CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000041308/1-970 MSSVSEERRKRQHSIKEGLQFIQPPLSYPGTQEQYAVYLHALVRNLFNEGNDIYRECDWR ENSRNOP00000003309/1-706 MSSVSEERRKRQHSIKDGLQFIQSPLSYPGTQEQYAVYLHALVRNLFNEGNDVYRECDWS ENSCPOP00000004019/1-974 MSSVTEERRKRQQNIKEGLQFIQSSLSYLGTQEQYAVYLQALVRNLFNEGNDFYRERDWN ENSP00000379773/1-971 MSNVSEERRKRQQNIKEGLQFIQSPLSYPGTQEQYAVYLRALVRNLFNEGNDVYREHDWN XP_004855925.1/1-970 MSSVSEERRKRQQNIKEGLQFIQSPLSYPGTQEQYAVYLRALVRNLFNEGNDVYREHDWN **.*:*******:.**:******..*** **********:************.*** ** ENSMUSP00000041308/1-970 GSLIQYSEALSIANYAKSEEILIPTEIIEKLRINRIACYSNMGLRDEVLEDCNAVLSVNA ENSRNOP00000003309/1-706 GSLLQYSEALNIASYAKSEEILIPKEIIEKLQINRIACYSNMGLHDKVLEDCNAVLSVNA ENSCPOP00000004019/1-974 SSISQYTEALRIADYAESDKISIPKEIIEKLHVNRMACYSNMGLHDKVLEDCNIVLSLND ENSP00000379773/1-971 NSISQYTEALNIADYAKSEEILIPKEIIEKLYINRIACYSNMGFHDKVLEDCNIVLSLNA XP_004855925.1/1-970 SSISQYTEALNIADYAKSEEILIPKEIIEKLHINRMACYSNMGFHDKVLEDCNTILSLNA .*: **:*** **.**:*::* **.****** :**:*******::*:****** :**:* ENSMUSP00000041308/1-970 SNCKALYRKAKALSDLGHYREAYDAVAKCSLAVP-QDEHVIKLTQELAQKLGFKIRKAYV ENSRNOP00000003309/1-706 SNCKALYRKAKALSDLRRYREAYDVVAKCSLAVP-QDEHVIKLTQELAQKLGFKIRKAYV ENSCPOP00000004019/1-974 SNCKALYRKSKALSDLGSYGEAYLTVAKCSLAMPQQDEHVIKLTQALAQQLGLKIRKAYV ENSP00000379773/1-971 SNCKALYRKSKALSDLGRYKKAYDAVAKCSLAVP-QDEHVIKLTQELAQKLGFKIRKAYV XP_004855925.1/1-970 SNCKALYRKSKALSDLGRYREAYDAVAKCSLAVP-QDEHVIKLTQELAQKLGFKIRKAYV *********:****** * :** .*******:* ********** ***:**:******* ENSMUSP00000041308/1-970 RAEHLLKAVPGDGAPKAVNYSVEDIEPDLLAPRQEALSVASLPTSSFSHVIGSELASVPI ENSRNOP00000003309/1-706 RAELSLKAVPGDGAPKAVNHSVEDIEP--------------------------------- ENSCPOP00000004019/1-974 RAEHSLKSVPGDGTAKVVDYSVEDIEPDLFTPRQETLPVISLPLSSFSHDVRSELASVPT ENSP00000379773/1-971 RAELSLKSVPGDGATKALNHSVEDIEPDLLTPRQEAVPVVSLPAPSFSHEVGSELASVPV XP_004855925.1/1-970 RAEHSLKSVPGDGTTKAVNYSVEDIEPDLLVPRQEAPPVASSPASSFPHDVGGQLATVPA *** **:*****:.*.:::******* ENSMUSP00000041308/1-970 MPVTSVLQLQVDESPLPSTVFANGGKIPFTISDAFLDD-DIVLGDEIDALLDSAPETNDA ENSRNOP00000003309/1-706 -------------------VFANGGKIPFTISEAFLDD-DIVLGDEIDALLDSAPETNDA ENSCPOP00000004019/1-974 VPLPSILPLQVEESTLSSTVLANGGKIPFTMPEAFPDDGDMVLGDEIDDLLDSAPETNDT ENSP00000379773/1-971 MPLTSILPLQVEESALPSAVLANGGKMPFTMPEAFLDDGDMVLGDELDDLLDSAPETNET XP_004855925.1/1-970 VPLPSVLPLQVEESALPSTVLANGGKMPFTMPEAFLDDGDMVLGDEIDDLLDSAPETNDT *:*****:***:.:** ** *:*****:* *********:: ENSMUSP00000041308/1-970 VMSSTLVRGPLPTASAAPSLPFRTQSLLGTLPMGTRY-PEPSFADFFPPLTSSLEEFYSS ENSRNOP00000003309/1-706 VMSSTLVRGPLPTASAAPGFPFRAPSLLGTLPIGARYAPEPSFAECFPPLTSPLEDFYSS ENSCPOP00000004019/1-974 VMPPALVQVPLPTSSVAPSLPFSA-SLLGTLPIGARYAPPSSFAELYPPLTSSLEDFCSS ENSP00000379773/1-971 VMPSALVRGPLQTASVSPSMPFSA-SLLGTLPIGARYAPPPSFSEFYPPLTSSLEDFCSS XP_004855925.1/1-970 VMPSALVRGPLPTSSVAPGLPFSA-SLLGTLPIGARYAPPPSFAELYPPLTSSLEDFCSS **..:**: ** *:*.:*.:** : *******:*:** * .