CLUSTAL W(1.81) multiple sequence alignment ENSP00000268704/1-795 MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL ENSMUSP00000119552/1-781 MAAALLLLRGLRPGPEPRPRRLWGLLSGRGPGLSSGAGARRPYAARGTPVGPAAAGGHAP ENSRNOP00000048848/1-744 MAAALLLLRALRQSPEPGPWRLWAQLSGRSPGLFSGAGGRRPYVVRGTPIGLAAAGGHTP ENSCPOP00000002810/1-789 MAAMLLLLRVLRQGPGPGPGRLWGPGS----NLSFGPASRRPYVVCRPSLGVAGTGSQVL XP_004842697.1/1-787 MAAVLLLLRILRQGPGPGPGRLWGLGS----GLFFGPAS-RPYVVCRPPLGVAGAGGRAL **. ***** ** .* * * **. . .: .. *** . .. . * :*.:. ENSP00000268704/1-795 Q--SLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKG ENSMUSP00000119552/1-781 Q--SLLLRILTPSFEGISGLLLKQHIVPNAVRLWPLSGVTLYFNTSRMKQKNKDNDKPKG ENSRNOP00000048848/1-744 Q--SLLLRILTPSFEGVSGLLLKRHIVPSAIRLWQLSGSTLYFNTSGLKQKNKDDDKPKG ENSCPOP00000002810/1-789 Q--SLQLRMLTPAFKGPGGLLLKQHLVQNPAGLWRLLGGAYYFTTSRMKQKNKDSDESKG XP_004842697.1/1-787 QVKSLQSRMLTPAFEGIAGLLLKQYLIQNPVGLWRLLGGTYYFTTSRMRQKNKDNDKSKG * ** *:***:*:* *****:::: .. ** * * : **.** ::****:.*:.** ENSP00000268704/1-795 KAPEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKG ENSMUSP00000119552/1-781 KTPEDDEEEKRRKEREDQMYRERLRTLFIIALVMSLLNSLSTSGGSISWADFVNEMLAKG ENSRNOP00000048848/1-744 KAPEDDEEERRRKEREDQMYRERLRTLFIIAIVMSLLNSLSTSGGSISWADFVNEMLAKG ENSCPOP00000002810/1-789 KAPGNDEEERRRREREDQMYRERLRTLFVIAVVLSLLNSLSSSGGNISWNDFVSEMLAKG XP_004842697.1/1-787 KAPGDDEEERQRKEREDQMYRERLRTLLVIAVVMSLLNSLSSSGGNISWNDFVSEMLAKG *:* :****::*:**:***********::**:*:****:**:***.*** *** ****** ENSP00000268704/1-795 EVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAK ENSMUSP00000119552/1-781 EVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESK ENSRNOP00000048848/1-744 EVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIESK ENSCPOP00000002810/1-789 EVQRVQVVPESDVVEVYLHPGAVVFGRPRLALVYRMQVANIDKFEEKLRAAEDELNIESK XP_004842697.1/1-787 EVQRVQVVPESDVVEVYLHPGAVVFGRPRLSLVYRMQVANIDKFEEKLRAAEDELNIESK ******************************:*:*************************:* ENSP00000268704/1-795 DRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIV ENSMUSP00000119552/1-781 DRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIV ENSRNOP00000048848/1-744 DRIPVSYKRTGFFGNALYALGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIV ENSCPOP00000002810/1-789 DRIPVSYRRTGFFGNALYALGMTAVGLAILWYMFRLAGMAGREGGFSALNQLKMARFTMV XP_004842697.1/1-787 DRIPVSYKRTGFFGNALYALGMTAVGLAILWYMFRLAGMTGREGGFSAFNQLKMARFTMV *******:**********::************:******:********:*********:* ENSP00000268704/1-795 DGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLL ENSMUSP00000119552/1-781 DGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLL ENSRNOP00000048848/1-744 DGKTGKGVSFQDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLL ENSCPOP00000002810/1-789 DGKSGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLL XP_004842697.1/1-787 DGKSGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLL *** ******:************************************************* ENSP00000268704/1-795 AKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRS ENSMUSP00000119552/1-781 AKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRS ENSRNOP00000048848/1-744 AKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRS ENSCPOP00000002810/1-789 VKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRS XP_004842697.1/1-787 AKAVATEAQVPFLAMAGPEFVEVVGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRS .**********************:************************************ ENSP00000268704/1-795 TTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFID ENSMUSP00000119552/1-781 TSMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADVLDNALMRPGRLDRHVFID ENSRNOP00000048848/1-744 TSMSGFSNTEEEQTLNQLLVEMDGMGTADHVIVLASTNRADVLDNALMRPGRLDRHVFID ENSCPOP00000002810/1-789 TSISGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDSALMRPGRLDRHVFID XP_004842697.1/1-787 TSKSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDSALMRPGRLDRHVFID *: ************************:*************:**.*************** ENSP00000268704/1-795 LPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHT ENSMUSP00000119552/1-781 LPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFSGADIANICNEAALHAAREGHT ENSRNOP00000048848/1-744 LPTLQERREIFEQHLKGLKLTQPSSFYSQRLAELTPGFS--------------------- ENSCPOP00000002810/1-789 LPTLQERREIFEQHLKGLKLTQDSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHS XP_004842697.1/1-787 LPTLQERREIFEQHLKGLKLTQESRFYSQRLAELTPGFSGADIANICNEAALHAAREGHS ****************.***** * ************** ENSP00000268704/1-795 SVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITP ENSMUSP00000119552/1-781 SVHTFNFEYAVERVIAGTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAP ENSRNOP00000048848/1-744 ----------------GTAKKSKILSKEEQRVVAFHESGHALVGWLLEHTEAVMKVSIAP ENSCPOP00000002810/1-789 SVHTQDFEYAVERVVAGTAKKSKVLSREEQKVVAFHESGHALVGWLLEHTEAVMKVSIAP XP_004842697.1/1-787 SVHTLDFEYAVERVVAGTAKKSKVLSREEQRAVAFHESGHALVGWLLEHTEAVMKVSIAP *******:**:***:.*************:************:* ENSP00000268704/1-795 RTNAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIA ENSMUSP00000119552/1-781 RTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIA ENSRNOP00000048848/1-744 RTNAALGFSQMLPRDQYLFTKEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIA ENSCPOP00000002810/1-789 RTNAALGFSQMLPRDQRLFTTEELFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTHIA XP_004842697.1/1-787 RTNAALGFSQMLPRDQHLFTTEQLFERMCMALGGRAAEAISFSRVTSGAQDDLRKVTRIA ********:******* ***.*:*************:**:**..*************:** ENSP00000268704/1-795 YSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVL ENSMUSP00000119552/1-781 YSMVKQFGMAPSIGPVSFPEAQEGLMGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVL ENSRNOP00000048848/1-744 YSMVKQFGMAPSIGPVSFPEAQEGLVGIGRRPFSQGLQQMMDHEARLLVARAYRHTEKVL ENSCPOP00000002810/1-789 YSMVKQFGMAPAVGPVSFPEAQEGPVGIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVL XP_004842697.1/1-787 YSMVKQFGMVPSIGPVSFPEAQEGLMDIGRRPFSQGLQQMMDHEAKLLVAKAYRHTEKVL *********.*.:**:******** :.******************:****:********* ENSP00000268704/1-795 QDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEET ENSMUSP00000119552/1-781 LDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKERQASGEEE- ENSRNOP00000048848/1-744 LDNLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAEKEKQASGEEE- ENSCPOP00000002810/1-789 LGNLDKLQMLANALLEKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAQRENQVTGEEEA XP_004842697.1/1-787 LDNLDKLQALANALLQKEVINYEDIEALIGPPPHGPKKMIAPQKWIDAQSESQEAGEEEA .****** ******:***************************:****: * * **** ENSP00000268704/1-795 EETQQPPLGGEEPTWPK ENSMUSP00000119552/1-781 --APAP----------- ENSRNOP00000048848/1-744 --APAP----------- ENSCPOP00000002810/1-789 --APPPPPRGEEPSWPG XP_004842697.1/1-787 --APLPPLHGEELS--- : *