CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000130668/1-848 -----------------------------------------------------------M ENSRNOP00000048442/1-847 ------------------------------------------------------------ ENSP00000474028/1-907 ARERSSAAAGRKQFCKNNHTQPGNCLPLGLSLSRRPHSLQGGGHRIYRGKTSLPASRLQC ENSCPOP00000004213/1-845 -----------------------------------------------------------S XP_004856656.1/1-847 -----------------------------------------------------------M ENSMUSP00000130668/1-848 LRTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK ENSRNOP00000048442/1-847 ----------FFFSFAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK ENSP00000474028/1-907 CQTKDFIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK ENSCPOP00000004213/1-845 SQTFECIFEL--DSFSVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEK XP_004856656.1/1-847 LQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPSGEK . :****************************************.*** ENSMUSP00000130668/1-848 LSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFK ENSRNOP00000048442/1-847 LSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTAEDGTQSEATVNVKIFQKLMFK ENSP00000474028/1-907 LTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFK ENSCPOP00000004213/1-845 LSPNQQRISVVWNDDSSSTLTIYNADIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFK XP_004856656.1/1-847 LSPNQQRISVVWNDDSSSTLTIYNADIDDAGIYKCVVSGEDGSESEATVNVKIFQKLMFK *:*************.*********:***********:.***::**************** ENSMUSP00000130668/1-848 NAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK ENSRNOP00000048442/1-847 NAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK ENSP00000474028/1-907 NAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK ENSCPOP00000004213/1-845 NAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK XP_004856656.1/1-847 NAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKK ********:*************************************************** ENSMUSP00000130668/1-848 TDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFP ENSRNOP00000048442/1-847 TDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFP ENSP00000474028/1-907 TDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFP ENSCPOP00000004213/1-845 TDEGTYRCEGRILARGEINFKDIQVVVNVPPTVQARQSIVNATANLGQSVTLVCDAEGFP XP_004856656.1/1-847 TDEGTYRCEGRILARGEINFKDIQVVVNVPPTVQARQSIVNATANLGQSVTLVCDAEGFP *************************:******:****.******************:*** ENSMUSP00000130668/1-848 EPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASI ENSRNOP00000048442/1-847 EPTMSWTKDGEPIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASI ENSP00000474028/1-907 EPTMSWTKDGEQIEQ-EEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATI ENSCPOP00000004213/1-845 EPTMSWTKDGEPIEN-EEDDEKYIFSDDSSELTIRKVDKNDEAEYVCIAENKAGEQDASI XP_004856656.1/1-847 EPTMSWTKDGEPIEN-EEDDEKYIFSDDSSELTIRKVDKNDEAEYVCIAENKAGEQDASI *********** **: ******:*******:***::*********:************:* ENSMUSP00000130668/1-848 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK------- ENSRNOP00000048442/1-847 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPE ENSP00000474028/1-907 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK------- ENSCPOP00000004213/1-845 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTATRNISSEEK------- XP_004856656.1/1-847 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEK------- *******************************************:********* ENSMUSP00000130668/1-848 ---TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG ENSRNOP00000048442/1-847 KQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG ENSP00000474028/1-907 ---TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG ENSCPOP00000004213/1-845 ---TLDGHMVVRSHARVSSLTLKSIQYTDAGEYLCTASNTIGQDSQSMYLEVQYAPKLQG XP_004856656.1/1-847 ---TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG ******************************:************************** ENSMUSP00000130668/1-848 PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS ENSRNOP00000048442/1-847 PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS ENSP00000474028/1-907 PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS ENSCPOP00000004213/1-845 PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTHSASYLEVTPDS XP_004856656.1/1-847 PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTHSASYLEVTPDS ************************************************ *********** ENSMUSP00000130668/1-848 ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPI ENSRNOP00000048442/1-847 ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPI ENSP00000474028/1-907 ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPI ENSCPOP00000004213/1-845 ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPI XP_004856656.1/1-847 ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPI ************************************:*********************** ENSMUSP00000130668/1-848 LKYKAEWKSLGEESWHFKWYDAKEANMEGIVTIMGLKPETRYSVRLAALNGKGLGEISAA ENSRNOP00000048442/1-847 LKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAA ENSP00000474028/1-907 LKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAA ENSCPOP00000004213/1-845 LKYKAEWRALGEEVWHSKWYDAKEANMEGIVTIMGLKPETTYAVRLAALNGKGLGEISAA XP_004856656.1/1-847 LKYKAEWRALGEEVWHSKWYDAKEANMEGIVTIMGLKPETTYAVRLAALNGKGLGEISAA *******:::*** ** ********.*******:****** *:***************** ENSMUSP00000130668/1-848 TEFKTQPVR-EPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEI ENSRNOP00000048442/1-847 TEFKTQPVR-EPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEI ENSP00000474028/1-907 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEI ENSCPOP00000004213/1-845 SEFKTQPVR-EPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALSSDWKPEI XP_004856656.1/1-847 SEFKTQPVR-EPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALSSDWKPEI :*******: *************************************:****:*:***** ENSMUSP00000130668/1-848 RLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLS ENSRNOP00000048442/1-847 RLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLS ENSP00000474028/1-907 RLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLS ENSCPOP00000004213/1-845 RLPSGSDHVMLKSLEWNAEYEVSVVAENQQGKSKPAHFVFKTSAQPTAIPANGSPTSGLS XP_004856656.1/1-847 RLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKPAHFVFKTSAQPTAIPANGSPTAGLS **************:******* ***********.*****:***************:*** ENSMUSP00000130668/1-848 TGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFS ENSRNOP00000048442/1-847 TGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFS ENSP00000474028/1-907 TGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFS ENSCPOP00000004213/1-845 TGAIVGILIVIFVLLLVVVDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFS XP_004856656.1/1-847 TGAIVGILIVIFVLLLVVVDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFS ******************:************:**************************** ENSMUSP00000130668/1-848 KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVETKSEPPESEAKPAPTE ENSRNOP00000048442/1-847 KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVETKSEPQESEAKPAPTE ENSP00000474028/1-907 KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAE ENSCPOP00000004213/1-845 KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKSESQESETKPVPAE XP_004856656.1/1-847 KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKLECQESETKPAPAE ********************************************:* * *:*:**.*:* ENSMUSP00000130668/1-848 VKTVPNDATQTKENESKA ENSRNOP00000048442/1-847 VKTVPNEATQTKENESKA ENSP00000474028/1-907 VKTVPNDATQTKENESKA ENSCPOP00000004213/1-845 VKTVPNDATQTTENESKA XP_004856656.1/1-847 VKTVPNDATQTKENESKA ******:****.******