CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000023812/1-888 MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG ENSRNOP00000020437/1-888 MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG ENSP00000449038/1-892 MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGG XP_004872817.1/1-892 MACLHETRTPSPSFGGFMSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGA ENSCPOP00000000871/1-892 MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTQCVLRDVVPLGGQGA *****************:*****************************************. ENSMUSP00000023812/1-888 GGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGF ENSRNOP00000020437/1-888 GGPSPSPGGEPPPEPFANSVLQLHEQDTGGPGGATGSPESRASRVRADEVRLQCQSGSGF ENSP00000449038/1-892 GGPSPSPGGEPPPEPFANSVLQLHEQDAGGPGGAAGSPESRASRVRADEVRLQCQSGSGF XP_004872817.1/1-892 GGPSPSPGGEPPPEPFANSVLQLHEQDAGGPGGATGSPESRASRVRADEVRLQCQSGSGF ENSCPOP00000000871/1-892 GGPSPSPGGEPPPEPFANSILQLHEQDAGGPGGATGSPESRASRVRADEVRLQCQSGSGF *******************:*******:******:************************* ENSMUSP00000023812/1-888 LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE ENSRNOP00000020437/1-888 LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE ENSP00000449038/1-892 LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE XP_004872817.1/1-892 LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE ENSCPOP00000000871/1-892 LEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFHGE ************************************************************ ENSMUSP00000023812/1-888 EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP ENSRNOP00000020437/1-888 EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP ENSP00000449038/1-892 EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP XP_004872817.1/1-892 EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP ENSCPOP00000000871/1-892 EVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRP ************************************************************ ENSMUSP00000023812/1-888 VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK ENSRNOP00000020437/1-888 VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK ENSP00000449038/1-892 VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK XP_004872817.1/1-892 VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK ENSCPOP00000000871/1-892 VTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTK ************************************************************ ENSMUSP00000023812/1-888 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL ENSRNOP00000020437/1-888 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL ENSP00000449038/1-892 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL XP_004872817.1/1-892 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL ENSCPOP00000000871/1-892 MSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSL ************************************************************ ENSMUSP00000023812/1-888 HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR ENSRNOP00000020437/1-888 HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR ENSP00000449038/1-892 HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR XP_004872817.1/1-892 HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR ENSCPOP00000000871/1-892 HLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWR ************************************************************ ENSMUSP00000023812/1-888 EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM ENSRNOP00000020437/1-888 EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM ENSP00000449038/1-892 EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM XP_004872817.1/1-892 EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM ENSCPOP00000000871/1-892 EEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANNLYMELNALM ************************************************************ ENSMUSP00000023812/1-888 LQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD ENSRNOP00000020437/1-888 LQLELKERELLRREQALERRCPGLLKSHTSRSLLHGNTMEKLIKKRNVPQKLSPHSKRPD ENSP00000449038/1-892 LQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD XP_004872817.1/1-892 LQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD ENSCPOP00000000871/1-892 LQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNVPQKLSPHSKRPD **************************.*.**.**************************** ENSMUSP00000023812/1-888 ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALP ENSRNOP00000020437/1-888 ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAALP ENSP00000449038/1-892 ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRTAVP XP_004872817.1/1-892 ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLPGLRAAVQ ENSCPOP00000000871/1-892 ILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKMRHRKASAKGSCGDLPGLRAAVP ************************************* ******************:*: ENSMUSP00000023812/1-888 PHEPGGLGSPGGLGVGPSAWDACPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATG ENSRNOP00000020437/1-888 PHEPGGLGSPGGLGVGPTAWDACPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGATG ENSP00000449038/1-892 PHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRGATG XP_004872817.1/1-892 PHEPGGPGSPGGLGMGPSAWEACPAALRGLHHDLLLRKMSSSSPDLLSAALGTRGRGAT- ENSCPOP00000000871/1-892 PHELGGPGSPGALGVGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGARGRGAT- *** ** ****.** **:**:***.***************************:****** ENSMUSP00000023812/1-888 GARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTAG ENSRNOP00000020437/1-888 GARDPGSPPPPQGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTTG ENSP00000449038/1-892 GAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSG XP_004872817.1/1-892 GAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGTGLPGTGREGTAG ENSCPOP00000000871/1-892 GAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGSGLLGTGREGTAG ** *******.:*********************************** ** *******:* ENSMUSP00000023812/1-888 RGGNRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQS ENSRNOP00000020437/1-888 RGGSRAGYQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELPPSQRWPQGPNMRQS ENSP00000449038/1-892 RGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQS XP_004872817.1/1-892 RGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQGLNMRQS ENSCPOP00000000871/1-892 RGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQGLNMRQS ***.*** *************************************..******. ***** ENSMUSP00000023812/1-888 LSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEV ENSRNOP00000020437/1-888 LSTFSSENPSDVEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDLPTSEV ENSP00000449038/1-892 LSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPPSEV XP_004872817.1/1-892 LSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDDRPDERSDDMCSQGSEIPLDPPASEV ENSCPOP00000000871/1-892 LSTFSSENPSDGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPASEV *********** **********************:******************* *.*** ENSMUSP00000023812/1-888 VPEREASSLPMQHQD----GQGP-NPEDSDCDSTELDNSNSIDALRPPASLPP ENSRNOP00000020437/1-888 VPERETSSLPMQHQD----DQGP-NPEDSDCDSTELDNSNSIDALRPPASLPP ENSP00000449038/1-892 IPGPEPSSLPIPHQELLR-ERGPPNSEDSDCDSTELDNSNSVDALRPPASLPP XP_004872817.1/1-892 VPEPEPSSLAISQQDLIRGEQGPLNSEDSDCDSTELDNSNSVDALRPPASPPP ENSCPOP00000000871/1-892 VPEPEPSSLAVPHQDLLRGEQGPPNSEDSDCDSTELDNSHSVDALRPPASLPP :* *.***.: :*: :** *.*************:*:******** **