CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000074837/1-1203 MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD ENSRNOP00000039831/1-1203 MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILD ENSP00000385848/1-1205 MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILD ENSCPOP00000003953/1-1070 ------------------------------------------------------------ XP_004851228.1/1-1104 MKVTVCFGGTGIVVPCKQGQLRVRELTQQALARYLKAREKDPGYWVKIHHLEYTDGGILD ENSMUSP00000074837/1-1203 PDDVLADVVEDKDKLIAVFDEQEPLQKTESPGGNPADRQSPDAFETEVAAQLAAFKPVGG ENSRNOP00000039831/1-1203 PDDVLADVVEDKDKLIAVFDEQEPLQKIESPSGNPVDRQSPDAFDTEVAAQLAAFKPIGG ENSP00000385848/1-1205 PDDVLADVVEDKDKLIAVFEEQEPLHKIESPSGNPADRQSPDAFETEVAAQLAAFKPIGG ENSCPOP00000003953/1-1070 -------------QLIAVFEEQEPPCTTESPGGNPAGRQSPDALDTEVAAQLAAFKPVGG XP_004851228.1/1-1104 PDDILADVVEDKDKLIAVFDEQEPLHKIESPSGNPTDRQSPDALETEVAAQLAAFKPIGG :*****:**** . ***.***..******::************:** ENSMUSP00000074837/1-1203 EIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASLSGQSLKPVVLDSTQNVENKEAM ENSRNOP00000039831/1-1203 EIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASPSGQSLKPVVLDSAQNLENRDVM ENSP00000385848/1-1205 EIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKLVVPDSTQNLEDREVL ENSCPOP00000003953/1-1070 EIEVTPSALKLGTPLLVRRSSDPAPGPPADAQPRAAHPGGQSVRPVVSDSTQELGGREVM XP_004851228.1/1-1104 EIEVTPSTLKLGTPLLVRRSSDPAPGPPADAQPRASHLDGQSMRPVVSDSTQNLEDREVM ** ****:***************.*** **:** :: .***:: ** **:*:: .::.: ENSMUSP00000074837/1-1203 NGEQAGLLSLHRPKDELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENS ENSRNOP00000039831/1-1203 NGEQTGLLMLHKTKNELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENS ENSP00000385848/1-1205 NGVQTELLTSPRTKDTLSDMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFIRGIEDNS ENSCPOP00000003953/1-1070 NGVQTELFTAPRTKDALSDMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFIRGIEENS XP_004851228.1/1-1104 NGVQTELLMSPQMKDALSDMTRTVEISGEGSPLGIHVVPFFSSLSGRILGLFIRGIEGNS ** *: *: : *: ******:*******.************************** ** ENSMUSP00000074837/1-1203 RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQNREQYEKSV ENSRNOP00000039831/1-1203 RCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQNREQYEKSV ENSP00000385848/1-1205 RSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQNREQYEKSV ENSCPOP00000003953/1-1070 RCKREGLFQENECIVKINSVELVDKTFAQAQDVFRQAMKSPHVLLQVLSPQNREHYEKSV XP_004851228.1/1-1104 RCKREGLFQENECIVKINNVDLADKTFAQAQDIFRQAMKSTNVLLHVLSPQNREQYEKSV *.*:****:*********.*:* *********:*******. *:*:** *****:***** ENSMUSP00000074837/1-1203 IGPLNIFGNNDGASRTKAAPPARGKPGLKAVHLTRASSPEGEEPASPQQSKSPRVPRLGR ENSRNOP00000039831/1-1203 IGQLNIFGNNDSASRTKAPPPTRGKAGLKAVNPTRANSPEGEESPSPQQSKSPRVPRLGR ENSP00000385848/1-1205 IGSLNIFGNNDGVLKTKVPPPVHGKSGLKTANLTGTDSPETDASASLQQNKSPRVPRLGG ENSCPOP00000003953/1-1070 IGPLHIFGNSDGVLRTKVSPPVHGKSGLKTANLTGANGPEADPATSLQQSKSPRVPRLGR XP_004851228.1/1-1104 IGPLNIFGN-DGILRTKVPPPVHGKLGLKTVNLTGTNSPEAEPSTFLQQSKSPRVPRLGR ** *:**** *. :**..**.:** ***:.: * :..** : .. **.********* ENSMUSP00000074837/1-1203 KPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGA ENSRNOP00000039831/1-1203 KPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGA ENSP00000385848/1-1205 KPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGA ENSCPOP00000003953/1-1070 KPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGA XP_004851228.1/1-1104 KPSSPSLSPLLGFGNKKSAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGA **********:***.:*.****************************************** ENSMUSP00000074837/1-1203 AVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKG ENSRNOP00000039831/1-1203 AVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKG ENSP00000385848/1-1205 AIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEGHFLPRELKG ENSCPOP00000003953/1-1070 AIRDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEGSFLPREL-- XP_004851228.1/1-1104 AIRDGRLQSGDRILEVNGRDVTGKTQEELVAMLRSTKQGETASLVIARQEGSFLPRELKG *::********************:*****************.********* ****** ENSMUSP00000074837/1-1203 EPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFK ENSRNOP00000039831/1-1203 EPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFK ENSP00000385848/1-1205 EPDCCALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFK ENSCPOP00000003953/1-1070 ------------------------------------------------------------ XP_004851228.1/1-1104 EPDCYALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKARETGTDLGIFIKSVIHGGAAFK ENSMUSP00000074837/1-1203 DGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPLEELS ENSRNOP00000039831/1-1203 DGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRLERPLEEIS ENSP00000385848/1-1205 DGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPMEDPA ENSCPOP00000003953/1-1070 DGRLRVNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPTEETA XP_004851228.1/1-1104 DGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPTEETA *****:**********:********************************** *** *: : ENSMUSP00000074837/1-1203 ECGALSRPGFENCQEALSTSRRNDSSILYPFGTYSPQDKRKDLLLPSDGWAENEVPPSPP ENSRNOP00000039831/1-1203 ECGALSRPCFENCQEALSASRRNDSSLLYPCGTYSPQDKRKDLLLPSDGWAENEVPPSPP ENSP00000385848/1-1205 ECGAFSKPCFENCQNAVTTSRRNDNSILHPLGTCSPQDKQKGLLLPNDGWAESEVPPSPT ENSCPOP00000003953/1-1070 ECGAFSKPCFENCQNVLPASSRNESGILHSFDNYSPQDKQKELVLPHDEWARGEAPPSLP XP_004851228.1/1-1104 ECGAFSKPCFENCQNALTTSSRNESGILQSFDNYSPQDKQKDLMLPHDEWAECELLPSLP ****:*:* *****:.:.:* **:..:* . .. *****:* *:** * **. * ** . ENSMUSP00000074837/1-1203 PHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRTVTPVRQPELINLKASKSMDLVPDEGKV ENSRNOP00000039831/1-1203 PHPSLEWGLEDFSHSSRVDSTGYFPDQHVNFRIVTPVGQPESINLKASKSMDLVPDESKV ENSP00000385848/1-1205 PHSALGLGLEDYSHSSGVDSAVYFPDQHINFRSVTPARQPESINLKASKSMDLVPDESKV ENSCPOP00000003953/1-1070 PHPGLEMGLEDYSHSSGVDSAVYFPDQHINFRSMTLARQPESINLKASKSMDLVPDESKV XP_004851228.1/1-1104 PHPSLELGLEDYSHSSGVDSAVYFPDEHINFRSVTPARQPESINLKASKSMDLVADESKL **..* ****:**** ***: ****:*:*** :* . *** ************.**.*: ENSMUSP00000074837/1-1203 QSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNES ENSRNOP00000039831/1-1203 QSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNES ENSP00000385848/1-1205 HSLAGQKSESPSKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNES ENSCPOP00000003953/1-1070 HSLAGPRPESPNRDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPWPHMVRGRGCNES XP_004851228.1/1-1104 HSLAGPRPESPGKDFGPTLGLKKSSSLESLQTAVAEVRKNERPFHRPWPHVIRGRGCNES :***. :.:**.:***************************: ***** **::******** ENSMUSP00000074837/1-1203 FRAAIDKSYDGPEEADADGLSDKSSRSGHTALNCESAPQGNPELDNVENKAKNIKKTKEK ENSRNOP00000039831/1-1203 FRAAIDKSYDGPEEAEADGLSDKSSHSGHTALNCESAPQGNPELDDVENKAKNVKKTKEK ENSP00000385848/1-1205 FRAAIDKSYDGPEEIEADGLSDKSSHSGQGALNCESAPQGNSELEDMENKARKVKKTKEK ENSCPOP00000003953/1-1070 FRAAIDKSYDGPEELDADGLSDKSSHSGQGALNCESAAQGNSELQDLENKARKVKKTKEK XP_004851228.1/1-1104 FRAAIDKSYDGPEELDADGLSDKSSHSGQGALNCESAPQGNSELEDMENKTRKAKKTKEK ************** :*********:**: *******.