CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000036044/1-4505 -MGPRKPALRT---------------PL--LLLFLLLFLDTSVWAQDEVL--ENLSFSCP ENSRNOP00000039779/1-4743 -MGPQRPALRA---------------PL--LLLFLLLFLDTSVWAQD------------- ENSP00000233242/1-4563 MDPPRPALLAL------------LALPA------LLLLLLAGARAEEEML--ENVSLVCP ENSCPOP00000004440/1-4550 -MPPHSPCFLL------------SPKPE------VLVSPNAGAQAEDKLP--ENVNPSCP XP_004839128.1/1-4575 -MGARAAAQRVRVRARPQGTGMGRPRPALLLLLLLLLLLDAGARAEDEAPERESVSPSCP .: . * :*: :.. *:: ENSMUSP00000036044/1-4505 KDATRFKHLRKYVYNYEAESSSGVQGTADSRSATKINCKVELEVPQICGFIMRTNQCTLK ENSRNOP00000039779/1-4743 --ATRFKHLRKYVYSYEAESSSGVRGTADSRSATKINCKVELEVPQVCTLIMRTSQCTLK ENSP00000233242/1-4563 KDATRFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLK ENSCPOP00000004440/1-4550 KEATRFKHLRKYVYSYEAESSSGIPGKADSRSITKINCKVELEVPQLCSFVLKTSQCTLK XP_004839128.1/1-4575 KEATRFKHLRKYIYSYEAETSSGVPGTADSRSATKVSCKVELEVPQLCSFILKTSQCALK ********** *.****:***: *.***** *::.*********:* ::::*.**:** ENSMUSP00000036044/1-4505 EVYGFNPEGKALMKKTKNSEEFAAAMSRYELKLAIPEGKQIVLYPDKDEPKYILNIKRGI ENSRNOP00000039779/1-4743 EVYGFNPEGKALMKKTKNSEEFASAMSRYELKLAFPEGKRVALYPDLGEPNYILNIKRGI ENSP00000233242/1-4563 EVYGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGI ENSCPOP00000004440/1-4550 ELHGLNLEGKALLKKTKNSEDFAAAMSRHELRLAFPEGKRVFLYPEEEEPKHILNIKRGI XP_004839128.1/1-4575 EVYGFNPEGRVLLKKTKTSEAFAAAMSRYELRLAIPEGKQAVLYPEENEPAHILNIKRGI *::*:* **:.*:****.** **:****:**:**:****: ***: ** :******** ENSMUSP00000036044/1-4505 ISALLVPPETEEDQQELFLDTVYGNCSTQVTVNSRKGTVPTEMSTERNLQQCDGFQPIST ENSRNOP00000039779/1-4743 ISALLVPPETEEDKQVLFQDTVYGNCSTQVTVNSRKGTVATEMSTERNLQHCDGFQPIST ENSP00000233242/1-4563 ISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRT ENSCPOP00000004440/1-4550 VSALLAPPETEEDTQELFLDTVYGNCSTRVVVKTRKGNVATEMSTDRNLQECTGFQPSST XP_004839128.1/1-4575 ISALLVPPETEEAQQELFLDTVYGNCSTHTAVKTRKGSVATEMSTERNLQQCSGFQPAST :****.****** * ** *********: .*::***.*.**:**:*:* .* *:* * ENSMUSP00000036044/1-4505 SVSPLALIKGLVHPLSTLISSSQTCQYTLDPKRKHVSEAVCDEQHLFLPFSYKNKYGIMT ENSRNOP00000039779/1-4743 SVSPLALIKGLVRPLSTLISSSQSCQYTLEPKRKHVSEAICNEQHLFLPFSYKNKYGIMT ENSP00000233242/1-4563 GISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVA ENSCPOP00000004440/1-4550 GASPLALIRGLARPLSTLVSSSQSCQYTLDPKRKHVSEAVCREQHLFLPFSYKNKYGMMT XP_004839128.1/1-4575 GASPLALIKGLARPLSTLISSSQSCQYTLDPKRKHVSEATCKEQHLFLPFSYKNKYGMMT . ******:*:.:*****:****:*****:.*****:** * ***************::: ENSMUSP00000036044/1-4505 RVTQKLSLEDTPKINSRFFSEGTNRMGLAFESTKSTSSPKQADAVLKTLQELKKLSISEQ ENSRNOP00000039779/1-4743 HVTQKLSLEDTPKINSRFFRGGINQVGLAFESTKSTSPPKQADAVLKTLQELKKLSISEQ ENSP00000233242/1-4563 QVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQ ENSCPOP00000004440/1-4550 QVTQTLKLEDTPKINSRFFGEGALKVGLAFENTKSTFLPKQAEAVLKTLQELKKLTGFEP XP_004839128.1/1-4575 QVTQTLKLEDTPKINSRFFGGGTQKVGLAFESTKSPSLPKQAEAVLKTLQELKKLSTSEQ :***.*.************ * ::*****.***. ****:************: * ENSMUSP00000036044/1-4505 NAQRANLFNKLVTELRGLTGEAITSLLPQLIEVSSPITLQALVQCGQPQCYTHILQWLKT ENSRNOP00000039779/1-4743 NAQRANLFHKLVTELRGLSGEAITSLLPQLIEVSSPITLQALIQCGQPECYTHILQWLKT ENSP00000233242/1-4563 NIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKR ENSCPOP00000004440/1-4550 QVQRANLFSKLVTNLRGLSSEDITSLLPRLIEVSSPITLQALIQCGQPQCYTHVLQWLRS XP_004839128.1/1-4575 NAQRANLFNKLVTNMRGLSSEAITSLLPQLIEVSSPITLQALVQCGQPQCYTHVLQWLKS : ****** ****::***:.* :*****:*************:*****:* **:****: ENSMUSP00000036044/1-4505 EKAHPLLVDIVTYLMALIPNPSTQRLQEIFNTAKEQQSRATLYALSHAVNSYFDV-DHSR ENSRNOP00000039779/1-4743 EKAHPLLIDIVTYLMALIPNPSVQRLQEIFNTAKELQSRATLYALSHAVNSYYAIMDHSR ENSP00000233242/1-4563 VHANPLLIDVVTYLVALIPEPSAQQLREIFNMARDQRSRATLYALSHAVNNYHKT-NPTG ENSCPOP00000004440/1-4550 EKAHPLLIDVVTYLVALIPDPSAQMLRETFNIAKEQLSRATLYALSHMVNNYFET-TRTP XP_004839128.1/1-4575 EKAHPLLIDAVTYLVALIPDPSVQRLREIFSIAKEQQSRATLYALSHVANNYFEA-TRTV :*:***:* ****:****:**.* *:* *. *:: ********** .*.*. : ENSMUSP00000036044/1-4505 SPVLQDIAGYLLKQIDNECTGNEDHTFLILRVIGNMGRTMEQVMPALKSSVLSCVRSTKP ENSRNOP00000039779/1-4743 SPVLEDIAGYLMKQIDNECMGDEDRTFLILRVIGNMGRTMERVMPALKSSVLNCVRSTKP ENSP00000233242/1-4563 TQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKP ENSCPOP00000004440/1-4550 NQDLRDIANYLQEQIQDECAGDEEHTYLILRVIGNMGRTLDNITPTIKSSILRCIGSSKP XP_004839128.1/1-4575 DPDLQDIINYLQEQIQDQCAGDEDHAYLILRVIGNMGRTLESIAPMIKSSVLSCIRSPKG * ** .** :**:::* *:*: ::**********:*:: : * :***:* *: *.* ENSMUSP00000036044/1-4505 SLLIQKAALQALRKMELEDEVRTILFDTFVNGVAPVEKRLAAYLLLMKNPSSSDINKIAQ ENSRNOP00000039779/1-4743 SLQIQKAALQALRKMEMGDEVRTILFDTFVNDVAPVEKRLAAYLLLMRSPSSSDINKIAK ENSP00000233242/1-4563 SLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQ ENSCPOP00000004440/1-4550 SMLIQKAAIQALRKMQLGDEAQQLLLQTFVDSASPGDKRLAAYLTLMKKPSQSDIGRVIQ XP_004839128.1/1-4575 SVLIQKAAIQALRKMELGYEDRELLLQTFADSTSPVEKRLAAYLMLMKQPSQSDISSVIQ *: *****:******: : : :*::** :..:* :******* **:.