CLUSTAL W(1.81) multiple sequence alignment ENSP00000368876/1-1019 MGTRDDVP-EAKVLVPVAVYCGSIPRTSAGPRVLPPGSINSSLP-HGEGSLQPEPRALLN ENSMUSP00000114359/1-1022 LPLSSQASFAAKVPAPVAVYCGSVPRTSVGLRAPPPGGIDSSLLAHDEASLQPVSSVLPS ENSRNOP00000038699/1-998 MDTRDDVT-LAKVVAPVAVYCGSVPRTSVGLRAPPPGSIDSSEGTFEEASPQPVSSVLPS ENSCPOP00000004219/1-1020 MGTRDDVP-PAKVLAPVAVYCGSVPRTSAGPHMTLPGSISSTLPAYSPASIQPAPSVLLN XP_004839295.1/1-1004 MGTRDDVP-PAEGLAPVAVYCGSVPRTSAGPCAPLPGSISSSVP-HGFSSDQPVPSVLRG : .:.. *: .********:****.* **.*.*: . .* ** . .* . ENSP00000368876/1-1019 NEEPSQLLRGLGQLGGLKLDTPSKGWQARNGHPRNLRALSLGDQPLVLLPSPESEANSVA ENSMUSP00000114359/1-1022 SEKPSQLSREHEDQSSLMLNAPLKGWQARNGYPRGLGVLPLGHHLGAAIPSLESEASSVA ENSRNOP00000038699/1-998 SEKPSQLLSGHEDQSSLTLDAPLKGWQARNGYPRNLRALPLGPHPLAVIPSLESEASSVA ENSCPOP00000004219/1-1020 SEKPSQPLGGCGDPGSVTLDGPLKGWQARNGHPGDLGALSLGPHPQMSVTLLESEASSVA XP_004839295.1/1-1004 HEKPAQLSSGCGDSGSIIVGAPLKGWQARNGHPRDLGALSLGLLPRVSVSLLESEANSAA *:*:* : ..: :. * ********:* .* .*.** :. ****.*.* ENSP00000368876/1-1019 RDTIQIKDKLKKRRLSEGLAASSRASLDPGGGPQGVPLHSTIPRATSQRLLRVPRPMPLI ENSMUSP00000114359/1-1022 RDTIQIKDKLKKRRLSEGMAASSQASLDPVGGPRGVPLRSTIPRTTSQRLLRVPRPMPPI ENSRNOP00000038699/1-998 RDTIQIKDKLKKRRLSEGMAASSQVSLDPVGGPKGVPLRSTIPRTASQRLLRVPRPMPPI ENSCPOP00000004219/1-1020 RDTTQIKDKLKKRRLSEGMAASLRASLDPGGGPKGVPLRSTIPRTTSQRLLGVPRPMPPI XP_004839295.1/1-1004 RDTTQIKDKLKKRRLSEGMAASLRASLDPGGGPRGAPLRSTVPRTTSQRLLRVPRPMPPI *** **************:*** :.**** ***:*.**:**:**::***** ****** * ENSP00000368876/1-1019 QSIPTTPEASGVKEKGLDLPGSIPGPHELRPGAQEAQISWQYLHCNDEKMQKSLGAIVIP ENSMUSP00000114359/1-1022 QSIPTTPEANSAKEKDLDPPGGRQDLQDPGASAQEVQISRQYLHCADEKMHKSLGGLVIP ENSRNOP00000038699/1-998 QSIPTTPEANSAKEKDLDPPGGRPG-----AGAQEVQISRQYLHCADEKMHKSLGGIVIP ENSCPOP00000004219/1-1020 QSIPTTPEASGAKEKDMDPPGGSQGAQELSADAQGVRICAQYLHCNDESMRGSLGGIVIP XP_004839295.1/1-1004 QSIPTTPEASGAKEKGLDPPGSGQGAQELRAGAQEVQISPQYLHCNDEKMQKSLGGIVIP *********...***.:* **. . ..** .:*. ***** **.