CLUSTAL W(1.81) multiple sequence alignment ENSP00000335612/1-469 MDNRNTQMY--------------------------------------------------- ENSMUSP00000053080/1-681 MENRNTHTHPESKADAPAVQSSSGLSSTKKKTDSEPTVSAGQTGLADATERDNRKQPVAP ENSRNOP00000012147/1-685 MENRNTHTHPENKAEAPTVQSSSGLSSTKKKTDLEAAVAAGQNGRADATERDSRKKPAAP XP_004851118.1/1-598 MDNRNTQMDTEDRTEDTGLQPHPVLSPTRQRADDSTMSAVSQD----------------- ENSCPOP00000003470/1-484 ------------------------------------------------------------ ENSP00000335612/1-469 ------------------------------------------------------------ ENSMUSP00000053080/1-681 RGPERELRPTGSSQDGSGELPTQE--PSARPRTTQDGPRELQAGPEQVQPSGDFVASEGR ENSRNOP00000012147/1-685 RGPEKEPRHTASSQERSGEPQTQEQRPSARSKTTQDGPRELQTGQEQARPSGDFVASEGR XP_004851118.1/1-598 -------------------------------------PKCLSPGQQAVNGLGTMH----- ENSCPOP00000003470/1-484 ------------------------------------------------------------ ENSP00000335612/1-469 ------------------------------------------------------------ ENSMUSP00000053080/1-681 PQPAMQTKDQQKRWQSAEVKEILLAESCQGNTDHDLGKPRPSNSRSQPLKNNSPSEAGRP ENSRNOP00000012147/1-685 PQPAMQTKDQQKRWQSAEAKDVQSTESCQGNTDHDLGKPCTSDSRSHPQKTNSLSEGGRP XP_004851118.1/1-598 -----------------------LTVPC-----------CALDSHVHPLGEDPLREAGNP ENSCPOP00000003470/1-484 -----------------------LTEPC-----------SALDSCVQPLGDDPFGEAGDP ENSP00000335612/1-469 ------------------------------TEEEKTVNPFLPSTPGPKKAKGGGEAVETH ENSMUSP00000053080/1-681 QVRLQEPMPAPGSGTHKDNPQEAVPPKPKVTAEEKKAPPVLPSVPGPRTHKDRGEAAEIR ENSRNOP00000012147/1-685 QARLQEPMPAPSSGTHKDNPQEAVPPKPKVTAEEKKAPPVLPTV--PRTHKDRGEAVESK XP_004851118.1/1-598 RIRPQEALPEPSAGGREGSSQGAMHSMPLATAEEKTAMSLLPSTLGPKAPQEGGGCRDPA ENSCPOP00000003470/1-484 ----QEAPPKPAARGHEGSYQGAMCPMPMTTAEENIAMSPLPPTLGLKAPREEGETAETQ * **: . . **.. : : * : ENSP00000335612/1-469 ---------PAPGPL---------PPP--------------------EVRDIGERREPDR ENSMUSP00000053080/1-681 ATLR-----LQPPPP---------PLP--------------------EERDT-EKKELGQ ENSRNOP00000012147/1-685 ASPRPPPPPPSPPPP---------PPP--------------------EERDV-EKKELGQ XP_004851118.1/1-598 STKA-----SSPNSKTGMGTEMGWEGPEEEGETKMRQYWESSGEGMSEGRDISDRREPGH ENSCPOP00000003470/1-484 AAPRPLPAACNPRPL---------PCPQ-------------------EARDIDERRELGP * . * * ** :::* . ENSP00000335612/1-469 AQQQPQKPAVAAGTQSLGNFRQGFMKCLLEVEK-MEASHRRASKARSQTAQKSPRTLTPV ENSMUSP00000053080/1-681 GQKQRQQALSAAGTQGPANSRRGFMKCLLEVEEQEEATHRRTLKSRGLTARRSPKTVTSV ENSRNOP00000012147/1-685 GQKQRQPALAAAGTQGPGNFRRGFMKCLLEVEEQEEATHRRTLKSRALTARRSPKTVTSV XP_004851118.1/1-598 TQE----------FESPGNPQPSFMECLLETEE-EEVAHRRAWKSRALTAWKSPRTLMPG ENSCPOP00000003470/1-484 TQE----------SEKPGSLWPGFMKCLLEVEE-EEAAHRRAWKARALTARKSLRTLTPG *: : .. .**:****.