**.:**. : : ENSMUSP00000036044/1-4505 LLQWEQSEQVKNFVASHIANILNSEELYVQDLKVLIKNALENSQFPTIMDFRKFSRNYQI ENSRNOP00000039779/1-4743 LLQWEQSEQVKNFVASHIANILNSEELYVQDLKNLIKNALVNSRLPTIMDFRKFSRNYQI ENSP00000233242/1-4563 ILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQL ENSCPOP00000004440/1-4550 LLPREENEQVKNFVVSHIANILSSEELYIGGLKALVKEALKDSQLPTIMDFSKFSRNYQF XP_004839128.1/1-4575 LLPQEESEQVKNFVASHVANILNSEELYVGDLKTLVKEALKDSQLPTVMDFRKYSRNYHV :* *:.*******.**:****.**** : .** *:*:** :*::**:*** *:****:. ENSMUSP00000036044/1-4505 SKSASLPMFDPVSVKIEGNLIFDPSSYLPRESLLKTTLTVFGLASLDLFEIGLEGKGFEP ENSRNOP00000039779/1-4743 SKSVSIPLFDPVSAKIEGNLVFDPSSYLPKESMLKTTLTVFGIASLDLFEIGLEGKGFEP ENSP00000233242/1-4563 YKSVSLPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEP ENSCPOP00000004440/1-4550 SKSVSLPSLDPVSAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLFEIGLEGKGFEP XP_004839128.1/1-4575 SKSVSLPSLDPVLAKIEGNLIFDPNNYLPKESMLKTTLTIFGFASADLFEIGLEGKGFEP **.*:* :**. .******:***..***:**:****** **:** **:*********** ENSMUSP00000036044/1-4505 TLEALFGKQGFFPDSVNKALYWVNGRVPDGVSKVLVDHFGYTTDGKHEQDMVNGIMPIVD ENSRNOP00000039779/1-4743 TLEALFGKQGFFPDSVNKALYWVNGQVPDRVSKVLVDHFGYTKDDKHEQDMVNGIMPIVD ENSP00000233242/1-4563 TLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVE ENSCPOP00000004440/1-4550 TLEALFGKQGFFPDSVSKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMINGIIPIVD XP_004839128.1/1-4575 TLEALFGKQGFFPDSVSKALYWVNGQVPDRVSQVLVDHFGYTKDDKHEQDMVSGIMPIVD ****************.********:*** **:*********.*.******:.**: *: ENSMUSP00000036044/1-4505 KLIKDLKSKEIPEARAYLRILGKELSFVRLQDLQVLGKLLLSGAQTLQGIPQMVVQAIRE ENSRNOP00000039779/1-4743 KLIKELKSKEIPEARAYLRILGKELGFVRLQDLQVLGKLLLNGAQTFRGVPQMIVQAIRE ENSP00000233242/1-4563 KLIKDLKSKEVPEARAYLRILGEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRK ENSCPOP00000004440/1-4550 KLIKDLKSRDLPEARAYLRILGKELSFFRLQDLRLLGRLLLSGVHALRGIPQMIGEALRE XP_004839128.1/1-4575 KLIRDLQSRDMPEARAYLRILGRELGFFKLQDLQLLGKLLLSGARTLQGIPQMISEAIRE ***::*:*:::***********.**.* *:**::**:*** *.::::*:***: :.:*: ENSMUSP00000036044/1-4505 GSKNDLFLHYIFMDNAFELPTGAGLQLQVSSSGVFTPGIKAGVRLELANIQAELVAKPSV ENSRNOP00000039779/1-4743 GSKDDLFLHYIFMENAFELPTGVGLQLQVSSSGVFTPGIKAGVRLELANIQAELVAKPSV ENSP00000233242/1-4563 GSKNDFFLHYIFMENAFELPTGAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSV ENSCPOP00000004440/1-4550 GWRNDLFLYYIFMDNTFELPTGMGLQLQVSSSGVTTLGTKAGVKLEMAKMQTDLVMRPSV XP_004839128.1/1-4575 GSEHDLFLHYIFMDNTFELPTGVGLQLQVSSSGIISPGSKAGLKLQVANMQADLLMKPAV * ..*:**:****:*:****** *****:****: : * ***::*::*::*::*: :*:* ENSMUSP00000036044/1-4505 SLEFVTNMGIIIPDFAKSSVQMNTNFFHESGLEARVALKAGQLKVIIPSPKRPVKLFSGS ENSRNOP00000039779/1-4743 SLEFVTNMGIIIPDFAKSGVQMNTNFFHESGLEARVALKAGQLKVIIPSPKRPVKLFSGS ENSP00000233242/1-4563 SVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGG ENSCPOP00000004440/1-4550 SVEFVTSIGIIMPDFARSGVRMNTNVFCGSSLEAHVALKAGELRFIVVSPKRPIKLFSIS XP_004839128.1/1-4575 SVEFVTNMGVIVPDFARSGVQMNTNFFHESGLEARVALKAGQLKVIIPSPKRPVKLFSGS *:****.:*:*:****:*.*:****.* *.***:******:*:.*: *****:**:* . ENSMUSP00000036044/1-4505 NTLHLVSTTKTEVIPPLVENRQSWSTCKPLFTGMNYCTTGAYSNASSTESASYYPLTGDT ENSRNOP00000039779/1-4743 NTLHLVSTTKTEVIPPLIENRKSWSTCKPFFTGMNYCTTGAYSNASSTESASYYPLTGDT ENSP00000233242/1-4563 NTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDT ENSCPOP00000004440/1-4550 NTLHLVSTTKTEVLPPLIDGKQSWVNCRPLIPGLNFCSTDAPSNASATESASYYPLTGNI XP_004839128.1/1-4575 NTLHLISTTKTEVIPPLMENRQSWSACRPFLTGLHYCTAGAYSNASSTESASYYPLTGDT *****:*******:***::.::** *: .:.*:::*::.* ****:*:*********: ENSMUSP00000036044/1-4505 RYELELRPTGEVEQYSATATYELLKEDKSLVDTLKFLVQAEGVQQSEATVLFKYNRRSRT ENSRNOP00000039779/1-4743 RYELELKPTGEVEQYSASATYELLKEDKSLVDTLKFLVQAEGVQQSEATAMFKYNRRSRT ENSP00000233242/1-4563 RLELELRPTGEIEQYSVSATYELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMT ENSCPOP00000004440/1-4550 RYGLELRPTGDVEQYSVGATYELQREENALVDRLKFAIQAEGKKTTEATLVFKYNRRSKT XP_004839128.1/1-4575 RYELELKPTGEVEQYSASATYELQREDKALVDRLKFVIQAEGVKQAEATLMFKYNRRSRT * ***:***::****. ***** :*:.:*** *** **** : :*** *****:* * ENSMUSP00000036044/1-4505 LSSEVLIPGFDVNFGTILRVNDESAKDKNTYKLILDIQNKKITEVSLVGHLSYDKKGDGK ENSRNOP00000039779/1-4743 LSSEVLIPGFDVNFGTILRVNDESSKDKNTYKLILDIQNKKITEVSVVGHVSYDKKGDGK ENSP00000233242/1-4563 LSSEVQIPDFDVDLGTILRVNDESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERK ENSCPOP00000004440/1-4550 LSSEMQIPDLDIDLGTILRVTDESSNDEKSYKLNLDFQNKKITEVAFTGHVSHDTNGEGK XP_004839128.1/1-4575 LSTEMQIPDLDVNLGTILRVSDESSKDKRSYKLNLDIQNKKITEVALSGHISHDTKGEGK **:*: **.:*:::******.***::.: :*:* **:********:. **:* *.: : * ENSMUSP00000036044/1-4505 IKGVVSIPRLQAEARSEVHTHWSSTKLLFQMDSSATAYGSTISKRVTWRYDNEIIEFDWN ENSRNOP00000039779/1-4743 VKGVVSIPRLQAEARSEVHTHWSPTKLLFQMDSSATAYGSTISKRVAWRYDNEKIEFDWN ENSP00000233242/1-4563 IKGVISIPRLQAEARSEILAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWN ENSCPOP00000004440/1-4550 IKGVISIPRLQAEARSEISTHWSPTKLLLHMDSSATAYGSAISKRVVWRYDDEKIEFQWN XP_004839128.1/1-4575 IKGVISIPRLQAEARSEILSHWSPTKLLLQMDSSATAYGSTVSKRVAWRYDDEKVEFEWN :***:************: :***.:***::**********::****.