*: ***.:*** ENSP00000368876/1-1019 PIPKARTVAATPSRVPGSLPSPLPPGQGVLTGLRAPRTRLARGSGPREKTPASLEPKPLA ENSMUSP00000114359/1-1022 PIPKARMPTGTSSCRPGSLPSPLCPSQDVLMGPKAPHTRLTCENGPLEKTPKSPASKPLV ENSRNOP00000038699/1-998 PIPKARMPTGTSSCRPGSRSSPLCPGQDGLMGTRAPPTRLTCENGPLEKTPKSLAPKPLV ENSCPOP00000004219/1-1020 PIPKAGASVETSSGRPGSLSSPWAPGQDVLMGTRPPNTRLAQECGPQEKTPKSPEPKPLA XP_004839295.1/1-1004 PIPKAGVSVGTSPRRPGPLPSPSAPGQDILTGTRPLHTRLLQESGLREKTPKSPEPKPLA ***** . *.. **. .** *.*. * * :. *** * **** * .***. ENSP00000368876/1-1019 SPIRDRPA-AAKKPALPFSQSAPTLTAFSFDCAREACPPLKEEDQKEIGTKIQVTISKSA ENSMUSP00000114359/1-1022 PVVKAKSA-EAPETSLASSQSTFTLTAFS-SHAKETRSLENEEDQKESSTKVQVTISKSA ENSRNOP00000038699/1-998 PAVKAKSA-EAPPTSLASSQSTFTLTAFS-SHAKETRSLTNEEDQRESSTKVQVTISKSA ENSCPOP00000004219/1-1020 PPIRDRSATVASKKSLASSQSAPVLTAFSLGHAKEAHPLPKEEDQKETSTKFQVTISKSA XP_004839295.1/1-1004 PLMREGSATAASKKPLASSQSAPVLTAFSLSHAEEDHTLVKEEDQKESGTKFQVTISRSA . :: .* * .*. ***: .***** . *.* . :****:* .**.*****:** ENSP00000368876/1-1019 REKMQLKQMKEMELLRRLEEPRTGQELTSQCLGSQRAFMKEGLLPLRGSGTLSVPTRLSG ENSMUSP00000114359/1-1022 QEKMRLKQMKEMELLRRAKEPEWERELVSQGLGTRRTSAKEGLLPLRGSGALSEPAGMSS ENSRNOP00000038699/1-998 QEKMRLKQLKEMELLRRAKEPERERELASQGLGTWRTSAKEGLLPLRGSGTLSEPTGMSS ENSCPOP00000004219/1-1020 QEKMRLKQMKEMELFRRVKEPEREWEPASQGLGSRRALVKEGLLPLRGSGTLSVPTGQSS XP_004839295.1/1-1004 QEKMRLKQMKEMESLQRAKEPEREWALAPQGLGSRRTFVKEGLLPLRGSGTQSMPSRLSS :***:***:**** ::* :**. ..* **: *: ***********: * *: *. ENSP00000368876/1-1019 PCRNDVSIILRKWASRASLPSIPISRQEPRFARHASANSLPAVLTLGSPEW--EEEEEMD ENSMUSP00000114359/1-1022 PRRNNMGALQRKRANRASLPSIPVSKQEPGFARHASANSLPAVLTLGSPEW-EEEEEEMD ENSRNOP00000038699/1-998 PRRNNIGVLQRKRANRASLPNIPVSKQEPGFARHASANSLPAMLTLGSPEWEEEEEEEMD ENSCPOP00000004219/1-1020 PCRNS-STLLRKRANRSSLPSIPVSKQEPSFARHASANSLPAVLSLGSPDW-KEEEEEMD XP_004839295.1/1-1004 PCRNSSGIPLRKRANRSSLPSIPVGKQEPSFARHASANSLPAVLTLGSPEW-EAEEEEMD * **. . ** *.*:***.**:.:*** ************:*:****:* ****** ENSP00000368876/1-1019 LRACKELRPFSNPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVLTGKLHDVCLV ENSMUSP00000114359/1-1022 LRALRELRPFSNPELGLTDALQCLNSNDWQMKEKGLVNIQRLAACHSEVLGTRLHDVSLA ENSRNOP00000038699/1-998 LQALREFRPFSNPELGLTEALQCLSSNDWQMKEKGLVNIQRLAACHSEVLGTRLHDVSLA ENSCPOP00000004219/1-1020 LRILKELRPFSNPELGLTDALQGLSSTDWQMKEKGLVSVQRLAACHPEVLTGRLHDVSLA XP_004839295.1/1-1004 LRTFKELRPFSNPELGLMDALQGLSSSDWQVKQKSLVSIQRLAACHPEVLAGRLHDVSVA *: :*:********** :*** *.*.***:*:*.**.:*******.*** :****.:. ENSP00000368876/1-1019 VTGEVTNLRSKVSHLAISTLGDLFQALKKNMDQEAEEIARCLLQKMADTNEFIQRAAGQS ENSMUSP00000114359/1-1022 VTAEVTNLRSKVSRLAISTLGDLFRVLKKNMDQEAEEIVRCLLQKMGNTSEFIQRAANRA ENSRNOP00000038699/1-998 VTAEVTNLRSKVSRLAISTLGDLFRALKKSMDQEAEEIVRCLLQKMGNTSEFIQRAANRA ENSCPOP00000004219/1-1020 VTGEVTNLRSKVSRLAIRTLGDLFRALKKNMDQEAEAVTRCLLQKIGNTSEFIQRAASRA XP_004839295.1/1-1004 VTGEVTNLRSKVSRLAISTLGDLFRALKKNMDQEAEGVTRCLLQKMGNASEFIQRAASRA **.**********:*** ******:.***.****** :.******:.::.*******.:: ENSP00000368876/1-1019 LRAMVENVTLARSLVVLTSAGVYHRNPLIRKYAAEHLSAVLEQIGAEKLLSGTRDSTDML ENSMUSP00000114359/1-1022 LGAMVENVTPARALVALTSAGVYHRNPLVRKCTAKHLSAVLEQIGAEKLLSGSRDNTDML ENSRNOP00000038699/1-998 LGAMVENVTPARALVALTSAGVYHRNPLVRKCTAKHLSAVLEQIGAEKLLSGSRDNTDML ENSCPOP00000004219/1-1020 LGAMVESVSPARALTALTVAGVYHRNPLVRKCTAEHLSAVLEQMGAEKLLSGSRDSIDAL XP_004839295.1/1-1004 LGAMVETVTPARALTALTSAGVYHRNPLVRKCTAEHLSAVLEQIGAEKLLSGSRDSIDML * ****.*: **:*..** *********:** :*:********:********:**. * * ENSP00000368876/1-1019 VHNLVRLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKVMAAIKQQGIEDN ENSMUSP00000114359/1-1022 VHNLVRLAQDSNQDTRFYGRKMVNILMANAKFDAFLKQSLPSHDLRKVMAAIKQRGIQDN ENSRNOP00000038699/1-998 VHNLVRLAQDSNQDTRFYGRKMVNILMANAKFDAFLKQSLPSHDLRKVMAAIKQRGIQDN ENSCPOP00000004219/1-1020 VHTLVRLAQDSNQDTRFYGRKMVTILMANPKFDTFLKQSRPSHDLRKVMAAIKQRGLEEN XP_004839295.1/1-1004 VHTLVRLAQDSNQDTRFYGRKMVTILMANAKFDVFLKQSLPSHDLRKVMAAIKQRGLEDN **.********************.*****.***.***** **:**:********:*:::* ENSP00000368876/1-1019 DELPSAKGRKVLRSLVVCENGLPIKEGLSCNGPRLVGLR-STLQGRGEMVEQLRELTRLL ENSMUSP00000114359/1-1022 HELQSAKGRKVSKSLVVCENGLPSHEGLGSNGPRLMGLRSSSVRGSVETSEQLRELTRLL ENSRNOP00000038699/1-998 HELPSAKGRKVLKSLVVCENGLPSQEGV-------------------EMAEQLRELTRLL ENSCPOP00000004219/1-1020 HEFPSAKGRKVSRSLVACENGLPTEEGLGSSGLRL-AMH-SSLRGGMEIAERLRELTRLL XP_004839295.1/1-1004 HELPSAKGRKVSRSLVACENGLLIEEGVGSNGPWL-AVR-SSLPGGVEIAEQLRELRRLL .*: ******* :***.***** .