CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000048101/1-753 MAAAVGPLGDGELWQSWLPNHVVFLRLREGVRNQSPAEAEKPAASTSPSCPSLPPHLPTR ENSRNOP00000009015/1-742 MAAAAGPVGDGELWQSWLPNHVVFLRLREGLKNQSPAEADKPATSTSPSCPPLPPHLPTR ENSP00000458954/1-741 MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSP--PPQLLTR ENSCPOP00000003310/1-743 MAAVEGAISDSDLWQTWLPNHVVFSRLREGLKHQRSPETEDPASSSSSSSPPVPPQLLTK XP_004857389.1/1-743 MAAAEGPVGDNDLWQTWLPNHVVFLRLREGLKHQRPAEAEKPASSSLASSPPLPPQLLTR ***. *.:.*.:***:******** *****:::* ..*::.**:*: .*.* **:* *: ENSMUSP00000048101/1-753 NLVFGLGGELFLWDAEGSAFLVVRLRGPSGGGVEPPLSQYQRLLCINPPLFEIHQVLLSP ENSRNOP00000009015/1-742 NLVFGLGGELFLWDAEGSAFLVVRLRGPSGGSVEPPLSQYQRLLCINPPLFEIHQVLLSP ENSP00000458954/1-741 NVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSP ENSCPOP00000003310/1-743 NIVFGLGGELFLWDGEGSCFLVVRLRGLSSGSKQPSLSHYQKLLCINPPLFEIYQVLLSP XP_004857389.1/1-743 NLVFGLGGELFLWDGEGSCFLVVRLRGLSSGGEEPSLSRYQRLLCINPPLFEIYQVLLSP *:************.*.*.******** *.*. :*.**:**:***********:****** ENSMUSP00000048101/1-753 TQHHVALIGSKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAW ENSRNOP00000009015/1-742 TQHHVALIGTKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAW ENSP00000458954/1-741 TQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAW ENSCPOP00000003310/1-743 TQHHVALIGAKGLMVLELPKRWGKNSEFEGGKVTVNCSTTPIAERFFTSSTSLTLKHAAW XP_004857389.1/1-743 TQHHVALIGTKGLTVLELPKRWGKNSEFEGGKVTVNCSTTPVAERFFTSSTSLTLKHAAW ********* *** .****:****:******* ****** *:****************** ENSMUSP00000048101/1-753 YPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETA ENSRNOP00000009015/1-742 YPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETA ENSP00000458954/1-741 YPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETA ENSCPOP00000003310/1-743 YPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVILLSEAEEESLILHKGRAYTASLGETA XP_004857389.1/1-743 YPSEMLDPHIVLLTSDNVIRIYSLHEPQTPTKVILLSEAEEESLILNKGRAYTASLGETA ****:****:**************:******:**:*********:*:************* ENSMUSP00000048101/1-753 VAFDFGPLVTVSKNIFEQKDRD-VVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLP ENSRNOP00000009015/1-742 VAFDFGPLVTVSKNMFEQKDRE-AVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLP ENSP00000458954/1-741 VAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLP ENSCPOP00000003310/1-743 VAFDFGPLAAVPKNVFGQKGKDEVVASPLYILYENGETFLTYVSLLQSPGTIGKLLGPLP XP_004857389.1/1-743 VAFDFGPLAAIPKNIFGQKGKDEVVAYPLYILYENGETFLTYVSLLQSPGNIGKLLGPLP ********.::.*.:* *:.:: .** ***************:***:***.********* ENSMUSP00000048101/1-753 MHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTLEKSWDPRAD ENSRNOP00000009015/1-742 MHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEDDDQTLEKSWDPRAD ENSP00000458954/1-741 MHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRID ENSCPOP00000003310/1-743 MHPAAEDNYGYDACAILCLPCVPNILVITTESGMLYHCVVLEGEEEDEHTPEKSWDSRAE XP_004857389.1/1-743 MHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTPEKSWDSRPE ***************:************:****************:*::* *****.* : ENSMUSP00000048101/1-753 FIPSLYVFECVELELALKLASGEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGL ENSRNOP00000009015/1-742 LIPSLYVFECVELELALKLASAEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGL ENSP00000458954/1-741 LIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGL ENSCPOP00000003310/1-743 LIPSLYVFECVELELALKLASGEDDPFDCDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGL XP_004857389.1/1-743 LIPSLYVFECVELELALKLASGEDDPFDCDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGL :********************.***** .*****:**************:********** ENSMUSP00000048101/1-753 TWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGP ENSRNOP00000009015/1-742 TWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGP ENSP00000458954/1-741 TWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGP ENSCPOP00000003310/1-743 TWIHKLHKFLGSDEEDKDSLQELAAEQKCFVEHILCTKPLPCRQPAPIQGFWIVPDILGP XP_004857389.1/1-743 TWIHKLHKFLGSDEEDKDSLQELAAEQKCFVEHILCTKPLPCRQPAPIQGFWIVPDILGP ***********************::***********************:*********** ENSMUSP00000048101/1-753 TMICITSTYECLIRPLLSTVHPASPPLLCTQEDAEVAESPLRILAETPDSFEKHIKRILQ ENSRNOP00000009015/1-742 TMICITSTYECLIRPLLSTVHPASPPLLCTREDAGVAESPLRILAEAPDSFEKHIKRILQ ENSP00000458954/1-741 TMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQ ENSCPOP00000003310/1-743 TMICITSTYECLIRPLLSTVHPASPPLLCTQDDVEVTESPLRILAETPDSFEKHIRSILQ XP_004857389.1/1-743 TMICITSAYECLIRPLLSTVHPASPPLLCTQDDDEVAESPLRILAETPDSFEKHIRSILQ *******:***** ****************::* *:*****:***:********: *** ENSMUSP00000048101/1-753 RSAANPAFLKNCSARSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKL ENSRNOP00000009015/1-742 RSAANPALLK-----SSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKL ENSP00000458954/1-741 RSVANPAFLK-----ASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKL ENSCPOP00000003310/1-743 RTAANPAFLK-----SSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKL XP_004857389.1/1-743 RSAANPAFLK-----SSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKL *:.****:** :****:**********:**************************** ENSMUSP00000048101/1-753 LCDQKRKQLEDLNYCREERVSHLFRKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSF ENSRNOP00000009015/1-742 LCDQKRKQLEDLNYCREE------RKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSF ENSP00000458954/1-741 LCDQKKKQLEDLSYCREE------RKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSF ENSCPOP00000003310/1-743 LYDQKKKQLDDLNYCREE------RKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSF XP_004857389.1/1-743 LCDQKKKQLDDLNYCREE------RKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSF * ***:***:**.***** *******************************:**** ENSMUSP00000048101/1-753 HAQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLS ENSRNOP00000009015/1-742 HTQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLS ENSP00000458954/1-741 HSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILS ENSCPOP00000003310/1-743 HSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSPQKPTITLS XP_004857389.1/1-743 HSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSPQKPTITLS *::****************************************:******* **** ** ENSMUSP00000048101/1-753 AYQRKCIQSILKEEGEHIREMVKQINDIRNHVTF ENSRNOP00000009015/1-742 AYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF ENSP00000458954/1-741 AYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF ENSCPOP00000003310/1-743 AYQRKCIQSVLKEEGEHIREMVKQINDIRNHVNF XP_004857389.1/1-743 AYQRKCIQSVLKEEGEHIREMVKQINDIRNHVNF *********:**********************.*