CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000047210/1-950 ---------MDTCGVGYVALGEADPVGSMIVVDSPGQEELSQLDVKA-SETSGVEASIEM ENSRNOP00000057753/1-953 ---------MDTCGVGYVALGEADPVGSMIVVDSPGQEELNQLDVKASSETSSVEASIEM ENSP00000352536/1-911 ---------MDTCGVGYVALGEAGPVGNMTVVDSPGQEVLNQLDVKTSSEMTSAEASVEM ENSCPOP00000003466/1-919 QGRPFWGVLMDTCGVGCVALGEAGPVGNMTVVDSPGQEVLKQLGVKAPSETASMEASIEM XP_004839248.1/1-910 ---------MDTCGVGCVALGEAGPVGNMTVVDSPGHELLNQLGVKAPSETTRVEASIEM ******* ******.***.* ******:* *.**.**: ** : ***:** ENSMUSP00000047210/1-950 SLPPPLPGFEDSSD-RRLPPDQESLTRLEQQDLSSEMSKVSNTRASKPSGRRGGRTARGA ENSRNOP00000057753/1-953 SLPPPLPGFEDSSDKRRLPPDQESLTRLEQQDLSSEMAKVSNPRASKPSGRRGGRTPRGA ENSP00000352536/1-911 SLPTPLPGFEDSPDQRRLPPEQESLSRLEQPDLSSEMSKVSKPRASKPGRKRGGRTRKGP ENSCPOP00000003466/1-919 SLPTPLPGFEDCPDMRSLPPEQESLSRLEQQDLSSEMSKVSNPRASKPGRKRGGRTRKGP XP_004839248.1/1-910 SLPTPLPGFEDSPDKRNLPLEQESLSRLEQQDLSSEMSKVSNPRASKPARKRGSRTRKGP ***.*******..* * ** :****:**** ******:***:.*****. :**.** :*. ENSMUSP00000047210/1-950 KRPQQRKPPSTPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRP ENSRNOP00000057753/1-953 KRPQQRKPPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPHPKRP ENSP00000352536/1-911 KRPQQPNPPSAPLVPGLLDQSNPLSTPMPKKRGRKSKAELLLLKLSKDLDRPESQSPKRP ENSCPOP00000003466/1-919 KRPQQRKAPTAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPPSKRP XP_004839248.1/1-910 KRPQQRKAPSAPLVPGLLDQSNPLSTPMPKKRSQKSKGDLLLLKLSKGLDQPESPPSKRP ***** :.*::*********************.:***.:********.**:*** .*** ENSMUSP00000047210/1-950 PEDFETPSGERPRRRAAQVVSLPNPGWPRTCDPPTSASRVLGLQACATTPGSPSHFSQTS ENSRNOP00000057753/1-953 PEDFETPSGERPRRRAAQVVSLPNPGWPRTCDPPNSASRVLGLQACATTPGSPSHFSQTS ENSP00000352536/1-911 PEDFETPSGERPRRRAAQV----------------------------------------- ENSCPOP00000003466/1-919 PEDFETSSGERPRRRAAQV----------------------------------------- XP_004839248.1/1-910 PEDFETPPGERPRRRAAQV----------------------------------------- ******..*********** ENSMUSP00000047210/1-950 PRALLYLQELAEELSTALPAPPLSGPKSPKVSSPTKPKKTRQASSQ--GEE-DGSARDED ENSRNOP00000057753/1-953 PRALLYLQELAEELSTALPA-PLSGPKSPKVSSPTKPKKTRQAASQ--GEE-DGRARDED ENSP00000352536/1-911 --ALLYLQELAEELSTALPA-PVSCPEGPKVSSPTKPKKIRQPAACPGGEEVDGAPRDED ENSCPOP00000003466/1-919 --ALVYLQELAEELSSTLPA-PVTCPKSPKASSPTTVKKTQPQAACHGGEE-DAAAQDED XP_004839248.1/1-910 --ALVYLQELAEELSSTLPA-PVTCPKSPKASSPTKLKKTPQEAACQGGEE-DATPQDED **:**********::*** *:: *:.**.****. ** :: *** *. .:*** ENSMUSP00000047210/1-950 FVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPV ENSRNOP00000057753/1-953 FVLQVEGEDEEESEAPSENSSDPEPVAPRSTPRGPAAGKQKPHCRGMAPNGLPNYIMAPV ENSP00000352536/1-911 FFLQVEAEDVEESEGPSESSSEPEPVVPRSTPRGSTSGKQKPHCRGMAPNGLPNHIMAPV ENSCPOP00000003466/1-919 FVLQVEAEDGAESEAPSEALSDPEPIVPRSTPRGSTSGKQKPHCRGMAPNGLPNYIMAPV XP_004839248.1/1-910 FVLQVEAEDGAESEVPSEGLSDPEPPVPRSTPRGSTSGKQKPHCRGVAPNGLPNYIMAPV *.****.** *** *** *:*** .*******.::*********:*******:***** ENSMUSP00000047210/1-950 WKCLHLTKDLREQHHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPE ENSRNOP00000057753/1-953 WKCLHLTKDLREQQHSFWEFAEWIPVAWKWQLLSELEAAPYLPQEEKSPLFSVQREGIPE ENSP00000352536/1-911 WKCLHLTKDFREQKHSYWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLPE ENSCPOP00000003466/1-919 WKCLHLTKDLREQMHSLWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLSE XP_004839248.1/1-910 WKCLHLTKDLREQKHSLWEFAEWIPLAWKWHLLSELEAAPYLPQEEKSPLFSVQREGLSE *********:*** ** ********:****:**************************:.* ENSMUSP00000047210/1-950 DGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETH ENSRNOP00000057753/1-953 DGTIYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETH ENSP00000352536/1-911 DGTLYRINRFSSITAHPERWDVSFFTGGPLWALDWCPVPEGAGASQYVALFSSPDMNETH ENSCPOP00000003466/1-919 DGTLYRINRFSSVTAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETH XP_004839248.1/1-910 DGTLYRINRFSSVTAHPERWDVSFFTGGPLWALDWCPVPEGSAASQYVALFSSPDMNETH ***:********:****************************:.