**: * *:**** *** ENSP00000368876/1-1019 EAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDSNKKVNQWALESFAKMI ENSMUSP00000114359/1-1022 EAKEFQARMEGVGKLLEYCKAKPELVAANLVQVFDVFTPRLHDSNKKVNQWALESLAQML ENSRNOP00000038699/1-998 EAKEFQARMEGVGKLLEYCKTKPEHVAANLVQVFDAFTPRLHDSNKKVNQWALESLAQML ENSCPOP00000004219/1-1020 EAKEYQSRMEGVGRLLEHCETKPELIMANLVQVFDAFTPRLQDSNKKVNQWALESLAKMI XP_004839295.1/1-1004 EAREYQSRMEGVARLLEHCKTKPELIIANLVQVFDAFTPRLQDSNKKVNQWALESLAKMI **:::::*****.:*** *::*.* : *:******.*****:*************:*:*: ENSP00000368876/1-1019 PLLRESLHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAMVESLDNLCLLPALAGRVRFL ENSMUSP00000114359/1-1022 PILKESIHPMLLSLIIAAADNLNSKNSGISTAASTVLDAMMGSLDHLCLLQAFAGRVRFL ENSRNOP00000038699/1-998 PILRESIHPMLLSLIIVAADNLNSKNSGISTAASTVLDAMMDSLDHLCLLQAFAGRVRFL ENSCPOP00000004219/1-1020 PLLKDSVHPMLLSLITAVADNLNSKNSGIATAAVTVLDAMIESLDHICLLQAFAGRVRFL XP_004839295.1/1-1004 PLLKDSVHPMLLSLIIAVADNLNSKNLGITTAATSVLDAMTESLDHLVLLQAFAGRVRFL *:*::*:******:* ..******** ** :** :***** ***:: ** *:******* ENSP00000368876/1-1019 SGRAVLDVTDRLAVLVASVYPRKPQAVERHVLPILWHFLNTATRNGTLPGPSGNIRGVVC ENSMUSP00000114359/1-1022 TGPAVLDITDRLSVLVASVYPRKPQAVERHILPVLWYFLNKMSGNGVLPGRGGNVRTAVC ENSRNOP00000038699/1-998 TGPAVLDVTDRLSALVASVYPRKPQAVERHILPVLWYFLNKMTGNGVLPGRGGNVRTAVC ENSCPOP00000004219/1-1020 SGCAVLDITGRLSVLVASVYPRKPQAVERHVLPVLWYLLNNMTGGGILPGRSANVRTVVI XP_004839295.1/1-1004 SGRAVLDITERLSVLVASVYPQKPQAVERHVLPVLWYFLNNMIRSGTLPGLGGNVRTVVC :* ****:* **:.*******:********:**:**::**. .* *** ..*:* .* ENSP00000368876/1-1019 RLSRSLQEHMGSRLLDFAASQPKHVLKTLQELLDSESLGGSRKATDRGVAPDSKTTGSSY ENSMUSP00000114359/1-1022 RLARSLQEQMGSRLQDFAASQPQQVLKALQGLLASESLGANDKVIGGRMAPDIQMTGTTC ENSRNOP00000038699/1-998 RLARSLQEQMGSRLQDFAANQPQQALKTLQGLLVSESLGDNNKVTSGGMAPDIQMTGAIC ENSCPOP00000004219/1-1020 QLSKTLQQQMGTRLQDFAAGQPKQVLKMLQELLNTESPGGSCKVSDRGTLPDSRTAGSAC XP_004839295.1/1-1004 QLSRTLQQQMGTRLQDFATAQPKQVLRMLQE-LNTESPGGPHEVTERGAT---------- :*:::**::**:** ***: **::.*: ** * :** * :. ENSP00000368876/1-1019 PFQLD ENSMUSP00000114359/1-1022 PQQLD ENSRNOP00000038699/1-998 PQQLD ENSCPOP00000004219/1-1020 SLQVD XP_004839295.1/1-1004 -----