CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000036110/1-866 MKMENYEACVGFDVCEIPLSAVAQKIMSAMRSGDFMDSRNEGESTNTSKVAKKSSVHYSV ENSRNOP00000034638/1-862 MKMENYEACVGFDLCETPLSTVAQKIMSAMRSGDLMASRNEGERTKTSEVTKKPSVHFSV ENSP00000435506/1-900 --MENYEALVGFDLCNTPLSSVAQKIMSAMHSGDLVDSKTWGKSTETMEVINKSSVKYSV ENSCPOP00000001501/1-861 --MENYGTCVGFDLCETPLSSVAQKILSAMHSGDAVDSENLGENTKTVEVTNKCNVKYPV XP_004847453.1/1-931 MKMENYEACVGFELCETPLSSVAQKIMSAMHSGDLVDSKNWGESTKTVDVTNKSSARYSV **** : ***::*: ***:*****:***:*** : *.. *: *:* .* :* ..::.* ENSMUSP00000036110/1-866 LAEHEETQSLGTKNPESLITQTPRGSIELCPQPSITKLTCQLSAGQVQNSISSLGLSSYL ENSRNOP00000034638/1-862 LAEHEKTQPLETKNPKSLINQTPRGSVELSSQPSITK----LSAGQVQNSISSSGLSSYL ENSP00000435506/1-900 QLEDRKTQSPEKKDLKSLRSQTSRGSAKLSPQSFSVRLTDQLSADQKQKSISSLTLSSCL ENSCPOP00000001501/1-861 LLEDRKDQSLEERNPKSLISQASRGSIRPSSQSSRAKLTGQLPADQQQKSISSWPLSSGL XP_004847453.1/1-931 LLEGGRDRSLEGRNPKSLTSQASRGSIRLSPQSSRARLRGQLSADQKQKSISPLALSSYL * . :. :: :** .*:.*** . ..*. .: *.*.* *:***. *** * ENSMUSP00000036110/1-866 IPQCDQEASVLPNMEHKRQHFLKENIGKEDKDNSSLKRKYITCSKSSEKASKHTALEKDT ENSRNOP00000034638/1-862 IPQCDQEASVLQNREHKRKHFLKENIGKEDKDSLNLKRKYITCSNSPEKASKHTALGKET ENSP00000435506/1-900 IPQYNQEASVLQKKGHKRKHFLMENINNENKGSINLKRKHITYNNLSEKTSKQMALEEDT ENSCPOP00000001501/1-861 ILQYNQEVSGLQKTKNKRKYFLEGTINKENKEGMKIKRKHVTYGNSSEKTSKHMALEEDA XP_004847453.1/1-931 IPQYNEEASVLQRTENKRKHFLKEITNKENKESMNLKRKCVTYGNLSEKASKHLASEEEA * * ::*.* * . :**::** .:*:* . .:*** :* .: .**:**: * ::: ENSMUSP00000036110/1-866 DGTESWPNSRDTRALGERLCDVRYLGDLAKAQLMDALKQAAALVVTLMYKDGSTQLSAK- ENSRNOP00000034638/1-862 DGTESWQNSEDTRALGKQLCDVRYLGDLAKVQLMDVLKQAAALVVTLMYKDGSTQLSAK- ENSP00000435506/1-900 DDAEGYLNSGNSGALKKHFCDIRHLDDWAKSQLIEMLKQAAALVITVMYTDGSTQLGAD- ENSCPOP00000001501/1-861 NKVETHLISGSSG----HFCDIRYLDDLAKGQLTEALKQAAALVLTLMYKDGSTQLGADQ XP_004847453.1/1-931 NKVEAYLTSGDSG----HICDIRYLDDLAKSQLTEALKQTAALVVTLMYKDGSTQLRAD- : .* * .: ::**:*:*.* ** ** : ***:****:*:**.****** *. ENSMUSP00000036110/1-866 -EALTCTVKGIVVLLKSHV--GNSTLTLPAHGGALEKDFISEDHCVYIHTEHSPFWDPKQ ENSRNOP00000034638/1-862 -QALTCPVKGIVVLLKSHV--GSSPLILPAHGGALGKDFTSTDHCIYIHTEQSPFWDPKQ ENSP00000435506/1-900 -QTPVSSVRGIVVLVKRQAEGGHGCPDAPAC-GPVLEGFVSDDPCIYIQIEHSAIWDQEQ ENSCPOP00000001501/1-861 SQALTSCVKGVVMLLKSHVEAGSGLLDGLACAGGLAGESGQEDWCIYIHMERTCLWGREQ XP_004847453.1/1-931 -QAPTSCVRGIVMLLKSQVEAGSSW--------SLAEGFKQEDRCIYIHTEHACLRGQEQ :: .. *:*:*:*:* :. * . : . * *:**: *:: : . :* ENSMUSP00000036110/1-866 EAHSLFVRNILFWTLRCKCPVVCFNAKDFVRTVLQLYGEDGSWKHVADFVGLDPRVAAWL ENSRNOP00000034638/1-862 EAHSLFVRNILFWTLRCKCPVVCFNAKDFVRTVLQLYGEDGSWKHVAGFVGLDPRVAAWL ENSP00000435506/1-900 EAHQQFARNVLFQTMKCKCPVICFNAKDFVRIVLQFFGNDGSWKHVADFIGLDPRIAAWL ENSCPOP00000001501/1-861 EAHRLFARNVLFQTLTCKCPVICFNAKEFVKTVLQFFGDDSSWRHVANFVGLDPRIAAWL XP_004847453.1/1-931 EAHRIFARNVLFQTLKCKCPVICFNAKDFVRTVLQFFDDDGSWRHVADFVGLDPRIAAWL *** *.