CLUSTAL W(1.81) multiple sequence alignment ENSP00000393527/1-725 ------------------------XTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTL ENSMUSP00000005651/1-678 MGDSHEDTSATVPEAVAEEVSLFSTTDIVLFSLIVGVLTYWFIFKKKKEEIPEFSKIQTT ENSRNOP00000001961/1-678 MGDSHEDTSATMPEAVAEEVSLFSTTDMVLFSLIVGVLTYWFIFRKKKEEIPEFSKIQTT ENSCPOP00000005592/1-677 MGDSHVDTGATSTEAVAEEVSLFSMTDMILLSVLVGFLTYFFLFRKKKEEIPEFTKISTT XP_004840142.1/1-678 MGDSHMDTGATNAEAVAEEVSLFSTTDMIVFSVIIGVLTYWFLFRKKKEEMPEFTKISTT **::::*:::*.***:*:*:*****:***:**.* ENSP00000393527/1-725 TSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLA ENSMUSP00000005651/1-678 APPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLA ENSRNOP00000001961/1-678 APPVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLA ENSCPOP00000005592/1-677 TSSVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMAADPEEYDLA XP_004840142.1/1-678 TTSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMAADPEEYDLA :..*:*********************************************:********* ENSP00000393527/1-725 DLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVSHPETAMGSR ENSMUSP00000005651/1-678 DLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFA----------- ENSRNOP00000001961/1-678 DLSSLPEIDKSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLTGVKFA----------- ENSCPOP00000005592/1-677 DLSSLPEIDNSLAVFCMATYGEGDPTDTP-GLYDWLQETDLDLSGVKYA----------- XP_004840142.1/1-678 DLSSLAEIDNSLVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGIKYA----------- *****.***::*.**************.. .:********:**:*:*:* ENSP00000393527/1-725 WPAVPPWGLQIHVSERQPSRPPPCPQQPGQATCETLSSAPDPSTTRMSPPCPQPQSAPGG ENSMUSP00000005651/1-678 ------------------------------------------------------------ ENSRNOP00000001961/1-678 ------------------------------------------------------------ ENSCPOP00000005592/1-677 ------------------------------------------------------------ XP_004840142.1/1-678 ------------------------------------------------------------ ENSP00000393527/1-725 IGCWRLKVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQ ENSMUSP00000005651/1-678 -------VFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQ ENSRNOP00000001961/1-678 -------VFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQ ENSCPOP00000005592/1-677 -------VFGLGNKTYEHFNSMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQ XP_004840142.1/1-678 -------VFGLGNKTYEHFNAMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQ *************:******:******************************** ENSP00000393527/1-725 FWPAVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPF ENSMUSP00000005651/1-678 FWPAVCEFFGVEATGEESSIRQYELVVHEDMDTAKVYTGEMGRLKSYENQKPPFDAKNPF ENSRNOP00000001961/1-678 FWPAVCEFFGVEATGEESSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPF ENSCPOP00000005592/1-677 FWPAVCEFFGVEATGEESSIRQYELVLHADTDPAKVYTGEMGRLKSYENQKPPFDAKNPF XP_004840142.1/1-678 FWPAVCEFFGVEATGEESSIRQYELVVHMDIDEARVYTGEMGRLKSYENQKPPFDAKNPF *******.******************:* * * *:** ********************** ENSP00000393527/1-725 LAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADL ENSMUSP00000005651/1-678 LAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSTLVNQIGEILGADL ENSRNOP00000001961/1-678 LAAVTANRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADL ENSCPOP00000005592/1-677 LAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSNLVNQLGKILGADL XP_004840142.1/1-678 LAAVTTNRKLNQGTERYLMHLELDISDSKIRYESGDHVAIYPANDSNLVNQLGKILGADL *****:**********:**********************:****** ****:*:****** ENSP00000393527/1-725 DVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELL ENSMUSP00000005651/1-678 DVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHL ENSRNOP00000001961/1-678 DVIMSLNNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHL ENSCPOP00000005592/1-677 DVVMSLKNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEQL XP_004840142.1/1-678 DVVMSLKNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEQL **:***:****************:********************************** * ENSP00000393527/1-725 RKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSS ENSMUSP00000005651/1-678 HKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSS ENSRNOP00000001961/1-678 HKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSS ENSCPOP00000005592/1-677 HKMASSSGEGKELYLTWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSS XP_004840142.1/1-678 RKMASSSGEGKELYLSWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSS :**************:*************** **************************** ENSP00000393527/1-725 KVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPF ENSMUSP00000005651/1-678 KVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRTKEPAGENGRRALVPMFVRKSQFRLPF ENSRNOP00000001961/1-678 KVHPNSVHICAVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPF ENSCPOP00000005592/1-677 KVHPNSVHICAVVVEYETKSGRINKGVATSWLQAKDPAGENGRRALVPMFVRKSQFRLPF XP_004840142.1/1-678 KVHPNSVHICAVVVEYETKSGRINKGVATSWLQAKNPAGDNGRRALVPMFVRKSQFRLPF ************.****:*:**:******.**::*:***:** ***************** ENSP00000393527/1-725 KATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQF ENSMUSP00000005651/1-678 KPTTPVIMVGPGTGVAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARF ENSRNOP00000001961/1-678 KSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARF ENSCPOP00000005592/1-677 KSTTPVIMVGPGTGVAPFIGFIQERAWLQQQGKEVGETLLYYGCRRSDEDYLYREELAQF XP_004840142.1/1-678 KSTTPVIMVGPGTGVAPFMGFIQERAWLQQQGKEVGETLLYYGCRRSDEDYLYREELAQF *.************:***:*********::****************************:* ENSP00000393527/1-725 HRDGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLI-EGGAHIYVCGTPSSCP----- ENSMUSP00000005651/1-678 HKDGALTQLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMAKDVQN ENSRNOP00000001961/1-678 HKDGALTQLNVAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQN ENSCPOP00000005592/1-677 HKDGTLTQLNVAFSREQAQKVYVQHLLKRDQEHLWKLIHEDGAHIYVCGDARNMARDVQN XP_004840142.1/1-678 HKEGALSGLNVAFSREQAHKVYVQHLLKRDKEHLWKLIHEGGAHIYVCGDARNMARDVQN *::*:*: *********::*********:*:******* *.******** . . . ENSP00000393527/1-725 ---GMHGTWPGMCRTPST---TSWLSSGPWSTRRRWTTSRN ENSMUSP00000005651/1-678 TFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSL-DVWS---- ENSRNOP00000001961/1-678 TFYDIVAEFGPMEHTQAVDYVKKLMTKGRYSL-DVWS---- ENSCPOP00000005592/1-677 TFCNIAAELGGMEHTQAVDYVKKLMTKGRYSL-DVWS---- XP_004840142.1/1-678 TFCDIAAELGAMEHAQAVEYIKKLMTKGRYSL-DVWS---- .: . * :: :. .. ::.* :* *: