CLUSTAL W(1.81) multiple sequence alignment ENSRNOP00000061906/1-1417 MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL ENSMUSP00000082971/1-1405 MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL ENSCPOP00000001011/1-1442 MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL ENSP00000385216/1-1441 MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL XP_004839504.1/1-1393 MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL ************************************************************ ENSRNOP00000061906/1-1417 SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL ENSMUSP00000082971/1-1405 SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL ENSCPOP00000001011/1-1442 SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL ENSP00000385216/1-1441 SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL XP_004839504.1/1-1393 SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL ************************************************************ ENSRNOP00000061906/1-1417 DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSL--- ENSMUSP00000082971/1-1405 DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG ENSCPOP00000001011/1-1442 DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG ENSP00000385216/1-1441 DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG XP_004839504.1/1-1393 DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG ********************************************************* ENSRNOP00000061906/1-1417 ---------------------------GTENQEACQRYEVMQCFTVSQPKSIQEDGE--- ENSMUSP00000082971/1-1405 VPWPQEATRRNSHTFNCRMLIHPPEDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ ENSCPOP00000001011/1-1442 VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ ENSP00000385216/1-1441 VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ XP_004839504.1/1-1393 VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ ****************************** ENSRNOP00000061906/1-1417 -----------------------------GKIISIDTSSLRAAGRTGWEDLVRKCIYAFF ENSMUSP00000082971/1-1405 SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF ENSCPOP00000001011/1-1442 SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF ENSP00000385216/1-1441 SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF XP_004839504.1/1-1393 SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF ******************************* ENSRNOP00000061906/1-1417 QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG ENSMUSP00000082971/1-1405 QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG ENSCPOP00000001011/1-1442 QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG ENSP00000385216/1-1441 QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG XP_004839504.1/1-1393 QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG ************************************************************ ENSRNOP00000061906/1-1417 IHIIDREHSGLSPQDDTNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARANR ENSMUSP00000082971/1-1405 IHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNR ENSCPOP00000001011/1-1442 IHIIDREHSGLSPQDDTNSGMSMSRVNPSVNPSISPAHGVARPPTLPPSNSNMVSARVNR ENSP00000385216/1-1441 IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR XP_004839504.1/1-1393 IHIIDREHSGLSPQDDTNSGMSIPRINPSVNPSISPAHGVARSSTLPPSNSNMVSTRVNR ****************:*****:.*:******.*******:*..******.****:* ** ENSRNOP00000061906/1-1417 QQSTDLNSGSSHSNSSSSQGSFGCSPGNQIVASVALSQGQAGSQSSNPSLNLNNSPMEGT ENSMUSP00000082971/1-1405 QQSSDLNSSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGT ENSCPOP00000001011/1-1442 QQSSDLHSSSSHTNAGNNQGSFGCSPGNQIVANVALNQGQASSQSSNPSLNLNNSAMEGT ENSP00000385216/1-1441 QQSSDLHS-SSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGT XP_004839504.1/1-1393 QQSSDLHSSSSHTNSSNNQGSFGCSSGNQIVANVALSQGQASSQSSNPSLSLNNSAMEGT ***:**:* ***:*:...**.****.*.****.***.****.********.****.**** ENSRNOP00000061906/1-1417 GISLAQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACSNNNRSYSNIPVT ENSMUSP00000082971/1-1405 GIALSQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVT ENSCPOP00000001011/1-1442 GISLTQFMSPRRQVTSGLAARGRVPNNSFPPNIPTLNSPVGMTSGACSNSNRSYSNIPVP ENSP00000385216/1-1441 GISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVT XP_004839504.1/1-1393 GISLTQFMSPRRQVPSGLATRARMSNNSFPPNIPTLNSPVGMTSSGCNNSNRSYSNIPVT **:*:********. ****:* *:.********.**.****:**..*.*.*********. ENSRNOP00000061906/1-1417 SLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDNKEIASILNEMIQ-- ENSMUSP00000082971/1-1405 SLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKEIASILNEMIQSD ENSCPOP00000001011/1-1442 SLQGMNEGPSNSVGFSASSPVLRQMGSQNSPSRLSLQPAKTESKDNKEIASILNEMIQ-- ENSP00000385216/1-1441 SLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQ-- XP_004839504.1/1-1393 SLQGMSEGPSNSVGFSANSPVLRQMSSQNSPSRLNLQPAKAESKDNKEIASILNEMIQ-- *****.***.*******.*******.********.:****:****.************ ENSRNOP00000061906/1-1417 -SDNSANEGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKD ENSMUSP00000082971/1-1405 NSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKD ENSCPOP00000001011/1-1442 -SDNSSSDGKPLDSGLLHSNDRLSDGDSKYAQTSHKLVQLLTTTAEQQLRHADIDASCKD ENSP00000385216/1-1441 -SDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKD XP_004839504.1/1-1393 -SDNSSGDGKPLDSGLLHNNDRLADGDSKYAQTSHKLVQLLTTTAEQQLRHADIDTSCKD ****:.:**********.****::*****:************************:**** ENSRNOP00000061906/1-1417 VLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSAS ENSMUSP00000082971/1-1405 VLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVP ENSCPOP00000001011/1-1442 VLSCTGASNSASANSSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDT-- ENSP00000385216/1-1441 VLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDS-- XP_004839504.1/1-1393 VLSCTGTSNSASANSSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVESDKKDS-- ******:*.***:*.***:*********************************.:***: ENSRNOP00000061906/1-1417 ASTAMSVSGQAQGSASIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVK ENSMUSP00000082971/1-1405 ASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYLLDKDEKDLRSTPNLCLDDVKVK ENSCPOP00000001011/1-1442 AAASVSAAGQAQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVK ENSP00000385216/1-1441 ASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVK XP_004839504.1/1-1393 ASTSVSVTGQAQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVK *::::*.:** **.:********:****************************.******* ENSRNOP00000061906/1-1417 VEKKEQMDPCNTNPAPVTKPAPEEVKLESQSQFSADLDQFDQLLPTLEKAAQLPGLCETD ENSMUSP00000082971/1-1405 VEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLDQFDQLLPTLEKAAQLPSLCETD ENSCPOP00000001011/1-1442 VEKKEQMDPCTTNSTPVSKPAPEEIKLESQSQFAADLDQFDQLLPPLEKAAQLPGLCETD ENSP00000385216/1-1441 VEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETD XP_004839504.1/1-1393 VEKKEQMDPCNTNPTPVTKPAPEEIKLESQSQFTADLDQFDQLLPTLEKAAQLPGLCETD **********.**.:*::**:***:***:****:***********.********.***** ENSRNOP00000061906/1-1417 RMDGAVPGVNIKSEILPASLQPTPARSAPRLNRLPELELEAIDNQFGQPGAGDQIPWANN ENSMUSP00000082971/1-1405 RMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANN ENSCPOP00000001011/1-1442 RMEGAATSVTIKSESLPASLQPTTARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWANN ENSP00000385216/1-1441 RMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNN XP_004839504.1/1-1393 RMDGAATSVTIKSEILPASLQSSTARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWANN **:**...*.**:* ******.:.**.:.**.******************:******:** ENSRNOP00000061906/1-1417 TVTAINQSKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRA ENSMUSP00000082971/1-1405 TLTTINQNKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRA ENSCPOP00000001011/1-1442 AVTAVNQTKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRA ENSP00000385216/1-1441 TVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRA XP_004839504.1/1-1393 AVTAVNQTKPEE------------------------------YGFFSNK----------- ::*::**.*.*: .*:*.* ENSRNOP00000061906/1-1417 LGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYPQPYSSPSPTAGLSGPFQGMVRQ ENSMUSP00000082971/1-1405 LGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGLSGPFQGMVRQ ENSCPOP00000001011/1-1442 LGIDKLVQGGGLDVLSERFPPQQATPPLMMEERPSLYPQPYNSPSPTASLPSPFQGMVRQ ENSP00000385216/1-1441 LGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQ XP_004839504.1/1-1393 --------GGGLDVLSERFPPQQATPPLMMEERPNLYPQPYSSPSPTASLPSPFQGMVRQ ********************:**:**.