CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000133029/1-1148 ------------------------------MKKCRWSMDRNTDRDPQKQENKKTMNDLAQ ENSRNOP00000032210/1-1148 ------------------------------MKKHRWSMDRNTDRDPQKQLNQKTMNDVTQ ENSP00000374049/1-1184 MKKYRKISIGCFAMATQTSHVFHGQENMFLENHC---IRRNTGRDSKKPLKQKNMNGLGQ ENSCPOP00000004913/1-1144 ---------------------------------C--SMKRNTNRH-QKQLSQKDVNGLDQ XP_004855967.1/1-1150 ------------------------------MNKCKLSMKRNTDRH-QKQLNQKDMNGVGQ : ***.*. :* .:* :*.: * ENSMUSP00000133029/1-1148 TSQDGLLVTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTVEL ENSRNOP00000032210/1-1148 NSQDGLLVTHVNQTQDLLRLQRSETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTVEL ENSP00000374049/1-1184 NSDNGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGTEVL ENSCPOP00000004913/1-1144 NPDDGLPVTQVNQTQDLLRLQGNEIQ-SVLEDPEDWLSTHSLKFEKLTLADLISQGTAVL XP_004855967.1/1-1150 NPDNGLLVTHVNQMQDLLKLQGSEIQSPALEDCEDWLSTHNLKFQKLTLADLISQGTAVL ..::** **:*** ****:** * * . ** ****: *.** :************ * ENSMUSP00000133029/1-1148 EDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDS ENSRNOP00000032210/1-1148 EDQNNAVPKVHFTTQTIYHFTSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDS ENSP00000374049/1-1184 EEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDV ENSCPOP00000004913/1-1144 EENSSVMQEIHFSTQTICHFESKLSEIIKLYQQRIQWLTENSKKAFGLIRGTRVAILIDA XP_004855967.1/1-1150 EESSSVTQELHFSTQTICHFESKLSEVIELYQQRIQWLTENSKKAFGLIRGTRVAILIDA *: ... :: *:** * ** *:**: *::**:*::*************:*:**.:*** ENSMUSP00000133029/1-1148 SQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLW ENSRNOP00000032210/1-1148 SQVSSGPQTEEFQNDLTSLIDEQLSLKEKLYVLTFGGTTNFLWPDPVEVSASTLQELKLW ENSP00000374049/1-1184 SAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLW ENSCPOP00000004913/1-1144 SVASRGPRTEEFQNDFMSLVDEQLSLKEKLYVLSFGTTARPLWPDPTEVCTSNLQELKLW XP_004855967.1/1-1150 SVVGSGPGMEEFQNDFMSLVAEQLSLKEKLYVVSFGTATRHLWPDPVEVRTSSLQELKLW * . *. :***:*: .*: **** ****:*::** ***** ** :*.******* ENSMUSP00000133029/1-1148 VKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHV ENSRNOP00000032210/1-1148 VKTLQPEGSSNLLQALKKVLARKELNSLVAILRSCPDQPSEFLSDFIQQSTLGRSLFIHI ENSP00000374049/1-1184 VKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHF ENSCPOP00000004913/1-1144 VKKLQPEGGSNLLQALKKTFTLQGLNSLMIIMRSCPDQPLEILSDYIQQSTVGSGLIIHF XP_004855967.1/1-1150 VKELQPEGGSNLLQALKKVFTLQGLNSLVTIMRSCPDQPPEILSDYVQQSTVGSSFAIHL ** ***:*.********* :: : *:**: *:******* *:***::****:* .. **. ENSMUSP00000133029/1-1148 TTYKCDDHVPSAVLKNLTDALGGYYHCYSPESELYTSRDVVELQVETHKAQGLLSQVQAL ENSRNOP00000032210/1-1148 VTYKCDDHVPSAILKNLTDALGGHYHCYSPESELYTSRDVDELLAETHKAQGLFSQLQAL ENSP00000374049/1-1184 ITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLAEIQKAQSLLSHVQAL ENSCPOP00000004913/1-1144 ITYKCDDQVPSAVLKNLAEALGGCYHCYSPETELYTSRDVDELLAEIQKAQGLLNHIQAL XP_004855967.1/1-1150 VTYKCDDQVPAAVLKNLAEALGGRYHCYSPETELYTSRDVDELLGEIQKAQSLLNRVQAL **:***::*.*:****::*: * ******: * *****: ** * :***.*:.::*** ENSMUSP00000133029/1-1148 CHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLK ENSRNOP00000032210/1-1148 CHNNPCEELSCMIEEISTEIAKGPFTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLK ENSP00000374049/1-1184 QHSSPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLK ENSCPOP00000004913/1-1144 RQSSPCEELARMMKEIATEYTRESLTDLLPKPPKHDAPLTIVFPNLEKTSAEWLKINGLK XP_004855967.1/1-1150 RQSSPCEELARMMQEAATGYTKGSLTALLPKAPKHDAPLIVEFPNLEKTSAEWLKINGLK :..