*: *.:***: *:*. ** :* :*: . ENSP00000335612/1-469 PTSAP---SLPQTP-------ASVPASGPSWARLPAPGPEPAPMGAPVPTSMPCPVLLGP ENSMUSP00000053080/1-681 STSGPISSSVPTLPLTLHEPSTSAPASVPSWVRPPAPGQTPIPMGS------PGSVLPTS ENSRNOP00000012147/1-685 PTSGPVNSSVPPLPPTLHEPSTSAPATVPSWVKPPAPGQAPIPMGT------PSSVLPTP XP_004851118.1/1-598 PTSVPISHSAP---LTLPQTPTSAPPTTWVWARPPA----ATLMAALVPAMVPDLVLWAP ENSCPOP00000003470/1-484 PTSVPISHSAP--------------------------------------------LLRGP .** * * * :* . ENSP00000335612/1-469 ALDLGWRRMELLHQSSERTLSYAKA-RQEPEEQSLQKLYQN-RE--KSEEQLTLKQEEAF ENSMUSP00000053080/1-681 AQDQNWRWPEFLPQGNERTLTYAKILRQEPEEHSLFRMYQSWEE--RTEEHLTLKQEEAF ENSRNOP00000012147/1-685 AQDQSWRWPELLPQGNERNLNYAKT-RQESEEHGLFKLYQNWEE--RTEEHLTLKQEEAF XP_004851118.1/1-598 IPDLGWRWTE-LPKSRKWSLSCARP-WQEPEEHGLLGLCQGWKE--QAEEHLILKQEEAF ENSCPOP00000003470/1-484 FSDLGWRWTELLPQSHEWSLSCSRP-WQELEEHSLFRLSQVWEEQAQAEEPLTLKQEEAF * .** * * :. : .*. :: ** **:.* : * .* ::** * ******* ENSP00000335612/1-469 RSYFEIFNGPGEVDAQSLKNILLL-MGFSVTLAQVEDALMSADVNGDGRVDFKDFLAVMT ENSMUSP00000053080/1-681 RSYFDIFNGPGEVDARSLKNILLL-IGFTFTPAQVEEALMSADVNGDGHVDFKDFLAVMT ENSRNOP00000012147/1-685 RSYFDIFNGPGEVDARSLKNILLL-IGFTFTPAQVEEALMSADVNGDGHVDFKDFLAVMT XP_004851118.1/1-598 RSYFEIFNGPDEVDAQSLKNILVHCIFFSLSLS------LSLSLSGDGHMDFKDFLAMMT ENSCPOP00000003470/1-484 HSYFEIFDGPGELDAQSLKSILVL-TGFSLTPAQVEAALISADVDGDGHVDFKDFLAVMT :***:**:**.*:**:***.**: *:.: : :* .:.***::*******:** ENSP00000335612/1-469 DTRRFFCSVEQNALSDMAPHNPHTLLFEILSLLVEMLALPEAVLEEITNYYQKKLKEGTC ENSMUSP00000053080/1-681 DTKRFFCSVEQNVLMDMSPRNPYTLFFEILSLLVEMLALPELALEEITNYYQKKLKEGSS ENSRNOP00000012147/1-685 DTKRFFCSVEQNVLMDMSPPNPYTLFFEILSLLVEMLALPEVALEEITNYYQKKLKEGSS XP_004851118.1/1-598 DTRSFFCSMEQNDVTNMAPPNPHTLLFEILSLLVELLALPKTVLEEITNYYQ-KLKEGTC ENSCPOP00000003470/1-484 DTRRFFCSVEQNVVTNMASPNPYDLIFKNLNLLFPYVQLHTPILEQVPYYYQKKLKAGTC **: ****:*** : :*:. **: *:*: *.**. : * **::. *** *** *:. ENSP00000335612/1-469 KAQEMEAAVGRLRLQK-LPYNPQQEESSEVPERKVLSILSRLKQQNY----APNLQSPYA ENSMUSP00000053080/1-681 KAREMESAMGGLRQRKKIPYNPQQVENLEVPERRVLRILSRLKQQNY----AANLQSPYA ENSRNOP00000012147/1-685 KAREMETAMGGIRQRKKIPYSSQQVENLEVPERRVLRILSRLKQQNY----AANLQSPYA XP_004851118.1/1-598 EVREMASAIGQLWLQKQVLYNHQQAGSLEVPERRGLSILSRLKQNVE--DLASDLQSPYA ENSCPOP00000003470/1-484 RAREMASTTSQLRSQKQLPYNLQLAERSEVPEHRVLSILSRLKQNVYPPPPASDLRSPYA ..:** :: . : :* : *. * ****:: * *******: *.:*:**** ENSP00000335612/1-469 QVPCILLCPQLDKKMVRRQPSNHY--ALDQCTPPGLDPDIRSPFFQSGSQGNREHNSDSR ENSMUSP00000053080/1-681 QVPCIPLCPRLDKKAVRRKLASHNHSVLDQCVSTSLGPDFHGLFFQPGQQGSREHSSDSR ENSRNOP00000012147/1-685 QVPCIPLCPRLDKKAVRRKQASHNHSVLDQCVPTSLGPDLHGFFLQPGQQGSREHSSDSR XP_004851118.1/1-598 QMPCIPLCTWLNKKTVHRKLGSHN--MLDQCVPASLSPSTRSLFFQSGPQG--EHRSKRG ENSCPOP00000003470/1-484 QVPGNLLCPRL--KIARWKQGSH---MLDQCTPGSLSPSSRSHLLQSGPHGSREHSSDGG *:* **. * * .: : ..* ****.. .*.*. :. ::*.* :* ** *. ENSP00000335612/1-469 -KWLSSVPARTH ENSMUSP00000053080/1-681 -KWLSSMPARTH ENSRNOP00000012147/1-685 -KWLSSVPARTH XP_004851118.1/1-598 -KWLSSMPTRTH ENSCPOP00000003470/1-484 AKWLSSLPTRTY *****:*:**: