CLUSTAL W(1.81) multiple sequence alignment ENSP00000339637/1-821 ---------------------------------------------MDPECAQLLPALCAV ENSMUSP00000098074/1-867 MVHFALSGLIPVAEGCGGGIRTPRLTRSRRERTSYPDLGGTACLIMDPECSRLLPALCAV ENSRNOP00000059762/1-822 ---------------------------------------------MDAECSRLLPALCAV ENSCPOP00000002591/1-825 ---------------------------------------------MDPECSRLLPALCAV XP_004840472.1/1-825 ---------------------------------------------MDPECSRLLPAFCSV **.**::****:*:* ENSP00000339637/1-821 LVDPRQPVADDTCLEKLLDWFKTVTEGESSVVLLQEHPCLVELLSHV--LKVQDLSSGVL ENSMUSP00000098074/1-867 LADPRQLVADDTCLEKLLDWFKTVTEAESSLQLLQDHPCLMELLSHV--LKPQDVSPRVL ENSRNOP00000059762/1-822 LADPRQLVADDTCLEKLLDWFKTVTEAEPSLQLLQDHPCLMELLSHV--LKPQDVSPRVL ENSCPOP00000002591/1-825 LADPSQAVADDTCLEKLLDWFKTVTEAGSSLLLLQENPCLVDLLSHVLDLKPQDVSPRVL XP_004840472.1/1-825 LVDPRQAVADDTCLEKLLDWFKTVTEAGSSLLLLQENPCLVDLLSHVLDLKPQDVSPRVL *.** * *******************. .*: ***::***::***** ** **:*. ** ENSP00000339637/1-821 SFSLRLAGTFAAQENCFQYLQQGELLPGLFGEPGPLGRATWAVPTVRSGWIQGLRSLAQH ENSMUSP00000098074/1-867 SFALRLVGVFAAQEDCFEYLQQGELLLGLFGESGAPGWAAWSIPSVRSGWIQGLCYLAHH ENSRNOP00000059762/1-822 SFALRLVGVFAAQEDCFQYLQQGELLLGLFGETGALSWAAWSIPSVRSGWIQGLCSLAHH ENSCPOP00000002591/1-825 SFSLCLAGTFAAQEDCFEYLQQGQLLLGLFGEAGPLSWAAWSVPTVRSGWIRGLRSLAQH XP_004840472.1/1-825 SFSLRLAGMFAAQEDCFEYLQQGQLLLGLFGEAGPLSWAVWSVPTVRSGWIQGLKSLAQH **:* *.* *****:**:*****:** *****.*. . *.*::*:******:** **:* ENSP00000339637/1-821 PSALRFLADHGAVDTIFSLQGDSSLFVASAASQLLVHVLALSMRGGAEGQPCLPGGDWPA ENSMUSP00000098074/1-867 PSALHFLADSGAVDTLFSLQGDPSLFVASAASQLLVHILALSMQGGAPGSPVPEAAAWPM ENSRNOP00000059762/1-822 PSALHFLADSGAVDTIFSLQGDPSLFVASAASQLLVHILALSMQGGAPGSPVPEAVAWPV ENSCPOP00000002591/1-825 PSGLHFLGNSGAVDALFSLQGDSSLFVASAASQLLVHVLALSMQGKAAGSPSSQGNAWPA XP_004840472.1/1-825 PGGLHFLGDSGAVDALFSLQGDSSLFVASAASQLLVHVLALSMQDKAEGSPSLKGSAWPA *..*:**.: ****::******.**************:*****:. * *.* . ** ENSP00000339637/1-821 CAQKIMDHVEESLCSAATPKVTQALNVLTTTFGRCQSPWTEALWVRLSPRVACLLERDPI ENSMUSP00000098074/1-867 CAQKIVNHVDESLHAKATPQVTQALNVLTTTFGRCHNPWTGVLWERLSPPVARLFERDPI ENSRNOP00000059762/1-822 CAQKIMNHVEESLHSKATPQVTQALNVLTTTFGRCHNPWTGVLWERLSPPVARLFERDPI ENSCPOP00000002591/1-825 CAQKIVDHVEACLCSTAAPQVTQALNVLTTTFGRCHSPWTEVLWGQLSPLVAHLLESDPI XP_004840472.1/1-825 CAQKIVAHVEASLCSTTALQITQALNVLTTTFGRCHSPWTEVLWGQLSPLVAHLLDSEPV *****: **: .