*:**:* :**:** ENSMUSP00000036044/1-4505 TGTNVDTKKVASNFPVDLSHYPRMLHEYANGLLDHRVPQTDVTFRDMGSKLIVATNTWLQ ENSRNOP00000039779/1-4743 TGTNVDTKKVASNFPVDLSRYPRMVHEYANGLLDHRVPQTDMTFRHMGSKLIV------- ENSP00000233242/1-4563 TGTNVDTKKMTSNFPVDLSDYPKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQ ENSCPOP00000004440/1-4550 TGTNVDTKKAAASFPVDPSDYLRSLHMHANKLLDHRIPQTGMTFSEMGSKLIVTTNTWLQ XP_004839128.1/1-4575 TGTNVDTKKVASNFPVDLSDYLRSLYMHANGLLHHRIPQTDMSFWDMGSKVIVTTNTWLQ ********* ::.**** * * : :: :** **.**:***.::* .:***:** ENSMUSP00000036044/1-4505 MATRGLPYPQTLQDHLNSLSELNLLKMGLSDFHIPDNLFLKTDGRVKYTMNRNKINIDIP ENSRNOP00000039779/1-4743 -------------DHLNGLSELNLPKVGLPDFHIPDNLFLKTDGRVKYTLNKNRIEIDIP ENSP00000233242/1-4563 KASGSLPYTQTLQDHLNSLKEFNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIP ENSCPOP00000004440/1-4550 EAANGLPYAQILQDHLSSLKELNLEKMWLPYFHLPDNLFLKSDGRIKYILNKNSIKVEIP XP_004839128.1/1-4575 EASSSLPYAQILQDHLSSLTELDLQKMSLPYFHIPDNLFLKSDGRVKYTLNKNSIEVDIP ***..*.*::* :: *. **:*:*****:***:** :*:* ::::** ENSMUSP00000036044/1-4505 LPLGGKSSKDLKMPESVRTPALNFKSVGFHLPSREVQVPTFTIPKTHQLQVPLLGVLDLS ENSRNOP00000039779/1-4743 LPLGGKSSKDLKVPESVRTPALNFKSVGFHLPSQEVQIPTFTIPKTHQLQVPLLGILDLS ENSP00000233242/1-4563 LPFGGKSSRDLKMLETVRTPALHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLS ENSCPOP00000004440/1-4550 LPFGGKSSRDLKMLETIRTPALSFKSLGFQLPSQEFQVPSFTIPEVYQLRVPLLGVLDLS XP_004839128.1/1-4575 LPFGGKSSKDLKMFDTIRTPALNFKSVGFYLPSREFHIPTFTIPELYQLRVPLLGVLDLS **:*****:***: :::***** ***:** ***:*.::*:****: :**:*****:**** ENSMUSP00000036044/1-4505 TNVYSNLYNWSASYTGGNTSRDHFSLQAQYRMKTDSVVDLFSYSVQGSGETTYDSKNTFT ENSRNOP00000039779/1-4743 TNVYSNLYNWSVSYTGGNTSRDHFSLQAQYRMKADSVVDLFSYSVQGSGETTYDSKSTFT ENSP00000233242/1-4563 TNVYSNLYNWSASYSGGNTSTDHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFT ENSCPOP00000004440/1-4550 TNVHSNLYNLSASYTGGNTSRDHFRLQARYHIKADSVVNLLSYSLQGSGETTYDHRNTFT XP_004839128.1/1-4575 TNVYSNLYNWSASYTGGNTSRDHFTLQARYHIKADSAVNLLSYSLQGSGETTYDHRNTFT ***:***** *.**:***** *** *:*:*::*:**.*:*:**.:********* :.*** ENSMUSP00000036044/1-4505 LSCDGSLHHKFLDSKFKVSHVEKFGNSPVSKGLLTFETSSALGPQMSATVHLDSKKKQHL ENSRNOP00000039779/1-4743 LSCDGSLHHKFLDSKFKVSHVEKFGNNPVSKGLLTFETSSALGPQMSATVQLDSKKKQHL ENSP00000233242/1-4563 LSYDGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHL ENSCPOP00000004440/1-4550 LSCDGSLRHQLLDSNVKLSHVEKIGNNPASKGVLTFDISSTWGPQMSASVHLDSKMKQQL XP_004839128.1/1-4575 LSCDGSLRHKFLDSNVKFSHVEKLGNNPASKGVLTFDASTTWGPQVSASVHLDSKKKQHL ** ****:*::***:.*.*****:**.*.***:* *: *:: ***:**:*:**** **:* ENSMUSP00000036044/1-4505 YVKDIKVDGQFRASSFYAQGKYGLSCERDVTTGQLSGESNMRFNSTYFQGTNQIVGMYQD ENSRNOP00000039779/1-4743 YVKDIKVDGQFRVFSLYAQGEYGLSYERDSMTGQMSGESNMKFNSTYFQGTNQIVGMYQD ENSP00000233242/1-4563 FVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYED ENSCPOP00000004440/1-4550 FVKDVKIDGQLRASSFYAEGTYGLTCQRNPTTGQLRGESNLRFNSSYLQGTNQMTGVYED XP_004839128.1/1-4575 YVRDVKIDGQFGASSFYAKGTYSLTCQGDPATGQLSGESDLSFNSSYLQGTNQITGRYED :*:::*:***: . *:**:* *.*: : : **:: ***:: ***:*:*****:.* *:* ENSMUSP00000036044/1-4505 GALSITSTSDLQDGIFKNTASLKYENYELTLKSDSSGQYENFAASNKLDVTFSTQSALLR ENSRNOP00000039779/1-4743 GMLSVTSTSDLQDGIFKNTASLKYENYELTLKSDSSGQYENFAASNKLDMTFSKQSALLR ENSP00000233242/1-4563 GTLSLTSTSDLQSGIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLR ENSCPOP00000004440/1-4550 GALSLTSTSNLQGGTLKNTASLKYENYELTLKSDTSGNYENLATSNKVDLTFSKQNALLR XP_004839128.1/1-4575 GALSLTSTSDLQGGTLKNTASLKYENYELTLKSDTNGKSENFAIRNRVDLTFSKQNALLH * **:****:**.* :******************:.*: :*:* *::*:***.*.***: ENSMUSP00000036044/1-4505 SEHQANYKSLRLVTLLSGSLTSQGVELNADILGTDKINTGAHKATLKIARDGLSTSATTN ENSRNOP00000039779/1-4743 SEHQANYKSLRLVTLLSGSLTSQGVELNADILGTDKINTGAHKSTLKIAQDGVSTSATTN ENSP00000233242/1-4563 SEYQADYESLRFFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTN ENSCPOP00000004440/1-4550 SEYQADYKSLKFFSLLAGSLNSQGVELNADILGTDKINAGAHKATLRITRDGISTSATTN XP_004839128.1/1-4575 SEYEADYKSLKFFSLLSGSLNSHGVELNADILGTDKVNTAAHKATLSIGRSGISTSATTN **::*:*:**::.:**:***.*:*:***********:*:.***:** * :.*:******* ENSMUSP00000036044/1-4505 LKYSPLLLENELNAELGLSGASMKLSTNGRFKEHHAKFSLDGRAALTEVSLGSIYQAMIL ENSRNOP00000039779/1-4743 LKYSPLLLENELNAELGLSGASMKLSTSGRFKEHHAKFSLDGRAALTEVSLGSIYQAMIL ENSP00000233242/1-4563 LKCSLLVLENELNAELGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMIL ENSCPOP00000004440/1-4550 LKYSPLFLENELNAALGLSGASMKLAANGRFREHSAKFSVDGKAALTEVSLASAYQAMLM XP_004839128.1/1-4575 LKYSPLFLENELNAELGLSGASMKFTANGRFREHSTKFTLDGKAALTEVSLGSVCQAMVL ** * *.******* *********:::.***:** :**::**:*****:**.* ***:: ENSMUSP00000036044/1-4505 GADSKNIFNFKLSREGLRLSNDLMGSYAEMKLDHTHSLNIAGLSLDFFSKMDNIYSGDKF ENSRNOP00000039779/1-4743 GADSKNVFNFKLSREGLKLSNDMMGSYAEMKLDHTHSLRISGLSLDFFSKMDNIYSGDKF ENSP00000233242/1-4563 GVDSKNIFNFKVSQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKF ENSCPOP00000004440/1-4550 GVDSKNVFSFRLSGEGLKVSNDLMGSYGEMTLDHANSLSIAGLSLEFSSKLDNIYSADKF XP_004839128.1/1-4575 GVDSKNIFNFRISGEGLKLSNDLKGSYGEITLDHANSLNTAGLSLEFSSKLDNIYSSDKF *.****:*.*::* ***::***: ***.*:.:**::** :****:* **:*****.*** ENSMUSP00000036044/1-4505 YKQNFNLQLQPYSFITTLSNDLRYGALDLTNNGRFRLEPLKLNVGGNFKGTYQNNELKHI ENSRNOP00000039779/1-4743 YKQNFNLQLQPYSFGITLSNDLKYDALVLTNNGRLRLEPLKLNVGGNFKGTYQNNELKHI ENSP00000233242/1-4563 YKQTVNLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHI ENSCPOP00000004440/1-4550 YKQNFNFQLQPFSLVTTLNNDLKYSALDLTSSGKLRLEPLKLNVGGNLKAAYQNNEIKHI XP_004839128.1/1-4575 YKQHFNFQLQPFSLVTTLNNDLKYSALGLTSSGKLRLEPLKLNVDGNLKGAYQNNEIKHI *** .*:****:*: **..**:*.** **..*::*******:* **:*.:*****:*** ENSMUSP00000036044/1-4505 YTISYTDLVVASYRADTVAKVQGVEFSHRLNADIEGLTSSVDVTTSYNSDPLHFNNVFHF ENSRNOP00000039779/1-4743 YTISYTDLVVASYRADTVATVQGVEFSHRLNADIEGLASSVDVTTSYSSDPLHFNNVFRF ENSP00000233242/1-4563 YAISSAAL-SASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRS ENSCPOP00000004440/1-4550 YTISYADL-SASYKADTLARIQGAEFSHRLSTGIAGLAASVDISTNYHSDSLRFNSAVHS XP_004839128.1/1-4575 FTISYVDI-SASYKASTIARIQGMQFSHQLNTGIAGLVASLDTSTNYHSDSLRFSSALHS ::** . : ***:*.*:* :** :***:*.:.* **.:::* :*.* **.*:*....: ENSMUSP00000036044/1-4505 SLAPFTLGIDTHTSGDGKLSFWGEHTGQLYSKFLLKAEPLALIVSHDYKGSTSHSLPYES ENSRNOP00000039779/1-4743 VLAPFTLGVDTHTSGDGKMSLWGEHTGQMYSKFLLKAEPLALTFSHDYKGSTSHNLLYKN ENSP00000233242/1-4563 VMAPFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRK ENSCPOP00000004440/1-4550 ALAPFTVAIDAHVNGNGKLALWGEHTGQLYSKFLLKAEPLALTFSHDYKGSTSHNLSSGK XP_004839128.1/1-4575 AVAPFALAINAHTNGNGKLALWGEHTGQLYSKFLLKAEPLALTFSHDYKGSTSHSLLSRE :***:: :::*..*:**:::*******:************: .********** * . ENSMUSP00000036044/1-4505 SISTALEHTVSALLTPAEQTSTWKFKTKLNDKVYSQDFEAYNTKDKIGVELSGR--ADLS ENSRNOP00000039779/1-4743 SVSTALEHTLSALLTPAEQTSSWKFKTSLNDKVYSQEFEAYNTKDKIGIELSGR--ADLS ENSP00000233242/1-4563 SISAALEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLT ENSCPOP00000004440/1-4550 SISAALDHRLSALLTPTEQTSTWKLKTQLNNHEYSQDFDAYNTKDKIGVELSGRGLADLT XP_004839128.1/1-4575 SIGMALDHKLSALLTPSEQTGTWKLKTQLNSNEYSQDFDAYNTKDKIGVELSGRGLADLT *:. **:* :******:***.:**:**.:*.: ***:::*********:**:** ***: ENSMUSP00000036044/1-4505 GLYSPIKLPFFYSEPVNVLNGLEVNDAVDKPQEFTIIAVVKYDKNQDVHTINLPFFKSLP ENSRNOP00000039779/1-4743 GLYSPIKVPFFYSEPVNVLNSLEINDAFDEPREFTIDAVVKYDKNQDVHTISLPFFQSLP ENSP00000233242/1-4563 LLDSPIKVPLLLSEPINIIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQ ENSCPOP00000004440/1-4550 VLDFPIKVPLLLSEPINVIDALQMKDAIEQPQEFTVVAFVKYDKNQDVHTISLPFLKTLP XP_004839128.1/1-4575 VLDSPIKVPFFLSEPINIIDTFRMKDTVQQPQEFTIAAAIKYDKNQDVHTISLPFFKSLP * ***:*:: ***:*::: :.:.*:.::*:***: * :*********:*.***:::* ENSMUSP00000036044/1-4505 DYLERNRRGMISLLEAMRGELQRLSVDQFVRKYRAALSRLPQQIHHYLNASDWERQVAGA ENSRNOP00000039779/1-4743 DYLERNRRGIISLLEAMKGELQRLSVDQFVRKYRVALSRLPQQIHDYLNASDWERQVAGA ENSP00000233242/1-4563 EYFERNRQTIIVVLENVQRNLKHINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHA ENSCPOP00000004440/1-4550 EYLERNRIIIITTLEIIQRELKRIDIDQFVKKYGAGLSKLPQQVSEHLNALDWERQIACA XP_004839128.1/1-4575 EYLEKNRLMIITALEAMQKELKSLNIDQFVGRYRAGLGKLPQQVNDYLTAFNWESQVASG :*:*:** :* ** :: :*: :.:**** :* ..*.:**** .:*.: :** *:: . ENSMUSP00000036044/1-4505 KEKITSFMENYRITDNDVLIAIDSAKINFNEKLSQLETYAIQFDQYIKDNYDPHDLKRTI ENSRNOP00000039779/1-4743 KEKLTSFMENYRITDNDVLIALDSAKINLNEKLSQLETYAIQFDQYIRDNYDAQDLKRTI ENSP00000233242/1-4563 KEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIQFDQYIKDSYDLHDLKIAI ENSCPOP00000004440/1-4550 KKKLTAFAENYRITENDLQTALNTVKINLNEKLSQFQTYVMQFDHYIINNYDLRDVKRAI XP_004839128.1/1-4575 KEKLTAFAENYRITENDVQTALNNAKISLNENLSQLQTYVIQFDQYIKDNYDLHDLKIAI *:*:*:: ::****:**: *:: .**.:**:***::** :***:** :.** :*:* :* ENSMUSP00000036044/1-4505 AEIIDRIIEKLKILDEQYHIRVNLAKSIHNLYLFVENVDLNQVSSSNTSWIQNVDSNYQV ENSRNOP00000039779/1-4743 AQIIDRIIEKLKMLDEQYHIRVNLAKSIHNLYLFVENVDLNQISSSGASWIQNVDTKYQI ENSP00000233242/1-4563 ANIIDEIIEKLKSLDEHYHIRVNLVKTIHDLHLFIENIDFNKSGSSTASWIQNVDTKYQI ENSCPOP00000004440/1-4550 AKIIDQITKRLKSLDERYQIRVTLVRTIHSLYLFVENVDFNKMASSTASWIQNVDTQYQI XP_004839128.1/1-4575 VRIIDRIIENLKILDEHYHIRENLVRTIHNAYLFIENIDFSKMGSSTASWIQNVDTQNQI ..***.* :.** ***:*:** .*.::**. :**:**:*:.: .** :*******:: *: ENSMUSP00000036044/1-4505 RIQIQEKLQQLRTQIQNIDIQQLAAEVKRQMDAIDVTMHLDQLRTAILFQRISDIIDRVK ENSRNOP00000039779/1-4743 RIQIQEKLQHLRTQIHNIDIQQLAAELKQQIEALDVPMHLDQLRTAILFQRISVIIERVK ENSP00000233242/1-4563 RIQIQEKLQQLKRHIQNIDIQHLAGKLKQHIEAIDVRVLLDQLGTTISFERINDILEHVK ENSCPOP00000004440/1-4550 RVQIQEKLEQIRTQIQNLDIQELAAKLKQQVEAIDIRKLLNQLRATIPVQKINTIIEHVK XP_004839128.1/1-4575 RIQIQEKLQQARTQIQNIDIQELAAKLKQQVEAIDTRALLNQVRTTIPFQRIKDIIEHVK *:******:: : :*:*:***.**.::*::::*:* *:*: ::* .::*. *:::** ENSMUSP00000036044/1-4505 YFVMNLIEDFKVTEKINTFRVIVRELIEKYEVDQHIQVLMDKSVELAHRYSLSEPLQKLS ENSRNOP00000039779/1-4743 YFVMNLIEDFKVTEKINTFRVIVRELIEKYEVDRQIQVLMDKSIELAHRYSLSEPLQKLS ENSP00000233242/1-4563 HFVINLIGDFEVAEKINAFRAKVHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLS ENSCPOP00000004440/1-4550 YFVINLINDFEVVEKINAFRAVAHELIKKYDIDRQIQVLIDKSVQLAHQYKLKDMVQKLS XP_004839128.1/1-4575 YIVISLIEDFEVTEKINAFRAIAHELIKKYEVDQQIQVLLDKSVQLARQYKLKDTVQKLS ::*:.** **:*.****:**. .:***::*::*::****:** ::**::*.