**:** *: *****:*****:**: ***::.:*.**:***.*:*****:**** ENSMUSP00000036110/1-866 IDPSDTAPSFEDLVAKHLEKSITVKPSSTFREASRNTLSQNVFMNLKILYDLTMDLCSKL ENSRNOP00000034638/1-862 IDPSDTAPSFEDLVAKHLEKSIIVKPSSTFNDASINIVSQNVCVNLKILYDLTMDLCSKL ENSP00000435506/1-900 IDPSDATPSFEDLVEKYCEKSITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKL ENSCPOP00000001501/1-861 IDPSDAVPSFEDLVAKHHEKSSTVKVSSTCGNSSRNCVNQNVRVNLNILYRLTMDLCSKL XP_004847453.1/1-931 IDPSDTAPSFEDLVAKHLEKSVTVEVSSTYGNSSRNNVYQNVRVNLSILYRLTKDLCSKL *****:.******* *: *** *: .** ::* * : *** **. ** ** ****** ENSMUSP00000036110/1-866 KAYGLWQLFCTLELPLIPILAVMENHKIPVDKEEMERTSALLGARLKELEQEAHFVAGEQ ENSRNOP00000034638/1-862 KAYGLWQLFCTLELPLIPILAVMENHKISIDKEEMERTSALLGAHLKKLEQEAHFVAGEQ ENSP00000435506/1-900 KDYGLWQLFRTLELPLIPILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGER ENSCPOP00000001501/1-861 KANGLWQLFCTLELPLVPVLAVMENNKIQVNREEMERMSVLLGARLKELEQEAHFVAGEQ XP_004847453.1/1-931 KANGLWQLFCTLELPLIPVLAVMENHKIQVNKEEMERISALLGAHLKKLEQEAHFVAGEQ * ****** ******:*:*****.: * :::****: *.****:**:***********: ENSMUSP00000036110/1-866 FLIMSNNQLREILFGKLKLHLLSQRKHLPRTGLQNQLSTSEAMLNSLQDLHPLPKLILEY ENSRNOP00000034638/1-862 FLIMSNNQLREILFGKLKLHLLSQRKHLPRTGLQNQLSTSEAMLNSLQDLHPLPKIILEY ENSP00000435506/1-900 FLITSNNQLREILFGKLKLHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEY ENSCPOP00000001501/1-861 FLIMSNNQLRKILFGKLKLHLLNPRKTLPRPGTQRHPSTSEAVLNSLQDLHPLPKIILEY XP_004847453.1/1-931 FLIMSNNQLREILFGKLKLHLLGPRKSLPGPGLQQYPSTSEAVLNSLQDLHPLPKIILEY *** ******:***********. *: ** .* *. *****:**:*:*******:**** ENSMUSP00000036110/1-866 RQVHKIKSTFIDGLLAYMK---KGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIKISKP ENSRNOP00000034638/1-862 RQVHKIKSTFIDGLLAYMK---KGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIQISRP ENSP00000435506/1-900 RQVHKIKSTFVDGLLACMK---KGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIQITTP ENSCPOP00000001501/1-861 RQVHKIKSTFVDGLLACMKKLIKGSISSTWNQTGTVTGRLSAKHPNIQGISKQPIQITTP XP_004847453.1/1-931 RQVHKTKSTFVDGLLACMK---QGSISSTWNQTGTVTGRLSAKHPNIQGISKQPIQITTP ***** ****:***** ** :*****************************:**:*: * ENSMUSP00000036110/1-866 WNFKGKEEETVTISPRTLFVSSEGHTFLAADFSQIELRILAHLSGDPELLKLFQESERDD ENSRNOP00000034638/1-862 RNFKGKEEETATISPRTLFVSSEGYTFLAADFSQIELRILAHLSGDPELLKLFQESERDD ENSP00000435506/1-900 KNFKGKEDKILTISPRAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDD ENSCPOP00000001501/1-861 QKFQGKEDKILMISPRDLFVSSKGHTFLAADFSQIELRILAHLSGDPELLKLFQESERDD XP_004847453.1/1-931 PIFKGEEDKALTISPRALFVSSQGHTFLAADFSQIELRILAHLSGDPELLKLFQESERDD *:*:*:: **** :****:*:***************:******************* ENSMUSP00000036110/1-866 VFSTLTSQWKDIPIERVTHMDREQTKKVVYSVVYGAGKERLAACLGVTVLEATHFLERFL ENSRNOP00000034638/1-862 VFSTLTSQWKDIPIERVTHMDREQTKKVVYSVVYGAGKERLAACLGVTVLEATHFLEQFL ENSP00000435506/1-900 VFSTLTSQWKDVPVEQVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFL ENSCPOP00000001501/1-861 VFSTLTSQWKNIPVEHVTPVHREQTKKVVYSVVYGAGKERLATCLGVTVQEATQFLESFL XP_004847453.1/1-931 VFSTLTSQWKNISIEHVTPADREQTKKVVYSVVYGAGKERLAACLGVTVQEATQFLESFL **********::.:*:** .*********:***********:****.: **::*** ** ENSMUSP00000036110/1-866 QKYKKIKDFAQTVIGQCHSAGYVTSILGRRRPLPRICAQDQQLRAQAERQAVNFVVQGSA ENSRNOP00000034638/1-862 QKYKKIKDFAQTVIGQCHSAGYVASILGRRRPLPRICAQNQQLRAQAERQAVNFVVQGSA ENSP00000435506/1-900 QKYKKIKDFARAAIAQCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSA ENSCPOP00000001501/1-861 QKYKKIKDFAQAAIAQCHQKGYVASIMGRRRPLPRIHTQDPQLRAQAERQAVNFMVQGSA XP_004847453.1/1-931 QKYKKIKDFAQATIAQCHRTGYVASILGRRRPLPRIHARNPELRAQAERQAVNFVVQGSA **********::.*.*** * *.**:********* ::: :************:***** ENSMUSP00000036110/1-866 ADLCKLAMIRISTAVATSPTLTARLVAQIHDELLFEVEDTQVPEFAALVRRIMESLQQVQ ENSRNOP00000034638/1-862 ADLCKLAMIRIFAAVATSPTLTARLVAQIHDELLFEVEDTQIPEFAALVRRIMESLQQVQ ENSP00000435506/1-900 ADLCKLAMIHVFTAVAASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQ ENSCPOP00000001501/1-861 ADLCKMAMIRIFTAIATSSTLTARLTAQIHDELLFEVEDSQVPEFAVLVRDTMESLQHHW XP_004847453.1/1-931 ADLCKMAMIRIFAAVTTSTTLTARLVAQIHDELLFEVEDSQVPEFAVLVRRAMESLQRLW *****:***:: :*:::* ******.*************.*:** *.*** ****:: ENSMUSP00000036110/1-866 TLELQLQVPLKVNLSVGRSWGHLTPLQEILGSA--------------------------- ENSRNOP00000034638/1-862 TLELQLQVPLKVNLSIGRSWGHLTPLQETLGSA--------------------------- ENSP00000435506/1-900 ALELQLQVPLKVSLSAGRSWGHLVPLQEAWGPPPGPCR-TESPSNSLAAPGSPASTQPPP ENSCPOP00000001501/1-861 SPELQLQVPLKVSLSTGRSWGCLAPLQ--------------------------------- XP_004847453.1/1-931 SPELQLQVPLKVSLSAGRSWGCLAPLQEALPRGSSESHESESPGCDGCPPPGLLSTYPRP : **********.** ***** *.*** ENSMUSP00000036110/1-866 ------------------------------------------------ ENSRNOP00000034638/1-862 ------------------------------------------------ ENSP00000435506/1-900 LHFSPSFCL--------------------------------------- ENSCPOP00000001501/1-861 ------------------------------------------------ XP_004847453.1/1-931 VHFSPSFLSVAPGNSGRRELASTSPLCGLSRSPRTVWELQEGHRAGSA