CLUSTAL W(1.81) multiple sequence alignment ENSP00000343886/1-1220 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC ENSMUSP00000085775/1-1220 MGDMANSSIEFHPKPQQQREVPHVGGFGCTLAELRSLMELRGAEALQKIQEAYGDVSGLC ENSRNOP00000035695/1-1220 MGDMANSSIEFHPKPQQQREVPHVGGFGCTLAELRSLMELRGAEALQKIQEAYGDVSGLC ENSCPOP00000004590/1-1216 MGDMANSSIEFHPK----REAPQAGGFGCTLAELRALMELRGAEALQKIQEAYGDVSGLC XP_004874981.1/1-1220 MGDIANSSIEFHPKPQQQREAPQPGGFGCTLAELRALMELRGAEALQKVQEAYGSVSGLC ***:********** *:.*: ***********:************::****.***** ENSP00000343886/1-1220 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV ENSMUSP00000085775/1-1220 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV ENSRNOP00000035695/1-1220 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV ENSCPOP00000004590/1-1216 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV XP_004874981.1/1-1220 RRLKTSPTEGLADNANDLDKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV **************:***:***************************************** ENSP00000343886/1-1220 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ENSMUSP00000085775/1-1220 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ENSRNOP00000035695/1-1220 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ENSCPOP00000004590/1-1216 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK XP_004874981.1/1-1220 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK ************************************************************ ENSP00000343886/1-1220 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID ENSMUSP00000085775/1-1220 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKID ENSRNOP00000035695/1-1220 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKID ENSCPOP00000004590/1-1216 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKID XP_004874981.1/1-1220 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQGNDLKID *****************************************************.****** ENSP00000343886/1-1220 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE ENSMUSP00000085775/1-1220 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE ENSRNOP00000035695/1-1220 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE ENSCPOP00000004590/1-1216 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE XP_004874981.1/1-1220 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE ************************************************************ ENSP00000343886/1-1220 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL ENSMUSP00000085775/1-1220 KKDKKGKQQDGAMDSSQTRAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANVPKKEKSVL ENSRNOP00000035695/1-1220 KKDKKGKQQDGAMDSSQTRAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANVPKKEKSVL ENSCPOP00000004590/1-1216 KKDKKGKQQDGAMDSSQTRAKKQDGAVAMEMQPLKSAEGGEMEEREKKKASVPKKEKSVL XP_004874981.1/1-1220 KKDKKGKQQDGAMDSSQTRAKKQDGAVAMEMQPLKSAEGGETEEREKKKASVPKKEKSVL *************:****:********************** ********..******** ENSP00000343886/1-1220 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII ENSMUSP00000085775/1-1220 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFII ENSRNOP00000035695/1-1220 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFII ENSCPOP00000004590/1-1216 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFII XP_004874981.1/1-1220 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVDGRVWLAECTPVYVQYFVKFFII *************************************:**.******************* ENSP00000343886/1-1220 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT ENSMUSP00000085775/1-1220 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT ENSRNOP00000035695/1-1220 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT ENSCPOP00000004590/1-1216 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT XP_004874981.1/1-1220 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT ************************************************************ ENSP00000343886/1-1220 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG ENSMUSP00000085775/1-1220 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG ENSRNOP00000035695/1-1220 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG ENSCPOP00000004590/1-1216 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG XP_004874981.1/1-1220 NRMTVVQSYLGDTYYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG *************:********************************************** ENSP00000343886/1-1220 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG ENSMUSP00000085775/1-1220 NKTECALLGFVLDLKRDFQPVREQIPEDQLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG ENSRNOP00000035695/1-1220 NKTECALLGFILDLKRDFQPVREQIPEDQLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG ENSCPOP00000004590/1-1216 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIHLPDGSFRLFSKG XP_004874981.1/1-1220 NKTECALLGFMLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIHKPDGGFRLFSKG **********:*****************:******************: ***.******* ENSP00000343886/1-1220 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD ENSMUSP00000085775/1-1220 ASEILLKKCTNILNSNGELRGFRPRDRDDMVKKIIEPMACDGLRTICIAYRDFSAIQEPD ENSRNOP00000035695/1-1220 ASEILLKKCTNILNSNGELRGFRPRDRDDMVKKIIEPMACDGLRTICIAYRDFSAIQEPD ENSCPOP00000004590/1-1216 ASEILLKKCTNILNSSGELRSFRPRDRDDMVKKVIEPMACDGLRTICVAYRDFSAGQEPD XP_004874981.1/1-1220 ASEILLKKCTNILNSNGELRSFRPRDRDDMVKKVIEPMACDGLRTICVAYRDFSAGQEPD ***************.****.**********:*:*************:******* **** ENSP00000343886/1-1220 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG ENSMUSP00000085775/1-1220 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG ENSRNOP00000035695/1-1220 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG ENSCPOP00000004590/1-1216 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG XP_004874981.1/1-1220 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG ************************************************************ ENSP00000343886/1-1220 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS ENSMUSP00000085775/1-1220 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS ENSRNOP00000035695/1-1220 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS ENSCPOP00000004590/1-1216 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS XP_004874981.1/1-1220 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS ************************************************************ ENSP00000343886/1-1220 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM ENSMUSP00000085775/1-1220 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM ENSRNOP00000035695/1-1220 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM ENSCPOP00000004590/1-1216 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM XP_004874981.1/1-1220 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM ************************************************************ ENSP00000343886/1-1220 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA ENSMUSP00000085775/1-1220 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA ENSRNOP00000035695/1-1220 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA ENSCPOP00000004590/1-1216 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA XP_004874981.1/1-1220 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA ************************************************************ ENSP00000343886/1-1220 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP ENSMUSP00000085775/1-1220 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAP ENSRNOP00000035695/1-1220 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAP ENSCPOP00000004590/1-1216 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAP XP_004874981.1/1-1220 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLTIIFTLLFVGELFFDIDSGRNAP *************************************:********************** ENSP00000343886/1-1220 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI ENSMUSP00000085775/1-1220 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI ENSRNOP00000035695/1-1220 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI ENSCPOP00000004590/1-1216 LHSPPSEHYTIIFNTFVLMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI XP_004874981.1/1-1220 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGEHNVFDGIFSNPIFCTIVLGTFGIQIVI *****************:***************:************************** ENSP00000343886/1-1220 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD ENSMUSP00000085775/1-1220 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD ENSRNOP00000035695/1-1220 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD ENSCPOP00000004590/1-1216 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD XP_004874981.1/1-1220 VQFGGKPFSCSPLSTEQWLWCLFVGIGELVWGQVIATIPTSQLKCLKEAGHGPGKAEMTD *************************:***************************** **** ENSP00000343886/1-1220 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN ENSMUSP00000085775/1-1220 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKSCIHN ENSRNOP00000035695/1-1220 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKSCIHN ENSCPOP00000004590/1-1216 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKSSIHN XP_004874981.1/1-1220 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKSSIHN *******************************************************:.*** ENSP00000343886/1-1220 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKSA ENSMUSP00000085775/1-1220 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPPPNQNNNAIDSGIYLTTHATKSA ENSRNOP00000035695/1-1220 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPPPNQNNNAIDSGIYLTTHATKSA ENSCPOP00000004590/1-1216 FMVTPEFLINDYTHNIPLIDDTDVDENEERLRAALPPSPNQNNNAIDSGIYLTTHATKSA XP_004874981.1/1-1220 FMATPEFLINDYTRNIPLIDDTDVDENEERLRAALPPSPNQNNNAIDSGIYLTTHATKSA **.**********:*******************. **.*****************.**** ENSP00000343886/1-1220 TSSVFSSSPGSPLHSVETSL ENSMUSP00000085775/1-1220 TSSAFSSRPGSPLHSMETSL ENSRNOP00000035695/1-1220 TSSAFSSRPGSPLHSMETSL ENSCPOP00000004590/1-1216 TSSAFSSRPGSPLHSVETSL XP_004874981.1/1-1220 TSSAFSSRPGSPLHSMETSL ***.*** *******:****