*.: :**** ENSMUSP00000036044/1-4505 NVLQRIEIKDYYEKLVGFIDDTVEWLKALSFKNTIEELNRLTDMLVKKLKAFDYHQFVDK ENSRNOP00000039779/1-4743 NVLQQIEIKDYYDKLVGFIDDTVEWIKAVSFKNIIEELNRLIDMSVKKLKAFDYHQFVDK ENSP00000233242/1-4563 NVLQQVKIKDYFEKLVGFIDDAVKKLNELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDE ENSCPOP00000004440/1-4550 NALQQVDIKDCYEKLLVFIDDIIRELKEFSFKTIIEDVNHLLDILVKELRSFDYHQFVNE XP_004839128.1/1-4575 NLLQRVDMKDCYKKLLVFIDDIIRQLKAFSFKNFMEEVNQFLDALVKKLRSFDYHQFVDE * **::.:** :.**: **** :. :: .***. :*::*:: * :*:*::*******:: ENSMUSP00000036044/1-4505 TNSKIREMTQRINAEIQALKLPQKMEALKLLVEDFKTTVSNSLERLKDTKVTVVIDWLQD ENSRNOP00000039779/1-4743 TNSKIREMTQRINAEIQALELPQKTEALKLWVEDFKTTVSNSLEKLKDTKVTVVVDWLQD ENSP00000233242/1-4563 TNDKIREVTQRLNGEIQALELPQKAEALKLFLEETKATVAVYLESLQDTKITLIINWLQE ENSCPOP00000004440/1-4550 TNDTIREVIQLANS---YLDLPQKAEALKLFIEDVKVMLSAFLEKLKDTKITLFVDWLQN XP_004839128.1/1-4575 TNHKIREVTQIINAELQVLDLPQKAEALKLFVEDVRVMLSAFLEKLKDTKITVFVDWLQD ** .***: * *. *.**** ***** :*: :. :: ** *:***:*:.::***: ENSMUSP00000036044/1-4505 IL-----TQMKDHFQDTLEDVRDRIYQMDIQRELEHFLSLVNQVYSTLVTYMSDWWTLTA ENSRNOP00000039779/1-4743 GL-----AQIKAQFQDALEDVRDRIYQMDIQGELERCLSLVSQVYSTVVTYISDWWTLTA ENSP00000233242/1-4563 ALSSASLAHMKAKFRETLEDTRDRMYQMDIQQELQRYLSLVGQVYSTLVTYISDWWTLAA ENSCPOP00000004440/1-4550 ALNSAYFLPIKAKFQETLEDMRDRIYQMDIQHELERYLSLVGQVYNTLVTYISDWWGLTA XP_004839128.1/1-4575 ALNTAYLVPIKAKFQETLEDIRDRIYQMDIQQELERCLSLVGQVYSTLVTYVSDWWVLAA * :* :*:::*** ***:****** **:: ****.***.*:***:**** *:* ENSMUSP00000036044/1-4505 KNITDFAEQYSIQNWAESIKVLVEQGFIVPEMQTFLWTMPAFEVSLRALQEGNFQTPVFI ENSRNOP00000039779/1-4743 KNITDFAEQYSTQKWAESVKALVEQGFIVPEIQTFLGTMPAFEVSLHALQEANFQTPDFI ENSP00000233242/1-4563 KNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFI ENSCPOP00000004440/1-4550 KNLADLAEQYSIQAWAANVTALVEQGFTVPKIQTFLGTMPAFEVSLRALQQATFQTPDFV XP_004839128.1/1-4575 KNLTDFAEQYSIQGWAENVKALVEQGFTVPRIQLILGTVPAFEVSLRALQEASFQTPIFT **::*:***** * ** :..****** **.:: :* *:*******:***:..**** * ENSMUSP00000036044/1-4505 VPLTDLRIPSIRINFKMLKNIKIPLRFSTPEFTLLNTFHVHSFTIDLLEIKAKIIRTIDQ ENSRNOP00000039779/1-4743 VPLTDLRIPSIWINFKMLKNVKIPLRFSTPEFTLLNTFRVRSFTIDLLEIKAKIIRTIDQ ENSP00000233242/1-4563 VPLTDLRIPSVQINFKDLKNIKIPSRFSTPEFTILNTFHIPSFTIDFVEMKVKIIRTIDQ ENSCPOP00000004440/1-4550 VPLTDLKIPSVRINFKELKDIKIPSRFSTPQFTILNTFHIPSFTIDLKDIKVRIIRTIDQ XP_004839128.1/1-4575 VPLTDLRIPSVRINFKELKDIKIPPRFSTPEFTVLNTFHIPSFTVDFLEIKLKIIRTIDQ ******:***: **** **::*** *****:**:****:: ***:*: ::* :******* ENSMUSP00000036044/1-4505 ILSSELQWPLPEMYLRDLDVVNIPLARLTLPDFHVPEITIPEFTIPNVNLKDLHVPDLHI ENSRNOP00000039779/1-4743 MLSSELQWPLPEVYLRDLEMVNISLARLSLPDFHVPEITIPEFTIPNVNLKDLQVPDLHI ENSP00000233242/1-4563 MLNSELQWPVPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLNDFQVPDLHI ENSCPOP00000004440/1-4550 MLSSELRWPVPEVYLRDLKVENILPARLMLPDFSLPEITIPEFAIPNLNLSEFRVPDLHI XP_004839128.1/1-4575 MLSSEFQWPVPEVYVGDLKVEDILPARLFLPNFHLPEITIPEFLIPNLNLTEFQVPDLHI :*.**::**:*::*: **.: :* **: **:* :***:**** **.:**.:::****** ENSMUSP00000036044/1-4505 PEFQLPHLSHTIEIPAFGKLHSILKIQSPLFILDANANIQNVTTSGNKAEIVASVTAKGE ENSRNOP00000039779/1-4743 PEFQLPHLSCTTEIPAFGKLHSVLKIQSPLFILDASANIQNITTSENKAEIVASVTARGE ENSP00000233242/1-4563 PEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGE ENSCPOP00000004440/1-4550 PEFQLPPISHTAKIPAFGKLNSILKIQFPLFTIDAQANVHNVTISEHQAGIEAFIGAKGE XP_004839128.1/1-4575 PEFQLPPISHSAEIPALGKLNSILKIQSPLFTLDAKADIHNITTSEHQTGTEVSIAAKGE ****** :* : ::*::*** *:**** *** :**.*:: * * * ::: . : *:** ENSMUSP00000036044/1-4505 SQFEALNFDFQAQAQFLELNPHPPVLKESMNFSSKHVRMEHEGEIVFDGKAIEGKSDTVA ENSRNOP00000039779/1-4743 SKFEALNFDFQAQAQFLELNANPLVLKESVNFSSKHVRMEHEGKILVSGKALEGKSDTVA ENSP00000233242/1-4563 SKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVA ENSCPOP00000004440/1-4550 SKFEIFNFDFQANAQLLEPMTDPLLLKESMNFSSKYLRMGHGSEIVFSTNAIEGKSGTVA XP_004839128.1/1-4575 SKFEVFNFDFQANAQLLDPKTNPLLLKESMNFSSKHLRMEHKSEILFSINAIEGKSDTVA *::* :******:**: : .* ****::****::* * .:::. :*:****.*** ENSMUSP00000036044/1-4505 SLHTEKNEVEFNNGMTVKVNNQLTLDSHTKYFHKLSVPRLDFSSKASLNNEIKTLLEAGH ENSRNOP00000039779/1-4743 RLHTEKNTVEFNNGIVVKINNQFTLDSQTKYFHKLSVPRLDFSSKASLNNEIKTLLEAGH ENSP00000233242/1-4563 SLHTEKNTLELSNGVIVKINNQLTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLKAGH ENSCPOP00000004440/1-4550 SFHTEKNTLELKNGMIVKIKDQLTLDSLTKYSHKLNIPKLDFSSKAELINDVNTRLEAGH XP_004839128.1/1-4575 SFSTEKNTLELNNGVVVKMKGQLTLDNHMKYFHKLSIPKLDFSSKADLRNDLKTLLKVGH : **** :*:.**: **::.*:***. ** ***.:*:*****:*.* *:::* *:.** ENSMUSP00000036044/1-4505 VALTSSGTGSWNWACPNFSDEGIHSSQISFTVDGPIAFVGLSNNINGKHLRVIQKLTYES ENSRNOP00000039779/1-4743 MAWTSSGTGSWNWACPNFSDEGIHSSKISFIVDGPIASFGLSNNINGKHLRVVQKLTSES ENSP00000233242/1-4563 IAWTSSGKGSWKWACPRFSDEGTHESQISFTIEGPLTSFGLSNKINSKHLRVNQNLVYES ENSCPOP00000004440/1-4550 VTLTSSGAGSWKWACPNFSDEGTHESQISFTMKGPLASLELANKINSKHVRVTQNLAYES XP_004839128.1/1-4575 ITLTSSGAGSWKWACPSFSDEGTHESQINFTVEGPLASLGLANKINSKHLRVTQNLAYES :: **** ***:**** ***** *.*:*.* :.**:: . *:*:**.**:** *:*. ** ENSMUSP00000036044/1-4505 GFLNYSKFEVESKVESQHVGSSILTANGRALLKDAKAEMTGEHNANLNGKVIGTLKNSLF ENSRNOP00000039779/1-4743 GFLNYSRFEVESKVESQHVGSSILTAEGRALLGDAKAEMTGEHNANLNGKVIGTLKNSLF ENSP00000233242/1-4563 GSLNFSKLEIQSQVDSQHVGHSVLTAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLF ENSCPOP00000004440/1-4550 GFLNFSKFDITSDVESQHVGHSVLNAKGIALLDKGKVEITGDHNAHLNGKVIGTLKNSLF XP_004839128.1/1-4575 HFLNFSKFEIRSDVESQHVGHSILTAKGTALLGKGKAEITGDHSAHLSGKVIGTLKNSLF **:*:::: *.