEVSSDSFTDRGPEPGLSALLEVSFSEPP-DDKARET-CL **********: ******* ********:*:* **.*:::*****:*** :**.*:: ** ENSP00000367581/1-2663 PEKL--KEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKE--GGSRKDSGQYEKDF ENSMUSP00000095938/1-2664 SEKL--REKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDSISSVRKDASQFEKDF ENSRNOP00000035742/1-2629 SEKLKERERERHRHSSSSSKKSHERERAKKEKADKKEKGEDYKDG-GGGRKDASQYEKDF XP_004842705.1/1-2514 TEKL--RDRERHRHSSSSSKKSHDRERAKKEKAEKKEKAEDYKD--GGCRKDSSQYEKDF ENSCPOP00000005852/1-2553 TEKL--RDKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKD--GGTRKDSSQYEKDF .*** :::**************:*********:****.****: .. ***:.*:**** ENSP00000367581/1-2663 LEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINIL ENSMUSP00000095938/1-2664 LDAETYGVSYPTKADVEEELDKAIELFSSEKKDRSDPEREPAKRIEKELKPYGSSAISIL ENSRNOP00000035742/1-2629 ADAEAFGGSYTTKADTEEDLDKAIELFSSEKKDRNDSEREPAKKLEKELKPYGSSTISIL XP_004842705.1/1-2514 LDAEAYGVAYTVKADMEEELDKTVEIFPSEKKERNDPERESAKKIEKELKPYGSSTISIL ENSCPOP00000005852/1-2553 LEAEAYTTSYTVKADIDDELEKTIEIFSTEKKERNDSEREPSKKIEKELKPYGSSAISIL :*::: :* *** :::*:*::*:*.:***::.*.***.:*::**********:*.** ENSP00000367581/1-2663 KEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKD ENSMUSP00000095938/1-2664 KEKKKREKHRERWREEKERHRDKHVDGFLRH--------HKDEPKPAAKDKDNPPNSFKE ENSRNOP00000035742/1-2629 KEKKKREKHREKWREEKEKHRDKHIDGFLRH--------HKDEPKPAAKDKDNPPNCFKE XP_004842705.1/1-2514 KEKKKREKHREKWRDEKERHREKHTDGFLKH--------HKDEPKPAAKDKDNPPNSFRE ENSCPOP00000005852/1-2553 ------------------------TDGFLKH--------HKDEPKPAAKDKDSAPNSFKE **:*:* *:** ***::***..*. ::: ENSP00000367581/1-2663 KSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDG ENSMUSP00000095938/1-2664 KSREESLKLSETKLKEKFKENTEREKGDSIKMSNGNDKLVPSRDSGKKDSRPREKLLGDG ENSRNOP00000035742/1-2629 KSREESLKLSEAKLKEKFKENAEREKGDSVKMSNGNDKPLPSRDANKKDSRPREKLLGDG XP_004842705.1/1-2514 KSRDESLKLSETKLKEKLRENTEREKADSMKISNGSDKLPLARDLGKKDARPREKLLGDG ENSCPOP00000005852/1-2553 KAREEGLKLGEAKPKEKLRENAEREKADLVKISNGNDKPPLARDPGKKDTRPREKLLGDG *:*:*. :*.::* ***:::.:*:**.* :*:***.** ::* .***:********** ENSP00000367581/1-2663 DLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKAKPADDGRKKGLD ENSMUSP00000095938/1-2664 DLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEK-KPTEDGRKKSLD ENSRNOP00000035742/1-2629 DLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEK-KPTDDGRKKSLD XP_004842705.1/1-2514 DLMMTSFERMLSQKDLEVEERHKRHKERMKQMEKMRHRSGDPKLKDKTKPPEEGRKKSLD ENSCPOP00000005852/1-2553 DLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKDKAKPPEDGRKKSLE *****************:****************:**********:* **.::****.*: ENSP00000367581/1-2663 IPAKKPPGLDPPFKDKKLKESTPIPPAA--ENKLHPASGADSKDWLAGPHMKEVLPASPR ENSMUSP00000095938/1-2664 FPSKKALGLD-----KKVKEPAPTLTTG--ESKPHSGPGTESKDWLSGQPLKEVLPASPR ENSRNOP00000035742/1-2629 FPSKKALGLD-----KKVKEPAPVLPTG--EGKPHSGPGTESKDWLAGQPLKEVLPASPR XP_004842705.1/1-2514 VPPKKPLGPDPPFKEKKLKDSAPTPPATAIEGKL--GPGAECKDWPAAPPPKEVLPPSPR ENSCPOP00000005852/1-2553 APPKKPPGPEPPSKEKKLKDPAPTPPAT--ENKP--GLGAECKDWLAGPSLKEVLPASPR *.