CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000002266/1-1306 -----------------------------VQGQVHPTLESNDDALQY-EELILQLLNMLC ENSP00000387784/1-1333 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC XP_004839393.1/1-1318 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC ENSMUSP00000067786/1-1319 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC ENSRNOP00000009359/1-1319 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNEDALQYVEELILQLLNMLC ************:***** ************ ENSCPOP00000002266/1-1306 -AQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY ENSP00000387784/1-1333 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY XP_004839393.1/1-1318 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY ENSMUSP00000067786/1-1319 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY ENSRNOP00000009359/1-1319 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY *********************************************.*:** **:***** ENSCPOP00000002266/1-1306 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV ENSP00000387784/1-1333 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV XP_004839393.1/1-1318 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV ENSMUSP00000067786/1-1319 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV ENSRNOP00000009359/1-1319 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV ************************************************************ ENSCPOP00000002266/1-1306 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN ENSP00000387784/1-1333 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN XP_004839393.1/1-1318 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN ENSMUSP00000067786/1-1319 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSN ENSRNOP00000009359/1-1319 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSY **********************************************************: ENSCPOP00000002266/1-1306 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR ENSP00000387784/1-1333 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR XP_004839393.1/1-1318 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR ENSMUSP00000067786/1-1319 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR ENSRNOP00000009359/1-1319 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR ************************************************************ ENSCPOP00000002266/1-1306 DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL ENSP00000387784/1-1333 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL XP_004839393.1/1-1318 DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL ENSMUSP00000067786/1-1319 DILRPGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL ENSRNOP00000009359/1-1319 DVLRPGFHERFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL *:****** :************************************************** ENSCPOP00000002266/1-1306 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK ENSP00000387784/1-1333 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK XP_004839393.1/1-1318 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK ENSMUSP00000067786/1-1319 EEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK ENSRNOP00000009359/1-1319 EEKSEDQEDKECMKQAITALLNVQSGMEKICSKNLAKRRLSESACRFYSQQMKGKQLAIK ************:********************.************************** ENSCPOP00000002266/1-1306 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL ENSP00000387784/1-1333 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL XP_004839393.1/1-1318 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL ENSMUSP00000067786/1-1319 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL ENSRNOP00000009359/1-1319 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL ************************************************************ ENSCPOP00000002266/1-1306 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA ENSP00000387784/1-1333 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA XP_004839393.1/1-1318 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA ENSMUSP00000067786/1-1319 PGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA ENSRNOP00000009359/1-1319 PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA ****.**********************.************ ******************* ENSCPOP00000002266/1-1306 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSAEVYRFAEPDSEENIIFEENVQPKAGIPI ENSP00000387784/1-1333 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI XP_004839393.1/1-1318 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSAEVYRFAEPDSEENIIFEENMQPKAGIPI ENSMUSP00000067786/1-1319 LISLQYRSTLERMLDVTVLQEEKEEQMRLPSAEVYRFAEPDSEENILFEENVQPKAGIPI ENSRNOP00000009359/1-1319 LISLQYRSTLERMLDVTMLQEEKEEHMRLPSADVYRFAEPDSEENILFEENVQPKAGIPI *****************:*******:******:*************:****:******** ENSCPOP00000002266/1-1306 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR ENSP00000387784/1-1333 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR XP_004839393.1/1-1318 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR ENSMUSP00000067786/1-1319 IKAGTVLKLIERLTYHMYADPNFVRTFLTTYRSFCRPQELLSLLIERFEIPEPEPTEADR ENSRNOP00000009359/1-1319 IKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLNLLIERFEIPEPEPTEADR ******:****************************:*****.*:**************** ENSCPOP00000002266/1-1306 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT ENSP00000387784/1-1333 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT XP_004839393.1/1-1318 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLQRMEEFIGT ENSMUSP00000067786/1-1319 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT ENSRNOP00000009359/1-1319 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDVDLLQRMEEFIGT ***********************************************. *********** ENSCPOP00000002266/1-1306 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHTETFDLLTLH ENSP00000387784/1-1333 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH XP_004839393.1/1-1318 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHTETFDLLTLH ENSMUSP00000067786/1-1319 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH ENSRNOP00000009359/1-1319 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQNSPPTVEWHISRPGHIETFDLLTLH ***********************************.************** ********* ENSCPOP00000002266/1-1306 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ENSP00000387784/1-1333 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV XP_004839393.1/1-1318 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ENSMUSP00000067786/1-1319 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ENSRNOP00000009359/1-1319 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ************************************************************ ENSCPOP00000002266/1-1306 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQRKI ENSP00000387784/1-1333 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI XP_004839393.1/1-1318 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI ENSMUSP00000067786/1-1319 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI ENSRNOP00000009359/1-1319 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI *********************************************************:** ENSCPOP00000002266/1-1306 LEEAHELSEDHYKKYLAKLRSINPPCVPFFEYFLTRISSKPSNFNKPNVLPKKHDQTMVP ENSP00000387784/1-1333 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE--GNPEVL-KRHGKELIN XP_004839393.1/1-1318 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE--GNPEVL-KRHGKELIN ENSMUSP00000067786/1-1319 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE--GNPEVL-RRHGKELIN ENSRNOP00000009359/1-1319 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEE--GNPEVL-RRHGKELIN ****************************** :**.* .. . .:*:** ::*.: :: ENSCPOP00000002266/1-1306 FRRKKKKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEI ENSP00000387784/1-1333 F-SKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEI XP_004839393.1/1-1318 F-SKRRKVAEITGEIQQYQNQPYCLRVESDIKKFFENLNPMGNSMEKEFTDYLFNKSLEI ENSMUSP00000067786/1-1319 F-SKRRRVAEITGEIQQYQNQPYCLRVEPDIKRFFENLNPMGNSMEKEFTDYLFNKSLEI ENSRNOP00000009359/1-1319 F-SKRRRVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEI * *:::*********************.***:*************************** ENSCPOP00000002266/1-1306 EPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETEST ENSP00000387784/1-1333 EPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETEST XP_004839393.1/1-1318 EPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETEST ENSMUSP00000067786/1-1319 EPRHPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETEST ENSRNOP00000009359/1-1319 EPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETEST ***:******************************************************** ENSCPOP00000002266/1-1306 ASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHS-SPFHSSSDTVFIQVTLPHGPRSASV ENSP00000387784/1-1333 ASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHS-SPFHSSNDTVFIQVTLPHGPRSASV XP_004839393.1/1-1318 ASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHS-SPFHS---------------RSASV ENSMUSP00000067786/1-1319 ASAPNSPRTPLTPPPASGTSSNTDVCSVFDSDHSASPFHS---------------RSASV ENSRNOP00000009359/1-1319 ASAPNSPRTPLTPPPASSASSNTDVCSVFDSDHSASPFHS---------------RSASV *****************.:**.************ ***** ***** ENSCPOP00000002266/1-1306 SSISLTKSTDDVPIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR ENSP00000387784/1-1333 SSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR XP_004839393.1/1-1318 SSISLTKGTDEVPIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR ENSMUSP00000067786/1-1319 SSISLSKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR ENSRNOP00000009359/1-1319 SSISLSKGTEEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR *****:*.*::**:********************************************** ENSCPOP00000002266/1-1306 YSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSP ENSP00000387784/1-1333 YSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSP XP_004839393.1/1-1318 YSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSP ENSMUSP00000067786/1-1319 YSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSP ENSRNOP00000009359/1-1319 YSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSP *************************************************.********** ENSCPOP00000002266/1-1306 FTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIVGPPVPPRQSTSQHIPKLPPKTYKREHT ENSP00000387784/1-1333 FTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHT XP_004839393.1/1-1318 FTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHT ENSMUSP00000067786/1-1319 FTPPPPQTPSPHGTRRHLPSPPLTQEMDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHT ENSRNOP00000009359/1-1319 FTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHT **************************:*****.************ ************** ENSCPOP00000002266/1-1306 HPSMHRDGPPLLENAHSS ENSP00000387784/1-1333 HPSMHRDGPPLLENAHSS XP_004839393.1/1-1318 HPSMHRDGPPLLENAHSS ENSMUSP00000067786/1-1319 HPSMHRDGPPLLENAHSS ENSRNOP00000009359/1-1319 HPSMHRDGPPLLENAHSS ******************