CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000003554/1-869 ------------------------------------------------------------ XP_004852666.1/1-931 MATPRGAPPRFFRFLPDVLVDNIPQKGERPSQGSISSRRAVTLPPPTRSFCVSSSPLGAR ENSP00000350228/1-904 ------------------------------------------------------------ ENSMUSP00000107106/1-862 ------------------------------------------------------------ ENSRNOP00000011467/1-860 ------------------------------------------------------------ ENSCPOP00000003554/1-869 ------MFPPLETELKQPLPDPYDDFMYRHLQYYGYFQ-GSGVEALSSL--------VSC XP_004852666.1/1-931 APCGGSMFPALKTELQQPLPDPYEDFMRRHLQYYGYFRVQSGRPPSPVP-------PPPG ENSP00000350228/1-904 ------MFPALETHLKQTIPDPYEDFMYRHLQYYGYFKAQRGSLPNSATHQHVRKNNPQC ENSMUSP00000107106/1-862 -----MNVLLEMAFLSQTLPDPYEDFIHHHLQYYGYFKAQKSSLPNSGTHQRVWRNSPRY ENSRNOP00000011467/1-860 ------MFCLRMAFLSQTLPDPYEDFMHHHLQYYGYFKAQKSSLPSSATHQRVWRSSPRY . : *.*.:****:**: :********: . . . ENSCPOP00000003554/1-869 ---GPEGEHLESFSGSLSKECFLFPLIHFLTCCMTLSLVSLSVFAPLLPQWMQWCRGPSE XP_004852666.1/1-931 PKSGRPREREPVTRAALPKET---PQ---------------------------------- ENSP00000350228/1-904 LLNGSLGEKDDLIPDTLQKEKLLWPI--SLSSAVHRQIEAINRDFHSCLGWMQW-RGLSS ENSMUSP00000107106/1-862 MLNGSFGERDDFISDSLEKEMLLWPT--CLSSTGHAHIDAVNR----------------- ENSRNOP00000011467/1-860 MLNGSFGERDDFISDSLEKEMFLYCR--CLSSVEQPEREGCSS----------------- * *: :* ** ENSCPOP00000003554/1-869 PQGPAGEAGVSPICIILTLYSCDCIMLTPSSPRVRSRQLLYNSDDKADRGAPRLREPREL XP_004852666.1/1-931 ----------------------GRRSLSP--ARVRSRQLLY---DEPDSATPRLREPREL ENSP00000350228/1-904 LQPPPPRFKDSPASAFRVAGITDSHMLSL--PHLRSRQLLY---DELDEVNPRLREPQEL ENSMUSP00000107106/1-862 ----------------------DSLLLSS--PLLRTRQLIF---DELDEASPRLREPREL ENSRNOP00000011467/1-860 ----------------------DSLMLSS--PLLRSRQLLY---DELDTVNPRLREPREL . *: . :*:***:: *: * ******:** ENSCPOP00000003554/1-869 FPILPGWGPVQAPRWPVECEVIQEKVRHIEWVPPEPEYFYQPTGNEKVPEIVGEEKGTIV XP_004852666.1/1-931 FPVLSGRGPLQAPRWPVECEVIRERVQHIEWVPPEPEYFYQSTGNEKVPEIMGEEKGTVV ENSP00000350228/1-904 FSILSTKRPLQAPRWPIECEVIKENIHHIEWAPPQPEYFYQPKGNEKVPEIVGEKKGTVV ENSMUSP00000107106/1-862 FSCFSSRGPLQAPRWPIECEVIKENIHHIEWVPHQPEYFYQPTGSEKVPEIVGEEQGTVV ENSRNOP00000011467/1-860 FSCFSNKGPLQAPRWPIECEVIKENIHHIEWVPLQPEYFYQPTGNERVPEIVGEEQGTVV *. :. *:******:*****:*.::****.* :******..*.