***************** ENSMUSP00000047210/1-950 PLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDSGCIWDLKFCPSGAWEHPETL ENSRNOP00000057753/1-953 PLSQLHSGPGLLQLWHRGCIPSRSSSRSPSWLLPAVGGRRFEVWRVVFAPESSKPQPDSA ENSP00000352536/1-911 PLSQLHSGPGLLQLWGLGTLQQESCPGNRAHFVYGIACDNGCIWDLKFCPSGAWELPGTP ENSCPOP00000003466/1-919 PLSQLHSGPGLLQLWGLGTLQPESCSGNRAHFVYGIACDHGCIWDLKFCPSGAWELPGTL XP_004839248.1/1-910 PLSQLHSGPGLLQLWGLGTLQPESCSGNRAHFVYGIACDHGCIWDLKFCPSGAWELPSTL *************** * : .*.. . : :: .:. :* : *.*..: * : ENSMUSP00000047210/1-950 --RKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGS ENSRNOP00000057753/1-953 LTPQAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCLATLQVGS ENSP00000352536/1-911 --RKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAVKPAIYKVQCVATLQVGS ENSCPOP00000003466/1-919 --RKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCVATLQVGS XP_004839248.1/1-910 --RKAPLLPRLGLLALACSDGKVLLFSLPHPEALLAQQPPDAMKPAIYKVQCVATLQVGS :**************************************:*********:******* ENSMUSP00000047210/1-950 VQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYP ENSRNOP00000057753/1-953 VQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYP ENSP00000352536/1-911 MQATDPSECGQCLSLAWMPTRPHQHLAAGYYNGMVVFWNLPTNSPLQRIRLSDGSLKLYP ENSCPOP00000003466/1-919 MQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPTNSPLLRIRLSDGSLKLYP XP_004839248.1/1-910 VQASDPSECGQCLSLAWMPTRPHHHLAAGYYNGMVVFWNLPSNSPLLRIRLSDGSLKLYP :**:*******************:*****************:**** ************* ENSMUSP00000047210/1-950 FQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLL ENSRNOP00000057753/1-953 FQCFLAHDQAVRTIQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINCIKRFLSTELSWLL ENSP00000352536/1-911 FQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLL ENSCPOP00000003466/1-919 FQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLL XP_004839248.1/1-910 FQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSIKRFLSTELAWLL *************:********************************.*********:*** ENSMUSP00000047210/1-950 PYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDI ENSRNOP00000057753/1-953 PYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTVAAGDI ENSP00000352536/1-911 PYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDI ENSCPOP00000003466/1-919 PYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDI XP_004839248.1/1-910 PYNGVTVAQDNCYASYGLCGIHYIDAGYLGFKAYFTAPRKGTVWSLSGSDWLGTIAAGDI ******************************************************:***** ENSMUSP00000047210/1-950 SGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKAR ENSRNOP00000057753/1-953 SGELIAAILPDMASNPINVKKPAERRFPIYKADLIPYQDSPEDQDYSSTSSETPNPPKAR ENSP00000352536/1-911 SGELIAAILPDMALNPINVKRPVERRFPIYKADLIPYQDSPEGPDHSSASSGVPNPPKAR ENSCPOP00000003466/1-919 SGELIAAILPDMASNPINVKRPAERRFPIYKADLVPYQDSPEGQDLSSASSGIPDPPKAR XP_004839248.1/1-910 SGELIAAILPDMASNPINVKRPAERRFPVYKADLVPYQDNPEGQDHSSASSGAPDPPKAR ************* ******:*.*****:*****:****.**. * **:** *:***** ENSMUSP00000047210/1-950 TYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPN ENSRNOP00000057753/1-953 TYTETINHHYLLFQDTDLSSFHNLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPN ENSP00000352536/1-911 TYTETVNHHYLLFQDTDLGSFHDLLRREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPN ENSCPOP00000003466/1-919 TYAETVNHHYLLFQDTDLGSFHNLLHREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPN XP_004839248.1/1-910 TYAETVNHHYLLFQDTDLGSFHNLLHREPMLRMQEGEGHSQLCLDRLQLEAIHKVRFSPN **:**:************.***:**:********************************** ENSMUSP00000047210/1-950 LDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSH ENSRNOP00000057753/1-953 LDSYGWLVSGGQSGLVRIHFVRGLTSPLAHRVQLESRANFNAMFQPSFPTEGPGFSPSSH ENSP00000352536/1-911 LDSYGWLVSGGQSGLVRIHFVRGLASPLGHRMQLESRAHFNAMFQPSSPTRRPGFSPTSH ENSCPOP00000003466/1-919 LDSYGWLVSGGQSGLVRIHFIRGLTSPLGHRVQLESQAHFSAMFQPSSPTKGPGFPPASH XP_004839248.1/1-910 LDSYGWLVSGGQSGLVRIHFIRGLTSPLGHRMQLESQAHFSAMFQPSSPTKGPGFPPASH ********************:***:***.**:****:*:*.****** **. ***.*:** ENSMUSP00000047210/1-950 CLLPNP ENSRNOP00000057753/1-953 CLLPNP ENSP00000352536/1-911 RLLPTP ENSCPOP00000003466/1-919 RLLSSP XP_004839248.1/1-910 RLLSSP **..*