CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000137933/1-1429 MTLSTLAGERKALPASTCSLGGPD---------------------MIPYFSANAVISQ-N ENSRNOP00000019410/1-1430 MTLSTLADERKAPPASTCSLGGPD---------------------MIPYFSANAVISQ-N ENSP00000444743/1-1450 MALVTV--QRSPTPSTTSSPCASSSHLEDSESAALLCCECEESEIFTDSNEADSGEEECR ENSCPOP00000005164/1-1417 MALVTV--QRSPTPSTTSSPCAS---------------------------EADSGEEECR XP_004857133.1/1-1410 MALVTV--QRSPTPSTTSSPCAS---------------------------EADSGEEECR *:* *: :*.. *::*.* .. .*:: .: . ENSMUSP00000137933/1-1429 AINQLISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIR ENSRNOP00000019410/1-1430 AINQLISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR ENSP00000444743/1-1450 SQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR ENSCPOP00000005164/1-1417 SQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR XP_004857133.1/1-1410 SQPRSISESFLTVKGAALFLPRGNGSSTPRISHRRNKHAGDLQQHLQAMFILLRPEDNIR : : *************************:***************************** ENSMUSP00000137933/1-1429 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSND-STCTMGLVLPLWSDTLIH ENSRNOP00000019410/1-1430 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH ENSP00000444743/1-1450 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH ENSCPOP00000005164/1-1417 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH XP_004857133.1/1-1410 LAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIH ***************************************** ****************** ENSMUSP00000137933/1-1429 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYES ENSRNOP00000019410/1-1430 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYES ENSP00000444743/1-1450 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARAHNYYPGSLFLTWVSYYES ENSCPOP00000005164/1-1417 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARIHNYYPGSLFLTWVSYYES XP_004857133.1/1-1410 LDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYES ***************************************** ****************** ENSMUSP00000137933/1-1429 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT ENSRNOP00000019410/1-1430 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT ENSP00000444743/1-1450 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT ENSCPOP00000005164/1-1417 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT XP_004857133.1/1-1410 HINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTKLREIMMQKDLENIT ************************************************************ ENSMUSP00000137933/1-1429 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN ENSRNOP00000019410/1-1430 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN ENSP00000444743/1-1450 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN ENSCPOP00000005164/1-1417 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN XP_004857133.1/1-1410 SKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQN ************************************************************ ENSMUSP00000137933/1-1429 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH ENSRNOP00000019410/1-1430 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH ENSP00000444743/1-1450 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH ENSCPOP00000005164/1-1417 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH XP_004857133.1/1-1410 RGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVH ************************************************************ ENSMUSP00000137933/1-1429 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ ENSRNOP00000019410/1-1430 CKMGVSRSASTVIAYAMKEYGWNLDRAYEYVKERRTVTKPNPSFMRQLEEYQGILLASKQ ENSP00000444743/1-1450 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ ENSCPOP00000005164/1-1417 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ XP_004857133.1/1-1410 CKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQ ****************************:******************************* ENSMUSP00000137933/1-1429 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKEMTTSADQIAEVKTVENLAAMPTVFMEHV ENSRNOP00000019410/1-1430 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKEMTTSADQITEVKTVESLAAMPPVFMEHV ENSP00000444743/1-1450 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKDITTSADQIAEVKTMESHPPIPPVFVEHM ENSCPOP00000005164/1-1417 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPSIPPVFVEHV XP_004857133.1/1-1410 RHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTLESNPSIPPVFVEHV *******************************::*******:****:*. ..:*.**:**: ENSMUSP00000137933/1-1429 VPQDANQKGLHTKERVICLEFSSQEFRAGQIEDELNLNDINGCSSGCCLSESKLPLDNCH ENSRNOP00000019410/1-1430 VPQDVNQKGLRTKERVICLEFSSQEFHAGQIEDELNLNDINGCSSGCCLSESKFPLDNCH ENSP00000444743/1-1450 VPQDANQKGLCTKERMICLEFTSREFHAGQIEDELNLNDINGCSSGCCLNESKFPLDNCH ENSCPOP00000005164/1-1417 VPQDTNQKALCTKERMICLEFTSREFHTGQIEDELNLNDINGCSSGFCLTESKFPLDNCH XP_004857133.1/1-1410 VPQD-------TKERMICLEFTSREFHAGQIEDELNLNDINGCSSGFCLNESKFPLDNCH **** ****:*****:*:**::****************** **.***:****** ENSMUSP00000137933/1-1429 ASKALLQPGQAPDIANKFPDLAVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDLES ENSRNOP00000019410/1-1430 ASKALLQPGQAPDIANKFPDLAVEDLETDALKADVRVHLLPMEELTSRLKDLPMSPDLES ENSP00000444743/1-1450 ASKALIQPGHVPEMANKFPDLTVEDLETDALKADMNVHLLPMEELTSPLKDPPMSPDPES ENSCPOP00000005164/1-1417 ASKALIQPAQVPEMTNKFPDLTVEDLETDALKADINVHLLPMEELTSGLKDLPMSPDPES XP_004857133.1/1-1410 ASKALIQPGQVPEMANKFPDLTVEDLETDALKADINVHLLPMEELTSGLKDLPMSPDPES *****:**.:.*:::******:************:.*********** *** ***** ** ENSMUSP00000137933/1-1429 PSPQASCQAAISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRIEELGGGRSEGCRLSV ENSRNOP00000019410/1-1430 PSPQAGCQAAISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRIEELGGGRSEGCRLSV ENSP00000444743/1-1450 PSPQPSCQTEISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRMEELGGGRNESCRLSV ENSCPOP00000005164/1-1417 PSPQPSCHAEISDFSTDRIDFFSALEKFVELSQETGSRSFSHSRMEELSGGRSEGCRLSV XP_004857133.1/1-1410 PSPQPSCQAEISDFSTDRIDFFSALEKFVELSQETRSRSFSHSRMEELGGGRSESCRLSV ****..*:: ************************* ********:***.***.*.***** ENSMUSP00000137933/1-1429 IEVAASEMAADDQRSSSLSNTPHASEESSVDEDQSKAITELVSPDIIMQSHSENAISVKE ENSRNOP00000019410/1-1430 MEMAPSEMVTDDQRSSSLSDTPHASEESSVDEDQPKAVSELVSPDIIMQSHSENAISVKE ENSP00000444743/1-1450 VEVAPSKVTADDQRSSSLSNTPHASEESSMDEEQSKAISELVSPDIFMQSHSENAISVKE ENSCPOP00000005164/1-1417 VEVPSSEVTTDDQRSSSLSNTPHASEESSMDEEQSKAISELVSPDIFMHSHSENAISVKE XP_004857133.1/1-1410 VEVPPSEATTDDQRSSSLSNTPHASEESSMDEEQSKAISELISPDIFIHSHSENSISVKE :*:..*: .:*********:*********:**:*.**::**:****:::*****:***** ENSMUSP00000137933/1-1429 IVTEIESISQGVGQVQLKGDILSNPCHTPKKSTIHELPLERVPAPESKPGHWEQDESFCS ENSRNOP00000019410/1-1430 IVTEIESISQGVGQVQLKGDILSNPCHTPKKNIIHELPLERVQGPENKPGHLEQDESFCS ENSP00000444743/1-1450 IVTEIESISQGVGQIQLKGDILPNPCHTPKKNSIHELLLERAQTPENKPGHMEQDEDSCT ENSCPOP00000005164/1-1417 IVTEIESISQGVGQMQLKGDMLSNPCHTPKKSTTHELSLERAQAPENKAGHMEQDEVFCT XP_004857133.1/1-1410 IVTEIESISQGVGQMQLKGDMVSNPCHTPKKSTIHELSLERTQAPENKPGHMEQDEGFCP **************:*****::.********. *** ***. **.*.** **** *. ENSMUSP00000137933/1-1429 VQPELARDSGKCAPEEGCLTTHSSTADLEEEEPVEGEHD-WGPGMHSGAKWCPGSVRRAT ENSRNOP00000019410/1-1430 VQLELARDSGKCAPEEGCLATLSSTGDLEEEEPVEGEHD-WGPGTHPGAKWCPGSVRRAT ENSP00000444743/1-1450 AQPELAKDSGMCNP-EGCLTTHSSIADLEEGEPAEGEQELQGSGMHPGAKWYPGSVRRAT ENSCPOP00000005164/1-1417 AHPELPRDSGKCNP-EGCVTTQSSTIDFEEEEPTEGEHELWGSGMHSGANWYPGSVRRAT XP_004857133.1/1-1410 AQPELAKDSGKCNP-EDCLTTHSSTVDLEEEEPTEGEHELWGPGMHSGAKWCPGSVRRAT .: **.:*** * * *.*::* ** *:** **.***:: *.* *.**:* ******** ENSMUSP00000137933/1-1429 LEFEERLRQEQENHGTASAGPTLSNRKNSKNDSSVADLMPKWKSDETTPEHSFFLKEAEP ENSRNOP00000019410/1-1430 LEFEERLRQEQENHGTASPGPTLSNRKNSKNDSSVADLMPKWKSDETASEHSLSPKEAEP ENSP00000444743/1-1450 LEFEERLRQEQEHHGAAPTCTSLSTRKNSKNDSSVADLAPKGKSDEAPPEHSFVLKEPEM ENSCPOP00000005164/1-1417 LEFEERLRQEQEHHSPAPVGTSLSTRKNSKNDASGADLAPKGKNDEATSEYSFAPKEPEV XP_004857133.1/1-1410 LEFEERLRQEQDHHSPAPVCTSMSTRKNSKNDSSVADLAPKGKNDEAT-EYSFAPKEPEV ***********::*..*. .::*.*******:* *** ** *.**:. *:*: **.* ENSMUSP00000137933/1-1429 SKGKGKCSGSEAGSLSHCERNPTMPDCELLEHHSLPAPQDCLGSDSRSKKQEGDLKKQRA ENSRNOP00000019410/1-1430 GKGKGKCSGSEAGPLSHCEHNPAAAAPQLLEHHPSPAPQDCLGSESRSEKQEEDLRKQRT ENSP00000444743/1-1450 SKGKGKYSGSEAGSLSHSEQNATVPAPRVLEFDHLPDPQEGPGSDTGT-QQEGVLKDLRT ENSCPOP00000005164/1-1417 SKGKGKCSKSEAGSLSQCEQNAIVPALELLECHPLTATQDNPGSDIRT-KQ-GVPEEQRT XP_004857133.1/1-1410 SKGKGKCSKSEAGSLSQCEQNATVPALELLEYHPLAATQEYPRLDIRT-KQ-GVPEEQGT .***** * ****.**:.*:*. . .:** . . .*: : : :* .. : ENSMUSP00000137933/1-1429 VVPNQECDTQAILLPLPKKIEIIEYTPTVTSLGHTEPGGEATPSKEGEKQGLRKVKMEQS ENSRNOP00000019410/1-1430 VVSNQECETQAALLPLPKKIEIIEYTPTVTSLDHTEPGGETTPSKESEKQELRKVKMERS ENSP00000444743/1-1450 VIPYQESETQAVPLPLPKRVEIIEYTHIVTSPNHTGPGSEIATSEKSGEQGLRKVNMEKS ENSCPOP00000005164/1-1417 VVSCQGSEMQA--LTLPKRIEIIEYTHTVTSLSHTGSEAETATSEEKGEQGLRKVRVEKS XP_004857133.1/1-1410 VVPCQGSETQD--ILLPKRIEIIEYTHTVTSLSHTGSGGERATSKEKGDQGLRKVKVEKS *:. * .: * : ***::****** *** .** . .* :.*:: .* ****.:*:* ENSMUSP00000137933/1-1429 ITMFCALDENLNRTLEPSQVSLHPQVLPLPH-SSSECDRPAD-PNPMLSSPQDKGDCPST ENSRNOP00000019410/1-1430 ITMFCTLDENLNRTLDPSQVSLRPQVLPLPH-SSSEYDRLTD-PTPMLSSPQDKGDSPST ENSP00000444743/1-1450 VTVLCTLDENLNRTLDPNQVSLHPQVLPLPHSSSPEHNRPTDHPTSILSSPEDRGSSLST ENSCPOP00000005164/1-1417 VTMLCVLDENLNRTLDPKQLSLHPQVLPLPH-SSLEHDRPAN-PTSMLSSPEKRSNSPLT XP_004857133.1/1-1410 VTMLCALDENLNRTLDPSQLSLHPQMLPLLH-SSPEQDRPTN-PTSMLSSPEDRDNSPLT :*::*.*********:*.*:**:**:*** * ** * :* :: *..:****:.:... * ENSMUSP00000137933/1-1429 PFKTAAPFVSCSTQGASFSLDYLLPHSVVHLEGCTEQSSATDNELSPEQASWEDSRGHFL ENSRNOP00000019410/1-1430 PFKTPARLVGCSTQGASVSLDCSHRHSVLHLEGCTEQSSTTDSRLSSEHMNWEDSQGDFL ENSP00000444743/1-1450 ALETAAPFVSHTTHLLSASLDYLHPQTMVHLEGFTEQSSTTD-EPSAEQVSWEESQESPL ENSCPOP00000005164/1-1417 APETTAPFISHTTHI-PANLDYMHPQTVVHLEGCTKQSSTTDSEPSTEQVNWAETQKGHL XP_004857133.1/1-1410 ALETTAPFISHTTHILPANFDYLHPQTIVHLEGCTEQSSTTDSEPSAEQVSWEESQKGHL . :*.* ::. :*: . .:* ::::**** *:***:** . *.*: .* ::: * ENSMUSP00000137933/1-1429 SSGSGMAHTSSPLTNEDLSLINKLGDSVGVLQKKLDPSPEACRIPHSSSSENIRDLSHSR ENSRNOP00000019410/1-1430 SSSTGMAHTSSPLTNEDLSLINKLGDSVGVLPKKLDPSPEACRIPHSSSSENIRDLSHGP ENSP00000444743/1-1450 SSGSEVPYKDSQLSSADLSLISKLGDNTGELQEKMDPLPVACRLPHSSSSENIKSLSHSP ENSCPOP00000005164/1-1417 SGGDEVPHRVSQLNSKDLRVISKFGGNIGELKKKLDPLQASWQLPHSSSSENIKGLHHSP XP_004857133.1/1-1410 SGGDEAPHKGSQLNCKDLNLISKLDDNIGELQKKLDPSQVAWRLPHSSSSENIKGLSHSP *.. .: * *. ** :*.*:... * * :*:** : ::*********:.* *. ENSMUSP00000137933/1-1429 GVVKEHAKEIESRVIFQAGFSKTSQMKRSASLAKLGYLDLCKDYLPDRELVSSESPHLKL ENSRNOP00000019410/1-1430 GVVKEHAKEIEPRVIFQAAFSKTSQMRRSASLAKLGYLDLCKDYLPDRELGSSESPHLKL ENSP00000444743/1-1450 GVVKERAKEIESRVVFQAGLTKPSQMRRSASLAKLGYLDLCKDCLPEREPASCESPHLKL ENSCPOP00000005164/1-1417 RKVKECAK-VESQVIFQAGVTKPSQMRRSASLAKLGYLDLCKDCLPERQAVSSEYPHLKL XP_004857133.1/1-1410 GVVKERAKEIESRVIFQVRIPKPSQMRRSASLAKLGYLDLCKDCLPERESVSSESPHLKV *** ** :*.:*:**. ..*.***:**************** **:*: *.* ****: ENSMUSP00000137933/1-1429 LQPFLRTDSGMHALMAHEPSESAGAQQNPQPTKYSVEQLKTSECIVQSKPVERPSVQYAK ENSRNOP00000019410/1-1430 LQPFLRTDSGMHALMVHEPSESPGAHPNPQPTKYFVEQLKTTECVVQSKPVERPHVQYAK ENSP00000444743/1-1450 LQPFLRTDSGMHAMEDQESLENPGAPHNPEPTKSFVEQLTTTECIVQSKPVERPLVQYAK ENSCPOP00000005164/1-1417 LQPFIRTDSGMHAMEAQEPPENPGASQNPEPTKYFVEQLRTTECIAQSKPVERPLAQYAK XP_004857133.1/1-1410 LQPFIRTDSGMHAMEAQAPPENLDATQNTEPTKYFVEPLKTTECIAQSKPVERPLVQYAK ****:********: : . *. .* *.:*** ** * *:**:.******** .**** ENSMUSP00000137933/1-1429 EFGYSQQCLLPKARPELTSSEGGLPLLQTQGLQYTGPSPGLAVAPRQQHGRTHPLRRLKR ENSRNOP00000019410/1-1430 EFGFSQQCLLPKARPELTSSEGGLPLLQTQGLQYPGPSPGLAVAPRQQHGRTHPLRRLKR ENSP00000444743/1-1450 EFGSSQQYLLPRAGLELTSSEGGLPVLQTQGLQCACPAPGLAVAPRQQHGRTHPLRRLKK ENSCPOP00000005164/1-1417 EFGCSQQCLLPRAGRELTSSEGGLPLLQTQGLQEAGSAPGLAVAPRQQHGRTHPLRRLKR XP_004857133.1/1-1410 EFGYSQQCLLPRVRRELTSSEGGLPLLQTQGLQDAGPAPGLAMAPRQQHGRTHPLRRL-R *** *** ***:. **********:******* . .:****:*************** : ENSMUSP00000137933/1-1429 ANDKKRTTNPFYNTM ENSRNOP00000019410/1-1430 ANDKKRTTNPFYNTM ENSP00000444743/1-1450 ANDKKRTTNPFYNTM ENSCPOP00000005164/1-1417 ANDKKRTTNPFYNTM XP_004857133.1/1-1410 TNDKKRTTNPFYNTM :**************