*:****:**::**:* ENSCPOP00000003554/1-869 YQLQSVPTEGSYFTSSRVGGKRGAIQQLAVSLCGPEDDTLLFESRFESGNLQKAVRVDTY XP_004852666.1/1-931 YQLQSVPTEGSYFTSSRVGGKRGSVQQLAVSLHGPEDDTLLFESRFESGNLQKAVKVAAY ENSP00000350228/1-904 YQLDSVPIEGSYFTSSRVGGKRGIVKELAVTLQGPEDNTLLFESRFESGNLQKAVRVDTY ENSMUSP00000107106/1-862 YQLDSVPAEGTYFTSSRIGGKRGTIKELAVTLQGPDDNTLLFESRFESGNLQKAVRVGIY ENSRNOP00000011467/1-860 YQLDSVPTEGSFFTSSRIGGKQGVIKELAATLQGPEDNTLLFESRFESGNLQKAVRVGIY ***:*** **::*****:***:* :::**.:* **:*:*****************:* * ENSCPOP00000003554/1-869 EYELTLRPDLYTSRHTQWFYFRVQNTRRDVPYRFTIVNLLKPRSLYAAGLRPLLYSQRDA XP_004852666.1/1-931 EYELTLRPDLYTDRHTQWFYFRVQNTRKDVRYRFTIVNLRKPRSLFAVGLRPLLYSQRDA ENSP00000350228/1-904 EYELTLRTDLYTNKHTQWFYFRVQNTRKDATYRFTIVNLLKPKSLYTVGMKPLLYSQLDA ENSMUSP00000107106/1-862 EYELTLRTDLYTDKHTQWFYFRVQNTRKDATYRFTIVNLLKPKSLYAVGMKPLMYSQLDA ENSRNOP00000011467/1-860 EYELTLRTDLYTDKHTQWFYFRVQNTRKDVTYRFTIVNLLKPKSLYAVGMKPLMYSQLDA *******.****.:*************:*. ******** **:**::.*::**:*** ** ENSCPOP00000003554/1-869 CSRGVGWRREGGDIRYY------------CLTWTARFPHDRDTCFLAHGYPYTYSDLQGY XP_004852666.1/1-931 CSSRVGWRREGGDIRYFRGGTGS-----YCLTWTARFPHDRDTCFWAPGYPYTFSDLTRY ENSP00000350228/1-904 NTRNIGWRREGNEIKYYKNNTDDGQQPFYCLTWTIQFPYDQDTCFFAHFYPYTYTDLQCY ENSMUSP00000107106/1-862 TIYNIGWRREGREIKYYKNNVDDGQQPLYCLTWTTQFPHDQDTCFFAHFYPYTYTDLQCY ENSRNOP00000011467/1-860 TIYNIGWRREGHEIKYYKNNMDDGPQPLYCLTWTIQFPHDQDTCFFAHFYPYTYTDLQCY :****** :*:*: ***** :**:*:**** * ****::** * ENSCPOP00000003554/1-869 LRAVARDPAQARLCKLRALCRSLAGNPVYLLTIT-----------KRAVVLSARVHPGES XP_004852666.1/1-931 LRAAARDPARARVCRLRALCCSLAGNPVYLLTVTNPARGPQAAAAKRAVVLSARVHPGES ENSP00000350228/1-904 LLSVANNPIQSQFCKLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVHPGES ENSMUSP00000107106/1-862 LLSVANNPIQSQFCKLRALCRSLAGNTVYLLTITNPSRTPQEAAAKKAVVLSARVHPGES ENSRNOP00000011467/1-860 LLSVANNPIQSQFCKLRALCRSLAGNTVYLLTITNPSRTPQEAAAKKAVVLSARVHPGES * :.*.:* :::.*:*::** *****.*****:* *:************* ENSCPOP00000003554/1-869 GGSWVMRGFLDFILGGSPDAQLLRDLFVFKVVPMLNPDGVIVGNHRCSLAGRDLNRHYRT XP_004852666.1/1-931 AGSWVMRGFLDFILGSSPDAQLLRDLFVFKVVPMLNPDGVIVGNHRCSLSGRDLNRHYRT ENSP00000350228/1-904 NGSWVMKGFLDFILSNSPDAQLLRDIFVFKVLPMLNPDGVIVGNYRCSLAGRDLNRHYKT ENSMUSP00000107106/1-862 NSSWIMNGFLDFILSNSPDAQLLRDIFVFKVIPMLNPDGVIVGNYRCSLAGRDLNRHYKT ENSRNOP00000011467/1-860 NSSWIMNGFLDFILSDSPDAQLLRDIFVFKVIPMLNPDGVIVGNYRCSLAGRDLNRHYKT .**:*.*******..*********:*****:************:****:********:* ENSCPOP00000003554/1-869 LLKDAFPCVWYTRNMIQRLLEEREVLLYCDFHGHSRKNNVFLYGCSSSDHKRWLHERVFP XP_004852666.1/1-931 LLKDAFPCIWYTRNMVQRLLEEREVLLYCDFHGHSRKNNVFLYGCSSNSRRHWLHERVFP ENSP00000350228/1-904 ILKESFPCIWYTRNMIKRLLEEREVLLYCDFHGHSRKNNIFLYGCNNNNRKYWLHERVFP ENSMUSP00000107106/1-862 VLKDSFPCIWYTKNMIKRLLEEREVLLYCDFHGHSRKNNIFLYGCHSNNRKHWLHERVFP ENSRNOP00000011467/1-860 VLKDSFPCIWYTKNMIKRLLEEREVLLYCDFHGHSRKNNIFLYGCHSNNRKHWLHERVFP :**::***:***:**::**********************:***** ...:: ******** ENSCPOP00000003554/1-869 LMLSKNAPDTFSFQSCNFKVQKSREGTGRVVMWRMGIRNSYTLESTFGGSTLGSKRDTHL XP_004852666.1/1-931 LMLSKNAPEKFSFQSCNFKVQKNREGTGRVVMWRMGIRNSYTLESTFGGSTLGSRRDTHL ENSP00000350228/1-904 LMLCKNAPDKFSFHSCNFKVQKCKEGTGRVVMWRMGILNSYTMESTFGGSTLGNKRDTHF ENSMUSP00000107106/1-862 LMLSKNAPDKFSFDSCNFKVQKCKEGTGRVVMWRMGIINSYTMESTFGGSTLGSKRDTHF ENSRNOP00000011467/1-860 LMLSKNAPDKFSFDSCNFKVQKCKEGTGRVVMWRMGIINSYTMESTFGGSTLGSKRDTHF ***.