CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000132078/1-1129 MKRGEKPEGYRQMRPKTFPASNYPGSSRQMLQEIRESLRNLSKPSDASKAEHNLNKMSTE ENSRNOP00000020098/1-1130 MKRGEKPEGYRQMRPKTFPASNYSGSSRQMLQEIRESLRNLSKPSDAAKAEHNLNKMSTE ENSP00000437550/1-1130 MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTE ENSCPOP00000003231/1-946 MKRSEKPEGYRQMRPKTFPASNYTGSSRQMLQEIRESLRNLSKPSDAAKAEHNMTKMSTE XP_004856952.1/1-939 MKRSEKPEGYRQMRPKTFPASNYTGSSRQMLQEIRESLRNLSKPSDAAKAEYNMTKMSTE ***.*******************. **********************:***:*:.***** ENSMUSP00000132078/1-1129 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETSSS-RSPSEVNPQMFQDLQAAGFDEDMV ENSRNOP00000020098/1-1130 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETSSS-RIPSEVNPQMFQDLQAAGFDEDMV ENSP00000437550/1-1130 DPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSS-RSTSEVNPQMLQDLQAAGFDEDMV ENSCPOP00000003231/1-946 DARQVRNPPKFGTYHKALQEIRNSLQPFANETSSSSRITSEVNPQMFQDLQAAGFDEDMV XP_004856952.1/1-939 DARQVRNPPKFGTYHKALQEIRNSLLPFANETSSSCRSTSEVNPQMFQDLQAAGFDEDMV *.***********:*********** ******.** * .*******:************* ENSMUSP00000132078/1-1129 IQALQKTNNRSIEAAVEFISKMSYQDPRREQMS-AAAARPINATMKPGNVQHSINRKQSW ENSRNOP00000020098/1-1130 IQALQKTNNRSIEAAVEFISKMSYQDPRREQMA-AAAARPINATMKPGNVQHSISRKQSW ENSP00000437550/1-1130 IQALQKTNNRSIEAAIEFISKMSYQDPRREQMA-AAAARPINASMKPGNVQQSVNRKQSW ENSCPOP00000003231/1-946 IQALQKTNNRSIEAAIEFISKMSYQDPRREQMATAAAARPINASMKPGSVQQSINRKQSW XP_004856952.1/1-939 IQALQKTNNRSIEAAIEFISKMSYQDPRREQMA-TAAPRPINASMKPGIVQQSINRKQSW ***************:****************: :**.*****:**** **:*:.***** ENSMUSP00000132078/1-1129 KGSKESLVPQRHGPSLGENVVYRSESPNSQADVGRPLSGSGIAAFAQAHPSNGQRVNPPP ENSRNOP00000020098/1-1130 KGSKESLVPQRHGPSLGENVVYRSESPNSQADVGRPLSGSGITAFAQAHPSNGQRVNPPP ENSP00000437550/1-1130 KGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPP ENSCPOP00000003231/1-946 KGSKESLVPQRHGPPLGESVAYCSESPNSQTDVGRPLSGSGITAFAQAHPNNGQRVNPPP XP_004856952.1/1-939 KGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGITAFAQAHPNNGQRVNPLP **************.***.*.* *******:***********:**.****.******* * ENSMUSP00000132078/1-1129 PPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPSSQTKRYSGNMEYVISRISPVPPGAWQE ENSRNOP00000020098/1-1130 PPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQE ENSP00000437550/1-1130 PPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQE ENSCPOP00000003231/1-946 PPQVRSVTP----------------PPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQE XP_004856952.1/1-939 PPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQE ********* *******.*************************** ENSMUSP00000132078/1-1129 GYPPPPLTTSPMNPPSQAQRAISSVPVGRQPIIMQSTSKFNFTPGRPGVQNGGGQSDFIV ENSRNOP00000020098/1-1130 GYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSTSKFNFTPGRPGVQNGGGQTDFIM ENSP00000437550/1-1130 GYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMI ENSCPOP00000003231/1-946 GYPPPPLNTSTMNPPNQGQRGISSVPVGRQPIIMQSSNKFNFTPGRPGIQNG-GQTDFMI XP_004856952.1/1-939 SYPPPPLNTSTMNPPNQGQRGISSVPVGRQPIIMQSSNKFNFTPGRSGIQNG-GQTDFMI .******.**.****.*.**.***************:.****..**.*:*** **:**:: ENSMUSP00000132078/1-1129 HQN-VPTGSVTRQPPPPYPLTPANGQSPSALQTGASAAPPSFANGNVPQSMMVPNRNSHN ENSRNOP00000020098/1-1130 HQNVVPTGAVNRQPPPPYPLTPANGQSPSALQAGGPAAPPSFSNGNVPPTMMVPNRNSHN ENSP00000437550/1-1130 HQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHN ENSCPOP00000003231/1-946 HQN-ISAGTVNRQPPPPYPLTPTNGQSPSTLQTVGSTAPSSYTNGSMPQSVMVPNRNSHN XP_004856952.1/1-939 HQNVVPAGTVNRQPPPPYPLTPTNGQSPSTLQTGGSTAPSSYTNGNVPQSMMVPNRNSHN *** :.:*:*.**********.:******:**: ..:**.*::**.:* ::********* ENSMUSP00000132078/1-1129 MELYNINVPGLQTAWPQSSSAPAQSSPSGGHEIPTWQPNIPVRSNSFNNPLGSRASHSAN ENSRNOP00000020098/1-1130 MELYNINVPGLQTTWPQSSSAPVQSSPSSGHEIPTWQPNIPVRSNSFNNPLGSRASHSAN ENSP00000437550/1-1130 MELYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSAN ENSCPOP00000003231/1-946 MELYNINIPGLQTTWPQSSSAPAQSSPSSGHEIPTWQPNMPVRSNSFNNPLGNRTSHSAN XP_004856952.1/1-939 MELYNINVPGLQTTWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRTSHSAN ******.:***** ********.*****.**********:************.*:***** ENSMUSP00000132078/1-1129 SQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWMPQPVQTVQPTPFSEGTAS ENSRNOP00000020098/1-1130 SQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWMPQPVQTVQPSPFSEGAAS ENSP00000437550/1-1130 SQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTAS ENSCPOP00000003231/1-946 SQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPVQTVQPSPFSEGTAS XP_004856952.1/1-939 SQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPVQTVQPSPFSEGTTS *****************************************:***:*****:**.