CLUSTAL W(1.81) multiple sequence alignment ENSP00000332576/1-916 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP ENSMUSP00000068652/1-908 MGKAAALSRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSAFGSGPASKPQLQPVQAP ENSRNOP00000060468/1-896 MGKAAALSRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSTLGSGPAPKPQFQPVQAP ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 MGKAAAQSRSGGCGGRSRGLSSLFTVVPCLSCHTATPGMTAATSGCGLEPKPQPQLVPAP ENSP00000332576/1-916 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEP-GAGQPSELLQGSRPGSESSSGVGAGPF ENSMUSP00000068652/1-908 ERELLSKQVCQPISEPASRSEPGSQTTSVPRPSGVGQESELQ-GLWPGSENGTRSVSIIK ENSRNOP00000060468/1-896 ERELLSEQVCQPISEP--RSEPGSQTTFVPQPLGAGQESESL-GLWPGS--------GPN ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 ERESLSERVR--------RSEPGSETSPEPPP-GSGQETELL-GLGPRSELGPGAGPGSF ENSP00000332576/1-916 TKAASE---PLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAP ENSMUSP00000068652/1-908 ASPELAMPSPLQSTVGSLPVTKPESKLVP--KTQSFLRQGQAKISVGTPVSGIGV----Q ENSRNOP00000060468/1-896 TKASPELPSPPRSTAESLP--KPESKAGP--KTQSVLRPGQSKTSAGSPVSGTSV----P ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 SRDLAEHLAPLGSAVERESSLKPEFGSVP--KPLSLLRPGQAKTPLGVPVSGNSSISSDT ENSP00000332576/1-916 LALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHID ENSMUSP00000068652/1-908 MVSPPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFE ENSRNOP00000060468/1-896 MVSPPLDSYKGWLFKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLASAHFE ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 MVSFPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLATVQIG ENSP00000332576/1-916 TEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEAT-T ENSMUSP00000068652/1-908 TEDSCGILLCNGARTYHLKASSEVDRQHWITALELAKAKAIRVMKTQSDDSGDDDEEPAA ENSRNOP00000060468/1-896 TEDSCGILLCNGARTYHLKASSEVDRQQWITVLELAKAKAIRVMNTPTDDSGDDDEEPAA ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 TEDSCGILLISGARNYHLKSSSEVDRQQWITALELAKAKAVRMMNTHSDDSGDDDEGTAS ENSP00000332576/1-916 PADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNE ENSMUSP00000068652/1-908 PADNSELHHTLKTLSLKLNDLSTCNDLIAKHGAALQRSLNELDSLKIPSECGEKLKVVNE ENSRNOP00000060468/1-896 PADNSDLHHTLKTLSLKLDDLGTCNDLIAKHGAALQRSLNELDSLKIPSESGEKLKVVNE ENSCPOP00000005800/1-536 ------------------------------------------------------------ XP_004843519.1/1-909 PADKSELQHTLKNLTLKLDDLSTCSDLIAKHGAALQRSLNELDSLKIPPESGEKLKVVNE ENSP00000332576/1-916 RATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLER ENSMUSP00000068652/1-908 RATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLER ENSRNOP00000060468/1-896 RATLFRITSNAMINACKDFLELAEIHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLER ENSCPOP00000005800/1-536 --------------ACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLER XP_004843519.1/1-909 RATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLER **:******* *********:************************* ENSP00000332576/1-916 AFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRK ENSMUSP00000068652/1-908 AFCNTPGGPASSSKSFSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVVTEAKED-RK ENSRNOP00000060468/1-896 AFCNTPGGPASSSKSFSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVITEAKED-RK ENSCPOP00000005800/1-536 AFRSGPGWPANPSKSFSEGSFLTSKGEDSEEDEDTEYFDAMEDSTSFITVITEASED-RW XP_004843519.1/1-909 AFHSGPGWSANPSKSFSKGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITETNED-RK ** . ** .*..**** :**:**.***:**********************:**:.