CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000027103/1-689 ----------------MNSKARSLLWTIRRFSTLLPRSRALRIDPLGTCRPEVIHSKWNP ENSRNOP00000017281/1-679 ----------------MNNRAHTFLWGIRQFRTSIPRSRALRTYSLVFCKPEVIHSKRNP ENSP00000236980/1-710 MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWN- ENSCPOP00000005070/1-713 HSDIWKAFERVSLDSKMSNKTGSILWSLRRFSTLVPARRTLSIYSLGLCRPKLAHSNWNP XP_004851211.1/1-741 ----------------MSNKARSNIWNLRQFSTLVLASRTSSIYPLGFCRSKIDHSNWNL *..:: : :* :*:* * : *: * *:.:: **: * ENSMUSP00000027103/1-689 RNHRLNVFDEGLQPS--VRYLFQDIFISKSVDGCIQTKGISHSAVFKPDRLLCPRRLSFD ENSRNOP00000017281/1-679 RNHLLNGFDEGLQPS--VRYLFQDIFISKSVAGCTQTRGIIHAAGFKLDRILCPRRLSFD ENSP00000236980/1-710 ---ILNNFHNRMQSTDIIRYLFQDAFIFKS-DVGFQTKGISTLTALRIERLLYAKRLFFD ENSCPOP00000005070/1-713 RNCPINDFDNRMQPS-VVRYLFWDALMLKSQNDGFESENLNTVTVFRVDR-LCSRKISFD XP_004851211.1/1-741 RNLPLNDFDNRMRPS--IRYLFQDAFILKSRNDGFQSESLNTLTVFRVNRLLCPRRISFD :* *.: ::.: :**** * :: ** ::..: : :: :* * .::: ** ENSMUSP00000027103/1-689 AKHSFVSDGTSDHDLKKINFHH-TSSEDVFTKKVRPTPVNYKKLAQECNSLSDVLDTFSK ENSRNOP00000017281/1-679 AKHSFVSDGTSDHDLMKTNFHH-TSTEDVLTKKMRPTPVNYKKLAQECNSLSDVLDTFSK ENSP00000236980/1-710 SKQSLVPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSK ENSCPOP00000005070/1-713 SKHSFISAGTCDNELKKVNFHHDVSSKDELSQEMKPTPISYTKLSEESNSLSDVLDAFSE XP_004851211.1/1-741 SKDYFVSIGISDNGLKKVDFHHEVSSEDVLSKEMKSTPINYRKLSEESNSLSDVLDTFSK :*. ::. . .*. * * :::* .*.:* :::: :.. :. **::*.********:**: ENSMUSP00000027103/1-689 APTFPGSNYFLAMWIIAKRISEDKRRFERQLMFSHPAFNQLCEQMMREAKIMHYDHLLFS ENSRNOP00000017281/1-679 APTFPGSNYFLAMWIIAKRISEDKRRFEKQLMFSHPAFNQLCEQMMREAKIMRYDHLLFS ENSP00000236980/1-710 APTFPSSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFS ENSCPOP00000005070/1-713 APTFPSSKYFLALWTVAKRMSEDQKRYEKQLMFKHPAFNQLCEQAIREANRMHYNQLLYS XP_004851211.1/1-741 APTFPSSKYFLAMWTVAKRMSDDQKRCEKQLMFNHPAFNQLCKEMMKEAKIMRYDHLLFS *****.*:** *:* :***:*:*::* *::***.********:. ::**: *:*. **:* ENSMUSP00000027103/1-689 LNAIVKLGIPQNTLMVQTLLRTIQERINECDERCLSILSTALVSMEPCMNVNALRAGLRI ENSRNOP00000017281/1-679 LNAIVKLGVPQNSLMVQTLLRTIQERISECDERCLSILSTALVTMEPCMNVNALRAGLRI ENSP00000236980/1-710 LHAIVKLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRI ENSCPOP00000005070/1-713 LHAIVKLGVFQNTLVVQTLLRVIQERINECDERDLSILSALLQAMEPCKNVHALQTGLWL XP_004851211.1/1-741 LHAIVKLGVFQNSLLVQTLLRVIQERITECDERCLSILSTLLEALEPCQNVQALRTGLWL *:******: **:::******. ****.**** **:**: * ::*** **:.*::*: : ENSMUSP00000027103/1-689 LVDQQVWNIKHVFTLQTVMKCIGKDAPSALKKKLEMKALKELGRFSILNSQHMFEVLAAM ENSRNOP00000017281/1-679 LVDQQVWNINDIFTLQTVMRCIGKD----------MKALKELGRFSVLNSRHMFEVLAAM ENSP00000236980/1-710 LVDQQVWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAM ENSCPOP00000005070/1-713 LVDQQVWKIKHIFSLQTVMKYIGKDAPVALKRKLEIKALMELSRFSHVNSLHMFEVLASM XP_004851211.1/1-741 LVDQQIWKIKHVITLQTIMRYIGKDAPVALKRKLEMKALRELGGFSALNSQHMFKSLSAM *****:*:*:.:::**.:*: **** :*** **. ** :** ***: *::* ENSMUSP00000027103/1-689 DLRSVVLLNECSKVVIDNVHGCPFKVLISILQSCRDLRYQNEDLFKSIAEYVATTFDIWK ENSRNOP00000017281/1-679 DHRSVVLLNECSKIVIDNIHGCPFKVLISILQSCRDLRYQNEDLFKSIADYVATTFDIWK ENSP00000236980/1-710 NHRSLILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWK ENSCPOP00000005070/1-713 NHRSVVLLNACSKVAVDNIHGCSIKIFISILQSCKDLRYYNSDLFKGIADYVATTFDIWK XP_004851211.1/1-741 NHRSVVLLNECSKMVLDNIHGCPLKVCMDILESCIDLRYHNSDLFKGIADYVAVTFDIWK : **::**: ***:.:**:***.::: :.**:** **:* * ****.:*:***.****** ENSMUSP00000027103/1-689 LKQVIFFLLLFETLGFRPPGLMDKLMEKVVQEPGSLNVKNIVSILHVYSSLNHVHK--IH ENSRNOP00000017281/1-679 LKHVIFFLLSFETLGFRPPGLMDKLLEKVVQEPGSLTVKNIVSVLHVYSSLNHVHN--VQ ENSP00000236980/1-710 FRKVLFILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYK--CQ ENSCPOP00000005070/1-713 VKHVVFLLILFEKLSFRPLYLMNVFVKKITEEPELLNQKNIISILHVYSSLNYIDKELCS XP_004851211.1/1-741 LQKVFFLLLMFEKLGFRPIELMDLFMKKIVEEPKSLTKKNIVPILHVYSSLNHINK--CQ .::*.*:*: **.*.*** **: :::::.::* *. ***:.:**.*****:: : ENSMUSP00000027103/1-689 N-REFLEALASALTGCLHHISSESLLNAVHSFCMMNYFPLAPINQLIKENIINELLTSGD ENSRNOP00000017281/1-679 N-REFLEALASALTGCLHQISSESLLNAVHSFCMMNYFPLAPINQLIKENIIHELLTSGD ENSP00000236980/1-710 NKEQFVEVMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDD ENSCPOP00000005070/1-713 NVEKFLDMIARTLTDCLHHVSHENLLDALCSFCKMNYFPSTLLDELLQKDVISELLTTGD XP_004851211.1/1-741 N-KEFLEVMAGALTDYLYHISSENLLNATCSFCMMNYFPLAFVDQLLQKDVISELLTSDD * .:*:: :* :**. *: :* *.**:* *** ***** : .::*:::::* ****:.* ENSMUSP00000027103/1-689 TEKNIHKLHVLNTCLKLDESTY-KSVHIPLPQLP--LSASQPNEKLAEVLSRLLEGE-GR ENSRNOP00000017281/1-679 TEKNIHKLHVLNTCLKLDESTY-KCIHIPLPQLP--LTASHPNEKLAEVLSRLLEGD-GC ENSP00000236980/1-710 M-KNAYKLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGE-GH ENSCPOP00000005070/1-713 TEKNIYKLHVVDACLQLDCASYPKAIGTALPLLP--SFPSFPNEKVTEGLNRLLEGSRDF XP_004851211.1/1-741 MEKNVHKLHILDACLKLDLSSYHKGIDTALPQLP--LSPSYPNAKVVKVLSRLLGDSKGF ** :*** :::**:** : * : : .** ** .* .* *:.: *. ** .. . ENSMUSP00000027103/1-689 FSRNVPLPHNYHI-DFEIRMDTNRTQVFSFSDVDASSATNMQRVAVLCVPKSVYCLNSCH ENSRNOP00000017281/1-679 FSRNVQLPHNYHI-DFEIRMDTNRTQVFSFSEGDASSATNMQRVAVLCVPKSAYCLNSNH ENSP00000236980/1-710 FSKDVHLPHNYHI-DFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSH ENSCPOP00000005070/1-713 LSKDVQLPHNYYIADFEIRTDANRRQVLGLSDV--SWFIFVFRVAVLCVPKSAYCLDLSH XP_004851211.1/1-741 FSKDVQLPHNYHI-DFEIRMDANRKQVLSFSDADVPSATNMQRVAVLCVPRSGYCLHSSH :*::* *****:* ***** *:** **: :*: . : *******.:* *** * ENSMUSP00000027103/1-689 PRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEVLPTADTTV---- ENSRNOP00000017281/1-679 LRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEALATTDESV---- ENSP00000236980/1-710 PRGFLAMKMRHLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ ENSCPOP00000005070/1-713 PRGFLAMKIRHLNIMGFHVVLVKRWEMEKLKMEDAILFLKNKIYSSEVVPTKANSQSPY- XP_004851211.1/1-741 PRGFLATKIRHLNTMGFHVVLVKSWEMKKLTMKDAVKVLKTKIYSXEVLPTTDVNLQNSF **::* *:**** *****:*:: **:.** *:**: .::.**** *.:.. . ENSMUSP00000027103/1-689 --------------------------------------------- ENSRNOP00000017281/1-679 --------------------------------------------- ENSP00000236980/1-710 --------------------------------------------- ENSCPOP00000005070/1-713 --------------------------------------------- XP_004851211.1/1-741 SSKNQPFHIRMHRFVKITLIKTVVRLSMELTWLLTESENVILVHC