CLUSTAL W(1.81) multiple sequence alignment ENSRNOP00000056561/1-646 -----------------------------------CVLCSTVTTERPVQVKVVKVKKSDK ENSCPOP00000002905/1-900 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK ENSMUSP00000109121/1-901 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK ENSP00000370695/1-894 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK XP_004849757.1/1-894 MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKKNCFLCATVTTERPVQVKVVKVKKSDK *.**:******************** ENSRNOP00000056561/1-646 GDFYKRQIAWALRDLAVVDAKDAIKESPEFDLHFDKVYRWVASSIAEKNAFISCTWKLNQ ENSCPOP00000002905/1-900 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ ENSMUSP00000109121/1-901 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKVYKWVASSTAEKNAFISCIWKLNQ ENSP00000370695/1-894 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ XP_004849757.1/1-894 GDFYKRQIAWALRDLAVVDAKDAIKENPEFDLHFEKIYKWVASSTAEKNAFISCIWKLNQ **************************.*******:*:*:***** ********* ***** ENSRNOP00000056561/1-646 RYLRKKIDFLNVSSQLL-------EESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEI ENSCPOP00000002905/1-900 RYLRKKIDFVNVSSQLLEELPKVTEESVPSGENQSVTGGDEESVDEYQELNAREEQDIEI ENSMUSP00000109121/1-901 RYLRKKIDFVNVSSQLLEELPKVTEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEI ENSP00000370695/1-894 RYLRKKIDFVNVSSQLL-------EESVPSGENQSVTGGDEEVVDEYQELNAREEQDIEI XP_004849757.1/1-894 RYLRKKIDFVNVSSQLL-------EESVPSGENQSVTGGDEEAVDEYQELNAREEQDIEI *********:******* ************:***** ***************** ENSRNOP00000056561/1-646 MMEGCECAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMQLLDEALQEVDQIEL ENSCPOP00000002905/1-900 MMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEL ENSMUSP00000109121/1-901 MMEGCECAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNTLMQLLDEALTEVDQIEL ENSP00000370695/1-894 MMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEL XP_004849757.1/1-894 MMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEL ****** *********************************** **:****** ******* ENSRNOP00000056561/1-646 KLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHVKALQDG ENSCPOP00000002905/1-900 KLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQQG ENSMUSP00000109121/1-901 KLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEG ENSP00000370695/1-894 KLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEG XP_004849757.1/1-894 KLSSYEEMLQSVKEQMDQISESNHLIHLSNTNNVKLLSEIEFLVNHMDLAKGHIKALQEG *****************************************************:****:* ENSRNOP00000056561/1-646 DLASSRGIEACTNAADALLQCMNVALRPGHDMLLAIRQQQQRFSELREHFARRLASHLNN ENSCPOP00000002905/1-900 DLTSSHGIEACTNAADALLQCMNVALRPGHDMLLASAAQKQ-FSELRELFAKRLANHLNN ENSMUSP00000109121/1-901 DLVSSRGIEACTNAADALLQCMNVALRPGHDMLLAVKQQQQRFSDLREHFARRLASHLNN ENSP00000370695/1-894 DLASSRGIEACTNAADALLQCMNVALRPGHDLLLAVKQQQQRFSDLRELFARRLASHLNN XP_004849757.1/1-894 DLASSRGIEACTNAADALLQCMNVALRPGHDMLLAVKQQQQRFSDLREHFARRLASHLNN **.**:*************************:*** *:* **:*** **:***.**** ENSRNOP00000056561/1-646 VFVQQGHDQSSTLAQHSAELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY ENSCPOP00000002905/1-900 VFVQQGHDQSSNLAQHSIELTLPNHHPLHRDLLRYAKLMEWLKSTDYAIYEGLTRNYMDY ENSMUSP00000109121/1-901 VFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY ENSP00000370695/1-894 VFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY XP_004849757.1/1-894 VFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKSTDYGKYEGLTKNYMDY ***********.