*:***** *:*.*:* **: ..*.*:** *.*:*.************ ENSMUSP00000036044/1-4505 FSAQPFEITASTNNEGNLKVGFPLKLTGKIDFLNNYALFLSPRAQQASWQASTRFNQYKY ENSRNOP00000039779/1-4743 FSAQPFEITASTNNEGNLKVSFPLKLTGKIDFLNNYALFLSPHAQQASWQLSTRFNQYKY ENSP00000233242/1-4563 FSAQPFEITASTNNEGNLKVRFPLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKY ENSCPOP00000004440/1-4550 VSAQPFEMTASANNEGNLKVSFPLKLTGKIDFLNNYALLVSPAAQQANWQASARFNQYKY XP_004839128.1/1-4575 ISAQPLEITASTNNEGNLKVSFPLRLTGKIDFLNNYALLLSPSAHQTSWQASAGFNQYKY .****:*:***:******** ***:*************::** *:*:.** *: ****** ENSMUSP00000036044/1-4505 NQNFSAINNEHNIEASIGMNGDANLDFLNIPLTIPEINLPYTEFKTPLLKDFSIWEETGL ENSRNOP00000039779/1-4743 NQNFSAINNEHNMEASIVMNGDANLDFLNIPLTIPEINLPYTRFTTPLLKDFSIWEETGL ENSP00000233242/1-4563 NQNFSAGNNENIMEAHVGINGEANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGL ENSCPOP00000004440/1-4550 NQNFSALNNENSIEAHVSINGDANLEFLNVPLTIPEMNVSYIALTTPSLKDFNIWEATGL XP_004839128.1/1-4575 NHNFSASNNENSIDAHVSINGDANLDFLNIPLTIPEMNLPYTTFKTPSLKDFSIWEETGL *:**** ***: ::* : :**:***:***:******:.:.* :.** ****.:** *** ENSMUSP00000036044/1-4505 KEFLKTTKQSFDLSVKAQYKKNSDKHSIVVPLGMFYEFILNNVNSWDRKFEKVRNNALHF ENSRNOP00000039779/1-4743 KEFLKTTKQSFDLSIKAQYKKNRDKHSVVIPLKMFYEFMLNNVNSWDRKFEKVRDNALHF ENSP00000233242/1-4563 KEFLKTTKQSFDLSVKAQYKKNKHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDF ENSCPOP00000004440/1-4550 KEFLKTTKQSVDLNVKIQYKKNKDKHSIAIPLGRFYKFINENVNSLDSYVANVRDNSLDF XP_004839128.1/1-4575 KEFLKTTKQSFDLNVKIQYKKNKDKHTIAVPLGVFYKFISQNVNSLDSYFENVRDNALDF **********.**.:* ***** .:*::. ** : :*: :.::* * . : *:*:*.* ENSMUSP00000036044/1-4505 LTTSYNEAKIKVDKYKTENSLNQPSGTFQNHGYTIPVVNIEVSPFAVETLASSHVIPTAI ENSRNOP00000039779/1-4743 LTASYNETKIKFDKYKTENSLNQPSRTFQNRGHTIPVLNIEVSPFAVETLASSHVIPKAI ENSP00000233242/1-4563 VTKSYNETKIKFDKYKAEKSHDELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAV ENSCPOP00000004440/1-4550 LTTAYKAVKFKWDEVRAEKSRNAPPRTFQYLGYTIPVISIEVSPFSAEIWPFSHVIPKAI XP_004839128.1/1-4575 LTTSYNELKIKLDEYKAERSLNKLPRTFPRPGYTIPIVNVEVTPFSVEMLPSGHMIPKAV :* :*: *:* *: ::*.* : . ** *:*:*::.:**:**: * . .:::*.*: ENSMUSP00000036044/1-4505 STPSVTIPGPNIMVPSYKLVLPPLELPVFHGPGNLFKFFLPDFKGFNTIDNIYIPAMGNF ENSRNOP00000039779/1-4743 RTPSVTIPGPNIIVPSYRLVLPSLQLPVFHIPRTLFKFSLPDFKKLSTIDNIYIPAMGNF ENSP00000233242/1-4563 SMPSFSILGSDVRVPSYTLILPSLELPVLHVPRNL-KLSLPDFKELCTISHIFIPAMGNI ENSCPOP00000004440/1-4550 NTSSSTVPSSDFSVPSYTLVLPSIELPELYIPRNLFKLSLPDLKELSDVSSLFIPAMGNM XP_004839128.1/1-4575 HTPSFTIPGFDFYVPSYMLSPPSIELPDLHIPRNLLKLSLPDFKGLSTVNNIFIPAMGNI .* :: . :. **** * *.::** :: * .* *: ***:* : :. ::******: ENSMUSP00000036044/1-4505 TYDFSFKSSVITLNTNAGLYNQSDIVAHFLSSSSFVTDALQYKLEGTSRLMRKRGLKLAT ENSRNOP00000039779/1-4743 TYDFSFKSSVITLNTNAGLYNQSDLVARFLSSSSFVTDALQYKLEGTSRLMRKKVLKLAT ENSP00000233242/1-4563 TYDFSFKSSVITLNTNAELFNQSDIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLAT ENSCPOP00000004440/1-4550 TYDFSFKSSVITLNTNAGLYNQSDIVAHFLSSSSFVIDALQYKLEGTLRLTRKRGLKLAT XP_004839128.1/1-4575 TYDFSFKSSVITLNTNAGLYNQSDIVAHFLSSSSFVIDALQYKLEGTSRLTRKRGLKLAT ***************** *:****:**::***** * ********** ** **: ***** ENSMUSP00000036044/1-4505 AVSLTNKFVKGSHDSTISLTKKNMEASVRTTANLHAPIFSMNFKQELNGNTKSKPTVSSS ENSRNOP00000039779/1-4743 AVSLTNKFLKGSHDSTISLTKKNMEASVKTTANLHAPIFTMNFKQELNGNTKSKPTVSSS ENSP00000233242/1-4563 ALSLSNKFVEGSHNSTVSLTTKNMEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSS ENSCPOP00000004440/1-4550 ALSLSNKFVEGSHDSTISFTKKNMEASLTTSAKVHVPVLRMNFKHELNGNTKSKPAASSS XP_004839128.1/1-4575 ALSLSNKFVEGSHDSTISITKKIMEASATTTAKVHIPVLRMNFKQELNGNTKSKPTVSSS *:**:***::***:**:*:*.* **.* *::: : *:: ****:**********:.*** ENSMUSP00000036044/1-4505 IELNYDFNSSKLHSTATGGIDHKFSLESLTSYFSIESFTKGNIKSSFLSQEYSGSVANEA ENSRNOP00000039779/1-4743 IELNYDFNSSKLHSAAKGGVDHKFSLESLTSYLSIESFTKGNIKGSFLSQEYSGSVANEA ENSP00000233242/1-4563 MEFKYDFNSSMLYSTAKGAVDHKLSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEA ENSCPOP00000004440/1-4550 IELKYDFNAPEMFPTAKGAIDHKLSLESLTSYFSIESSTKADIKGLVLSREYSGALASEA XP_004839128.1/1-4575 IELTYDFNSPKLFSSAKGAIDHKLSLESLTSYFSIESSTKGDIEGLVLSREYSGAIASEA :*:.****:. :..:*.*.:***:********:**** **.:::. .**:****::*.** ENSMUSP00000036044/1-4505 NVYLNSKGTRSSVRLQGASKVDGIWNVEVGENFAGEATLQRIYTTWEHNMKNHLQVYSYF ENSRNOP00000039779/1-4743 NVYLNSKGTRSSVRLQGASNFAGIWNFEVGENFAGEATLRRIYGTWEHNMINHLQVFSYF ENSP00000233242/1-4563 NTYLNSKSTRSSVKLQGTSKIDDIWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLF ENSCPOP00000004440/1-4550 STYLNSKATRSSVKLQGSSKVDGIWNVEVKENFAGEATPLRIYTMWEHSMKDRLRP--LL XP_004839128.1/1-4575 STYLSSKATRSSVKLQGSSKVDGIWNVEVKENFAGEATLRRMYAMWEHSMKNHLQPYSGF ..**.**.*****:***:*:. .***.