** * ENSP00000332576/1-916 AEGSTGT-SSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRE ENSMUSP00000068652/1-908 PESGPGT-TTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRE ENSRNOP00000060468/1-896 PEGGPGT-TSVDWTSADNVLDGASFMPKDSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRE ENSCPOP00000005800/1-536 PVGGIAL-GTVDWTTADSVSE-ASLVPKGSDKLKRRARIPDKPNYSLNLWSIMKNCIGRE XP_004843519.1/1-909 AEGGTSTCGTGDWTTADNVLDGASLVPKGSYKVKRRVRIPDKPNYSLNLWSIMKNCIGRE . .. . : **::**.* : **::**.* *:***.***:******************* ENSP00000332576/1-916 LSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHR ENSMUSP00000068652/1-908 LSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHR ENSRNOP00000060468/1-896 LSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHR ENSCPOP00000005800/1-536 LSKIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCSSSVEQMCLVAAFSVSSYSTTVHR XP_004843519.1/1-909 LSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCSSSVEQMCLVAAFSVSSYSTTVHR **:*******************************:*:*********************** ENSP00000332576/1-916 IAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFR ENSMUSP00000068652/1-908 IAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFR ENSRNOP00000060468/1-896 IAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFR ENSCPOP00000005800/1-536 IAKPFNPMLGETYELDRLEDMGLRSLCEQVSHHPPSAAHYAFSKNGWSLWQEITIASKFR XP_004843519.1/1-909 IAKPFNPMLGETFELDRLEDMGLRSLCEQVSHHPPSAAHYACSKHGWSLWQEITIASKFR ************:****::********************:. **:**********:**** ENSP00000332576/1-916 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQ ENSMUSP00000068652/1-908 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQ ENSRNOP00000060468/1-896 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQ ENSCPOP00000005800/1-536 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQ XP_004843519.1/1-909 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQ *******************************************************:**** ENSP00000332576/1-916 LKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQK ENSMUSP00000068652/1-908 LKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSS---DGRQK ENSRNOP00000060468/1-896 LKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVHSSPSS---DGKQK ENSCPOP00000005800/1-536 VKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKIVH--------DGKQK XP_004843519.1/1-909 LKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWNEQMECSKIVQSSPSSPGSDGKQK :**:********************************::******::: **:** ENSP00000332576/1-916 TVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRW ENSMUSP00000068652/1-908 TVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRW ENSRNOP00000060468/1-896 TVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEEGVAPTDSRLRPDQRLMERGRW ENSCPOP00000005800/1-536 TVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEPEGGVAPTDTRLRPDQRLMEEGCW XP_004843519.1/1-909 TVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNELEGGVAPTDSRLRPDQRLMEEGRW ******.*****:*********************** * ******:**********.* * ENSP00000332576/1-916 DEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMAC ENSMUSP00000068652/1-908 DEANTEKQRLEEKQRLSRRRRLESCTAG--CGGEEEKESDGYVPLWFEKRLDPLTGEMAC ENSRNOP00000060468/1-896 DEANTEKQRLEEKQRLNRRRRLESCTAG--CGGEEEKESDGYSPLWFEKRLDPLTGEMAC ENSCPOP00000005800/1-536 TGPPRRSSGWRRKQPLSRRRRLEICAPGR-SFATEEKESDGYAPLWFEKRLDPLTRETAY XP_004843519.1/1-909 DQANTEKQRLEEKQRLSRRRRLEICAPGRSCGAEEEKEADGYVPLWFEKRLDPLTRETAY . ... ..** *.****** * .* . . ****:*.* ************ * * ENSP00000332576/1-916 VYKGGYWEAKEKQDWHMCPNIF ENSMUSP00000068652/1-908 MYKGGYWEAKEKKDWHMCPNIF ENSRNOP00000060468/1-896 IYKGGYWEAKEKKDWHMCPNIF ENSCPOP00000005800/1-536 VYKGGYWEAKEKQDWHMCPNIF XP_004843519.1/1-909 VYKGGYWEAKEKQDWHMCPNIF :***********:*********