CLUSTAL W(1.81) multiple sequence alignment ENSP00000260600/1-1144 ------MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMR ENSMUSP00000020984/1-1145 ------MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMR ENSRNOP00000005389/1-1144 ------MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMR ENSCPOP00000005012/1-1133 KQTPARMPRNQGFSD------------LSLPSDPERGVGRTHEISVRNSGSCLCLPRFMR XP_004839159.1/1-1145 ------MPRNQGFSEPEYSAEYSAEYSVSLPSDPERGVGRTHEISVRNSGSCLCLPRFMR ********: :******:************************* ENSP00000260600/1-1144 LTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLASLAVAGIG ENSMUSP00000020984/1-1145 LTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGFG ENSRNOP00000005389/1-1144 LTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGVG ENSCPOP00000005012/1-1133 LTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLIVAGVG XP_004839159.1/1-1145 LTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLVVAGIG ****************************************************.* ***.* ENSP00000260600/1-1144 LVLDIILFVLCKKGLLPDRVTRRVLPYVLWLLITAQIFSYLGLNFARAHAASDTVGWQVF ENSMUSP00000020984/1-1145 LVLDIILFVLCKKGLLPDRVSRKVVPYLLWLLISAQIFSYLGLNFSRAHAASDTVGWQAF ENSRNOP00000005389/1-1144 LVLDIILFVLCKKGLLPDRVSRKVVPYLLWLLITAQIFSYLGLNFSRAHAASDTVGWQAF ENSCPOP00000005012/1-1133 LLLDIILFVLCKKGLLPDRVSRKVVPYLLWLVITAQIFSYLGLNFAHAHAASDTVGWQVF XP_004839159.1/1-1145 LLLDVILFVLCKKGLLPDRVSRKVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQAF *:**:***************:*:*:**:***:*:***********::***********.* ENSP00000260600/1-1144 FVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYL ENSMUSP00000020984/1-1145 FVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYL ENSRNOP00000005389/1-1144 FVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYL ENSCPOP00000005012/1-1133 FVFSFFITLPLSLSPIVTISVVSCVVHTLVLGVTVAQQQQDELQGMQLLREILANVFLYL XP_004839159.1/1-1145 FVFSFFITLPLSLSPIVLISVASCVVHTLVLGVTVAQQQQEELQGMQLLREILANVFLYL ***************** ***.******************:**:**************** ENSP00000260600/1-1144 CAIAVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD ENSMUSP00000020984/1-1145 CAIIVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD ENSRNOP00000005389/1-1144 CAIIVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD ENSCPOP00000005012/1-1133 CAIVVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD XP_004839159.1/1-1145 CAIIVGVMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD *** **:***************************************************** ENSP00000260600/1-1144 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL ENSMUSP00000020984/1-1145 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL ENSRNOP00000005389/1-1144 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL ENSCPOP00000005012/1-1133 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL XP_004839159.1/1-1145 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL ************************************************************ ENSP00000260600/1-1144 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVG ENSMUSP00000020984/1-1145 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVG ENSRNOP00000005389/1-1144 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVG ENSCPOP00000005012/1-1133 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVG XP_004839159.1/1-1145 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTRTGVDMRVG ***************************************************:******** ENSP00000260600/1-1144 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGD ENSMUSP00000020984/1-1145 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGD ENSRNOP00000005389/1-1144 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGD ENSCPOP00000005012/1-1133 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGD XP_004839159.1/1-1145 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGD **********************************************:************* ENSP00000260600/1-1144 GGSRCDYLEEKGIETYLIIASKPEVKKT-ATQNGLNGSALPNGAPASSKSSSPALIETKE ENSMUSP00000020984/1-1145 GGSRCDYLDEKGIETYLIIASKPEVKKT--AQNGLNGSAVPNGAPASSKPSSPALIETKE ENSRNOP00000005389/1-1144 GGSRCDYLDEKGIETYLIIASKPEVKKT--AQNGLNGSALPNGAPA-SKPSSPALIETKE ENSCPOP00000005012/1-1133 GGSRCDYLEEKGIETYLVIASRPEVKKTAATQNGLYGSTLPNGAPMSSKPSSPIFIETKE XP_004839159.1/1-1145 GGSRCDYLEEKGIETYLVIASKPEVKNT-ATQKGRHGLALPNGAPVSSKPSSPVLIETKE ********:********:***:****:* :*:* * ::***** **.*** :***** ENSP00000260600/1-1144 PNGSAHSSGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEA ENSMUSP00000020984/1-1145 PNGSAHASGSTSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEA ENSRNOP00000005389/1-1144 PNGSAHASGSTSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEA ENSCPOP00000005012/1-1133 QNGSTHTSGSTSEEPEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEA XP_004839159.1/1-1145 PNGSAHTSGSTSEEPEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEA ***:*:******:.***:***************************************** ENSP00000260600/1-1144 LLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILI ENSMUSP00000020984/1-1145 LLERESAQVVKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILI ENSRNOP00000005389/1-1144 LLERESAQVVKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILI ENSCPOP00000005012/1-1133 LLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILI XP_004839159.1/1-1145 LLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILI ******************:*******************************:***:***** ENSP00000260600/1-1144 DPWLMTNYVTFMVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAI ENSMUSP00000020984/1-1145 DPWLMTNYVTFVVGEVLLLILTICSMAAIFPRSFPKKLVAFSSWIDRTRWARNTWAMLAI ENSRNOP00000005389/1-1144 DPWLMTNYVTFVVGEVLLLILTICSMAAIFPRAFPKKLVAFSSWIDRTRWARNTWAMLAI ENSCPOP00000005012/1-1133 DPWLMTNYVTFVAGEILLLILTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAI XP_004839159.1/1-1145 DPWLMTNYVTFVVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAI ***********:.**:******:**:******:*********:***************** ENSP00000260600/1-1144 FILVMANVVDMLSCLQYYTGPSNATAGMETEGSCLENPKYYNYVAVLSLIATIMLVQVSH ENSMUSP00000020984/1-1145 FILVMANVVDMLSCLQYYMGPYNMTAGMELDGGCMENPKYYNYVAVLSLIATIMLVQVSH ENSRNOP00000005389/1-1144 FILVMANVVDMLSCLQYYMGPYNVTTGIELDGGCMENPKYYNYVAVLSLIATIMLVQVSH ENSCPOP00000005012/1-1133 FILVMANTVDMLSCLQYYTGPHNGTAELQLEGSCLENPKYYSYIAVLALIATIMLVQVSH XP_004839159.1/1-1145 FILVMANVVDMLSCLQYYAGPYNGTAELELEGSCLENPKYYSYIAVLSLIATIMLVQVSH *******.********** ** * *: :: :*.*:******.*:***:************ ENSP00000260600/1-1144 MVKLTLMLLVAGAVATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQGF-NPGLNGTD- ENSMUSP00000020984/1-1145 MVKLTLMLLVTGAVTALNLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLATPGLNGTDS ENSRNOP00000005389/1-1144 MVKLTLMLLVTGAVTAINLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLSTPGLNGTDS ENSCPOP00000005012/1-1133 MVKLTLMLLVTGAAAALSLHTWRPVFDDYDRRRFQEHASPRVASEAVWGLPTLGLNGTD- XP_004839159.1/1-1145 MVKLTLMLLVTGAAATISLYTWCPVFDKYDHKRFQEHAFPMVASEKMQVLSTPGLNGTD- **********:**.:::.*::* ****.**::**:*: * ** * : : . ****** ENSP00000260600/1-1144 RLPLVPSKYSMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEAL ENSMUSP00000020984/1-1145 RLPLVPSKYSMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEAL ENSRNOP00000005389/1-1144 RLPLVPSKYSMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEAL ENSCPOP00000005012/1-1133 RLPLVPSKYSMTAMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEAL XP_004839159.1/1-1145 RLPLVPSKYSMTVMILIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEAL ************.*:::******************************************* ENSP00000260600/1-1144 VTNMLPEHVARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRF ENSMUSP00000020984/1-1145 VTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRF ENSRNOP00000005389/1-1144 VTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRF ENSCPOP00000005012/1-1133 VTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRF XP_004839159.1/1-1145 VTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRF **************************:********************************* ENSP00000260600/1-1144 LNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQ ENSMUSP00000020984/1-1145 LNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQ ENSRNOP00000005389/1-1144 LNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQ ENSCPOP00000005012/1-1133 LNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDRERWQ XP_004839159.1/1-1145 LNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQ *********************************************:**.**:**::**** ENSP00000260600/1-1144 HLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA ENSMUSP00000020984/1-1145 HLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA ENSRNOP00000005389/1-1144 HLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA ENSCPOP00000005012/1-1133 -------FALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA XP_004839159.1/1-1145 HLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVA ***************************************************** ENSP00000260600/1-1144 SRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNG ENSMUSP00000020984/1-1145 SRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNG ENSRNOP00000005389/1-1144 SRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNG ENSCPOP00000005012/1-1133 SRMESTGVMGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPPAFPNG XP_004839159.1/1-1145 SRMESTGVMGNIQVVEETQIILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPPAFPNG ******************* ********************************: .:**** ENSP00000260600/1-1144 PSVTLPHQVVDNS ENSMUSP00000020984/1-1145 SSVTLPHQVVDNP ENSRNOP00000005389/1-1144 SSVTLPHQVVDNP ENSCPOP00000005012/1-1133 SSITLPHQVVDSS XP_004839159.1/1-1145 SSVTLPHQVVDNS .*:********..