***** *********:*******************. *****:***** ENSRNOP00000056561/1-646 LSRLYEREIKDFFEVAKMKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSS ENSCPOP00000002905/1-900 LSRLYEREIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSS ENSMUSP00000109121/1-901 LSRLYEREIKDFFEVAKMKMTGTSKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSS ENSP00000370695/1-894 LSRLYEREIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSS XP_004849757.1/1-894 LSRLYEREIKDFFEVAKIKMTGTTKESKKFATLPRKESAVKQETESLHGSSGKLTGSTSS *****************:*****:************************************ ENSRNOP00000056561/1-646 LNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFI ENSCPOP00000002905/1-900 LNKLSVQSSGNRRSQSSSLLDMGNMSTSDLDVADRTKFDKIFEQVLSELEPLCLAEQDFI ENSMUSP00000109121/1-901 LNKLSVQSSGSRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFI ENSP00000370695/1-894 LNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFI XP_004849757.1/1-894 LNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFI **********.***************:********************************* ENSRNOP00000056561/1-646 SKFFKLQQHQNLSASMAEAEDLDGGSLSRPQSSGSLLPVSSEKDMIRQMMIKIFRCIEPE ENSCPOP00000002905/1-900 SKFFKLQQHQSMSGTMTEAEDLDGVTLSRQHNSGTPLPVSSERDMIRQMMIKIFRCIEPD ENSMUSP00000109121/1-901 SKFFKLQQHQNMSASMTEAEDLDGGSLLRQHSSGTLLPVSSEKDMIRQMMIKIFRCIEPE ENSP00000370695/1-894 SKFFKLQQHQSMPGTMAEAEDLDGGTLSRQHNCGTPLPVSSEKDMIRQMMIKIFRCIEPE XP_004849757.1/1-894 SKFFKLQQHQSISGTMTEAEDLDGGTLSRQHNSGTPLPVSSERDMIRQMMIKIFRCIEPE **********.:..:*:******* :* * :..*: ******:****************: ENSRNOP00000056561/1-646 LNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCIS- ENSCPOP00000002905/1-900 LSSLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISN ENSMUSP00000109121/1-901 LNNLIALGDKVDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISN ENSP00000370695/1-894 LNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISN XP_004849757.1/1-894 LNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISN *..*******:************************************************ ENSRNOP00000056561/1-646 ------------------------------------------------------------ ENSCPOP00000002905/1-900 QIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNV ENSMUSP00000109121/1-901 QIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFINV ENSP00000370695/1-894 QIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNV XP_004849757.1/1-894 QIRQMEEVKISKKSKVGILPFVAEFEEFAGLAESIFKNAERRGDLDKAYTKLIRGVFVNV ENSRNOP00000056561/1-646 ------------------------------------------------------------ ENSCPOP00000002905/1-900 EKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQ ENSMUSP00000109121/1-901 EKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQ ENSP00000370695/1-894 EKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQ XP_004849757.1/1-894 EKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKQKYTDHLQSYVIYSLGQ ENSRNOP00000056561/1-646 ------------------------------------------------------------ ENSCPOP00000002905/1-900 PLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVD ENSMUSP00000109121/1-901 PLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVD ENSP00000370695/1-894 PLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVD XP_004849757.1/1-894 PLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVD ENSRNOP00000056561/1-646 ---CEPESIAH--WNREDAE----------------SGDSCCL----------SDPLGSS ENSCPOP00000002905/1-900 KHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQS ENSMUSP00000109121/1-901 KHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQS ENSP00000370695/1-894 KHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGVTMEFTIQDILDYCSSIAQS XP_004849757.1/1-894 KHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQS ** *.: : *: : * .*.. : ...:..* ENSRNOP00000056561/1-646 - ENSCPOP00000002905/1-900 H ENSMUSP00000109121/1-901 H ENSP00000370695/1-894 H XP_004849757.1/1-894 H