**::* ENSMUSP00000132078/1-1129 SVPVIPPVAEAPSYQGPPPPYPKHLLHQNPSVPPYESVSKPCKDEQPSLPKEDDSEKSAD ENSRNOP00000020098/1-1130 NVPVIPPVAEAPSYQGPPPPYPKHLLHQTPSVPPYESASKPCKDDQPSSAKEEDSEKSLD ENSP00000437550/1-1130 NVTVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYE ENSCPOP00000003231/1-946 TVTVMPSVAEAPTYQGPPPPYPKHLLHQNSPVPPYESVNKSSKEDQSSLPKEDEDEKSFE XP_004856952.1/1-939 NMTVMPPVAEAPTYQGPPPPYPKHLLHQNPPVPPYESISKSSKEDQSSLPKEDEDEKNFE .:.*:*.*****.***************...****** .*..*::*.* .**::.**. : ENSMUSP00000132078/1-1129 SGDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRL ENSRNOP00000020098/1-1130 SVDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRL ENSP00000437550/1-1130 NVDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRL ENSCPOP00000003231/1-946 NVDSGDKEKKQITTSPITVRKNKRDEERRESRIQSYSPQAFKFYMEQHVENVLKSHQQRL XP_004856952.1/1-939 NVDNGDKEKKQITTSPITVRKNKRDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRL . *.*******************:*******************:**************** ENSMUSP00000132078/1-1129 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE ENSRNOP00000020098/1-1130 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE ENSP00000437550/1-1130 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE ENSCPOP00000003231/1-946 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE XP_004856952.1/1-939 HRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGE ************************************************************ ENSMUSP00000132078/1-1129 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL ENSRNOP00000020098/1-1130 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL ENSP00000437550/1-1130 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL ENSCPOP00000003231/1-946 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL XP_004856952.1/1-939 VCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNL ************************************************************ ENSMUSP00000132078/1-1129 YFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR ENSRNOP00000020098/1-1130 YFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR ENSP00000437550/1-1130 YFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR ENSCPOP00000003231/1-946 YFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR XP_004856952.1/1-939 YFVMDYIPGGDMMSLLIRMGIFPENLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDR ************************.*********************************** ENSMUSP00000132078/1-1129 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSNCRCGDRLKPLERRA ENSRNOP00000020098/1-1130 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSSEWGDPSNCRCGDRLKPLERRA ENSP00000437550/1-1130 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRA ENSCPOP00000003231/1-946 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSSEWGDPSNCRCGDRLKPLERRA XP_004856952.1/1-939 DGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWADPSNCRCGDRLKPLERRA **************************************.**.***.************** ENSMUSP00000132078/1-1129 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLET ENSRNOP00000020098/1-1130 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLET ENSP00000437550/1-1130 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLET ENSCPOP00000003231/1-946 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLET XP_004856952.1/1-939 ARQHQRCLAHSLVGTPNYIAPEVLLRTGYQ----------------------LANISSHS ***************************** **: . .: ENSMUSP00000132078/1-1129 QMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSD ENSRNOP00000020098/1-1130 QMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSD ENSP00000437550/1-1130 QMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSD ENSCPOP00000003231/1-946 QMKV-------------------------------------------------------- XP_004856952.1/1-939 TTS--------------------------------------------------------- . ENSMUSP00000132078/1-1129 LRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGSEEENISDTLNGWYKNGKHPEHAFYEF ENSRNOP00000020098/1-1130 LRQQSASYIPKITHPTDTSNFDPVDPDKLWSDGNEEENINDTLNGWYKNGKHPEHAFYEF ENSP00000437550/1-1130 LRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEF ENSCPOP00000003231/1-946 ------------------------------------------------------------ XP_004856952.1/1-939 ------------------------------------------------------------ ENSMUSP00000132078/1-1129 TFRRFFDDNGYPYNYPKPIEYEYIHSQGSEQQSDEDDQHTSSDGNNRDLVYV ENSRNOP00000020098/1-1130 TFRRFFDDNGYPYNYPKPIEYEYVSSQGSEQQSDEDDQHTGSDVNNRDLVYV ENSP00000437550/1-1130 TFRRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV ENSCPOP00000003231/1-946 ---------------------------------------------------- XP_004856952.1/1-939 ----------------------------------------------------