CLUSTAL W(1.81) multiple sequence alignment


ENSCPOP00000004536/1-1329 -MDEEDSYYISQLKDVYNSCDTTGTGFLDLEELIQLCRKLHLDKQLPALLQTLLGDDLNA
XP_004874822.1/1-1258     -MDEEDNHYISQLKDVYNSCDSTGTGFLDQEELTELCRKLHLEKQLPALLQTLLGDDHIA
ENSP00000278886/1-1382    -MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFA
ENSMUSP00000105522/1-1394 MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLPALLHILLGDDRLA
ENSRNOP00000061689/1-1393 MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLPALLHILLGDGRLA
                            :**:.:*:*:*::**.***:******* :** :** ** *::***.**: ***:.  *


ENSCPOP00000004536/1-1329 RVTFEEFKEGLVTVLSSKANGDLGSKEAGSSQAAAVCAVPPKYVSGSKRYGRWSQPEWRA
XP_004874822.1/1-1258     RVNFEEFKEGLVTVLSSKAGGNPISEEAGSLQSAASYTVPPKYVSGSKWYGRWSQPEQRA
ENSP00000278886/1-1382    RVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCD
ENSMUSP00000105522/1-1394 RVNFEEFKEGFVAVLSSGSGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPELGD
ENSRNOP00000061689/1-1393 RVNFEEFKEGFVAVLSSATGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPELGD
                          **.*******:*:**** :.    .::..* ::*:  ::****:.*** *** * **   


ENSCPOP00000004536/1-1329 SGAEATRGPEQQARAGLKGQLCHAASLESVESLKSDEEAESPREPQEELFEAQGQLQTWG
XP_004874822.1/1-1258     SATKARCGPEQQARAGLKSQLHHSMSLESVESLKSNEEAESPREPQDELFEAQGQLQTWG
ENSP00000278886/1-1382    AATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWD
ENSMUSP00000105522/1-1394 SATATKYGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESAKEPQNELFEAQGQLRSWG
ENSRNOP00000061689/1-1393 SATTTKCGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESPKEPQNELFEAQGQLRSWG
                          :.: :   .***::..:*  * :: ******* **:*:***.:*.*:*********::*.


ENSCPOP00000004536/1-1329 SEVFGSIQKSCSSSCASPESRIQGIWEQLGVGSRGHLGEQELAVVCHSIGLLGLAEEELK
XP_004874822.1/1-1258     SEVFGSPQKSCSPLYASSESQVQDIWEQLGVGSRGHLDEQELAVVCQSIGLHGLEKEELK
ENSP00000278886/1-1382    SEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELE
ENSMUSP00000105522/1-1394 CEVFGTLRKSCSPSFSTPENLVQGIWHELGIGSSGHLNEQELAVVCRSIGLHSLEKQELE
ENSRNOP00000061689/1-1393 CEVFGTPRKSCSPSFNTPENQVQGIWHELGVGSSGHLNEQELAVVCRSIGLHGLEKQELE
                          .* **: :****.   :.*. ::.:*.:**:** ***.********:*:** .* ::**:


ENSCPOP00000004536/1-1329 DLFHKLDQDGDGRVSLAEFQLGLCHHKPMLLPESPLL----KPWSHSQGQVPEESGCHTA
XP_004874822.1/1-1258     DLFHKLDQDGDGRVSLEEFQLGLCSHKPSQIPESSTLVKPSRPWSHCQGQVPEESGCHTA
ENSP00000278886/1-1382    DLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHY--QVPEESGCHT-
ENSMUSP00000105522/1-1394 ELFSKLDQDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNRLWSHY--Q--EESGCHT-
ENSRNOP00000061689/1-1393 ELFSKLDRDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNGPWSHY--Q--EESGCHT-
                          :** ***:****:*** ******  *:*  :  *.        ***   *  ******* 


ENSCPOP00000004536/1-1329 ATTSSLASVSCGLRLFSSIDDGSGFALPEQVIATWAQEGIRSGREILQSLDFSLEEKVDL
XP_004874822.1/1-1258     TTTSSLVSMSCGLRLFSSIDDGSGFSLPEQVIATWAQEGIHSGREILQSLDFSLDEKVDL
ENSP00000278886/1-1382    TTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNL
ENSMUSP00000105522/1-1394 TTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQSLDFSVDEKVNL
ENSRNOP00000061689/1-1393 TTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQSLDFNVDEKVNL
                          :*****.*:...******:******::*:**:: *:****:.**********.::***:*


ENSCPOP00000004536/1-1329 LELTWALDNELLTVDSVIQQAALACYRQELSYLQEQVEQLARERDKARQDLERAERRSLE
XP_004874822.1/1-1258     LELTWALDNELLTVDSVIQQAALACYRQELSYHQEQVEQLVQERDKARQDLERAERRSLE
ENSP00000278886/1-1382    LELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLE
ENSMUSP00000105522/1-1394 LELTWALDNELLTVDGVIQQAALACYRQELSYHQGQVDQLVQERDKARQDLEKAEKRNLD
ENSRNOP00000061689/1-1393 LELTWALDNELLTVDGVIQQAALACYRQELNFHQGQVEQLVQERDKARQDLEKAEKRNLD
                          ***********:***..:********:***.: * **:**.:**********:**:*.*:


ENSCPOP00000004536/1-1329 LAREMDDSHTALEQLTERRIQCLEQDYQGRLSLLRAEVAAEQEQVWEQACRQNAALEQDL
XP_004874822.1/1-1258     LVREMDDSHTTLEQLTEQKIVCLEQDYRGRLNLLRAEVEAERELIWEQACRQSAMLEQDL
ENSP00000278886/1-1382    FVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDV
ENSMUSP00000105522/1-1394 FVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDV
ENSRNOP00000061689/1-1393 FVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDV
                          :.:****.*::******::*  *** *: **.***:**  *:* .**** ** * ** *:


ENSCPOP00000004536/1-1329 GLLRAEESRLRHRLGLAAKENSRLQQEILEVVGKLSDSEKLVLKLQGDLEFILKEKLEPQ
XP_004874822.1/1-1258     GHLRAEEASLRHRLGLASKENSRLQQEILEVVGKLSDSEKLVLKLQGDLEFMLREKLETQ
ENSP00000278886/1-1382    GRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQ
ENSMUSP00000105522/1-1394 GRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLEPQ
ENSRNOP00000061689/1-1393 GRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLEPQ
                          * *:***: **.:* ** *******:**:*** ******:*.*:** **:*:*::***.*


ENSCPOP00000004536/1-1329 GMELRGQEERFEAVLKEYELKCRDLQDQNDELQAKLERLRMRPPGNGSQQCPAGEPRHHS
XP_004874822.1/1-1258     GMELQAQEEQSAAVLKEYELKCRDLQDQNDELQAELESLQARLPQSQSWQCPAGDAGHHP
ENSP00000278886/1-1382    SAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNR--HSPSWSPDGRR
ENSMUSP00000105522/1-1394 SMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRLRLPRSR--QSPAGTPGTHR
ENSRNOP00000061689/1-1393 SMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRVRLPRSR--QSPSGTPGTHR
                          . ** .***:  *:*::**********:******:** *  * * .   :.*:  .  : 


ENSCPOP00000004536/1-1329 ---AGRCPQAGMFSNNSRPVSLETEIMVEEMREHCQELRTQLEAKVNAYEGEIKAMKNSF
XP_004874822.1/1-1258     ---------AGVYVDDSSPVSLETEILVEQMREHCQELRTQLEAKVNSYEREIEAMKNNF
ENSP00000278886/1-1382    RQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNF
ENSMUSP00000105522/1-1394 RRIPGRGPADNLFVGESTPVSLETEIMVEQMKEHYQELRMQLETKVNYYEKEIEVMKRNF
ENSRNOP00000061689/1-1393 RWTPGRGPADNLFVGESIPVSLETEIKMQQMKENYQELRMQLETKVNYYEKEIEVMKRNF
                                      : .:* ***:***: :::::*: *:** ***:*** ** ** .:*..*


ENSCPOP00000004536/1-1329 EKERMELEQVRQQEVTALEAQRADLEALCAKSQEVILGLREQLQEAAGSPKSVRAGPTSC
XP_004874822.1/1-1258     EKERMELEQARQQEVTVLEARRADLEVLCATSQEVILGLREQLRAAAGGPEASWAAMTSC
ENSP00000278886/1-1382    EKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPC
ENSMUSP00000105522/1-1394 EKDKKEMEQAFQLEVSVLEGQKADLEALYAKSQEVILGLKEQLQDAAQSPEPAPAGLAHC
ENSRNOP00000061689/1-1393 EKDKKEMEQAFQLEVSVLEGQKADLETLYAKSQEVILGLKEQLQDAARSPEPAPAGLAPC
                          **:: ::**. : **:.**.::**** *  .***** **:***: :* .*:.   . : *


ENSCPOP00000004536/1-1329 CAQALCDLTHWLELRTQRQYQGELRQIRQQAAAELSWMLSRLEAQHDTCYKSLVPRHQCE
XP_004874822.1/1-1258     CAPVLCDLAQQLDKHMWQQHQGELRQIRQEAAEELSRMLS----QHDIHCKSLVLRHQLE
ENSP00000278886/1-1382    CTQALCGLA--------LRHHSHLQQIRREAEAELSGELSGLGALPAR--RDLTLELEEP
ENSMUSP00000105522/1-1394 CAQALCTLAQRLEVEMHLRHQDQLLQIRQEAEEELNQKLSWLEAQHAACCESLSLQHQCE
ENSRNOP00000061689/1-1393 CAQALCTLAQRLGVEMHLRHQDQLLQIRREAEEELNQKLSWLEAQHAACCESLSLQHQCE
                          *: .** *:         :::..* ***::*  **.  **          ..*  . :  


ENSCPOP00000004536/1-1329 KDWLRQVLLQR------------------EAEVHVRCQEQQQRLQAALGKEQVQMCRCFA
XP_004874822.1/1-1258     KDRLQQVHLRR------------------EEEVLVRCQEQQQRLQVALGEEQAQMCRSFA
ENSP00000278886/1-1382    PQGPLPRGSQR------------------SEQLEL---ERALKLQPCASEKRAQMCVSLA
ENSMUSP00000105522/1-1394 KDQLLQTHLQRVKDLAAQLDLEKGRREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFT
ENSRNOP00000061689/1-1393 KDQLLQTHLQRVKDLAAQLDLEKGWREEREQEVLAHCRRQQLKLQAD-EEEQARICRSFT
                           :       :*                  . ::     .:  :**    :::.::* .::


ENSCPOP00000004536/1-1329 LERKRLEHAHCEQLEHLVQEAEVLQALLRGGAAATIGREWKGAPSHSSLCPG--------
XP_004874822.1/1-1258     LERKRLERAHREQVGSLVQEAEALRVLLQGGAAATTDKEQQGAPIPMSPCLD--------
ENSP00000278886/1-1382    LEEEELELARGKRVDGPSLEAE-MQALPKDGLVA--GSGQEGTRGLLPLRPGCGERPLAW
ENSMUSP00000105522/1-1394 LEKEKLEQTYREQVEGLVQEADVLRALLKNGTTV-VSDQQERTPSSMSLGPDSRQQPTAR
ENSRNOP00000061689/1-1393 LEKEKLEQTYREQVEGLVQEADVLRALLKNGTTV-VSDQQERIPGSMYPGPDSRQQPPTW
                          **.:.** :  :::     **: ::.* :.* ..  .   :          .        


ENSCPOP00000004536/1-1329 ---TPGGPEKLVGDWPG------QP-----CCVDAV--------SQQPPESLNHEQNCWG
XP_004874822.1/1-1258     ---IHGGTWEPVGDGPG------QP-----CCTDAV--------SRGLPESLDHEQSCWG
ENSP00000278886/1-1382    LA-PGDGRESEEAAGAGPRRRQAQD-----TEATQSPAPAPAPASHGPSERWSRMQPC--
ENSMUSP00000105522/1-1394 QAVSPDGRTGAPAEWPGPEKAEGRDFPGQLCSIDAMPSPTPTLLSRRSSENLGVRDNHQR
ENSRNOP00000061689/1-1393 QTVSPDGRTGAPAEWPGPGRADGRDLPGQLCSLDAVPSPTPTLLSRRSSESLDVRDNHQG
                               .*     .  .*      :                    *:  .*  .  :    


ENSCPOP00000004536/1-1329 LLDLEEVVSDPCEKGS------LRWPPGQ-SEGPD-----------SEKQAPSARATVSP
XP_004874822.1/1-1258     LMDAEETASVPFEKGP------PIQAPGQ-NKGAD-----------PEEPAPSARATVSP
ENSP00000278886/1-1382    --GVDGDI-VPKEPEPFGASAAGLEQPGA-RELPLLGTERDASQTQPRMWEPPLRPAASC
ENSMUSP00000105522/1-1394 PLNAEEGA-IPKEPEP-----SARTLTGQGQKLPL--------PVHPQMLEPSLGTTALD
ENSRNOP00000061689/1-1393 PLSAEEGA-VPKEPEP-----SARTLTGQDQKLPL--------PIQPQMLEPWLGPAAVD
                            . :     * *  .          .*   : .            ..   *   .:.  


ENSCPOP00000004536/1-1329 SQPD-----------------VREQPSQGVAGND-ALQT-WLQHHPGLLLLHPELPN---
XP_004874822.1/1-1258     SWPD-----------------VQELPSRG-TGEDGALQT-WLQHHSGPGT-TPEFPN---
ENSP00000278886/1-1382    RGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVAR-RGSLPSHLQ
ENSMUSP00000105522/1-1394 RKAA--------------SVGVQGQASEGPVGDGEGVQEAWLQFRGEATRMRPSLPC---
ENSRNOP00000061689/1-1393 RKPD--------------SVRVQGQASEGPTGDDKGVQETPLQLRGETARMRPSLPY---
                                               .:  .*.  .    .::    :          .:*    


ENSCPOP00000004536/1-1329 ---------------QTGETEAEIVERE-TGMKTKLLQLEDVVQAFEREADLRESDRVEL
XP_004874822.1/1-1258     ---------------PAGETEADMVEREKNDMKTKLLQLEDVVRALKREADSRENDREEL
ENSP00000278886/1-1382    LADPQGSWQEQLAAPEEGETKIAL-EREKDDMETKLLHLEDVVRALEKHVDLRENDRLEF
ENSMUSP00000105522/1-1394 ---------SELPNPQEATVMPAMSESEMKDVKIKLLQLEDVVRALEK-ADSRESYRAEL
ENSRNOP00000061689/1-1393 ---------SELPNPQEAKVMSVMSESEMNDVKTKLLQLEDVVRALEK-ADSRESYRAEL
                                           . .   : * *  .:: ***:*****:*::: .* **. * *:


ENSCPOP00000004536/1-1329 QRLSAANSLLKSDLERIQQELGAAEHMSNQQRREIEVLKRDKEKACSEMDE-LSIQNQKY
XP_004874822.1/1-1258     QRLSEENGLLKNDLERIQQKLGAAEHMSDMQRQEIEALKRDKEKVCFEMDEQLSIQNLKY
ENSP00000278886/1-1382    HRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEV-LNRQNQNY
ENSMUSP00000105522/1-1394 QRLSEENLVLKSDLGKIQLELETSESKNEVQRQEIEVLKRDKEQACCDLEE-LSTQTQKY
ENSRNOP00000061689/1-1393 QRLSEENSVLKSDLGKIQLELGTSESRNEVQRQEIEVLKRDKEQACFDLEE-LSTQTQKY
                          :***  * :**.** ::: :* ::*   : **:***.**:***:.* :::  *. *. :*


