CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000041821/1-960 MATVMNPQIDV--EVEECLIMKVEKDSEWVSEPILERSGSTECESFRKCFRQFCYEDVTG ENSRNOP00000020281/1-960 MATVINPQMDV--EVEECLIMKVEKDSGWASEPILERSDSTECESFRKCFRQFCYEDVTG ENSP00000331626/1-967 MAVALDSQIDAPLEVEGCLIMKVEKDPEWASEPILEGSDSS--ETFRKCFRQFCYEDVTG ENSCPOP00000004695/1-966 MAAVLDSQVSIPLEVEECVIMKVEKDPDWASEHFEEGLESTECETFRKCFRQFCYEDVTG XP_004856042.1/1-964 MAAALNSQISMPLEVEGCVMLKVEKDPEWASEPFLEGSDSTECETFRKCFRQFCYEDVTG **..::.*:. *** *:::*****. *.** : * *: *:*************** ENSMUSP00000041821/1-960 PHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQTWAQKQCPESGEEAVA ENSRNOP00000020281/1-960 PHEAFSKLWELCCRWLKPEMRSKEQILEQLVIEQFLTILPEKIQAWAQRQCPESGEEAVA ENSP00000331626/1-967 PHEAFSKLWELCCRWLKPEMRSKEQILELLVIEQFLTILPEKIQAWAQKQCPQSGEEAVA ENSCPOP00000004695/1-966 PHEAFSKLWELCCRWLKPETRSKEQMLELLVIEQFLTILPKKIQAWAQRQCPESGEEAVA XP_004856042.1/1-964 PHEAFSKLWELCCRWLKPEMRSKEQMLELLVIEQFLTILPKKIQAWAQRQCPESGEEAVA ******************* *****:** ***********:***:***:***:******* ENSMUSP00000041821/1-960 LVVHLEKETRRLRKQVSSPLPSEKQAPPRTVWEVADFEPEQLETQHRVVSLEEAGSLHSG ENSRNOP00000020281/1-960 LVVHLEKETRRLRKQVSGPQHSEKQAPPRTVWEVANYEPEQLETQHRVVSREEAGNFHSG ENSP00000331626/1-967 LVVHLEKETGRLRQQVSSPVHREKHSPLGAAWEVADFQPEQVETQPRAVSREEPGSLHSG ENSCPOP00000004695/1-966 LVVHLEKETGRLRRQVSSPVRLEKQAPLGTVWEIADFQQEQKETQSKVLSRKEAGSLHSG XP_004856042.1/1-964 LVVHLEKETGRFRQQVSSPIHSEKQAPLGTVWEVVDFQPEQVDTQPRVVSREEAGSLHSG ********* *:*:***.* **::* :.**:.::: ** :** :.:* :*.*.:*** ENSMUSP00000041821/1-960 HQEQLNQKREHRPLPKNAHSSVWVPVPSDEWNALDEEVTT-------QEPIRDVHTERSF ENSRNOP00000020281/1-960 HQEQLNQKREHRPLPKNAHSSVWAPVPSSEWTAVDEEATT-------QEPVRDIHTVRSF ENSP00000331626/1-967 HQEQLNRKRERRPLPKNARPSPWVPALADEWNTLDQEVTTTRLPAGSQEPVKDVHVARGF ENSCPOP00000004695/1-966 RQEQLNQKRDYQLLPRNAQSSPWVSTPTDEWNTIDQEVTTTHPPPRSQEPVKDVHVIRGF XP_004856042.1/1-964 HQEQLNQKREHRPLPRNARSSPWVPAPADEWNTVDQEVTTTHLPAGSQEPVKDVHVLRGF :*****:**: : **:**:.* *... :.**.::*:*.** ***::*:*. *.* ENSMUSP00000041821/1-960 SYKKSVQQVPAHRGLYHEIRKESAGSMVSLGDSVSAPNKIAQLEQKKEPWSVGLHSSNKR ENSRNOP00000020281/1-960 PYKRSVQQVPAHRDLYHEIRKESACSVVSLGDTVSAPNKIAQLEQKKEPWTVGLHSSNKR ENSP00000331626/1-967 SYRKSVHQIPAQRDLYRDFRKENVGNVVSLGSAVSTSNKITRLEQRKEPWTLGLHSSNKR ENSCPOP00000004695/1-966 SHKKTVHQIPAHRDLYQEIRKENVEHTVTLGNTMSLSNKIARLEQRKEPWTISPHSSNKR XP_004856042.1/1-964 SHKKTVHQIPVHRDLYREIRKENVGNTVSLGNTVSPSNKIARLEQRKEPWTVGLHSSNKR .::::*:*:*.:*.**:::***.. *:**.::* .***::***:****::. ****** ENSMUSP00000041821/1-960 NSVLQSNYIKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKE ENSRNOP00000020281/1-960 TSVLQSKISKEKSVHAVQIPARNAGKVWREQQQWGLEDEKIAGVHWSYEETKTFLAILKE ENSP00000331626/1-967 S-ILRSNYVKEKSVHAIQVPARSAGKTWREQQQWGLEDEKIAGVHWSYEETKTFLAILKE ENSCPOP00000004695/1-966 N-ILQSTYVKEKSVHAVRIPARNAGKAWREQQQWGVEDEKIAGVHWSYEETKTFLAILKE XP_004856042.1/1-964 N-VLRSAYVKEKSAHPVQIPARNARKIWRDQQQWGVEDEKIAGVHWSYEETKTFLAILKE . :*:* ****.*.:::***.* * **:*****:************************ ENSMUSP00000041821/1-960 SRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCA ENSRNOP00000020281/1-960 SRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCA ENSP00000331626/1-967 SRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCA ENSCPOP00000004695/1-966 SRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCA XP_004856042.1/1-964 SRFYETLQACPRNSQVYGAVAEWLRECGFLRTPEQCRTKFKSLQKSYRKVRNGHMLEPCA ************************************************************ ENSMUSP00000041821/1-960 FFEDMDALLNPAAHTSSTERPKVVISLP-LKRTAISAKEQVSLVEEEEGAEDSDGDEVGI ENSRNOP00000020281/1-960 FFEDMDALLNPEAHTSSTERPKAVISLP-LKRTAVSAKEQVSLVEEEEGAEDSDGDEVGI ENSP00000331626/1-967 FFEDMDALLNPAARAPSTDKPKEMIPVPRLKRIAISAKEHISLVEEEEAAEDSDDDEIGI ENSCPOP00000004695/1-966 FFEDMDALLNPTAHASSTDKPKEMISLPRLKRIGNSAKEQITSV-EEEAAEESDGDEMGI XP_004856042.1/1-964 FFEDMDALLNPAAHASSTDKPKEIVSLPRLKRIGISAKEQITLV-EEEAAEESDGDEMGI *********** *::.**::** ::.:* *** . ****::: * ***.**:**.**:** ENSMUSP00000041821/1-960 EFIRKSEIRAAPVLFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRKSKLYGVVAEQ ENSRNOP00000020281/1-960 EFVRKSEIRAAPILFQNLSGVHWGYEETKTFLDILQETRFYEALQACHRKSKLYGVVAEQ ENSP00000331626/1-967 EFIRKSEIHGAPVLFQNLSGVHWGYEETKTFLDILRETRFYEALQACHRKSKLYGAVAEQ ENSCPOP00000004695/1-966 EFIHKPEIHGAPVLYQNLSGVHWGYEETKTFLDILHETRFYEALQACHRKSKLYGAVAEQ XP_004856042.1/1-964 EFIHKPEVHGAPVLFQNLSGVHWGYEETKTFLDILHETRFYEALQACHRKSKLYGAVAEQ **::*.*::.**:*:********************:*******************.**** ENSMUSP00000041821/1-960 LRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRPSSLSTNTSEE ENSRNOP00000020281/1-960 LRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALVNCRTAALPTNTSEE ENSP00000331626/1-967 LRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAPSPSTPEE ENSCPOP00000004695/1-966 LRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINSRASAPSTNSP-E XP_004856042.1/1-964 LRECGFLRTPEQCRTKFKSLQKSYRKVKNGHVLESCAFYKEMDALINFHASAPSTDSSEE *********************************************:* :.:: ...:. * ENSMUSP00000041821/1-960 VPSLSRQERGHIEVEPREPTTWEPVETPQEAVLEDSGSERLSEEEMIEEPELEGPSGLLQ ENSRNOP00000020281/1-960 IPSLSRQERGHIEVEPQEPTTWEPEESSQEAVLEDSGSERMSEEEITEEPEFEGSAGLPQ ENSP00000331626/1-967 VPSPSRQERGGIEVEPQEPTGWEPEETSQEAVIEDSCSERMSEEEIVQEPEFQGPPGLLQ ENSCPOP00000004695/1-966 VLSSSGQETGPIEVETQESTGWEPEETSQEAIIEDSGNERMSEEEVIQEQEFQGPPGLLQ XP_004856042.1/1-964 VLSASRHERGPTEVEPQEPTGWEP-ENSQEAVIEDSSSERMSEEEVLQEQEFQGPPGLLQ : * * :* * ***.:*.