**. * : **:*:.:* .: *.* . *::.*** :. *****.*** ENSP00000367581/1-2663 PDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHSTPVPTAPTS ENSMUSP00000095938/1-2664 TEQSRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTASTS ENSRNOP00000035742/1-2629 TEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTS XP_004842705.1/1-2514 PEQSRPTGVPT-------PSYEEVMHTPRTPSCSADDYPDLVFDCADSQHSMPVSATSTS ENSCPOP00000005852/1-2553 PEQSRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSATSTS .:*.******* ********************.******:***** **.::.** ENSP00000367581/1-2663 ACSPSFFDRFSVASSGLSEN-ASQAPARPLSTNLYRSVSVDIRRTPEEEFSVGDKLFRQQ ENSMUSP00000095938/1-2664 ACSPPFFDRFSVASSVVSENAAGQTPTRPISTNLYRSISVDIRRTPEEEFSAGDKLFRQQ ENSRNOP00000035742/1-2629 ACSPPFFDRFSVASSVVAEN-AGQTPTRPISTNLYRSISVDIRRTPEEEFSVGDKLFRQQ XP_004842705.1/1-2514 TCSPPFFDRFSVASSGVSEN-PGQTPTRPVSSNLYRSISVDIRRTPEEEFSVGDKLFRQQ ENSCPOP00000005852/1-2553 TCSPPFFDRFSVASGGVSEN-PSQTPTRPVSTNLYRSISVDIRRTPEEEFSVGDKLFRQQ :***.*********. ::** ..*:*:**:*:*****:*************.******** ENSP00000367581/1-2663 SVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLSPGYYSPDYGL----PSPKVDALHCPP ENSMUSP00000095938/1-2664 SVPAPSSFDSPVQHLLEEKAPLPPVPAEKFACLSPGYYSPDYGI----PSPKVDTLHCPP ENSRNOP00000035742/1-2629 SVPAASSFDSPVQHLLEEKAPLPPVPAEKFACLSPEYYSPDYGI----PSPKVDTLHCPP XP_004842705.1/1-2514 SVPAASSFGSPVQHLLEDKAPLPPVPSEKFPCLSPGYYSPDYGIPSGMPSPKVDSLHCPP ENSCPOP00000005852/1-2553 SVPAASSFDSPVQHLLEDKTPLPPVPVDKFACLSPGYYSPDYGI----PSPKVDGLHCPP ****.**:.**: :*:::****** :**.**** *******: ****** ***** ENSP00000367581/1-2663 AAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGALPPD----LDTSEDQQATAAIIP ENSMUSP00000095938/1-2664 TAVVSATPPPDSVFSNLPPKSSPSPRGELLSPAIEGTLPPDLGLPLDATEDQQATAAILP ENSRNOP00000035742/1-2629 TAVVSATPPPDSVFSNLPPKSSPSPRGELLTPAIEGALPPDLGLPLDATEDQQATAAILP XP_004842705.1/1-2514 ACTVSVTPSPEGVFSSLPAKASP-PRGELFAPAVDGALTPDLGLPLDATEDQQATAAIIP ENSCPOP00000005852/1-2553 ASTVGTTPSPEVVFSGLPAKASP-PRGELLAPAVEGALPPDLGLPLDATEDQQATAAIIP :..* .**.*: ***.* .*.** **.**: *:::*:*.** **::*********:* ENSP00000367581/1-2663 PEPSYLEPLDEGPFSAVITEEPVEWAHPS-EQAL-ASSLIGGTSENPVSWPVGSDLLLKS ENSMUSP00000095938/1-2664 QEPSYLEPLDEGPFTTVITEEPVEWTHTAAEQGLSSSSLIASASENPVSWPVGSELMLKS ENSRNOP00000035742/1-2629 PEPSYLEPLDEGPFNTVITEEPVEWTHSAAEQSL-PSSLIASASETPVSWPVGSELMLKS XP_004842705.1/1-2514 PEPSYLEPLDEGPFSTVITEEPGEWAHPAAEQTL-SPSLVTGASENPVSWPVGADLLLKS ENSCPOP00000005852/1-2553 PEPSYLEPLDEGPFSTVITEEPVEWAHSTAEQAL-SSSLVTGASENPVSWPVGADFLLKS *************.:****** **:*.: ** * ..**: .:**.*******::::*** ENSP00000367581/1-2663 PQRFPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKD-GVD ENSMUSP00000095938/1-2664 PQRFAESPKHFCPGESLHSTTPGPYSAAEPTY---PVSPGSYPLPAPEPALEEVKDGGTG ENSRNOP00000035742/1-2629 PQRFAESPKHFCPGEPLHSTTPGPFSAAEPTY---PVSPGSYPLPAPEPALEEVKDGGTG XP_004842705.1/1-2514 PQRFPESPKHYCPAESLHTATPGPFSAAEPPY---PVSPVSYPLPAAEPDLEEVKDDGVG ENSCPOP00000005852/1-2553 PQRFPESPKRYCSAESLHTATPGPFSTAEPPY---PVSPVSYPLPTAEPGLEEVKEDGVG ****.****::*..:.**:::***:*::*..* *.** .*.**..** **:**: *.. ENSP00000367581/1-2663 AVPAAI-STSEAAPYAPPSGLESFFSNCKSLPEAPLDVAPEPACVAAVAQVEALGPLENS ENSMUSP00000095938/1-2664 AIPVAISAAEGAAPYAAPARLESFFSNCKSHPDAPLDTAPEPTGVTAVAQVEALGPLESS ENSRNOP00000035742/1-2629 AIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLESS XP_004842705.1/1-2514 AISA---TTEGGTPYTTPARLESFFGSCKPLPDAPLDQVPEPTCVSTVAQVEALGALESS ENSCPOP00000005852/1-2553 AIPV---ATEEAAPYTTPSRLESFFGSCKPLPDAPLDQAPEPTCVSTGAQVEALGALESS *:.. ::. .:**:.*: *****..**. *:**** .***: *:: *******.**.* ENSP00000367581/1-2663 FLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELPLQTKDAADGEAEPVEESLA ENSMUSP00000095938/1-2664 FLDSNPSISTLSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAAKASPV ENSRNOP00000035742/1-2629 FLDSSHSISALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAETAEASPA XP_004842705.1/1-2514 FLDSGHGLAALGQVEPVPWHDAFTSTEDDLDLGPFSLPELPLQPKDPPDVEMEPAGGSPA ENSCPOP00000005852/1-2553 FLDNGHSLAALGQVEPVPWHDAFTSAEDDLDLGPFSLPELPLQPKDAPDVETEPAEGSPA ***.. .:: *.*****.* :**:..*****************.**..* * *.. * . ENSP00000367581/1-2663 PPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGEPKLDVALEAAV ENSMUSP00000095938/1-2664 PPAESPPGPTGVLGGGDVPAPAAEEPPAPPPQEASPQLST--EPEPSEEPKLDVVLEATV ENSRNOP00000035742/1-2629 PPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLST--EPEPSEETKLDVVLEAAA XP_004842705.1/1-2514 PPGEALPVPAGVSSDGDGPVAEAEDQPAPPTEQAVPRLPA--ELEPSEEPKLDVVLEATV ENSCPOP00000005852/1-2553 PTGGTLPVPSGVGSEGDGPGAVAEEQPVPPPEQTTPRLST--ELKPSEESKLDVVLEATV *. * ..** . ** . :*: *. *.::: .:*.: * :** *.****.***:. ENSP00000367581/1-2663 EAETVPEERARGDPDSSVEPAPVPPE-QRPLGSGDQ-GAEAEGPPAASLCAPDGPAPNTV ENSMUSP00000095938/1-2664 ETEVLADDSAPEASISNSVPAPSPPQ-QQPPGGGDE-EAETEDPSATPCCAPDGPTTDGL ENSRNOP00000035742/1-2629 ETEVLADDSAPEASISNLVPAPSPPEQQRPAGGGDE-ETEAEDPSAAPCCAPDGPTTDGL XP_004842705.1/1-2514 EAEAVADEQAPEDLDSGSVPVPGPPE-WHPLEGGDE--VEAEAPAAAPHCAPDGPPQEAP ENSCPOP00000005852/1-2553 EAEAVADEQVPENPDSSAAPVSSAPE-QCPLEGGDEVEVEAEGPSAAPHCTPNDPTQDAP *:*.:.:: . *. *.. .*: * .**: .*:* *.*:. *:*:.*. : ENSP00000367581/1-2663 AQAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAA--EPKPTAEAPKAPRVEEIPQRMT ENSMUSP00000095938/1-2664 AQAH--------NSAEASCVVAAAEGPPGNVQAEATDPEPKPTSEVPKAPKVEEVPQRMT ENSRNOP00000035742/1-2629 AQAP--------NSAEAACVVAAVEGPPGNIQPEATDPEPKPTSEAPKAPKVEEVPQRMT XP_004842705.1/1-2514 PQAQ--------ADSEATPAATPAEGPLGSVQPGAPEPEPRPAAEAPKAPRVEEVPQRMT ENSCPOP00000005852/1-2553 PQAH--------DGSEATSAATPAESPPGSVQPEAAEPEPRPAAEAPKAPRVEEVPQRMT .** .:**: ..:..*.* *.:*. *. **:*::*.