CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000003635/1-581 ------------------------------------------------------------ XP_004855892.1/1-579 ------------------------------------------------------------ ENSP00000327916/1-579 ------------------------------------------------------------ ENSMUSP00000063416/1-578 ------------------------------------------------------------ ENSRNOP00000043828/1-954 MLMPVSISGEPRTSERQAASSSKGVQSSSIDRLQGAAGEIDFSQTYTDGERGARRARSTQ ENSCPOP00000003635/1-581 ------------------------------------------------------------ XP_004855892.1/1-579 ------------------------------------------------------------ ENSP00000327916/1-579 ------------------------------------------------------------ ENSMUSP00000063416/1-578 ------------------------------------------------------------ ENSRNOP00000043828/1-954 ALHTAWQQPYSKRQGTERSRLESLGSAGKQVNETESKTLNFVSVYNLFISPSGHPELSFE ENSCPOP00000003635/1-581 ----------------------------MRLWLRGPDLRAPRSSWEFCRVYTQLSPLPAP XP_004855892.1/1-579 ----------------------------MRLWLRGLGLQALRNFREFCGVHTQLPPLPVP ENSP00000327916/1-579 ----------------------------MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVP ENSMUSP00000063416/1-578 ----------------------------MRLWLRGLACQALRSSWGVCRIHTQPPPPPIP ENSRNOP00000043828/1-954 DPTESMHQWTPEVTPAQIPAIRQKVTEDMRLWLRGLVYQARRSSWGVFRIHTQPPPPPIP ** *** :* *. . : : .* * * ENSCPOP00000003635/1-581 QKILAGWEAISLGRQPVPEYFNFAHDVLDMWAQQEKAGHRPSSPAFWWVDGKGAEVKWSF XP_004855892.1/1-579 EKILAVWEAISLGRQPVPEYFNFAHDVLDMWAQLEKAGHRPSCPAFWWLDGRGAEVKWSF ENSP00000327916/1-579 QKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSF ENSMUSP00000063416/1-578 E-VVATWEAISLGRQPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTF ENSRNOP00000043828/1-954 E-VVATWEAISLGKRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTF : ::* *******:: *************:*:: *::****. *****::* *:*:**:* ENSCPOP00000003635/1-581 DELGMQSRKAANILEKVCSLKPGDRMMLVLPRLPEWWLVSVACMRTGVVMIPGVSQLTEK XP_004855892.1/1-579 AELGTQSRKAANVLGDACGLQPRDRMILVLPRLPEWWLISVACMRTGVVMIPGVSQLTEK ENSP00000327916/1-579 EELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEK ENSMUSP00000063416/1-578 EELGKQSRKAANVLEGVCGLQPGDRMMLVLPRLPDWWLISVACMRTGVVMIPGVSQLTAK ENSRNOP00000043828/1-954 EELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQK *** *******:* .*.*:* **::*******:*** *******.*****::*** * ENSCPOP00000003635/1-581 DLKYRLQVSRAKSIITSDSLAPHVDAISAECPSLQAKLLVSDASRPGWMNFRELLQEAST XP_004855892.1/1-579 DLKYRLQMSRAKSIVASDSLAPHVDAISAECPSLQTKLLVSDSSRPGWVNFRELLQEASA ENSP00000327916/1-579 DLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREAST ENSMUSP00000063416/1-578 DLKYRLQAARAKSIVTSDALAPQVDAISADCPSLQTKLLVSDTSRPGWINFRELLRAASP ENSRNOP00000043828/1-954 DLKYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASP ******* :*.***::**:***:******:*****::*****:*****:******: **. ENSCPOP00000003635/1-581 EHSCVRTKSGDPMSIYFTSGTTGAPKMVEHSQCSYGLGFVASGSRWMGLTGSDIFWNTTD XP_004855892.1/1-579 EHSCVRTKSGDPLVIYFTSGTTGAPKMVEHSQCSYGLGFVASGSRWLGLTGSDVFWNTSD ENSP00000327916/1-579 EHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTD ENSMUSP00000063416/1-578 EHNCVRTRSGDSVAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWMALTESDIFWNTTD ENSRNOP00000043828/1-954 EHNCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWNTTD **.*:**:* *.: *********:********.********** * :.** **:****:* ENSCPOP00000003635/1-581 TGWVKAAWSLFPTWAIGSCLFVHEMPRVDTKVILNHYDENPITNFCCVPTIFRLLVQEDL XP_004855892.1/1-579 TGWVKAGWSFFPTWAMGSCVFVHEMPRVDTKVILNTLSTYPITNFCCVPTIFRLLVQEDL ENSP00000327916/1-579 TGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDL ENSMUSP00000063416/1-578 TGWVKAAWTLFSAWSNGACIFVHELPRVDAKTILNTLCRFPITTLCCVPTLFRLLVQEDL ENSRNOP00000043828/1-954 TGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDL ******.