**.***.******.*..******** ENSRNOP00000061906/1-1417 KPSLGTMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQ ENSMUSP00000082971/1-1405 KPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQ ENSCPOP00000001011/1-1442 KPSLGTMPVQVTPPRGTFSPGIGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQ ENSP00000385216/1-1441 KPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQ XP_004839504.1/1-1393 KPSLGTMPVQVTPPRGAFSPGIGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQ *****:**********:***.:********************************:***** ENSRNOP00000061906/1-1417 AILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAML ENSMUSP00000082971/1-1405 AILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAML ENSCPOP00000001011/1-1442 AILNQFAANAPVGMTMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAML ENSP00000385216/1-1441 AILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAML XP_004839504.1/1-1393 AILNQFAAAAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAML ******** ****:.************************************:******** ENSRNOP00000061906/1-1417 MRHQSFGNNIPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP ENSMUSP00000082971/1-1405 MRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP ENSCPOP00000001011/1-1442 MRQQSFGNNLPPSSGLPVQMGSPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP ENSP00000385216/1-1441 MRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP XP_004839504.1/1-1393 MRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANP **:******:***********.************************************** ENSRNOP00000061906/1-1417 EASLATRSSMVNRGMAGNMGGQFGTGISPQMQQNVFQYPGSGLVPQAEANFAPSLSPGSS ENSMUSP00000082971/1-1405 EASLATRSSMVNRGMAGNMGGQFGAGISPQMQQNVFQYPGPGLVPQGEATFAPSLSPGSS ENSCPOP00000001011/1-1442 EAPLATRSSMVSRGMAGTMGGQFGTGISPQMQQNVFQYPGSGMVPQSEANFAPSLSPGSS ENSP00000385216/1-1441 EASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSS XP_004839504.1/1-1393 EASLATRNSMVSRGMAGNMGGQFGTAINPQMQQNVFQYPGSGMVPQSEANFAPSLSPGSS **.**.*.***.***:*.:*****:.*.************.*:***.**.********** ENSRNOP00000061906/1-1417 MVPMPI-PPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNN ENSMUSP00000082971/1-1405 MVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNN ENSCPOP00000001011/1-1442 MVPMPIPPPQSSLLQQTPPTSGYQSPDMKAWQQGAMASNNVFSQAVQNQPTPAPPGVYNN ENSP00000385216/1-1441 MVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNN XP_004839504.1/1-1393 MVPMPIPPPQSSLLQQTPPSSGYQSPDMKAWQQGAMGSNNVFGQAVQNQPTPAQPGVYNN *****: ************:**************::..****.****.**:** ****** ENSRNOP00000061906/1-1417 MSITVSMAGGNANVQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSST ENSMUSP00000082971/1-1405 MSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSST ENSCPOP00000001011/1-1442 MSITVSMAGGSTDVQNMNPMMGQMQMGSLQMPGMNAVCPEQINDPALRHTGLYCNQLSST ENSP00000385216/1-1441 MSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSST XP_004839504.1/1-1393 MSITVSMAGGNTNVQNMNPMMGQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSST **********.:::*******.****.********:**.**:****************** ENSRNOP00000061906/1-1417 DLLKTEADGNQDKKTEEFFSVQVQQLQVFADVQCTVNLKGASKPTLVLAVLLQEKAIRTN ENSMUSP00000082971/1-1405 DLLKTDADGNQ------------------------------------------------- ENSCPOP00000001011/1-1442 DLLKTEADGTQ----------QVQQVQVFADVQCTVNLVGGD----------------PY ENSP00000385216/1-1441 DLLKTEADGTQ----------QVQQVQVFADVQCTVNLVGGD----------------PY XP_004839504.1/1-1393 DLLKTEADGTQ----------QVQQVQVFADVQCTVNLVGGD----------------PY *****:***.* ENSRNOP00000061906/1-1417 ADEEHGLKTSRKKPFPQVLPSASHRPWYKQLHKNSIYSETTGL ENSMUSP00000082971/1-1405 --------------------DKKTEEFFSVVTTD--------- ENSCPOP00000001011/1-1442 LNQPGPLGSQKPTPGPQT-PQVQQKSLLQQLLTE--------- ENSP00000385216/1-1441 LNQPGPLGTQKPTSGPQT-PQAQQKSLLQQLLTE--------- XP_004839504.1/1-1393 LNQPGPLGSQKPTPGPQT-PQAQQKSLLQQLLTE--------- . . . . : .: