CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 ----------MSIPVAPKKSCFSQLQDNRNGSKNNNESILSLGDTNANQIMLEVSSSQDE ENSP00000392057/1-1379 MASSPTKGLTMSVPVAPKKSCYTQLRDNRNAARNNNESILSLGDTNANQIMLEVSSSHDE ENSMUSP00000082694/1-1353 ----------MSVPLAPKKSCFGQLRDHREGAKNNNESILRTGDTNANQIMLEVSSSCDE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 SKTCDLTDQIGNANSSGLEHHVHFHKEPHQLQGFRRGSQSASTSLKDLKLSPTFPRGLQE ENSP00000392057/1-1379 SKTCDLGDEIGNTNSSEPENRTHFHKEFHQLQGFGKGSQAGSASLKDFRLSSTIQRELNE ENSMUSP00000082694/1-1353 AKSRDLDDELGNSNLSRPQYHSHFQKEPLHLQGFGKGSQAGSTSQRESQASLTVHRQLSE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 DCTMERGTDISQTPWSAQGPTLSSWMNMTGEASSEVLAKKDVEVPRHVPKDKLAKTLDNE ENSP00000392057/1-1379 EHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPKDKLAKTLDNE ENSMUSP00000082694/1-1353 EHAVKRGA--LQAPQCVQGPSLSSWRNAVGQASPEASAKKDAEIPRHIPKDKLAKTLDNE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 ELRRHSLESASSSAAVAGSLPPQHLQLARPNALEPWGPVPRDGEELQRTLADYSLGTAFP ENSP00000392057/1-1379 ELRRHSLERASSSVAAVGSLTPQHPQPLSLDSREARGQIPGGGEGPQKTLPDHAVPAAFP ENSMUSP00000082694/1-1353 ELKR-----ASSCSAAAGSVPPTDLQPVQLDTLGPQDHVPARGEGPQRTPASHSPGKGFS ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 SADNTSERKSVHPPKPSTSEARKTTPSEAQMEGAHTLNVCNEHKSHPAHSEPALNSTLVS ENSP00000392057/1-1379 ATDSTSEGKSVRHPKPSTSESKQSTPSETQTVGAHVLQVCSEHTSHSAHPEPALNLTLAS ENSMUSP00000082694/1-1353 PGEGTSEGNSVYLPKPSTSEAKGSSPSDTKMEGPHGLDVYNERITH-AELTPSSASASKE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------------------------------------------------ XP_004854850.1/1-1366 KEILSYTEAQLGQRKGEPKLELKYVQLRA-GQELKSNLADDLGCHKEERMSPLERKEPCG ENSP00000392057/1-1379 KEIPSKLEAQLGQGKGEAKLDLKYVPPRRVEQEGKAAQEGYLGCHKEENLSALEGRDPCG ENSMUSP00000082694/1-1353 NPGLRHPEVCLGQGTGKSKVELKSVQPRN-EEGLTSAQAQGPGCHEERSMSPVERQELLE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ------------------QHLRVGR--CSSEGSGAGTGMEEPLQTTLAQVPASLGVPGTQ XP_004854850.1/1-1366 EAQQEATSAISGPSDSICHHFGVGRGGS--EDTGVNKGVEESLQTTLKQVTASLEVAGNQ ENSP00000392057/1-1379 EAHPEATDALGHLLNSDLHHLGVGRGNC-EEKRGVNPGEQDSLHTTPKQGSASLGGADNQ ENSMUSP00000082694/1-1353 KAYREATSQ----GNSSHRQLGVRRGSSLEEMTGVSAGVEGSQQATPTLSAAPAGEAGTR ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 LTGRASLSTGSRLGEMTAGSFFPEGGQVATVPNGLPDSTPSQVSEETRRLDTGNRDRAVG XP_004854850.1/1-1366 LTCKMSQSTGSKLDEMTSSDFLPGNGHVAIVPNGLPESKPSDVSEERRTLDIGNREGAVV ENSP00000392057/1-1379 PTGKISPCAGEKLGERTSSSFSPGDSHVAFIPNNLTDSKPLDVIEEERRLGSGNKDSVMV ENSMUSP00000082694/1-1353 LTGKMSAGVGRMARETASGQTAPDVGQAAPVRRDPTESVPSEVSGEERRLGSGNSGSTKL ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 LAADPAVREHKAEVPESLCLQTKSSEVGESKHVATLMAEPKNLLENAAKTVVAPSKEDSF XP_004854850.1/1-1366 FVSDPSVRDRKTEVPESLDLQSRSSEVGESKDTTTPVTEPRNLRENAAKTDITPSRADSF ENSP00000392057/1-1379 LVFNPSVGENKTEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSV ENSMUSP00000082694/1-1353 LASGPSAGGSRTDTSGLLSPRGSNLEARKGKEM---VAENRNLLENAAQTDNTPAGVDSA ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 LSTPAT-LHPETTVNVTHQPAPPSSIFQDLDVFSVGTGSPSVVPPSTDSVQQVNASSEVP XP_004854850.1/1-1366 LNTPAT-LHPEITVNMTHQPTPPSSIFQEPGVFIVDTGSPSLVPPSTDSMQLLNTSPEVP ENSP00000392057/1-1379 LNIPAP-LHPETTVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVP ENSMUSP00000082694/1-1353 FSTPAPLLHPETTVNSSHHPTPPGSSSQELGVFSGDTGSPSVASPPTDGGQVLNTSPKVP ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 DKNTCPSGIPKPVVTHSKGATSLQEGTEKLLVEKVEDRTDTKPILMPKPKHVRPKIITYI XP_004854850.1/1-1366 DKNIFPSGIPKPFVTHSKGTTSLQEGMEKHQVEKMEDRTDTKPIIMPKPKHVRPKIITYI ENSP00000392057/1-1379 DKNTCPSGIPKPVFTHSKDTPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYI ENSMUSP00000082694/1-1353 DRTTCSSGIPKPP-THPKDTPSSQEAREKLETEKMEERAEAKPILMPKPKHVRPKIITYI ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 RRNPQALGPVDTSLVSVGLPYAP-------AQEDRAASDDLKSPASLYEKFKPDLQKPRV XP_004854850.1/1-1366 RRNPQALGPVDTSLVSVGLPYAPPTCSMPLPQEDRVASGDLKSSANIYEKFKPDLQKPRV ENSP00000392057/1-1379 RRNPQALGQVDASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRV ENSMUSP00000082694/1-1353 RRNPQALSQGDASLVPVGLPYAPPTCGMPLPQEEKAASRDLQPSANMYEKLKPDLQKPRV ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 FSSGLMVSGIKPPGHPFSPVSEKFLQEVADHSGKEEFCSPPCTHYEVPPTFYRSAMLLKP XP_004854850.1/1-1366 FSSGLMVSGIKPPGHPFSQMSEKFLQEVTDHSGKEEFCSPPYTHYEVPPTFYRSAMLLKP ENSP00000392057/1-1379 FSSGLMVSGIKPPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPTFYRSAMLLKP ENSMUSP00000082694/1-1353 FPSGLMVSGIKPPAHHFSQMSEKFLQEVADHPGKEEFCSPPYTHYEVPPTFYRSAMLLKP ENSRNOP00000060535/1-315 ------------MGHH---------------------CCKPY------------------ .* *. * ENSCPOP00000005028/1-993 QLGLGAVSRLPSAKSRILIASQRASASAIHPPGPITATASLYAPEPSADLKKASSSNATK XP_004854850.1/1-1366 QLGLGAMSRLPSAKSRILIASQRSSASTIHPPAPITTATSLYASDPS-DLKKASSSNAAK ENSP00000392057/1-1379 QLGLGAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAK ENSMUSP00000082694/1-1353 QLGLGAMSRLPSTKSRILIASQRSSASAIHPPGSLTTAASFYGSDPS-DLKKASNSNAAK ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 SNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSVDNAQPEESRPVTRSTFGSE XP_004854850.1/1-1366 SNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSVDSAQPEQNRPVTRSTFGSE ENSP00000392057/1-1379 SNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNE ENSMUSP00000082694/1-1353 ASLPKSGLRPPGYSRLPAAKLAAFGFVRSSSISAVPSSQSLDSVQPEQSRPVTRSTFGNE ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 EQPALKTAVPFKDTSKGAGRVASPASSSVTTPRRSLLPAPKSTSTPAGIKKEAQKDQDAN XP_004854850.1/1-1366 EQIAQKAAVPFKDTPKGPSRVASAASSSVTTPRRSLLPAPKSTSTPAGIKKEAQKDQDAS ENSP00000392057/1-1379 EQPVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTN ENSMUSP00000082694/1-1353 EQAPLKQALPSKDTPKGAGRAAPASSSNATTPRRSLLPAPKSTSTPAGAKKELQKDPEAK ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 KPAVSSPKRIAASTTKLHSPGYPKQRTAAPRNGFVPKPDPQAREAERQLVQRLKERCERQ XP_004854850.1/1-1366 KPTVSSPKRIATSTSKLHSPGYPKQRTAAPRNGFVPKPDPQAREAERQLVQRLKDRCERQ ENSP00000392057/1-1379 KPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQ ENSMUSP00000082694/1-1353 KPAVSSPKRTASAATKPHSPGYPKQRTSAPRNEFPPKPDLQAREAERQLAQRLRDRCEWQ ENSRNOP00000060535/1-315 ------------------------------------------------------------ ENSCPOP00000005028/1-993 ARQLSLTQGQLRRAICGFDAVAVSMQYFFGKNESALVKEKELSIELANIRDEVAFNTAKC XP_004854850.1/1-1366 ARHLSLIQGELRRAICGFDAVAVSMQYFFGKNESALVKEKELSIELANIRDEVAFNTAKC ENSP00000392057/1-1379 TRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKC ENSMUSP00000082694/1-1353 ARQLGLARRELKKAIQGFDALAVSTKHFFGKSERALAKEKELSIELANIRDEVAFNTAKC ENSRNOP00000060535/1-315 ----------------------ICLQCLDKTSERALAKEKELSIELANIRDEVAFNTAKC :. : : ..* **.******************:**** ENSCPOP00000005028/1-993 EKLQKEKEDLERRFEEELRRMGWQQQAELQELQERLQLQFEAEMARLQEEHHGQLLQIRC XP_004854850.1/1-1366 EKLQKEKEDLERRFEEELRRMGWQQQAELQELQERLQLQFEAEMARLQEEHHGQLLRIRC ENSP00000392057/1-1379 EKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRC ENSMUSP00000082694/1-1353 EKLQKEKETLERRFEEELRRLGWQQQAEVQELQERLQQQFQAESARLQAEHQDQLLRMRC ENSRNOP00000060535/1-315 EKLQKEKEALERRFEEELRRLGWQQQAEVQELQERLQQQFQAESARLQAEHQDQMLRMRC ******** ******:*::*:*******:***:**** **:** **** ** .*:* :** ENSCPOP00000005028/1-993 QHQEQVEDITASHEAALLEMENNHTVAIAILQDDHDHKVQELVSTHELEKKELEENFEKL XP_004854850.1/1-1366 QHQEQVEDITTSHEAAFLEMENNHTVAIAILQDDHDHKVQELVSAHELEKKELEENFEKL ENSP00000392057/1-1379 QHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKL ENSMUSP00000082694/1-1353 QHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELMSTHEFEKKELEENFEKL ENSRNOP00000060535/1-315 QHQEQVEDITASHEAALLEMENNHTVAITILQDDHDHKVQELMSTHEFEKKELEENFEKL ********:*:**:**:***********:*************:*:**:************ ENSCPOP00000005028/1-993 RLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEVALAPYQHLEEDMKSLKQVLEM XP_004854850.1/1-1366 RLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEVALAPYQHLEEDMKSLKQVLEM ENSP00000392057/1-1379 RLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEM ENSMUSP00000082694/1-1353 RLTLQDQVDTLTFQSQSLRDRARRFEEALRKTTEEQLEIALAPYQHLEEDMQSLKQVLEM ENSRNOP00000060535/1-315 RLSLQ---------------------------------IALAPYQHLEEDMQSLKQVLEM **:** :************:******** ENSCPOP00000005028/1-993 KNQQIHQQEKKIMELEKLAEKNVILEEKIQVLQQQNEDLKVRIDQNTVVTRQLSEENANL XP_004854850.1/1-1366 KNQQIHQQEKKIIELEKLAEKNIILEERIQVLQQQNEDLKARIDQNTVVTRQLSEENANL ENSP00000392057/1-1379 KNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANL ENSMUSP00000082694/1-1353 KNQQIHLQEKKIIELEKLVEKNIILEERIQVLQQQNEDLKARIDQNTVVTRQLSEENANL ENSRNOP00000060535/1-315 KNQQIHLQEKKIIELEKLVEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANL ****** *****:*****.***:****:************.******************* ENSCPOP00000005028/1-993 QEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPIYRGSSSGPSSPARVSTTP XP_004854850.1/1-1366 QEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTMP ENSP00000392057/1-1379 QEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTP ENSMUSP00000082694/1-1353 QEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTP ENSRNOP00000060535/1-315 QEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTP *****************************************:**************** * ENSCPOP00000005028/1-993 R XP_004854850.1/1-1366 R ENSP00000392057/1-1379 R ENSMUSP00000082694/1-1353 R ENSRNOP00000060535/1-315 R *