CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000033088/1-1001 MSGLSNKRAAGDGGSGPPEKKMNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLA ENSRNOP00000025500/1-1002 MSGLSNKRAAGDGGSGPPEKKLNREEKTTTTLIEPIRLGGISSTEEMDSKVLQFKNKKLA ENSP00000325677/1-1001 MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA ENSCPOP00000004704/1-1001 MSGPGSKRAAGDGGSGPPEKKLNREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA XP_004856242.1/1-1000 MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLA *** ..***************:.************************* *********** ENSMUSP00000033088/1-1001 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQREL-S ENSRNOP00000025500/1-1002 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLQCYENQRELSS ENSP00000325677/1-1001 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGEL-S ENSCPOP00000004704/1-1001 ERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVETLLRCHERQRDL-S XP_004856242.1/1-1000 ERLEQRQACEDELRERIEKLEKRQATDDVTLLIVNRYWAQLDETVEALLRCHENQQDL-S ****************************.*****************:**:*:* * :* * ENSMUSP00000033088/1-1001 SGTEVPGCQEGLTRDVIPRPDPGTSDLREPLPVQFRAPLSEPALAFVVALGASSCEEVEL ENSRNOP00000025500/1-1002 SGTEVPGCQEGLTRDVIPRTDPGTSDLREPLPMQFRAPLSEPALAFVVALGASSCEEVEL ENSP00000325677/1-1001 SAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVEL ENSCPOP00000004704/1-1001 TGPEAPGTQEKPTRDVIPLMEPGTSELREVLPMQLRPPLSEPALAFVVALGASSSEEVEL XP_004856242.1/1-1000 ARMEAPGTQEGPTRDMIPLTEPGTSELREPLPVQLRPPLSEPALAFVVALGASSSEEVEL : *.** ** * * * :****:**: * :*:*.*****************.***** ENSMUSP00000033088/1-1001 QLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARVRTRELGRENRR ENSRNOP00000025500/1-1002 QLQGRMEFSKAAVSRVVEASDRLQRQVEELCQRVYSRGDSEAPGEVARARTRELGRENRR ENSP00000325677/1-1001 ELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRR ENSCPOP00000004704/1-1001 QLQGRMEFSKAAVSRLVEASDCLQRQVEELCQRVYSRGDGEPPSEVTWARTRELGRENRR XP_004856242.1/1-1000 QLQGRMEFSKAAVSQLVEASDCLQRRVEELCQRVYSRVDGEPPSEVARARTRELGRENRR :*************::***** ***:*********** *.*. .*.: .:********** ENSMUSP00000033088/1-1001 LQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKH ENSRNOP00000025500/1-1002 LQDLATQLQEKHHRISLEYSELQDKVTSTETKVLEMETTVEDLQWDIEKLRKREQKLNKH ENSP00000325677/1-1001 LQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKH ENSCPOP00000004704/1-1001 LQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKH XP_004856242.1/1-1000 LQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKH ****************************:******************************* ENSMUSP00000033088/1-1001 LAEALEQLNSGYYVSGSSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAE ENSRNOP00000025500/1-1002 LAEALEQLNSGYYVSGSSTGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAE ENSP00000325677/1-1001 LAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAE ENSCPOP00000004704/1-1001 LAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAE XP_004856242.1/1-1000 LAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAE ******************:***************************************** ENSMUSP00000033088/1-1001 LQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLAS ENSRNOP00000025500/1-1002 LQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLAS ENSP00000325677/1-1001 LQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLAT ENSCPOP00000004704/1-1001 LQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLAT XP_004856242.1/1-1000 LQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLAT ***********************************************************: ENSMUSP00000033088/1-1001 KNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPI ENSRNOP00000025500/1-1002 KNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPI ENSP00000325677/1-1001 KNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPI ENSCPOP00000004704/1-1001 KNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPI XP_004856242.1/1-1000 KNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPI ************************************************************ ENSMUSP00000033088/1-1001 NREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCIPTLSHPDDPG ENSRNOP00000025500/1-1002 NREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSSHCGPNLSHPDDSG ENSP00000325677/1-1001 NREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSG ENSCPOP00000004704/1-1001 NREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSTHSIPNLGHPEDSG XP_004856242.1/1-1000 NREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAPSVPNLGHPEDSG **********************************************: . *.*.**:*.* ENSMUSP00000033088/1-1001 LNALAPGKEDSGPGPGGTPDCKKEMALLAGATSATSSIKKEELVSSEDDAQALTPVTQGL ENSRNOP00000025500/1-1002 LNALAPGKEDSGPGPGGTPDSKKELALVAGATSVASSVKKEELVSSEDDAQALAPGTQGL ENSP00000325677/1-1001 VSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGP ENSCPOP00000004704/1-1001 LGTPAPGKEESGPGPVVIPDSRKEIALVPGATTTTSSVKKEELVPSEEDAQSLTPGTQGP XP_004856242.1/1-1000 LSASAPGKEESGPGPTVTPDSRKEIALVPGATTTTSSVKKEEVVPPEEDAQSLTPGAQGP :.: *****:.**** ** :**:* :.*:*:.::*:****:*..*:* *.::* :** ENSMUSP00000033088/1-1001 PSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKVEEAKRKESELLKGLRAEL ENSRNOP00000025500/1-1002 PSRGREPEARPKRELREREGPSLGPPPAASTLSRADREKAKAEEARRKESELLKGLRAEL ENSP00000325677/1-1001 SSRGREPEARPKRELQEREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAEL ENSCPOP00000004704/1-1001 SSRAREPETRPKRELREREGPSLGPLPVASALSRADREKAKVEEVKRKESELLKGLRGEL XP_004856242.1/1-1000 -SRGREPETKPKRELREREVPGLGPLPVASALSRADREKAKVEEVKRKESELLKGLRAEL **.****::*****:*** *.*** *.**:**********.**.:***********.** ENSMUSP00000033088/1-1001 KKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESK ENSRNOP00000025500/1-1002 KKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRDLEERDRRESK ENSP00000325677/1-1001 KKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESK ENSCPOP00000004704/1-1001 KKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESK XP_004856242.1/1-1000 KKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESK *************************************************:********** ENSMUSP00000033088/1-1001 KIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQL ENSRNOP00000025500/1-1002 KIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQL ENSP00000325677/1-1001 KIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQL ENSCPOP00000004704/1-1001 KIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQL XP_004856242.1/1-1000 KIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQL ************************************************************ ENSMUSP00000033088/1-1001 REKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQ ENSRNOP00000025500/1-1002 REKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQ ENSP00000325677/1-1001 REKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQ ENSCPOP00000004704/1-1001 REKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQ XP_004856242.1/1-1000 REKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQ ************************************************************ ENSMUSP00000033088/1-1001 GSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAARE ENSRNOP00000025500/1-1002 GSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAARE ENSP00000325677/1-1001 GSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAARE ENSCPOP00000004704/1-1001 GSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAARE XP_004856242.1/1-1000 GSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAARE ************************************************************ ENSMUSP00000033088/1-1001 KESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAV ENSRNOP00000025500/1-1002 KESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAV ENSP00000325677/1-1001 KESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAV ENSCPOP00000004704/1-1001 KESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAV XP_004856242.1/1-1000 KESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAV ************************************************************ ENSMUSP00000033088/1-1001 LTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS ENSRNOP00000025500/1-1002 LTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRVYIS ENSP00000325677/1-1001 LTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS ENSCPOP00000004704/1-1001 LTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS XP_004856242.1/1-1000 LTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS **************************************:***