** ******** *:* ***. ::*: : ENSMUSP00000036044/1-4505 FTKGKQTCRATLELSPWTMSTLLQVHVSQLSSLLDLHHFDQEVILKANTKNQKISWKGGV ENSRNOP00000039779/1-4743 DTKGKQTCRATLELSPWTMSTLLQVHVSQPSPLFDLHHFDQEVILKASTKNQKVSWKSEV ENSP00000233242/1-4563 FTNGEHTSKATLELSPWQMSALVQVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEV ENSCPOP00000004440/1-4550 STHGEHTSKATLELFPGAVSALIQVRARQLSSLFDIPHVGQEVVLNANTENQKFGWKSEV XP_004839128.1/1-4575 STHGEHTSKATLELSPGSVSALIQVRAREINSVLDIPHLGQEVALNANTKNQKFSWKSEV *:*::*.:***** * :*:*:**:. : ... *: ...*** *:*.*:***. **. * ENSMUSP00000036044/1-4505 QVESRVLQHNAQFSNDQEEIRLDLAGSLDGQLWDLEAIFLPVYGKSLQELLQMD-----G ENSRNOP00000039779/1-4743 QVESQVLQHNAHFSNDQEEVRLDIAGSLEGQLWDLENFFLPAFGKSLRELLQID-----G ENSP00000233242/1-4563 RIHSGSFQSQVELSNDQEKAHLDIAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIG ENSCPOP00000004440/1-4550 QIHSGTLKNSLQLSNDQKEARFDIAGTLEGHLHFLKFINLPVYDKSLWDLLKLDVTTSPR XP_004839128.1/1-4575 QGQLGTLQNHVQLSNDQKEARFDIAGSLEGRLHFLKFITLPVYDKSLWDLLKLDVTTSSQ : . :: .:****:: ::*:**:*:*:* *: : **.:.*** ::*::* ENSMUSP00000036044/1-4505 KRQYLQASTSLLYTKNPNGYLLSLPVQELADRFIIPGIKLN------------------- ENSRNOP00000039779/1-4743 KRQYLQASTSLHYTKNPNGYLLSLPVQELTDRFIIPGLKLN------------------- ENSP00000233242/1-4563 RRQHLRVSTAFVYTKNPNGYSFSIPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDLQ ENSCPOP00000004440/1-4550 KRQHLHAATALVYTKNPKGFPLSAPVQELTDKFVIPGLKLNDPYSDLITPTFQVPFTNLQ XP_004839128.1/1-4575 KRQYLHASTALVYTKNPKGYPFSVPVQELTDEFIVPGLKLN-----------------LQ :**:*:.:*:: *****:*: :* **: *:*.*::**:*** ENSMUSP00000036044/1-4505 ------DFSGVKIYKKLSTSPFALNLTMLPKVKFPGIDLLTQYSTPEGSSVPIFEATIPE ENSRNOP00000039779/1-4743 ------DFSGIKIYKKLSTSPFALNLTMLPKVKFPGVDLLTQYSKPEGSSVPTFETTIPE ENSP00000233242/1-4563 VPSCKLDFREIQIYKKLRTSSFALNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPE ENSCPOP00000004440/1-4550 VPSFKLDFSEIKIYKKLSSSPFAVSLPKLPKVKVPQVNVFTKYSEPGNSSVPYFEITVPE XP_004839128.1/1-4575 IPSYKLDFNEIRIYKKLSTSPFALNLPTLPKVKFPQVDVLTKYSEPEDSSVPFFEITIPD ** ::***** :*.**:.*. **:**.* ::::*:** * .* :* ** *:*: ENSMUSP00000036044/1-4505 IHLTVSQFTLPKSLPVGNTVFDLNKLANMIADVDLPSVTLPEQTIVIPPLEFSVPAGIFI ENSRNOP00000039779/1-4743 IQLTVSQFTLPKSFPVGNTVFDLNKLTNLIADVDLPSITLPEQTIEIPSLEFSVPAGIFI ENSP00000233242/1-4563 SQLTVSQFTLPKSVSDGIAALDLNAVANKIADFELPTIIVPEQTIEIPSIKFSVPAGIVI ENSCPOP00000004440/1-4550 VQLTVSQFTLPKSLRIAGAVLDLNKVASTIGDFELPTITVPEQTIEIPSIKFSVPAGVFL XP_004839128.1/1-4575 VQLTVSQFTLPKSLSVGSAVLDLSEVANMIGDFELPTITVPEQTIEIPSMKFSVPAGVFI :***********. . :.:**. ::. *.*.:**:: :***** **.::******:.: ENSMUSP00000036044/1-4505 PFFGELTARAGMASPLYNVTWSAGWKTKADHVETFLDSMCTSTLQFLEYALKVVETHKIE ENSRNOP00000039779/1-4743 PFFGELTAHVGMASPLYNVTWSTGWKNKADHVETFLDSTCSSTLQFLEYALKVVGTHRIE ENSP00000233242/1-4563 PSFQALTARFEVDSPVYNATWSASLKNKADYVETVLDSTCSSTVQFLEYELNVLGTHKIE ENSCPOP00000004440/1-4550 PLFGALTARFGVASPLYNATWNVGLKNNADHVETFLDSTCSSTLQFLEYDLNVVGTYKID XP_004839128.1/1-4575 PFFGALTARFGVASPLYNATWNVGLKNKADHVETFLDSTCSSTLQFLEYDLNVVGTHSLE * * ***: : **:**.**... *.:**:***.*** *:**:***** *:*: *: :: ENSMUSP00000036044/1-4505 EDLLTYNIKGTLQHCDFNVEYNEDGLFKGLWDWQGEAHLDITSPALTDFHLYYKEDKTSL ENSRNOP00000039779/1-4743 NDKFIYKIKGTLQHCDFNVKYNEDGIFEGLWDLEGEAHLDITSPALTDFHLHYKEDKTSV ENSP00000233242/1-4563 DGTLASKTKGTFAHRDFSAEYEEDGKYEGLQEWEGKAHLNIKSPAFTDLHLRYQKDKKGI ENSCPOP00000004440/1-4550 DAMLSYKIKGTLDHSDLSAEYEEDGKYKGLEDWEGEASLDFRSPAFTELHLRYQEDRNSM XP_004839128.1/1-4575 DGMLICKIKGTLAHRDFSAEYKEVDKYKGLKAWEEDVNLDILSPAFTELHLRYREDENSM : : : ***: * *:..:*:* . ::** : .. *:: ***:*::** *::*...: ENSMUSP00000036044/1-4505 SASAASSTIGTVGLDSSTD-DQSVELNVYFHPQSPPEKKLSIFKTEWRYKESDGERYIKI ENSRNOP00000039779/1-4743 SASAASPAIGTVSLDASTD-DQSVRLNVYFRPQSPPDNKLSIFKMEWRDKESDGETYIKI ENSP00000233242/1-4563 STSAASPAVGTVGMDMDED-DDFSKWNFYYSPQSSPDKKLTIFKTELRVRESDEETQIKV ENSCPOP00000004440/1-4550 SSSAASPAIGTVGLDLETEGDRSFKCNLYFQPQSSSDKKLTILKMDWKYQESGDKTQMRF XP_004839128.1/1-4575 SFSAASPAVGTVGLDLETEGDRSFKGNLYFQPQSSPGRKLNIFKTEWRYQESDDKIQMKF * ****.::***.:* . : * . *.*: ***.. .**.*:* : : :**. : ::. ENSMUSP00000036044/1-4505 NWEEEAASRLLGSLKSNVPKASKAIYDYANKYHLEY-------VSSELRKSLQVNAE--- ENSRNOP00000039779/1-4743 NWEEEAAFRLLDSLKSNVPKASEAVYDYVKKYHLGH-------ASSELRKSLQNDAE--- ENSP00000233242/1-4563 NWEEEAASGLLTSLKDNVPKATGVLYDYVNKYHWEHTGLTLREVSSKLRRNLQNNAEWVY ENSCPOP00000004440/1-4550 NWEEEAASRLLSSLKDNVPKATGALYDYADKYHQEYTGLNLKDASAKLKRSVRESAEGAF XP_004839128.1/1-4575 NWEEEAASRFLGSLKDNVPKATGAFYDYVDKYHQEYTGLSLKDASSKLRRSLRESAEGAY ******* :* ***.*****: ..***..*** : .*::*::.:: .** ENSMUSP00000036044/1-4505 -HARRMVDEMNMSFQRVA----------RDTYQNLYEEMLAQKSLSIPENLKKRVLDSIV ENSRNOP00000039779/1-4743 -HAIRMVDEMNVNAQRVT----------RDTYQSLYKKMLAQESQSIPEKLKKMVLGSLV ENSP00000233242/1-4563 QGAIRQIDDIDVRFQKAASGTTGTYQEWKDKAQNLYQELLTQEGQASFQGLKDNVFDGLV ENSCPOP00000004440/1-4550 RTARRQLEELEAEVQTAASSTTGAYQEWKKNAQDLYQDLLAEEGQNNSQRLKDEVFDSLI XP_004839128.1/1-4575 QRARRQINKMDVGLQRAASSTIGTYQEWKEKAQDLYQELLAEEGQASSQRLKDKVFDSLF * * ::.:: * .: :.. *.**:.:*:::. : **. *:..:. ENSMUSP00000036044/1-4505 HVTQKYHMAVMWLMDSFIHFLKFNRVQFPGYAGTYTVDELYTIVMKETKKSLSQLF---- ENSRNOP00000039779/1-4743 RITQKYHMAVTWLMDSVIHFLKFNRVQFPGNAGTYTVDELYTIAMRETKKLLSQLF---- ENSP00000233242/1-4563 RVTQEFHMKVKHLIDSLIDFLNFPRFQFPGKPGIYTREELCTMFIREVGTVLSQVYSKVH ENSCPOP00000004440/1-4550 QVTHKYHKAAKHLIHSFIDFLKLTRIQLPGMNGTYTRDELCTIVMREIGKILSQVYSNLQ XP_004839128.1/1-4575 QATQEARMAAKCMMDSSIGFLQLTRIQLPGIAGTYTGEELCTMVIKEIGKVLSWAYSNIH : *:: : . ::.