*::*.:*. *:*:****:*:**::.*** ***.:*****:********* ENSCPOP00000003635/1-581 TRERYQFRSLRHCLTGGEALNPDVREKWKCHTGLELHEGYGQSETVPICANARGTKIKSG XP_004855892.1/1-579 T--RYQFQSLQHCLAGGEALNPDVRDKWKRHTGLELHEGYGQSETVAICANARGTKIKSG ENSP00000327916/1-579 T--RYQFQSLRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSG ENSMUSP00000063416/1-578 T--RYKFQCLRHCLTGGEALNPDVRDKWKSQTGLELHEGYGQSETVVICGNSRNSTIKSG ENSRNOP00000043828/1-954 T--RYKFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSG * **:*:.*:***:******.***:*** :**:*::********* **.* :. .**** ENSCPOP00000003635/1-581 SMGRASPPYDVQIVDDEGNVLPPGEAGNIAVRIRPTRPFCFFHCYLDNPEKTAASEQGDF XP_004855892.1/1-579 SMGQASPPYDVQIVDDEGNVLPPGEEGNIAVRVRPTRPFCLFNYYLDNPEKTAASEQGDF ENSP00000327916/1-579 SMGKASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDF ENSMUSP00000063416/1-578 SMGKASPPYDVQIVDEEGNVLPPGKEGNIAVRIKPTRPFCFFNCYLDNPEKTAASEQGDF ENSRNOP00000043828/1-954 SMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKTAASEQGDF ***:***********:********: **:*:*::******:*: **************** ENSCPOP00000003635/1-581 YITGDRGRMDTDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLECAVASSPDPIR XP_004855892.1/1-579 YITGDRGRMDTDGYFWFMGRNDDVINSSSYRIGPVEVESVLAEHPAVLECAVVSSPDPIR ENSP00000327916/1-579 YITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIR ENSMUSP00000063416/1-578 YITGDRAHMDEDGYFWFLGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIR ENSRNOP00000043828/1-954 YITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIR ******.:** ******:*********************.*********.**.******* ENSCPOP00000003635/1-581 GE--------------------------------VVKAFIVLSPAYSSHDPEALTRELQE XP_004855892.1/1-579 GE--------------------------------VVKAFIVLSPAYYSHDPEALTRELQE ENSP00000327916/1-579 GE--------------------------------VVKAFIVLTPAYSSHDPEALTRELQE ENSMUSP00000063416/1-578 GE--------------------------------VVKAFIVLSPAYASHDPEALTRELQE ENSRNOP00000043828/1-954 GEKNLEVNAIGIGKELPPGLYILWELVLASNGAIVVKAFIVLSPAYVSHDPEALTRELQE ** ********:*** ************* ENSCPOP00000003635/1-581 HVKRVTAPYKYPRK-----------------VAFVSEL---------------------- XP_004855892.1/1-579 HVKRVTAPYKYPRK-----------------VAFVSEL---------------------- ENSP00000327916/1-579 HVKRVTAPYKYPRK-----------------VAFVSEL---------------------- ENSMUSP00000063416/1-578 HVKTVTAPYKYPRK-----------------VAFISEL---------------------- ENSRNOP00000043828/1-954 HVKTVTAPYKYPRKDTCHFLLHEGIWKPMTYINFITSLQILTLNQEFSNESLLPNPMGER *** ********** : *::.* ENSCPOP00000003635/1-581 ---------------------------------------------------------PKT XP_004855892.1/1-579 ---------------------------------------------------------PKT ENSP00000327916/1-579 ---------------------------------------------------------PKT ENSMUSP00000063416/1-578 ---------------------------------------------------------PKT ENSRNOP00000043828/1-954 AQCPDSNTECPNTPEKQDLDLKSHLIMMMKDIQNSLREMQENTNEQVEAYRQEMQKIPQR *: ENSCPOP00000003635/1-581 VSGKIQRS-------------------------------------KLRKQE--------- XP_004855892.1/1-579 VSGKIQRS-------------------------------------KLRNQE--------- ENSP00000327916/1-579 VSGKIQRS-------------------------------------KLRSQE--------- ENSMUSP00000063416/1-578 VSGKILRS-------------------------------------KLRNQE--------- ENSRNOP00000043828/1-954 IIGKHNQTGEGIKNGNRSNKAQRETILDIENQRKRQGAVDTSITNKMKEIEDRISGAEDS : ** :: *::. * ENSCPOP00000003635/1-581 -------------WGR----------------------------------------- XP_004855892.1/1-579 -------------WAR----------------------------------------- ENSP00000327916/1-579 -------------WGK----------------------------------------- ENSMUSP00000063416/1-578 -------------WGR----------------------------------------- ENSRNOP00000043828/1-954 IEIIDTTVKDNGKWKKTLAQNIQEIQDTMRRSNLRIIGIEESEESQLKEPVNTSTKS * :