***.**:::***::: ****** ENSMUSP00000074837/1-1203 EKKKGKGKLKVKEKKLKEEHEDAERKMKRKGFGAMLRFGKKKDDKVGKAEQKGA-QKSGH ENSRNOP00000039831/1-1203 EKKKGKGKMKVKEKKQKEEHEDTERKMKRKGFGAMLRFGKKKDDKVGKTEQKGT-QKSGH ENSP00000385848/1-1205 EKKKEKGKLKVKEKKRKEENEDPERKIKKKGFGAMLRFGKKKEDKGGKAEQKGT-LKHGG ENSCPOP00000003953/1-1070 EKKKEKGKLKVKEKKQKENNEDPERKIKRKGLGAMLRFGKKKDGKRGEAEQKGG-PKPGS XP_004851228.1/1-1104 EKKKEKGKLKIKEKKQKEENEDPERKIKRKGFGAMLRFGKKKDAKSSKAEQKSAPPKQGS **** ***:*:**** **::**.***:*:**:**********: * .::***. * * ENSMUSP00000074837/1-1203 PEEEELERMKEERERIGAKHQELREKQARGLVDYATAVTGPVHDMDDDEMDPNYARVNHF ENSRNOP00000039831/1-1203 PGEEELERMKEERERIGAKHQELREKQARGLVDYATVATGPVHDIDDDEMDPNYARVNHF ENSP00000385848/1-1205 LREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYDMDDDEMDPNYARVNHF ENSCPOP00000003953/1-1070 PRPEEITPTSSAFFRIGAKHQELREKQARGLLDYATGTIGSVHDMDDDEIDPNYARVNHF XP_004851228.1/1-1104 LREEELEKMKEERER--------------------------------------------- **: .. * ENSMUSP00000074837/1-1203 REPCASANVFRSPSPLRAGPLAYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPM ENSRNOP00000039831/1-1203 REPCTSANVFRSPSPPRAGTLGYPRDGRPLSP--DHLEGLYAKVNKPYHPPALADSGRPM ENSP00000385848/1-1205 REPCTSANVFRSPSPPRAGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPT ENSCPOP00000003953/1-1070 REPCASANVFRSPSPPRAGPFGYPRDGRPLSPERDHLEGLYAKVNKPYQPPVPVDSGHPA XP_004851228.1/1-1104 --------------------------------------------------------GRPA *:* ENSMUSP00000074837/1-1203 AGTTDRIQKLRKEYYQARREGFLLYEDENTRARPSDHDLRWVSGKGPDGSTHNLRFEGME ENSRNOP00000039831/1-1203 AGTTDRIQKLRKEYYQARREGFLLYEDEEGVTRPSDYDLHWVSGKGPDGSAHNLRFEGME ENSP00000385848/1-1205 GGSTDRIQKLRKEYYQARREGFPLYEDDEGRARPSEYDLLWVPGRGPDGNAHNLRFEGME ENSCPOP00000003953/1-1070 GGSSDRIQKLRKEYYQARREGFLLYEDDEGRPRPSEYELHWVSGKSPDGNAHNLRFEGME XP_004851228.1/1-1104 GGSTDRIQKLRKEYYQARREGFPLYEDDEGRTRPSDYDLHWVSGKSTDGNAHNLRFEGME .*::****************** ****:: .***:::* **.*:..**.:********* ENSMUSP00000074837/1-1203 RQYASLPRGGSADPVDYLTASPRGRYNDRELPYYPGPHPVHAPRGSYPRPPDLRATDLRY ENSRNOP00000039831/1-1203 RQYASLPRGGSADPVDYLTASPRGRYNERELPYYPGPHPVHSPRGSYPRPPDLRVTDLRY ENSP00000385848/1-1205 RQYASLPRGGPADPVDYLPAAPRGLYKERELPYYPGAHPMHPPKGSYPRPTELRVADLRY ENSCPOP00000003953/1-1070 RQYASLPRAGPADPVDYLTAAPRGLYQERELPYYPGAHPVHPPKGGYARPPELRMTDPRY XP_004851228.1/1-1104 RQYASLPRGGPADPLDYLTSAPRGLYKERELPYYPGAHPVHPPKGGYACPPDLRLTDLRY ********.*.***:***.::*** *::********.**:*.*:*.*. *.:** :* ** ENSMUSP00000074837/1-1203 PQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKN ENSRNOP00000039831/1-1203 PQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGGSPDQYPYRNQDPRQKN ENSP00000385848/1-1205 PQHYPPPPAPQHKGPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKN ENSCPOP00000003953/1-1070 PQYYPPPPVPQHKGPFRQDVPPSPPRHQRMPAYQEMGRAGPRGVSPDRHPYRTQDPRQKN XP_004851228.1/1-1104 PQYYSPPAVPHHKGPFRHDVPPSPPQHQRVLAYQEMGRAGPRGGSPDRHPYRTQDPRQKN **:*.**.. :******:*******:***: .*** **.**** ***::***.**.**** ENSMUSP00000074837/1-1203 PMTAAV ENSRNOP00000039831/1-1203 PMTAAV ENSP00000385848/1-1205 PMTAAV ENSCPOP00000003953/1-1070 PMTAAV XP_004851228.1/1-1104 PMTAAV ******