CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000003990/1-448 MIMTDSREVTDLDPPVETSQEQEDLLIVKVEEEDCTWMQEYNPPPFETFYQRFKHFQYHE ENSMUSP00000082814/1-819 MIMTESRAVIHLEPPAETSQEQADLLIVKVEEEDCSWMQGYNRPVLETFYQRFKHFQYHE ENSRNOP00000001300/1-822 --MTESRAVVHLEPPAETSQEQADLLIVKVEEEDCSWMQGYNRPVLETFYQRFKHFQYHE ENSP00000322872/1-839 MIMTESREVIDLDPPAETSQEQEDLFIVKVEEEDCTWMQEYNPPTFETFYQRFRHFQYHE XP_004840581.1/1-703 MIMTDSREVTDLDPPVEPSQEQEDLLIVKVEEEDCTWMQEYNPPTFETFYQRFKHFQYHE **:** * .*:**.*.**** **:*********:*** ** * :*******:****** ENSCPOP00000003990/1-448 ASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQAWVREHHPESGEE ENSMUSP00000082814/1-819 AAGPRDALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQAWVREHHPESGEE ENSRNOP00000001300/1-822 ATGPRDALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQAWVREHHPESGEE ENSP00000322872/1-839 ASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQPWVREHHPESGEE XP_004840581.1/1-703 ASGPREALSQLRVLCCEWLRPELHTKEQILELLVLQQFLSILPEEFRAWVREHHPESGEE *:***:*****************************:***:******:.************ ENSCPOP00000003990/1-448 AVAVIESIQRELEEHRQQVSGRGDRSIEGELIHCVLKPEEGGKKIAALSAYKHKSLVLEG ENSMUSP00000082814/1-819 AVAVIESIQRELEERRQQIATSPE----------VL-PQKMVPPGATQESFSHQCLPVEA ENSRNOP00000001300/1-822 AVAVIESIQRELEERRQQIVTCPE----------VL-PQKMVPPGATQESSSHQFLPVEA ENSP00000322872/1-839 AVAVIENIQRELEERRQQIVACPD----------VL-PRKMATPGAVQESCSPHPLTVDT XP_004840581.1/1-703 AVAVIENMQRELEEPRQQIVACPE----------VL-PQKMVSPGAVQETFGHQFLSMDA ******.:****** ***: : ** *.: *. .: : * :: ENSCPOP00000003990/1-448 KRER----------SALPVLQAPSLPLEDSQELTASLLSAGSQKLVEMEDVADVAVSFIL ENSMUSP00000082814/1-819 QPERESQN--LLEENALPVLQVSSVPLKDSQELTDSLLSDGPQKLVKTEDVADVAVSFIL ENSRNOP00000001300/1-822 QSDQEPQN--LLEENALPVLQVPSVPLKDSQEPTASLLSAGPQKLVKIEDVADVAVSFIL ENSP00000322872/1-839 QPEQAPQKPRLLEENALPVLQVPSLPLKDSQELTASLLSTGSQKLVKIEEVADVAVSFIL XP_004840581.1/1-703 QPEQEPRKPHVLEEN--------------------------------------------- : :: . ENSCPOP00000003990/1-448 EEWGHVDQSQKSVYRDGRKENYGSIASLDCESKDNNVDLIVKQISNEASSPHSHWVAAGS ENSMUSP00000082814/1-819 EEWAHLDQSQKSLGRDSRKEDCESTTPVDYEPKEGNLEFTVQQVSDAA---DPHWVAAER ENSRNOP00000001300/1-822 EEWGHLDQSQKSLSRDGRKEDCERTTPVDYEPKEGNLELVVQQVSDAV---DPHWVAAES ENSP00000322872/1-839 EEWGHLDQSQKSLYRDDRKENYGSITSMGYESRD-NMELIVKQISDDS---ESHWVAPEH XP_004840581.1/1-703 ----------------------------DYESKDNNMELTAKQISNEASSPNSHWVAVGS . *.:: *::: .:*:*: ..**** ENSCPOP00000003990/1-448 TQKDIPQSQGFAEVSDLKGMIQRWQVNPTVGKPRQNPS---------------------- ENSMUSP00000082814/1-819 TEKNGVQRPESGEVSDLKDMVPRWQVNPTSG----NPRQKRPLRSGPDVNRKQKSNGERG ENSRNOP00000001300/1-822 TEQNSVQPQESAEVSDLKDTVQRWQVNPTWR----NPRPKRSLSSGLDVNRKQKSNGERG ENSP00000322872/1-839 TERSVPQDPDFAEVSDLKGMVQRWQVNPTVGKSRQNPSQKRDLDAITDISPKQSTHGERG XP_004840581.1/1-703 TERNISQSQEFAEVSDFKGMVQRWQVNPTMGKLKQNPSQKRDLSTSKDTNRKQSTNGERG *::. * .****:*. : ******* ** ENSCPOP00000003990/1-448 ------------------------------------------------------------ ENSMUSP00000082814/1-819 HRCGDCGKFFLQASNFIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHTGEKPYKCQ ENSRNOP00000001300/1-822 HRCGDCGKFFLQASNFIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHTGEKPYKCQ ENSP00000322872/1-839 HRCSDCGKFFLQASNFIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHTGEKPYKCQ XP_004840581.1/1-703 HRCNDCGKFFLQASNFIQHRRIHTGEKPFQCGECGKSYNQRVHLTQHQRVHTG------- ENSCPOP00000003990/1-448 ------------------------------------------------------------ ENSMUSP00000082814/1-819 VCGKAFRVSSHLVQHHSVHSGERPYGCNECGKSFGRHSHLIEHLKRHFREKSQRCSDRRS ENSRNOP00000001300/1-822 VCGKAFRVSSHLVQHHSVHSGERPYGCSECGKSFGRHSHLIEHLKRHFREKSQRCSDRRS ENSP00000322872/1-839 VCGKAFRVSSHLVQHHSVHSGERPYGCNECGKNFGRHSHLIEHLKRHFREKSQRCSDKRS XP_004840581.1/1-703 -------------------------------------------------------SDRRS ENSCPOP00000003990/1-448 ------------------------------------------------------------ ENSMUSP00000082814/1-819 KNTKLNIK-QIPGLSEADLELSGEVQRNACQAEGHSEGCEHQ---DGQQGVVMKETLGQS ENSRNOP00000001300/1-822 KDTKLNVQ-QIPGLSEADVEPSGEVQRNACEAEGHSEGCEYQDGAGGQEGVIMKETLGQS ENSP00000322872/1-839 KNTKLSVKKKISEYSEADMELSGKTQRNVSQVQDFGEGCEFQGKLDRKQGIPMKEILGQP XP_004840581.1/1-703 RNTKLNVKNKISEFSEADMEVPEKIQRNASEVQGFQEGYEHQGKADRKQGLPMKEILGQP ENSCPOP00000003990/1-448 ------------------------------------------------------------ ENSMUSP00000082814/1-819 SSKRTDCNEFSYVHKKSSPGERPHQCNECGKSFIQSAHLIQHRRIHTGEKPFRCEECGKS ENSRNOP00000001300/1-822 SSKRTDCNELSYVHKKPSPGERPHKCNECGKSFIQSAHLVQHRRIHTGEKPFRCEECGKS ENSP00000322872/1-839 SSKRMNYSEVPYVHKKSSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRCEECGKS XP_004840581.1/1-703 SSKRINCSEVTYIHKKPSTGERPHKCNECGKSFIQSAHLVQHQRIHTGEKPFRCDECGKS ENSCPOP00000003990/1-448 ------------------------------LSSHLVQHHSVHSGERPYGCKECGKRFGRQ ENSMUSP00000082814/1-819 YNQRVHLTQHHRVHTGEKPYACHLCGKAFRVRSHLVQHQSVHSRERPFKCNECGKGFGRR ENSRNOP00000001300/1-822 YNQRVHLTQHHRVHTGEKPYACHLCGKAFRVRSHLVQHQSVHSRERPFKCNECGKGFGRR ENSP00000322872/1-839 YNQRVHLTQHQRVHTGEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRR XP_004840581.1/1-703 YNQRVHLTQHQRVHTGEKPYTCHLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRR : ******:**** ***: *:**** ***: ENSCPOP00000003990/1-448 SHLIEHLKRHFREKSQRCTWRAIALHMNVSLLIKFLLHVGQKNEKNSICEEAYSWNLAVI ENSMUSP00000082814/1-819 SHLAGHLRLHSRDKSHQCHECGEIFFQYVSLLEHQVLHVGQKSEKNGICEEAYSWNLTVI ENSRNOP00000001300/1-822 SHLAGHLRLHSRDKSHQCHECGEIFFRYVSLLEHQMLHVGQKSGNNSVCEEAHSWNLTVM ENSP00000322872/1-839 SHLAGHLRLHSREKSHQCRECGEIFFQYVSLIEHQVLHMGQKNEKNGICEEAYSWNLTVI XP_004840581.1/1-703 SHLAGHLRLHSREKSHQCHECGEIFFQYVSLIEHQVLHVGQKNEKNGICEEAYSWNLTVI *** **: * *:**::* . :. ***: : :**:***. :*.:****:****:*: ENSCPOP00000003990/1-448 EDKKIELS---------------------------------------------------- ENSMUSP00000082814/1-819 KDKKLELQ--EQPYQCDSCGKAFSYSSDLIQHYRTHSAEKPQKCDACRDSTCQCPHIKQQ ENSRNOP00000001300/1-822 EDKKLELQGEQSPYQCDTCGKAFSYTSDLIQHYRAHSAEKPQKCDACRDSTSQCPHRRQP ENSP00000322872/1-839 EDKKIELQ--EQPYQCDICGKAFGYSSDLIQHYRTHTAEKPYQCDICRENVGQCSHTKQH XP_004840581.1/1-703 EDKKIELQ--EQPYKCDICGRAFNYSSDLIQHYRTHTAEKTHKCDICRGNIGQCSHIKQH :***:**. ENSCPOP00000003990/1-448 -------------------------------LPKERPYSSNECNNNMKHFSNL------- ENSMUSP00000082814/1-819 QKSCPSGKSHQCNECGRGFSLKSHLSQHQRIHTGEKPLQCKECGMSFSWSCSLFKHLRSH ENSRNOP00000001300/1-822 QKICPSGKSHQCSECGRGFGLKSHLSQHQRVHTGEKPFQCKECGMKFSWSCSLLKHLRSH ENSP00000322872/1-839 QKIYSSTKSHQCHECGRGFTLKSHLNQHQRIHTGEKPFQCKECGMNFSWSCSLFKHLRSH XP_004840581.1/1-703 QKICPSAKPHQCNECGRGFTLKSHLSQHQRIHTGEKPFQCKECGMSFSWSCSLFKHLRSH . *:* ..:**. .:. ..* ENSCPOP00000003990/1-448 ---------------- ENSMUSP00000082814/1-819 ERTDP----------- ENSRNOP00000001300/1-822 ERTDP----------- ENSP00000322872/1-839 ERTDPINTLSVEGSLL XP_004840581.1/1-703 ERTDTINTLCA-----