* * **:: *.*:** * ** :** *: ::* . ** : ENSMUSP00000036044/1-4505 NGLGNLLSYVQNQVEKSRLINDITFKCPFFSKPCKLKDLILIFREELNILSN------IG ENSRNOP00000039779/1-4743 NGLGHLFSYVQDQVEKSRVINDITFKCPFSPTPCKLKDVLLIFREDLNILSN------LG ENSP00000233242/1-4563 NGSEILFSYFQDLV----------ITLPFELRKHKLIDVISMYRELLKDLSKEAQEVFKA ENSCPOP00000004440/1-4550 NGLEKLLSYTQDLV----------IELPYDAGRYKLTEVILNCRKLLEYLSQEVQKALID XP_004839128.1/1-4575 SELEKLLSYAQDLVEKSELIKDLQITFPFYSESYKLTEVILKSRKLLEFLSKNVQDVFID . *:** *: * : *: ** ::: *: *: **: ENSMUSP00000036044/1-4505 QQDIKFTTILSSLQGFLERVLDIIEEQIKCLKDNESTCVADH----INMVFKIQVPYAFK ENSRNOP00000039779/1-4743 QQDINFTTILSDFQSFLERLLDIIEEKIECLKNNESTCVPDH----INMFFKTHIPFAFK ENSP00000233242/1-4563 IQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMKFTYLINYIQDEINTIFSDYIPYVFK ENSCPOP00000004440/1-4550 LQSIKFSEKLSDLQSFLQIVFQEIEAEIKSLKETRLSHLTNT----VREVINTYIPFTYG XP_004839128.1/1-4575 LQSIKLSETLGDLQSSLQIIFERIEEEIKYLKETRFIHPINA----IDTIFNTYIPFAFR *.:: : * .:*. *: ::: ** :*: **: . : : .:. :*:.: ENSMUSP00000036044/1-4505 SLREDIYFVLGEFNDFLQSILQEGSYKLQQVHQYMKALREEYFDPSMVGWTVKYYEIEEN ENSRNOP00000039779/1-4743 SLRENIYSVFSEFNDFVQSILQEGSYKLQQVHQYMKAFREEYFDPSVVGWTVKYYEIEEK ENSP00000233242/1-4563 LLKENLCLNLHKFNEFIQNELQEASQELQQIHQYIMALREEYFDPSIVGWTVKYYELEEK ENSCPOP00000004440/1-4550 VLKEGLSLHINELVEFY---LQTTSQGLLQIHHYVKALREEYFDPSIIGWTVKYYELEEK XP_004839128.1/1-4575 VLKESLYLNLTKFNEAVQNNLQVASQGLQQTHQYLKALREEYFDPSIVGWTVKYYALEEK *:*.: : :: : ** * * * *:*: *:********::******* :**: ENSMUSP00000036044/1-4505 MVELIKTLLVSFRDVYSEYSVTAADFASKMSTQVEQFVSRDIREYLSMLTDINGKWMEKI ENSRNOP00000039779/1-4743 MVDLIKTLLAPLRDFYSEYSVTAADFASKMSTQVEQFVSRDIREYLSMLADINGKGREKV ENSP00000233242/1-4563 IVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQVEQFLHRNIQEYLSILTDPDGKGKEKI ENSCPOP00000004440/1-4550 IVDLIKHLAASLKDLHSMYTAHATKFASQLSTQVERF----VQEYLSIFVDADGKGRVKI XP_004839128.1/1-4575 MVDLVMDLVIALKNLHSTYTAYAASSASQLSALVEQFVHKDVQEYLSILADADRRGKEKI :*.*: * .:::.:* * . *:. :*::*: **:* ::****::.* : : *: ENSMUSP00000036044/1-4505 AELSIVAKETMKSWVTAVAKIMSDYPQQFHSNLQDFSDQLSSYYEKFVGESTRLIDLSIQ ENSRNOP00000039779/1-4743 AELSIVVKERIKSWSTAVAEITSDYLRQLHSKLQDFSDQLSGYYEKFVAESTRLIDLSIQ ENSP00000233242/1-4563 AELSATAQEIIKSQAIATKKIISDYHQQFRYKLQDFSDQLSDYYEKFIAESKRLIDLSIQ ENSCPOP00000004440/1-4550 AELSNTTQEGIQTLTTAMKEIVSDYQKQFTSKLQELSDQFSDYHEKVIALFQGLIDLSIE XP_004839128.1/1-4575 AELSNSAQQVIKTLTTAMKEIVSDYLEQFISKLQEFLDQFPDYYEKFIAESQRLIDLAIQ **** .:: ::: * :* *** .*: :**:: **:..*:**.:. ****:*: ENSMUSP00000036044/1-4505 NYHVFLRYITELLRKLQVATANNV------------------------------------ ENSRNOP00000039779/1-4743 NYHMFLRYIAELLKKLQVATANNGLLKRGDFEAAVKLGIACLYNEGLSVSDEAYAEVNGL ENSP00000233242/1-4563 NYHTFLIYITELLKKLQSTTVM-------------------------------------- ENSCPOP00000004440/1-4550 NYHMLLRYITEVLAKLQAATAKGG------------------------------------ XP_004839128.1/1-4575 SYHVILSYITELLKKLQAATASGG------------------------------------ .** :* **:*:* *** :*. ENSMUSP00000036044/1-4505 ----------------SPYI---------------------------------------- ENSRNOP00000039779/1-4743 KASRFFSMDERLNMGSDPFIWLSICPPCFRKLRDFAGKGCWEAQPALAKDCAGGSQLGLE ENSP00000233242/1-4563 ----------------NPYM---------------------------------------- ENSCPOP00000004440/1-4550 ----------------SPSI---------------------------------------- XP_004839128.1/1-4575 ----------------NPYV---------------------------------------- .* : ENSMUSP00000036044/1-4505 ------------------------------------------------------------ ENSRNOP00000039779/1-4743 GKAFSESVCQLFQASQAVNKQQIFSVQKGLSDTVRYILIGWLVEVAPMKDFTSLCLHLTV ENSP00000233242/1-4563 ------------------------------------------------------------ ENSCPOP00000004440/1-4550 ------------------------------------------------------------ XP_004839128.1/1-4575 ------------------------------------------------------------ ENSMUSP00000036044/1-4505 ---------KLAQ----------------------------------------------- ENSRNOP00000039779/1-4743 ECVGRYLQRKLVPRYKLQLLGIACMVICTWFISKEILTIREAVRLTDNTYKYKDLVRVKR ENSP00000233242/1-4563 ---------KLAP----------------------------------------------- ENSCPOP00000004440/1-4550 ---------QLTS----------------------------------------------- XP_004839128.1/1-4575 ---------KLAP----------------------------------------------- :*. ENSMUSP00000036044/1-4505 ---------------------------------------GELMITF-------------- ENSRNOP00000039779/1-4743 EIISALEGKIRIPTVVDYKEVLLTLVPVTPRTQYLCSFLCELTLSVYTPAHLASAALLLA ENSP00000233242/1-4563 ---------------------------------------GELTIIL-------------- ENSCPOP00000004440/1-4550 ---------------------------------------GELIITI-------------- XP_004839128.1/1-4575 ---------------------------------------GELTITY-------------- ** : ENSMUSP00000036044/1-4505 --------- ENSRNOP00000039779/1-4743 RLMHGQTQP ENSP00000233242/1-4563 --------- ENSCPOP00000004440/1-4550 --------- XP_004839128.1/1-4575 ---------