* : :: ::**************:.*** .** :*** ** *:: :*: ENSP00000339637/1-821 PAAHSFVDLLLCVARSPVFSSSDGSLWETVARALSCLGPTHMGPLALGILKLEHCPQALR ENSMUSP00000098074/1-867 PAVHALMDLLLSVARSPVLNFAACGLWEMLAQTLSRLSPIQAGPLALGTLKLQHCPQELR ENSRNOP00000059762/1-822 PATHSLMDLLLSVARSPVLNFAACGLWEMLAQTLSRLSPTQAGPLALGTLKLQHCPQELR ENSCPOP00000002591/1-825 PAAHSLVDLLLSVARSPVFASADCGLWETMARMLSCLSPTQAGSLALGILKLQHCPQALR XP_004840472.1/1-825 PATHSLVDLLLSVARSPVFASADCTLWETIARMLSCLSPMQTGPLALGTLKLQHCPQALR **.*:::****.******: : *** :*: ** *.* : *.**** ***:**** ** ENSP00000339637/1-821 TQAFQVLLQPLACVLKATVQAPGPPGLLDGT-ADDATTVDTLLASKSSCAGLLCRTLAHL ENSMUSP00000098074/1-867 TQAFGVLLQPLACILKATTQAPGPPGLLDGT-VGSLLTVDILLASKSACVGLLCQTLAHL ENSRNOP00000059762/1-822 TQAFRVLLQPLACILKATTQAPGPPGLLDGT-AGSLLTVDALLSSKSACVGLLCQTLAHL ENSCPOP00000002591/1-825 SQAFRVLLQPLVCILRATTQAPGPPGLLDETSAGSSMMVDTLLSSKSACVGLLCQTLAHL XP_004840472.1/1-825 SQAFGVLLQPLACILRATAQAPGPPGLLDETTQGCSMTVDTLLSSKSACVGLLCQTLAHL :*** ******.*:*:**.********** * . ** **:***:*.****:***** ENSP00000339637/1-821 EELQPLPQRPSPWPQASLLGATVTVLRLCDGSAAPASSVGGHLCGTLAGCVRVQRAALDF ENSMUSP00000098074/1-867 EELQMLPQCPSPWPQVHLLQAALTILHLCDGSADPSSSAGGRLCGTLGGCVRVQRAALDF ENSRNOP00000059762/1-822 EELQMLPQCPSPWPQVPLLQAAVTILRLSDGSADPSSSAGGRLCGALGGCVRVQRAALDF ENSCPOP00000002591/1-825 EELQPLPQRPSPWPQTLLVEAAVIILQLCDGSAVPSSSEGGRLCGALAGCSRVQRAALDF XP_004840472.1/1-825 EELQPLPQHPLPWPQTLLVEAVVIILRLCDGSAAPSSSEGCRLCGTLAGCIRVQRAALGF **** *** * ****. *: *.: :*:*.**** *:** * :***:*.** *******.* ENSP00000339637/1-821 LGTLSQGTGPQELVTQALAVLLECLESPGSSPTVLKKAFQATLRWLLSSPKTPGCSDLGP ENSMUSP00000098074/1-867 LGTLSQGTSPLELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQNPHKTPSSSDLSS ENSRNOP00000059762/1-822 LGTLSLGTSPLELVLEVFAVLLKTLESPESSPMVLKKAFQATLRWLQSPHKTPSGSDLSP ENSCPOP00000002591/1-825 LGTLSQGISSRELMPQVFAVLLETLESPASSPMVLKKAFQATLRWLLDLPSPSSCLDLGP XP_004840472.1/1-825 LGTLTLGTSSWELVPQVFAILLETLKSPASSPTVLKKAFQAVLHWLLDSPTPPGCSDLGP ****: * .. **: :.:*:**: *:** *** ********.*:** . .... **.. ENSP00000339637/1-821 LIPQFLRELFPVLQKRLCHPCWEVRDSALEFLTQLSRHWGGQADFRCALLASEVPQLALQ ENSMUSP00000098074/1-867 DALLFLGELFPILQKRLCSPCWEVRDSALEFLTHLIRHWGGQADFREALRSSEVPTLALQ ENSRNOP00000059762/1-822 DALLFLGELFPILQKRLCSPCWEVRDSALEFLTHLIRDWGGQADFREALHSSEVPTLARQ ENSCPOP00000002591/1-825 HAPLFLRELFPVLQKRLCSPCWEVRDSALEFLTHLTACWGGEADFREALLASEVPKLTWQ XP_004840472.1/1-825 HTPLFLRELFPVLQKHLCSPCWEVRDSALEFLTHLSMCWGGEANFREVLLASDVPKLAWQ ** ****:***:** **************:* ***:*:** .* :*:** *: * ENSP00000339637/1-821 LLQDPESYVRASAVTAMGQLSSQGLHA-PTSPEHAEARQSLFLELLHILSVDSEGFPRRA ENSMUSP00000098074/1-867 LLQDPESYVRASAVGAAGQLSSQGLQAAPASPENSQAQQGLLMDLMHILSTDSEGFPRRA ENSRNOP00000059762/1-822 LLQDPESYVRASAVGAAGQLSSQGLQATPANQQELSNLQGLLMDLMHILSTDSEGFPRRA ENSCPOP00000002591/1-825 LLRDPESYVRASAVTAMGQLSSQGLEAVSESPGHPEVQQGLIGELLHILSMDSEGFPRRA XP_004840472.1/1-825 LLRDPESYVRASAVTAMGQLSSQGLQAASDSPGHPEVQQGLVGELLHILSVDSEGFPRRA **:*********** * ********.* . . . . *.*. :*:**** ********* ENSP00000339637/1-821 VMQVFTEWLRDGHADAAQDTEQFVATVLQAASRDLDWEVRAQGLELALVFLGQTLGPPRT ENSMUSP00000098074/1-867 VLRVFTDWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELARVFLTQALGQPSL ENSRNOP00000059762/1-822 VLRVFTEWLRDGHADVVRDTEWFVATVLQAVSRDLDWEVRVQGLELAQVFLIQAMGQPRL ENSCPOP00000002591/1-825 VVRVFTEWLRDSHADVARDTEWFVATVLQMVSQDLDWEVRAQGLELVRVFLVQTLGQPNP XP_004840472.1/1-825 VTRVFTEWLRNSHADVVQDTEWFVATVLQMVSRDLDWEVRAQGLELVQVFLAQTLGQPNP * :***:***:.***..:*** ******* .*:*******.*****. *** *::* * ENSP00000339637/1-821 HCPYAVALPEVAPAQPLTEALRALCHVGLFDFAFCALFDCDRPVAQKSCDLLLFLRDKIA ENSMUSP00000098074/1-867 HCPYTVGLPRASSPRPHPEFLQTLCRLPLFEFAFCALLDCDRPVAQKACDLLLFLRDKTV ENSRNOP00000059762/1-822 HCPYTVGLPGATSSRPHLEFLQTLCRLPLFEFAFCALLDCDRPVAQKACDLLLFLRDKTV ENSCPOP00000002591/1-825 HCPYAVTLPKVTPPGPLPEVLRTLCQLQIIDFAFRALFDCDRPVAQKACDLLLFLREKTA XP_004840472.1/1-825 SCPYAVALPKVTPPSPLPEVLRTLCQMQIFDFAFRALFDCDRPVAQKACDLLLFLRNKSA ***:* ** .:.. * * *::**:: :::*** **:*********:********:* . ENSP00000339637/1-821 SYSSLREARGSPNTASAEATLPRWRAGEQAQPPGDQEPEAVLAMLRSLDLEGLRSTLAES ENSMUSP00000098074/1-867 PCSSPREAGDSPNSASVEAALQRWREGEQAQPLGDLDPEAMLAILRALDLEGLQGRLAKS ENSRNOP00000059762/1-822 SCSNPQEAGDSPNSASVEAALQRWREGEQAQPLGDLEPEAMLAILRSLDLEGLQGRLAKS ENSCPOP00000002591/1-825 PCSGLQEPGNSSDVTSVEATLHRWQAGEQSQPLGNLEPEELLAALRSLDLEGFQGRLAES XP_004840472.1/1-825 PCSGLQEAGDSSDVASVEATLERWQVGEQGQPLGSLEPEVVLAALRSMDLEGLQSRLAES . *. :*. .*.: :*.**:* **: ***.** *. :** :** **::****::. **:* ENSP00000339637/1-821 SDHVEKSPQSLLQDMLATGGFLQGDEADCY ENSMUSP00000098074/1-867 SDHVEKSPQSLLQDMLATVGVLEENEADCY ENSRNOP00000059762/1-822 SDHVEKSPQSLLQDMLATVGVLEENEADCY ENSCPOP00000002591/1-825 SDHVEKSPQSLLQDMLATVAVLEENVADCY XP_004840472.1/1-825 SDHVEKSPQSLLQDVLATVALLEENVADCY **************:*** ..*: : ****