****:.***.******** :************* ****:**********.:****: ENSCPOP00000003554/1-869 TTEDLKALGRHICDTLLDFCDPDQTKFIQCLAELMELVHQEIHKKLSELGQDRNLEESWS XP_004852666.1/1-931 TTEDLKALGHHICDTLLDFCDPDQTKFIQCLAELTELVHQEIHRKLSELGQDVNLEENWS ENSP00000350228/1-904 TIEDLKSLGYHVCDTLLDFCDPDQMKFTQCLAELKELLRQEIHKKFHELGQDVDLEGSWS ENSMUSP00000107106/1-862 TIEDLKSLGYHVCDTLLDFCDPDQTKYTQCLQELKELLQQEINKKLNNFGQDMDLEGNWS ENSRNOP00000011467/1-860 TIEDLKSLGYHVCDTILDFCDPDQTKYTQCLQELKELLQQEIHKKLNNFGQDMDLEGNWS * ****:** *:***:******** *: *** ** **::***::*: ::*** :** .** ENSCPOP00000003554/1-869 DIHLSDIESSNSTSGSDSSLSDGLPAHLLNRAEKMNQKMKIFQKKKKKPLQTRRQRNAHY XP_004852666.1/1-931 DIHLSDIES--STSGSDSSLSDGLPAHLLHRAEEVSQKIKMFQKKKKKPLQTRKQRNEQY ENSP00000350228/1-904 DISLSDIESRNSTSGSDSSLSDGLPVHLANIADELTQKKKMFKKKKKKSLQTRKQRNEQY ENSMUSP00000107106/1-862 DIPLSDIES--STSGSDSSLSDGPPIRLLNIVADEPNQKTVLKNPKKKRLQTRKQRNEQY ENSRNOP00000011467/1-860 DIPLSDIES--STSGSDSSLSDGPPIRLLSIADELHQKM-VLKNPKKKRLQTRKQRNEQY ** ****** ************ * :* . . :: :::: *** ****:*** :* ENSCPOP00000003554/1-869 HNSSLT-EIRFPGDSH--VRARFATTLQKQLAFPKHPENGSSSAGTQGRARLHQPQSSRR XP_004852666.1/1-931 QNSNSKRFGRGLAGGPLEGRASFATTLQKQPAFLKQLENPGPAAVTQEKVRRQQTQLSGR ENSP00000350228/1-904 QKKNLMQKLKLTEDTS--EKAGFASTLQKQPTFFKNSENSSFLPMKNENPRLNETNLNRR ENSMUSP00000107106/1-862 QKSYLMRELKLTENAP--GRARFVSTLQKQPTFLKSPESPSPSVRRSENPRLNETQLSGR ENSRNOP00000011467/1-860 QKNYLMRELKLTENAP--GRARFASTLQKQPTFLKSPENSSPSIRRSEKPRLNETQLSGR ::. : . :* *.:***** :* * *. . . . * ::.: . * ENSCPOP00000003554/1-869 DPAAAPAQPMPPPILPEHERTHQT------------------------------------ XP_004852666.1/1-931 GRDAAPAQPAPPLIRPKDKERVQQVQHLTAMPTVNAVVSAFRRLRQEDHCKFEASLGHIG ENSP00000350228/1-904 DKDTPLDPSMATLILPKNKGRMQN------------------------------------ ENSMUSP00000107106/1-862 EKGTSLD---PPLTSPKNKERIQS------------------------------------ ENSRNOP00000011467/1-860 EKGTSLD---APLTSPKTKEITQS------------------------------------ :. .. *: : * ENSCPOP00000003554/1-869 KRPVLYRNGPRAPQSRSGASQEPGPVSQRD---------RKRGSSLVAYPALHVCTYP-- XP_004852666.1/1-931 QKPGA--PASLAPRSLSSARGEPAPGAQPG---------RRRGGSLVAYPALHVCTYPCP ENSP00000350228/1-904 KKPGF--TVSCSPKRTINSSQEPAPGMKPNWPRSRYPATKRGCAAMAAYPSLHIYTYP-- ENSMUSP00000107106/1-862 KKPGF--TASCSPKRSTNSSLGPAPDVKPNWSKTRYSATRKDHATMAVYPSLHIYTYP-- ENSRNOP00000011467/1-860 KKPGF--TASCSPKRSTNSSLGPAPDAKPNWPRTRYPASRKDHAAMAGCPSLHVYTYP-- ::* . :*: .: *.* : . :: .::. *:**: ***