CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000090593/1-1353 MVIKTDELPAAAPADSAREHGSQAGGKGRPNAADLPSVMLLNGDCSENLKKEEGTSEPPR ENSRNOP00000003687/1-1349 MVIKTDELPAAAPADSAREHGSQAGGKGRPNAADPPSVMLLNGDCSENLKKEEGSSEPPR ENSP00000458986/1-1309 --------------------------------------MLLNGDCPESLKKEAAAAEPPR ENSCPOP00000005594/1-1347 MVIKTDELPAAAPVDSAREHSSQAGGKGRPAASDPPSVMLLNGDCPESL-KEEGVADLPK XP_004857248.1/1-1348 MVIKTDELPAAARADSTREHGSQAGGKGRPGAADPSSVMLLNGDCPESLKKEEGAANPPK *******.*.* ** . :: *: ENSMUSP00000090593/1-1353 ENGLDEGEPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDRED ENSRNOP00000003687/1-1349 ENGLDEGEPGEETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDRED ENSP00000458986/1-1309 ENGLDEAGPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDRED ENSCPOP00000005594/1-1347 ENGQDEGEPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDRED XP_004857248.1/1-1348 ENGLDEGEPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDRED *** **. **:************************************************* ENSMUSP00000090593/1-1353 TCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSL ENSRNOP00000003687/1-1349 TCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSL ENSP00000458986/1-1309 TCHRTCFSLHLDGNVLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSL ENSCPOP00000005594/1-1347 TCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSL XP_004857248.1/1-1348 TCHRTCFSLHLDSNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSL ************.*:********************************************* ENSMUSP00000090593/1-1353 DPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPL ENSRNOP00000003687/1-1349 DPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPL ENSP00000458986/1-1309 DPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPL ENSCPOP00000005594/1-1347 DPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPL XP_004857248.1/1-1348 DPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPL ************************************************************ ENSMUSP00000090593/1-1353 QPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQ ENSRNOP00000003687/1-1349 QPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSVTASTRGFYLNQ ENSP00000458986/1-1309 QPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQ ENSCPOP00000005594/1-1347 QPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQ XP_004857248.1/1-1348 QPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQ ************************************************:*********** ENSMUSP00000090593/1-1353 STAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSW ENSRNOP00000003687/1-1349 STAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSW ENSP00000458986/1-1309 STAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSW ENSCPOP00000005594/1-1347 STAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSW XP_004857248.1/1-1348 STAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSW ************************************************************ ENSMUSP00000090593/1-1353 TAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI ENSRNOP00000003687/1-1349 TAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI ENSP00000458986/1-1309 TAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI ENSCPOP00000005594/1-1347 TAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI XP_004857248.1/1-1348 TAPQAEHAIDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAI ********:*************************************************** ENSMUSP00000090593/1-1353 FKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGD ENSRNOP00000003687/1-1349 FKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGD ENSP00000458986/1-1309 FKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGD ENSCPOP00000005594/1-1347 FKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGD XP_004857248.1/1-1348 FKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGD ************************************************************ ENSMUSP00000090593/1-1353 VAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIY ENSRNOP00000003687/1-1349 VAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIY ENSP00000458986/1-1309 VAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIY ENSCPOP00000005594/1-1347 VAAYVAPSNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIY XP_004857248.1/1-1348 VAAYVAPTNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIY *******:**************************************************** ENSMUSP00000090593/1-1353 GSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHY ENSRNOP00000003687/1-1349 GSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHY ENSP00000458986/1-1309 GSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRDEEVELCSSVECKGIIGNDGRHY ENSCPOP00000005594/1-1347 GSIDFGKTVVTHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHY XP_004857248.1/1-1348 GSIDFGKTVVTHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHY **********:********************:**************************** ENSMUSP00000090593/1-1353 ILDLLRTFPPDLNFLPVPGEELPEECSRAGFPRTHRHKLCCLRQELVDAFVEHRYLLFMK ENSRNOP00000003687/1-1349 ILDLLRTFPPDLNFLPVPGEELPEECSRAGFPRTHRHKLCCLRQELVDAFVEHRYLLFMK ENSP00000458986/1-1309 ILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMK ENSCPOP00000005594/1-1347 ILDLLRTFPPDLNFLPVPGEELPEECTRAGFPRTHRHKLCCLRQELVDAFVEHRYLLFMK XP_004857248.1/1-1348 ILDLLRTFPPDLNFLPVPGEELPEECARAGFPRTHRHKLCCLRQELVDAFVEHRYLLFMK **************************:******:************************** ENSMUSP00000090593/1-1353 LAALQLMQQKASKVETTTSLENGGLPSSAETKSEDSIGPEAGCEEEGSSVSGLAKVKELA ENSRNOP00000003687/1-1349 LAALQLMQQKASKVDTSTSLENGGPPSSTETKSEDSLGSEAGCEEEGSSVSGLAKVKELA ENSP00000458986/1-1309 LAALQLMQQNASQLETPSSLENGGPSSL-ESKSEDPPGQEAGSEEEGSSASGLAKVKELA ENSCPOP00000005594/1-1347 LAALQLMQQKASKVET-TSLENGSPSSS-ESKPADPLGPEAGNEEEGSSASGLAKVKELA XP_004857248.1/1-1348 LAALQLMQQKANKVETSTSLENGSPPSP-ESKPEDPLGPEAGSEEEGSSASGLAKVKELA *********:*.:::* :*****. .* *:*. *. * *** ******.********** ENSMUSP00000090593/1-1353 ETIASDDGTVDPRSREVIRNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQK ENSRNOP00000003687/1-1349 ETIASDDGTVDPRSREVIQNACKAVGSVSSTAFDIRFNPDIFSPGVRFPESCQDEVRDQK ENSP00000458986/1-1309 ETIAADDGT-DPRSREVIRNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQK ENSCPOP00000005594/1-1347 ETIASDDSTADPRSREVIHNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQK XP_004857248.1/1-1348 ETIASDDST-DPRSREVIRNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQK ****:**.* ********:********:******************************** ENSMUSP00000090593/1-1353 QLLKDAAAFLLSCQIPGLVKDCTEYAVLPMDGATLAEVMRQRGINMRYLGKVLDLVLRSP ENSRNOP00000003687/1-1349 QLLKDAAAFLLSCQIPGLVKDCTEYAVLPMDGATLAEVMRQRGINMRYLGKVLDLVLRSP ENSP00000458986/1-1309 QLLKDAAAFLLSCQIPGLVKDCMEHAVLPVDGATLAEVMRQRGINMRYLGKVLELVLRSP ENSCPOP00000005594/1-1347 QLLKDAAAFLLSCQIPGLVKDCAEHVVLPVDGATLAEAMRQRGINMRYLGKVLDLVLRSP XP_004857248.1/1-1348 QLLKDAAAFLLSCQIPGLVKDCAEHAVLPVDGATLAEAMRQRGINMRYLGKVLDLVLRSP ********************** *:.***:*******.***************:****** ENSMUSP00000090593/1-1353 ARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLP ENSRNOP00000003687/1-1349 ARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLP ENSP00000458986/1-1309 ARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLP ENSCPOP00000005594/1-1347 ARSQLDHVHKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLP XP_004857248.1/1-1348 ARDQLDHVHKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLP ** ****:.*************************************************** ENSMUSP00000090593/1-1353 ADELLSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICHEAKNYFDFTLECDSVDQAVE ENSRNOP00000003687/1-1349 ADELLSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFTLECDSVDQAVE ENSP00000458986/1-1309 ADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFDLECETVDQAVE ENSCPOP00000005594/1-1347 ADELLSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFSLECDSVDQAVE XP_004857248.1/1-1348 ADELLSKKRNKRRKNRPPGAPDNTAWAVMTPQELWKNICQEAKNYFDFSLECDSVDQAVE ****:***************.******************:******** ***::****** ENSMUSP00000090593/1-1353 TYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFH ENSRNOP00000003687/1-1349 TYGLQKITLLREISLKTGMQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFH ENSP00000458986/1-1309 TYGLQKITLLREISLKTGIQVLLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFH ENSCPOP00000005594/1-1347 AYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFH XP_004857248.1/1-1348 TYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFH :*****************:*:*************************************** ENSMUSP00000090593/1-1353 FFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEAL ENSRNOP00000003687/1-1349 FFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEAL ENSP00000458986/1-1309 FFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEAL ENSCPOP00000005594/1-1347 FFQSGQAKVQQGFLKEGCELISEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEAL XP_004857248.1/1-1348 FFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEAL *********************.**************** ********************* ENSMUSP00000090593/1-1353 SNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH ENSRNOP00000003687/1-1349 SNQQKAVLMSERVVGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH ENSP00000458986/1-1309 SNQQKAVLMSERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH ENSCPOP00000005594/1-1347 SNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH XP_004857248.1/1-1348 SNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH *************:* ******************************************** ENSMUSP00000090593/1-1353 PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVTTKYHGPKALKVALSHHLVARVYESKA ENSRNOP00000003687/1-1349 PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVTTKYHGPKALKVALSHHLVARVYESKA ENSP00000458986/1-1309 PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKA ENSCPOP00000005594/1-1347 PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKA XP_004857248.1/1-1348 PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKA *********************************:************************** ENSMUSP00000090593/1-1353 EFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANI ENSRNOP00000003687/1-1349 EFRSALQHEKEGYTIYKTQLGEDHEKTRESSEYLKCLTQQAVALQRTMNEIYRNGSSANI ENSP00000458986/1-1309 EFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANI ENSCPOP00000005594/1-1347 EFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANI XP_004857248.1/1-1348 EFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANI ***************************:******************************** ENSMUSP00000090593/1-1353 PPLKFTAPSMTSVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEANRNRDKAEEQP ENSRNOP00000003687/1-1349 PPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDKAEE-P ENSP00000458986/1-1309 PPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEE-P ENSCPOP00000005594/1-1347 PPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEANKNRDKIEE-P XP_004857248.1/1-1348 PPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASKNRDKAEE-P **********:**************************************.:***: ** * ENSMUSP00000090593/1-1353 MAPEPEPEPERAVEDMGSPQTAKEGPSSLNLQG ENSRNOP00000003687/1-1349 MATE--PEPDRALEGMGSPQTAKEGP-SLSLQG ENSP00000458986/1-1309 MATE--PAPAGAPGDLGSQPPAAKDP-SPSVQG ENSCPOP00000005594/1-1347 MATE--PEPVRAPEDLGSQPQAAKDPSSPSLQG XP_004857248.1/1-1348 TATE--PEPAGAPEDLGSQPQAPKDPSSPSLQG *.* * * * .:** * :.* * .:**