CLUSTAL W(1.81) multiple sequence alignment ENSRNOP00000066554/1-881 MASENSPLLAYRLLGEEGAAFPPNGAGGSGVASARKLSTFLGVVVPTVLSMFSIVVFLRI ENSP00000275730/1-914 MASESSPLLAYRLLGEEGVALPANGAGGPGGASARKLSTFLGVVVPTVLSMFSIVVFLRI ENSMUSP00000038106/1-914 MASESSPLLAYRLLGEEGAAFPPNGAGVSGVPSSRKLSTFLGVVVPTVLSMFSIVVFLRI XP_004840227.1/1-917 MASESSPLLAYRLLGEEGAGFQANGAGGPGGAPARKLSTFLGVVVPTVLSMFSIVVFLRI ENSCPOP00000001566/1-915 MASESSPLLAYRLLGEEGAALPTSGAGGSGGAPARKLSTFLGVVVPTVLSMFSIVVFLRI ****.*************..: ..*** .* ..:************************** ENSRNOP00000066554/1-881 GFVVGHAGLLQALAMLLVAYVILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSI ENSP00000275730/1-914 GFVVGHAGLLQALAMLLVAYFILALTVLSVCAIATNGAVQGGGAYFMISRTLGPEVGGSI ENSMUSP00000038106/1-914 GFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSI XP_004840227.1/1-917 GFVVGHAGLLQALAMLLVAYIILVLTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSI ENSCPOP00000001566/1-915 GFVVGHAGLLQALAMLLVAYIILALTVLSVCAIATNGAVRGGGAYFMISRTLGPEVGGSI ********************.**.***************:******************** ENSRNOP00000066554/1-881 GLMFYLANVCGCAVSLLGLVESILDVFGADVTGSSGIKVLPQGYGWNLLYGSLLLGLVGG ENSP00000275730/1-914 GLMFYLANVCGCAVSLLGLVESVLDVFGADATGPSGLRVLPQGYGWNLLYGSLLLGLVGG ENSMUSP00000038106/1-914 GLMFYLANVCGCAVSLLGLVESILDVFGADATGSSGIQVLPQGYGWNLLYGSLLLGLVGG XP_004840227.1/1-917 GLMFYLANVCGCAVSLLGLVEAVLDVFGADAMGSSGLRVLPQGYGWNLLYGSLLLGLVGG ENSCPOP00000001566/1-915 GLMFYLANVCGCAVSLLGLVEAVLDVFGADPTGSSGLQVLPQGYGWNLLYGSLLLGLVGG *********************::******* *.**::********************** ENSRNOP00000066554/1-881 VCALGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNITLAPRPGTNGSSVPPRHGHFT ENSP00000275730/1-914 VCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIRLTPRPGPNGSSLPPRFGHFT ENSMUSP00000038106/1-914 VCTLGAGLYARASFLTFLLVSGSLASVLVSFVAVGPRNIPLAPRPGTNASSVPHRHGHFT XP_004840227.1/1-917 VCTLGAGLYARASFLTFLLVSGSLASVLISFVAVGPRDIPLAPRPGTNVSSLRTRFGHFT ENSCPOP00000001566/1-915 VCTLGAGLYARASFLTFLLVSGSLASVLISFVAVVPKNIPLAPRPGANGSSLPTRFGHFT **:*************************:***** *::* *:****.* **: *.**** ENSRNOP00000066554/1-881 GFNGSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPL ENSP00000275730/1-914 GFNSSTLKDNLGAGYAEDYTTGAVMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPL ENSMUSP00000038106/1-914 GFNGSTLRDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPL XP_004840227.1/1-917 GFNISTLKDNLGAGYAEDYTTGAMMNFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPL ENSCPOP00000001566/1-915 GFNTSTLKDNLGAGYAEDYTTGAMMTFASVFAVLFNGCTGIMAGANMSGELKDPSRAIPL *** ***:***************:*.********************************** ENSRNOP00000066554/1-881 GTIIAVAYTFFIYILLFFLSSFTCDRALLQGDYGFFRDISLWPPLVLIGIYATALSASMS ENSP00000275730/1-914 GTIVAVAYTFFVYVLLFFLSSFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATALSASMS ENSMUSP00000038106/1-914 GTIIAVAYTFFIYILLFFLSSFTCDRALLQEDYGFFRDISLWPPLVLIGIYATALSASMS XP_004840227.1/1-917 GTIIAVAYTFFIYILLFFLSGFTCDRTLLQEDYGFFRAISLWPPLVLIGIYATSLSASMS ENSCPOP00000001566/1-915 GTIIAVAYTFFIYILLFFLSSFTCDRTLLQENYGFFRAISLWPPLVLIGIYATSLSASMS ***:*******:*:******.*****:*** :***** ***************:****** ENSRNOP00000066554/1-881 SLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAV ENSP00000275730/1-914 SLIGASRILHALARDDLFGVILAPAKVVSRGGNPWAAVLYSWGLVQLVLLAGKLNTLAAV ENSMUSP00000038106/1-914 SLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAV XP_004840227.1/1-917 SLIGASRILHALAQDNLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAV ENSCPOP00000001566/1-915 SLIGASRILHALAQDDLFGVILAPAKVVSGGGNPWGAVLYSWGLVQLVLLAGKLNTLAAV *************:*:************* *****.************************ ENSRNOP00000066554/1-881 VTVFYLVAYAAVDLSCLSLEWASAPNFRPGRLLGPWHTCSPTMYN-MMMMVVVVVGGGGG ENSP00000275730/1-914 VTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGG ENSMUSP00000038106/1-914 VTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGG XP_004840227.1/1-917 VTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGG ENSCPOP00000001566/1-915 VTVFYLVAYAAVDLSCLSLEWASAPNFRPTFSLFSWHTCLLGVASCLLMMFLISPGAAGG ***************************** * .**** : . ::**.:: *..** ENSRNOP00000066554/1-881 VLMVMMVMMVMMVMMVVLVMVVVVMVMVMMVVMVVMVMMVMMIKVETRYWEPQHLGGTGQ ENSP00000275730/1-914 SLLLMGLLAALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGN ENSMUSP00000038106/1-914 SLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKEHVKFWRPQLLLLVGN XP_004840227.1/1-917 SLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGN ENSCPOP00000001566/1-915 SLLLMGLLSALLTARGGPSSWGYVSQALLFHQVRKYLLRLDVRKDHVKFWRPQLLLLVGN *::* :: .::. * ::: : :: : : * ..::*.** * .*: ENSRNOP00000066554/1-881 PDGEL-------------LNRLGWILSAGITGMSY-------------------HILADL ENSP00000275730/1-914 PRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDRAQVKAFVDL ENSMUSP00000038106/1-914 PRGALPLLRLANQLKKGGLYVLGHVTLGDLDSLPSDPVQPQYGAWLSLVDLAQVKAFVDL XP_004840227.1/1-917 PRGALPLLRLANQLKKGGLYVLGHVTLGDLDALPSDPVQPQYGAWLSLVDQAQVKAFVDL ENSCPOP00000001566/1-915 PRGALPLLRLANQLKKGGLYVLGHVTLGDLDMLPSDPVQPQYGAWLSLVDRAQVKAFVDL * * * * ** : ..: :. : :.** ENSRNOP00000066554/1-881 SVSGRVLCGVNSVLSLMPLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSP ENSP00000275730/1-914 TLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPADSTREGSSP ENSMUSP00000038106/1-914 TLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFSEPAEGTREGGSP XP_004840227.1/1-917 TLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFMEPSDVTQEGVSP ENSCPOP00000001566/1-915 TLSPSVRQGAQHLLRISGLGGMKPNTLVLGFYDDAPPQDHFLTDPAFMEPADGTQEGGSP ::* * *.: :* : ***************************** **:: *:** ** ENSRNOP00000066554/1-881 ALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSGSSAQ ENSP00000275730/1-914 ALSTLFPPPRAPGSPRALNPQDYVATVADALKMNKNVVLARASGALPPERLSRGSGGTSQ ENSMUSP00000038106/1-914 ALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLSRGSSSSAQ XP_004840227.1/1-917 ALSTLFPPPRAPGSPRALSPQDYVATMADALKMNKNVVLARACGALPPERLSRGSGTTSQ ENSCPOP00000001566/1-915 ALSTLFPPPRAPGSPRALSPQDYVATVADALKMNKNVVLARACGALPPERLNRGSGSASQ ******************.*******:***************.********.***. ::* ENSRNOP00000066554/1-881 LHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGA ENSP00000275730/1-914 LHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGA ENSMUSP00000038106/1-914 LHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILSMVPAWHSARLRIFLCLGPREAPGA XP_004840227.1/1-917 LHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPQEAPGA ENSCPOP00000001566/1-915 LHHVDVWPLNLLRPRGGPGYVDVCGLFLLQMATILGMVPAWHSARLRIFLCLGPREAPGA ***********************************.******************:***** ENSRNOP00000066554/1-881 AEGRLRALLSQLRIRAEVQEVVWGEGAEAGEP---EEEEGDFVNGGRGDEEAEALACSAN ENSP00000275730/1-914 AEGRLRALLSQLRIRAEVQEVVWGEGAGAGEP--EAEEEGDFVNSGRGDAEAEALARSAN ENSMUSP00000038106/1-914 AEGRLRALLSQLRIRAEVQEVVWGEGAETGEP---EEEEGDFVNGGRGDEEAEALACSAN XP_004840227.1/1-917 AEGRLRALLSQLRIRAEVQEVVWGEGAAAGEPGEEEEEEGDFVNGGRGDAEAEALACSAN ENSCPOP00000001566/1-915 AEGRLRALLSQLRIRAEVHEVVWGEGAGAGEQ--EEEEEGDFVNGGRGDAEAEALACSAN ******************:******** :** ********.**** ****** *** ENSRNOP00000066554/1-881 ALVRAQQGRGTGGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDL ENSP00000275730/1-914 ALVRAQQGRGTGGGPGGPEGGDA-EGPITALTFLYLPRPPADPARYPRYLALLETLTRDL ENSMUSP00000038106/1-914 ALVRAQQGRGTVGGPGGPEGRDGEEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDL XP_004840227.1/1-917 ALVRAQQGRGTGGGPGGPEARDGDEGPTTALTFLYLPRPPADPARYPRYLALLETLSRDL ENSCPOP00000001566/1-915 TLVRAQQGRGTGGGPGGPKGRDGDEGPITALTFLYLPRPPADPARYPRYLALLETLSQDL :********** ******:. *. *** ****************************::** ENSRNOP00000066554/1-881 GPTLLIHGVTPVTCTDL ENSP00000275730/1-914 GPTLLVHGVTPVTCTDL ENSMUSP00000038106/1-914 GPTLLIHGVTPVTCTDL XP_004840227.1/1-917 GPTLLIHGVTPVTCTDL ENSCPOP00000001566/1-915 GPTLLIHGVTPVTCTDL *****:***********