ENSCPOP00000004536/1-1329 KNEVLQLNCRVLQLEEVASAHQAQNEENLAAAQLLTQRLQEAARQEEQQCAQIRKLEAEL
XP_004874822.1/1-1258     KNEVSQLNCRVLQLEGVTSTHQAQNEENLAAAQLLTQRLEEVGRREEQQCAQIQKLETEL
ENSP00000278886/1-1382    KDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVEL
ENSMUSP00000105522/1-1394 KDEMSQLNCRVLQLEGEPSGLHTQKEENHGAIQVLMKKLEEAGCREEQQGDQIQNLKIEL
ENSRNOP00000061689/1-1393 KDEMSQLNCRILQLEGDSSGLHTQKEENHAAIQVLMKKLEEAECREKQQGDQIKHLKIEL
                          *::: *** *:***   .*  ::*:**:  : *:* : *:*.    :**  **::*. **


ENSCPOP00000004536/1-1329 LHLREEGQSVRPAQLGLTEDQEEGRTQRGLRRIRVKLPGLSGHQGSCSARSPDQIDGCRF
XP_004874822.1/1-1258     EHMSQQCQRLKLVRSELTESREEGQDQ---------------------------------
ENSP00000278886/1-1382    ECLNQEHQSLQLPWSELTQTLEESQDQ--VQGAHLRLRQAQAQH------LQE--VRLVP
ENSMUSP00000105522/1-1394 ERVNEECQYLRLSQAELTESLEESRSQ--LYSVQLRLEAAQSQHGRIVQRLQEQMSQLVP
ENSRNOP00000061689/1-1393 ERVNEECQRLRLSQAELTGSLEESQGQ--LHSVQLRLEAAQSQHDRIVQGLQEQMSQLVP
                            : :: * ::     **   **.: *                                 


ENSCPOP00000004536/1-1329 RAGLSCLGRKLLMVTLKI-----LHFGQFSLGIKPEEEPRDTMEGQAGEMEQLLQEKLDW
XP_004874822.1/1-1258     ----------------------------------EEQEQLDTRAGPAVEVELLLREKLD-
ENSP00000278886/1-1382    QDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDK
ENSMUSP00000105522/1-1394 GARVAELQHLLNVKEEEA-RRLSAQQEEYRQQLKAREDQVEDAEARLRNVEWLLQEKVEE
ENSRNOP00000061689/1-1393 GARVAELQHLLSLREEEA-ERLNAQQEEYKQQLKAREDQVEEAEARLHNVEWLLQEKVEE
                                                              ::  :       ::* **:**:: 


ENSCPOP00000004536/1-1329 VGRQLEKSARSGLLLKELYVENAQLTKALQVAEQKQWGAEKQNRILEEKVHALGTLISKL
XP_004874822.1/1-1258     ---QLEKTTRSGLLLKELYVENAHLTKALQVAEQKQWGAEKQKRILEEKVRALNTLISKL
ENSP00000278886/1-1382    LKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI
ENSMUSP00000105522/1-1394 LRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKM
ENSRNOP00000061689/1-1393 LRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKM
                             *:**.::*.***********:* :*:* :*:** ****:. :*****:**..*:*::


ENSCPOP00000004536/1-1329 APASLSV
XP_004874822.1/1-1258     APAALSV
ENSP00000278886/1-1382    APAALSV
ENSMUSP00000105522/1-1394 APASLSV
ENSRNOP00000061689/1-1393 APASLSV
                          ***:***