CLUSTAL W(1.81) multiple sequence alignment ENSP00000263088/1-933 MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFA ENSCPOP00000005695/1-936 MTATQGCPFPYGDYLDSSQLHMEPDEIDTLREGEDPADRMHPFLAVYDLQPLKMHPLVFA XP_004857340.1/1-936 MIATQECPFPYGDYLDSSQLHMEPDEVNTLREGEDPADRMHPFLAIYDLQPLKVHPLVFA ENSMUSP00000104197/1-944 MTVTQKNLFPYGDYLNSSQLHMEPDEVDTLREGEDPADRMHPYLAIYDLQPLKAHPLVFA ENSRNOP00000053831/1-935 MTVTQTDLFPYGDYLNSSQLHMEPDEVDTLKEGEDPADRMHPFLAIYDLQPLRAHPLVFA * .* ** ** *:****:**.**::**:***********:**:*:**.*: ****** ENSP00000263088/1-933 PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVL ENSCPOP00000005695/1-936 PGVPVIAQVVGTERYTSGSKVGTCTLYSVRLAHGDFTWTTKKKFRHFQELHRDLQRHKVL XP_004857340.1/1-936 PGVSVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVL ENSMUSP00000104197/1-944 PGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVL ENSRNOP00000053831/1-935 PGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVL ***.* *************************:****:******:********** ***** ENSP00000263088/1-933 MSLLPLARFAVAYSPARDA---GNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMS ENSCPOP00000005695/1-936 MSLLPLARFAVAYSPAREPADTANREMPPLPRGSPEGSARHAASKQKYLENYLNRLLTMS XP_004857340.1/1-936 MSLLPLARFAVAYSPAQEAADRANREMPSLPRGGPEGSTRHAASKQKYLENYLNHLLTMS ENSMUSP00000104197/1-944 MSLLPLARFAVTHSPAREA---AAEDIPSLPRGGSEGSARHTASKQKYLENYLNRLLTMS ENSRNOP00000053831/1-935 MSLLPLARFAAAHSPAREA---ANENIPSLPRGGSEGSARHTASKQKYLENYLNRLLTMS **********.::***::. . .::*.***...***:**:************:***** ENSP00000263088/1-933 FYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRW ENSCPOP00000005695/1-936 FYRNYHAMTEFLEVSQLSFIPDLGPKGLEGVIRKRSGGHRVPGLTCCGRDQVCYRWSKRW XP_004857340.1/1-936 FYRNYHAMTEFLEVSQLSFIPDLGPKGLEGVIRKRSGGHRLPGLTCCGRDQVCYRWSKRW ENSMUSP00000104197/1-944 FYRNYHAMTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVPGFTFCGRDQVCYRWSKRW ENSRNOP00000053831/1-935 FYRNYHAMTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVPGFTCCGRDQVCYRWSKRW ************************ *****:*********:**:* ************** ENSP00000263088/1-933 LVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYR ENSCPOP00000005695/1-936 LVVKDSFLLYMCLETGVISFVQLFDPGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYR XP_004857340.1/1-936 LVVKDSFLLYMCLETGVISFVQLFDSGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYR ENSMUSP00000104197/1-944 LVVKDSFLLYMRPETGAISFVQLFDPGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYR ENSRNOP00000053831/1-935 LVVKDSFLLYMRPETGAISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYR *********** ***.********.************:*:******************* ENSP00000263088/1-933 QARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQE ENSCPOP00000005695/1-936 QARWWAQEIAELARGPGRDFLQLHRHESYAPPRPRTLARWFVNGAGYFAAVADAILRARE XP_004857340.1/1-936 QARWWGQEITELAQGPGKDFLRLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRARE ENSMUSP00000104197/1-944 QARWWGQEITELAQGSGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQE ENSRNOP00000053831/1-935 QARWWGQEITELAQGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRARE *****.***:***:*.*:***:**:*:******* ***********************:* ENSP00000263088/1-933 EIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSK ENSCPOP00000005695/1-936 EIFITDWWLSPEVYLKRPAHSDDWRLDFMLKKAAEEGVRVSVLLFKEVELALGINSGYSK XP_004857340.1/1-936 EIFITDWWLSPEVYLKRPAHSDDWRLDIMLKKAAEEGVRVSVLLFKEVELALGINSGYSK ENSMUSP00000104197/1-944 EIFITDWWLSPEIYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSK ENSRNOP00000053831/1-935 EIFITDWWLSPEIYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSK ************:**************:***: ********:****************** ENSP00000263088/1-933 RALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGD ENSCPOP00000005695/1-936 RTLMLLHPLLQVMRHPDQMTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDLHYRLTDLAD XP_004857340.1/1-936 RTLMLLHPNIKVMRHPDQMTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDLHYRLTDLGD ENSMUSP00000104197/1-944 RTLMLLHPNIKVMRHPDLVTLWAHHEKLLVVDQVVAFLGGLDLAFGRWDDVQYRLTDLGD ENSRNOP00000053831/1-935 RTLMLLHPNIKVMRHPDLVTLWAHHEKLLVVDQAVAFLGGLDLAYGRWVLPEPRTTTPGG *:****** ::****** :**************.**********:*** . * * .. ENSP00000263088/1-933 SSE---SAASQPPTPRPDSPATPDLS-HNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRE ENSCPOP00000005695/1-936 SSG---SGASQPPAECPDPEAAPDLS-HNQLFWLGKDYSNLIAKDWVQLDRPFEDFIDRE XP_004857340.1/1-936 SSE---SGASQTPTPCTDSAATPDLS-HNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRE ENSMUSP00000104197/1-944 PSE---PVHLQTPTLGSDPAATPDLS-HNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRE ENSRNOP00000053831/1-935 PPTVGWALPHQSLTINKCLSRLPNLILHKTRLATSILKTPALTSPLTLLG--FPDFIDRE .. . *. : *:* *: : . : ::. . *. * ****** ENSP00000263088/1-933 TTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLP ENSCPOP00000005695/1-936 TTPRMPWRDVGVVVHGPAARDLARHFIQRWNFTKTTKAKYKTPAYPYLLPKSISTVNQLP XP_004857340.1/1-936 TTPRMPWRDVGVVVHGLAARDLARHFIQRWNFTKTTKAKYKTPMYPYLLPKSTSTANQLP ENSMUSP00000104197/1-944 TTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTTKARYKTPLYPYLLPKSTSTANNLP ENSRNOP00000053831/1-935 TTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTIKARYKIPQYPYLLPKSASTANHLP **************** .***************** **:** * ******** **.*:** ENSP00000263088/1-933 FTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTV ENSCPOP00000005695/1-936 FTLPGVQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESKHFLYIENQFFISCSDGRTV XP_004857340.1/1-936 FTIPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESKHFLYIENQFFISCSDGRTV ENSMUSP00000104197/1-944 FMIPGGQCATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTV ENSRNOP00000053831/1-935 FIIPGAQCATVQVLRSVDRWSAGTLESSILNAYLHTIRESQHFLYIENQFFISCSDGRTV * :** **:*****************.*************:******************* ENSP00000263088/1-933 LNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTY------ ENSCPOP00000005695/1-936 LNKVGDEIVERILKAHKQGQCFRVYVLLPLLPGFEGDITTGGGNSIQAILHFTY------ XP_004857340.1/1-936 LNKVGDEIVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTY------ ENSMUSP00000104197/1-944 LNKVGDEIVDRILKAHEQGQCFRVYLLLPLLPGFEGDISTGGGNSIQAILHFTYSLCLLH ENSRNOP00000053831/1-935 LNKVGDEIVDRILKAHEQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTY------ *********:******:** *:***:************:*************** ENSP00000263088/1-933 -----RTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIA ENSCPOP00000005695/1-936 -----RTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPVSELIYIHSKMLIA XP_004857340.1/1-936 -----RTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPVSELIYIHSKMLIA ENSMUSP00000104197/1-944 PFFSLRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPISELIYIHSKMLIA ENSRNOP00000053831/1-935 -----RTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPISELIYIHSKLLIA *******:*****************:***************:*********:*** ENSP00000263088/1-933 DDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGV ENSCPOP00000005695/1-936 DDRTVIIGSANINDRSLLGKRDSELAVLIEDTEMVSSLMDGAEYQAGRFALSLRKHCFSV XP_004857340.1/1-936 DDRTVIIGSANINDRSLLGKRDSELAVLIEDTEMVPSLMDGMEYQAGRFALSLRKHCFSV ENSMUSP00000104197/1-944 DDRTVIIGSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRKHCFSV ENSRNOP00000053831/1-935 DDRTVIIGSANINDRSLLGKRDSELAILIEDTEMEPSLMDGVEYQAGRFALSLRKHCFSV **************************:**:*** .***:* ****************.* ENSP00000263088/1-933 ILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVE ENSCPOP00000005695/1-936 ILGANARPDLDLRDPVCDDFFQLWQDTAEKNATIYEQIFRCLPSNATRSLRTLREYVAVK XP_004857340.1/1-936 ILGANAWPDLDLQDPVCDDFFQLWQETAENNANIYEQIFRCLPSNATRSLRTLREYVAVE ENSMUSP00000104197/1-944 ILGANTWPDLDLRDPVCDDFFQLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVE ENSRNOP00000053831/1-935 ILGANTWPDLDLRDPVCDDFFQLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVE *****: *****:**:*********: **.**.******************:*******: ENSP00000263088/1-933 PLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT ENSCPOP00000005695/1-936 PLAVVSPPLACSELTEVKGHLVHFPLKFLEEESLLPPLGSKEGMVPLEVWT XP_004857340.1/1-936 PLAVVSPPLARSELTEIQGHLVHFPLKFLEDESLLPSLGSKEGMIPLEVWI ENSMUSP00000104197/1-944 SLATVSPSLAQSELAHIQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT ENSRNOP00000053831/1-935 SLATVSPSLAQSELAHIRGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT .**.***.** ***:.::************:*****.*******:*****