**:: :*****.**:* ** ENSMUSP00000041308/1-970 LNSFSVTESKRDLCTSTAREGTPLNNSNSSLLLMNGPGNLLASENFLGITSQPRNDF--G ENSRNOP00000003309/1-706 LNAFSVTESTRDLSTSTAREGTALNSSNSSLLLMNGPGSLFASDNFLGITSQPSNDC--G ENSCPOP00000004019/1-974 LNSFSVSEPKRDLSTSTSREGTTLNNSNSSLSLMNRPSSLFTFDGSLGISNQPRNDFDFG ENSP00000379773/1-971 LNSFSMSESKRDLSTSTSREGTPLNNSNSSLLLMNGPGSLFASENFLGISSQPRNDF--G XP_004855925.1/1-970 LNSFSMSEPKRDLSTSTSREGTTLNNSNSSLLLMNGPSSLFTSDGFLGISSQPRNDF--G **:**::*..***.***:****.**.***** *** *..*:: :. ***:.** ** * ENSMUSP00000041308/1-970 NFFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANVDHKCKKDILI ENSRNOP00000003309/1-706 NLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILI ENSCPOP00000004019/1-974 KFFGSAITKPSSSVTPRHPLEGTHELRPACQFCFVKSGPKLMDFTYHANIDHKCKKDILI ENSP00000379773/1-971 NFFGSAVTKPSSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANIDHKCKKDILI XP_004855925.1/1-970 NFFGSAVTKPSSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYQANVDHKCKKDILI ::***.::** ** ************* ***:**************:**:********** ENSMUSP00000041308/1-970 GRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYPGHCTFAYCQEEIDVWTLE ENSRNOP00000003309/1-706 GRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYSGHCTFAYCQEEIDVWTLE ENSCPOP00000004019/1-974 GRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECKYSGHCTFAYCQEEIDVWTLE ENSP00000379773/1-971 GRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLE XP_004855925.1/1-970 GRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLE ***********************************::**:*.****************** ENSMUSP00000041308/1-970 RKGAFSREAFFGGNGKINLTVVRILQEHHGEFTFLCEKCFDHKPRMISKRNKDNSTACSH ENSRNOP00000003309/1-706 RTGAFSREAFFGGNGKISLTVVKILQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSH ENSCPOP00000004019/1-974 RKGAFSREAFFGGNGKINLTVLKLLQEHVGEFIFLCERCFDHKPRMISKQNKD-STACSH ENSP00000379773/1-971 RKGAFSREAFFGGNGKINLTVFKLLQEHLGEFIFLCEKCFDHKPRMISKRNKDNSTACSH XP_004855925.1/1-970 RKGAFSREAFFGGNGTINLTVFKLLQEHLGEFIFLCERCFDHKPRMISKRNKD-STACSH *.*************.*.***.::**** *** ****:***********:*** ****** ENSMUSP00000041308/1-970 PVTKHEFEDNKCLVHILRETTVKYSKIRSFHKQCQFDICRHEVRYGCVREDECFYAHSLI ENSRNOP00000003309/1-706 PVTKHEFEDNKCLVHILREATVKYSKIRSFHKQCQLDLCRHEVRYGCVREDECFYAHSLI ENSCPOP00000004019/1-974 PVTKHEFEENKCLVHILRETSVKYSKIRPFHSQCQLDLCRHEVRYGCSREDECFYAHSLV ENSP00000379773/1-971 PVTKHEFEDNKCLVHILRETTVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLV XP_004855925.1/1-970 PVTKHEFEDNKCLVHILRETSVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLV ********:**********::*******.** ***:*:********* ***********: ENSMUSP00000041308/1-970 ELKVWIMQSERGISHDDIAQQSKQYWRSLQASMPGVQVLGNQIMPGLLNMEIKFVCAQCL ENSRNOP00000003309/1-706 ELKVWIMQNERGISHDDIAQQSRQYWRSLEASLPGLQVLGNQIMPGLLNMEIKFVCAQCL ENSCPOP00000004019/1-974 ELKVWIMQSDTGILHDDIAQESKQYWQNLEANVPGTQVLGNLIMPGSLNMKIKFVCAQCL ENSP00000379773/1-971 ELKVWIMQNETGISHDAIAQESKRYWQNLEANVPGAQVLGNQIMPGFLNMKIKFVCAQCL XP_004855925.1/1-970 ELKVWIMQNETGISHDAIAQESKRYWQNLEANVPGAQVLGNQIMPGFLNMKIKFVCAQCL ********.: ** ** ***:*::**:.*:*.:** ***** **** ***:********* ENSMUSP00000041308/1-970 RNGQVIEPDRNRKYCSA-KAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLC ENSRNOP00000003309/1-706 RNGQVTEPDRNRKYCSA-KAQHSWTKERRAMRAMSFE----------------PMQ---- ENSCPOP00000004019/1-974 RNGQVVEPDQNRKYCSAKKEKHLWTKDRRAMRVMSLERMKWMNIRPLPTKKQMPLQFDMC ENSP00000379773/1-971 RNGQVIEPDKNRKYCSA-KARHSWTKDRRAMRVMSIERKKWMNIRPLPTKKQMPLQFDLC XP_004855925.1/1-970 KNGQVIEPDQNRKYCSA-KARHSWTKDRRAMRVMSLERMKWMNIRPLPTKKQMPLQFDLC :**** ***:******* * :* ***:*****.**:* *:* ENSMUSP00000041308/1-970 NHIANRKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETASH ENSRNOP00000003309/1-706 ------------------------------------------------------------ ENSCPOP00000004019/1-974 NHISAGKKCQYVGNCSFAHSHEEREVWTYMKDNGIQDMEQFYELWLKSQKNGKSDDVASQ ENSP00000379773/1-971 NHIASGKKCQYVGNCSFAHSPEEREVWTYMKENGIQDMEQFYELWLKSQKNEKSEDIASQ XP_004855925.1/1-970 NHIASGKKCQYVGNCSFAHSPEEREVWTYMKDNGIQDMEQFYELWLKSQKNEKSDDIASQ ENSMUSP00000041308/1-970 CSKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCW ENSRNOP00000003309/1-706 --------------------------------------------------------PYC- ENSCPOP00000004019/1-974 ANKENGKQIHMPTDYAEVTADFHCWMCGKNCNSEKQWQGHISSEKHKEKFFHTEDDQYCW ENSP00000379773/1-971 SNKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCW XP_004855925.1/1-970 SNKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCW ** ENSMUSP00000041308/1-970 QHRFPTGYFSICERYINGSCTEGSSCKFAHGNAELHEWEERRKALQMKFKKARKDHLIAP ENSRNOP00000003309/1-706 ------------------------------------------------------------ ENSCPOP00000004019/1-974 QHRFPTGYFSICERYMNAICTEGNSCKFAHGNAELQEWEERRNALKMKLSKARKDHLIAP ENSP00000379773/1-971 QHRFPTGYFSICDRYMNGTCPEGNSCKFAHGNAELHEWEERRDALKMKLNKARKDHLIGP XP_004855925.1/1-970 QHRFPTGYFSICERYMNGTCIEGSSCKFAHGNAELHEWEERRNALKMKLSKARKDHLIAP ENSMUSP00000041308/1-970 NDNDFGKYSFLFKDLK ENSRNOP00000003309/1-706 ---------------- ENSCPOP00000004019/1-974 NDNDFGKYSFLFKDLN ENSP00000379773/1-971 NDNDFGKYSFLFKDLN XP_004855925.1/1-970 NDNDFGKYSFLFKDLN