* *** *..***::*** .**:****: :* *::*..** * ENSMUSP00000041821/1-960 SPAGFEIGTIIKEDPTQVMFKDTEPHRVLMEKPKRLVSQNTNPSKYCKREYFSGRHCENL ENSRNOP00000020281/1-960 SPTDFEIGNIIKEAPTQVIFKDTESHRALIEKPKRFVSQNTNPSKYGKRECFSGRHWENL ENSP00000331626/1-967 SPNDFEIGSSIKEDPTQIVYKDMEQHRALIEKSKRVVSQSTDPSKYRKRECISGRQWENL ENSCPOP00000004695/1-966 TPNDFEIGSSSKEDPTQVIYKNIEPHKTLIEKSKRIVSQNTDPSRYHKRECISGRQWENF XP_004856042.1/1-964 SPNDFEIGSSIKEDPTQVIYKDPEPHRALIEKSKRVVSQNTDPSRYRKRECISGRQWENL :* .****. ** ***:::*: * *:.*:**.**.***.*:**:* *** :***: **: ENSMUSP00000041821/1-960 QGVRQGKLMSQPRDTGKAVVHQRPCVGRRPYRLLKYGENFGRSARLVCRMTHQKENPFKC ENSRNOP00000020281/1-960 QGVRQGKLMSQPRDTGKAVVHQRPFVGRRPYRLLKYGENFGRSARLVCRMTHQKENPYKC ENSP00000331626/1-967 QGIRQGKPMSQPRDLGKAVVHQRPFVGKRPYRLLKYGESFGRSTRLMCRMTHHKENPYKC ENSCPOP00000004695/1-966 QGIRQGKLMLQPRDLGKAVMHQRPLMGRRPYRLLKYGESFGRSARLMCRMTHQKENPYKC XP_004856042.1/1-964 QSIRQGKLMAQPRDLGKAVMHQRPFLGRRPYRLLRYGESFGRSARLMCRMTHQKENPYKC *.:**** * **** ****:**** :*:******:***.****:**:*****:****:** ENSMUSP00000041821/1-960 GVCGKCFGRSRSLIRHQRIHTGEKPFKCPDCGKSFNDSSNFGAHQRVHTGEKPYRCRECG ENSRNOP00000020281/1-960 GVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHLRIHTGEKPYRCRECG ENSP00000331626/1-967 GVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECG ENSCPOP00000004695/1-966 SVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECG XP_004856042.1/1-964 SVCGKCFGRSRSLIRHQRIHTGEKPFKCLDCGKSFNDSSNFGAHQRIHTGEKPYRCGECG .*************************** *************** *:********* *** ENSMUSP00000041821/1-960 KCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRIHTEENPYKCGDCEKSFN ENSRNOP00000020281/1-960 KCFSQSSSLIIHQRTHTGEKPYQCEECGKSFTNSSHFSAHRRAHTGENPYKCGDCEKSFN ENSP00000331626/1-967 KCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCVDCEKSFN ENSCPOP00000004695/1-966 KCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCVDCEKSFN XP_004856042.1/1-964 KCFSQSSSLIIHQRTHTGEKPYQCGECGKSFTNSSHFSAHRRVHTGENPYKCMDCEKSFN ************************ ***************** ** ****** ******* ENSMUSP00000041821/1-960 NCARFREHQRIHNGEKPYTCAQCGKHFNKSSFLTKHREVHMREKLLPYSPSVYSPENLLK ENSRNOP00000020281/1-960 NCTRFREHRRIHTGEKPYTCAQCGKHFNKSSFLTKHREIHIREKPLPYSPSVYSPENLLK ENSP00000331626/1-967 NCTRFREHRRIHTGEKPYGCAQCGKRFSKSSVLTKHREVHVREKPLPHPPSLYCPENPHK ENSCPOP00000004695/1-966 NCTRFREHRRIHTGEKPYGCAHCGKRFSKSSVLTKHRDVHVREKFLPHTTSMYSPENSLK XP_004856042.1/1-964 NCTRFREHRRIHTGEKPYGCAHCGKRFGKSSVLAKHREVHVREKLLPHPLSMYPPE---K **:*****:***.***** **:***:*.***.*:***::*:*** **:. *:* ** * ENSMUSP00000041821/1-960 GKSAELRKTF ENSRNOP00000020281/1-960 ARSAELRKTF ENSP00000331626/1-967 GKTDEFRKTF ENSCPOP00000004695/1-966 GKTDDFRKT- XP_004856042.1/1-964 GKTDDFRKTF .:: ::***