*** *: ::* : :. .: ****.***:*** : **:*:********:**** ENSMUSP00000133029/1-1148 -AKKLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLF ENSRNOP00000032210/1-1148 -AKKLGLYQVLAPNAFNPVEEFVPILQKTVGATIHEKAMVQFEWHDGTVKNIHVDPPVLF ENSP00000374049/1-1184 -AKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLY ENSCPOP00000004913/1-1144 AAKKLSLYQILAPNAFSLVEEFVPILQKTVSSTIHEKTMVQFEWHDGTVKNIHVDPPFLY XP_004855967.1/1-1150 -AKKLSLYRVLAPNVFSPVEEFVPILQKKVSSTIHEKAMVQFEWHDGTVKNVHVDPPFLS ****.**::****.*. **********.*.:*****:*:***********:*****.* ENSMUSP00000133029/1-1148 EYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLL ENSRNOP00000032210/1-1148 EYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMFIIHIQHSLRLL ENSP00000374049/1-1184 KYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLL ENSCPOP00000004913/1-1144 EYQKQLSRAMRGYERRVEWLSLASRRIWGTICEKRVVILLDISVTNSMYIIHIQHSLRLL XP_004855967.1/1-1150 EYQKQLSRAMQMYERRVEWLSLASRRIWGTICEKRVVVLLDISVTNSMFIIHIQHSLRLL :**:**.:*:: **:*::****:***:***:*::***:***:*.****:*********** ENSMUSP00000133029/1-1148 LEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKA ENSRNOP00000032210/1-1148 LEEQLSNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKA ENSP00000374049/1-1184 LEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKA ENSCPOP00000004913/1-1144 LEEQLSNKDCFNLIAFGSTVESWRPEMVPVSHDNLQRAWRWALSLQCGGSRNVLGALRKA XP_004855967.1/1-1150 LEEQLSNKDLFNLVAFGSTIESWRPEMVPVSHDSLQRAWRWALGLQCQGSRNVLGALRKA ********* **::*****:********.***:.** ******.*:* ******.***** ENSMUSP00000133029/1-1148 IEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDT ENSRNOP00000032210/1-1148 IEVDFKDKTKHESQGIYLFTGGVPDQDVHILSAYVAEACGGCDLQLNVCLFYVGEPQMNT ENSP00000374049/1-1184 VEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDT ENSCPOP00000004913/1-1144 VEVDFRDKDKHQSQGIYLLTGGIPDQDVPTLSAYMAESCGGCDLQLNVSLFSVGEPQMDS XP_004855967.1/1-1150 VEVDFRDKDRHRSQGIYLLTGGIPDQDVPTLSAYMAESCGGCDLQLNVCLFSVGEPRMDS :****:** :*.******:***:****: ****:**: *********.** ****:*:: ENSMUSP00000133029/1-1148 TPPACYASRTDTATAYKEITQAARGRFHWFGETGIYESDDINAIVSEIEKALNYSQKCAF ENSRNOP00000032210/1-1148 TPPACYASRTDTAAAYKEVTQAACGRFHWFGETGIYESDDSNAIVSEIEKALNYSQKCAF ENSP00000374049/1-1184 TPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAF ENSCPOP00000004913/1-1144 TPPACYASRSDTASAYRAIAWATGGRFHWFGDTGIYESDDINAIKSEMEKALNYSQKCAL XP_004855967.1/1-1150 MPPACYASHSDTASAYREVTRATGGRFHWFGDTGIYESDDIKAITSEMEKALDYSQKCAL *** ***::***:**: :: *: *******:******** ::* **:****:******: ENSMUSP00000133029/1-1148 LVASLKNHSEKELQSGALEKDKPRTLKQ-SQPKKHYPPKPTAPSVARMSIKDGLDGETSS ENSRNOP00000032210/1-1148 LVASLKNHSGKELLTAALQKDKPRTLQQ-SQPKKLYPPKPTAPSVARMSIKDDVDGETSS ENSP00000374049/1-1184 LMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSP ENSCPOP00000004913/1-1144 LVASLKNHLRKELENVAVSKEKPKMLKQRSQPKESSLPKPTAPSMARMNIKDDLERERSP XP_004855967.1/1-1150 LVASLKNHLGKELESAALSKEKPQMLKQRTQPKKSSLPKPAAPSMARMNLKEDLERERSP *:****** * * . *: *:**: *: :***: *:*:.