****:***:***** ENSP00000367581/1-2663 RNRAQMLANQSKQGPPPSEKECAPTPAP----VTRAKARGSEDDDAQAQHPRKRRFQRST ENSMUSP00000095938/1-2664 RNRAQMLASQSKQGIPAAEKDPMPTP------ASRAKGRASEEEDAQAQHPRKRRFQRSS ENSRNOP00000035742/1-2629 RNRAQMLASQSKQGIPATEKDSMPAP------ASRAKGRAPEEEDAQAQHPRKRRFQRSG XP_004842705.1/1-2514 RNRAQMLASQSKQGTPPTEKEPAPAPTPTSTQASRTKARAPEEEDAQAQHPRKRRFQRSS ENSCPOP00000005852/1-2553 RNRAQMLASQSKQGTLPAEKEPTPTPTP----PSRAKARAPEEEDAQAQHPRKRRFQRSS ********.***** .:**: *:* :*:*.*..*::*************** ENSP00000367581/1-2663 QQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRANPYFEYLQIRKKIEEKRK ENSMUSP00000095938/1-2664 QQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRK ENSRNOP00000035742/1-2629 QQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRK XP_004842705.1/1-2514 QQLQQQLHTSTRQTREVIQQTLAAIVDAIKLDDIEPYHSDRSNPYFEYLQIRKKIEEKRK ENSCPOP00000005852/1-2553 QQLQQQLHTSTQQTREVIQQTLAAIVDAIKLDDIEPYHSDRSNPYFEYLQIRKKIEEKRK *******:***:******************** ********:****************** ENSP00000367581/1-2663 ILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRG ENSMUSP00000095938/1-2664 ILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRG ENSRNOP00000035742/1-2629 ILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRG XP_004842705.1/1-2514 ILCYITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRG ENSCPOP00000005852/1-2553 ILCYITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRG *** ************************************************:******* ENSP00000367581/1-2663 KLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQ-- ENSMUSP00000095938/1-2664 KLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQ-- ENSRNOP00000035742/1-2629 KLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQ-- XP_004842705.1/1-2514 KLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQVR ENSCPOP00000005852/1-2553 KLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQ-- ********************************************************** ENSP00000367581/1-2663 -GDENKSVRDRFNARQ-------------FISWLQDVDDKYDRMKTCLLMRQQHEAAALN ENSMUSP00000095938/1-2664 -GDENKSVRDRFNARQ-------------FISWLQDVDDKYDRMKTCLLMRQQHEAAALN ENSRNOP00000035742/1-2629 -GDENKSVRDRFNARQ-------------FISWLQDVDDKYDRMKTCLLMRQQHEAAALN XP_004842705.1/1-2514 GGPQGYSLALHLGSSHPHAPSTLSQLLTALCPWRATCLPAATEGAGAVALRGGHMHPAGN ENSCPOP00000005852/1-2553 -GDENKSVRDRFNARQ-------------FISWLQDVDDKYDRMKTCLLMRQQHEAAALN * :. *: ::.: : : .* . .: :* * .* * ENSP00000367581/1-2663 AV------------------QRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVD----VN ENSMUSP00000095938/1-2664 AV------------------QRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVD----VN ENSRNOP00000035742/1-2629 AV------------------QRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVD----VN XP_004842705.1/1-2514 SCPSSLTGQVRLHFPFPLPEEQWGWHTGGPGQQVVAATGPVVTGQAGAHLTQVDRGFSCG ENSCPOP00000005852/1-2553 AV------------------QRMEWQLKAQELDPAGHKTLCVNEVPSFYVPMVD----VN : :: *: : .. . *. .. ::. ** . ENSP00000367581/1-2663 DDFVLLPA ENSMUSP00000095938/1-2664 DDFVLLPA ENSRNOP00000035742/1-2629 DDFVLLPA XP_004842705.1/1-2514 NEGRSAAG ENSCPOP00000005852/1-2553 DDFVLLPA :: ..