* ***.:*:. : * *. ENSMUSP00000133029/1-1148 RLKALKCHPVNAA-------AQPEKEGTVEQRMKTKPR-TRPKLFLFYTEAGNSVGSVYK ENSRNOP00000032210/1-1148 QLKALRCHPLNAA-------TQPGKEGTVEQRTKANPR-TKAKLFLFYTESGNSVGSVYK ENSP00000374049/1-1184 PLKSLKWRPLSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYK ENSCPOP00000004913/1-1144 PSKSLKCRQLSGKVK-----SQLMEEGTVEWKRKIKSRAAQTALSLFYTETGNTVGSIYK XP_004855967.1/1-1150 PSKALKCRPLRGKVGIS---VQPLKEGAAEWRRKTRAQAAETALSLFYTETGNAIGSVYK *:*: : : . * :** * : * ..: :.. * ***** ** :**:** ENSMUSP00000133029/1-1148 RYTQGKSIRRINSSIQLPRKDTVCSSQEWTATCRLKRLKLELSKCLGPNCRYQKSVRGPA ENSRNOP00000032210/1-1148 RYSQGKPIRRINSSIELPRKDTLCSSQEWTATCGLKRLKLELSKCLGPNCRYQKSVRGSA ENSP00000374049/1-1184 KYPQGRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSGQRSA ENSCPOP00000004913/1-1144 KYPQRIRIRRTISSVNLPRKDTVCSSQEWLANYGLKKLKMEISRCLGPSCSHQKSTQSS- XP_004855967.1/1-1150 KYPQ-RTIRRTRSSVELPRKDTVCSSQEWVANYGLKRLRLEISRCLGPNCTHPKSAQSS- :*.* :** **::******:****** *. **:*::*:*:*:**.* : ** : . ENSMUSP00000133029/1-1148 LAEHCTLFPSIEINGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTIL ENSRNOP00000032210/1-1148 LARHCSLFPSIEINGVVRHIQWTLREMETYITGLEKVMRCYVQRLHWLLSGSRRLFGTIL ENSP00000374049/1-1184 SAKHCSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVL ENSCPOP00000004913/1-1144 -AKHCDVIPSIEINGVVRHIQWTLREMDVYIACLEKVMRCYIQRLRWLLSGSRRLFGAIL XP_004855967.1/1-1150 -ARHCDVFPSTEIKGVVRHIQWTLGEMDAYIVCLEKVMRCYTQRLQWLLSGSRRLFGAVL *.** ::** **:********* **:.** :*** * * ***:***********::* ENSMUSP00000133029/1-1148 ERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVEST ENSRNOP00000032210/1-1148 ESNVCILLDTSGSMGPHLQWMKTELVLLIWEQLRKHCDRFNLLSFARDPQPWQNTLVEST ENSP00000374049/1-1184 ESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETT ENSCPOP00000004913/1-1144 ESKVCILLDTSGSTGPYLQGVKSEMVLLIWEQLRKHCDSFNLLSFSDSLQPWQDTLVETT XP_004855967.1/1-1150 ESKVCILLDTSGSVGPYLQQVKTEMILLIWEQLRKRCDSFNVLSFSEGLQPWQDTLVETT * :********** **:** :*:*::********* * **:***: . * **:****:* ENSMUSP00000133029/1-1148 EAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSF ENSRNOP00000032210/1-1148 DAACHEAMQWVAHLQAQGSTSVLTALMKAFSFQDVQGLYLLTDGKPDTSCSLILDTVQRF ENSP00000374049/1-1184 DAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKL ENSCPOP00000004913/1-1144 DAACREAIQWLTHLQAQGSTSILQALSKAFSFHDVQGLYLLTDGKPDTSCSLVLDAVHRL XP_004855967.1/1-1150 DAACREATQWVTHLQAQGSTSILQALSKAFSFHDVQGLYLLTDGKPDTSCSLVLDAVQRL :***::* **::*********:* ** *****:*::****************:*: *: : ENSMUSP00000133029/1-1148 QKERGVKVHTISLTSADRTATEFLRELASLSGGRYHCPVSDKALSGIQGLLTRGFIKERD ENSRNOP00000032210/1-1148 QKERGVKVHTISLTSTDRAAIEFLRKLASLSGGRYHCPVSDEALSRIQGLLARGFIEERD ENSP00000374049/1-1184 REKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKD ENSCPOP00000004913/1-1144 QEERDVKVHTVSLSCTDRAAVEFLKKLASLTGGRYHCPVSGDTLCRMHSLLTRGCIDERD XP_004855967.1/1-1150 EEDRDVKVHTVSLSCTDRAAVEFLKKLASLTGGRYHCPVGEDMHCRIQGLLTRGFVHEKD .:.*.*****:**..:**:* ***::***::********. . . ::.**::* :.*:* ENSMUSP00000133029/1-1148 PKLPLFEGDDLRLLAEEFTRARNLLKQAQVFRSQLLKKNNMKSKVTSC ENSRNOP00000032210/1-1148 PKLPLFEGDDLKILTQEFTKARNLLKQAQVFRSQLLKKNGMQSKVTAC ENSP00000374049/1-1184 PTLPPFEGDDLRILAQEITKARSFLWQAQSFRSQLQKKNDAEPKVTLS ENSCPOP00000004913/1-1144 PPLPLFEGDDLRRLAQEITKTRRFLAQAQVFRSQLQKKSNDAPQVTLC XP_004855967.1/1-1150 PPLPLFEGDDLRRLSQEITKARRFLARAQVFRSQLQKKSNTEARVTPC * ** ******: *::*:*::* :* :** ***** **.. .:** .