CLUSTAL W(1.81) multiple sequence alignment XP_004875411.1/1-517 MSLFKARDWWSTVLGEKEEYDQGCLCLADVDNSENGQDKIIVGSFMGYLRIFNPRPVKTG ENSMUSP00000120927/1-885 MSLFKARDWWSTVLGEKEEFDQGCLCLADVDNSGNGHDKIIVGSFMGYLRIFSPHSVKAG ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 MSLFKARDWWSTILGDKEEFDQGCLCLANVDNSGNGQDKIIVGSFMGYLRIFSPHPAKTG ENSCPOP00000000840/1-870 MSLFKARDWWSTLLGEKEEFDQGCLCLADVDNSGSGQDKIIVGSFMGYLRIFNPHPVKTG XP_004875411.1/1-517 DGAQAEDLLLEVHLRDPILQVEVGKFVSGTEMLHLAVLHSRKLCVYFVSGTLGNVEHGNQ ENSMUSP00000120927/1-885 GGPQAEDLLLEVHLRDPVLQVEVGKFVSGTEMLHLAVLHSRKLCVYSVSGTLGNVEHGNQ ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 DGAQAEDLLLEVDLRDPVLQVEVGKFVSGTEMLHLAVLHSRKLCVYSVSGTLGNVEHGNQ ENSCPOP00000000840/1-870 DGAQAEDLLLEVHLRDPILQVEVGKFVSGTELLHLAVLHSRKLCVYFVSGTLGNVEHGNQ XP_004875411.1/1-517 YQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSVDGMLMLFEQESYAFGRFLPGSLL ENSMUSP00000120927/1-885 YQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSLDGMLMVFEQESYAFGRFLPGFLL ENSRNOP00000020481/1-450 ---------------------------GRDLICIQSMDGMLMVFEQESYAFGRFLPGSLL ENSP00000242067/1-887 CQMKLMYEHNLQRTACNMTYGSFGGVKGRDLICIQSMDGMLMVFEQESYAFGRFLPGFLL ENSCPOP00000000840/1-870 YQIRLMYEHHLQRTACNMTCGPFGGVKGRDLICIQSMDGMLMVFEQESYAFGRFLPGSLL *********:*****:************** ** XP_004875411.1/1-517 PGPLAYSSRTDSFITVSSCQQVESYKYQVLAFATDADKREETEQQKLGSGKRLVVDWTLN ENSMUSP00000120927/1-885 PGPLAYSPRTDSFITVSSCRQVESYKYQVLAFATDADKKQEMEQQKLGSGKRLVVDWTLN ENSRNOP00000020481/1-450 PGPLAYSPRTDSFITVSSCRQVESYKYQVLAFATDADKKQEMEQQKLGSGKRLVVDWTLN ENSP00000242067/1-887 PGPLAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQQKLGSGKRLVVDWTLN ENSCPOP00000000840/1-870 PGPLAYSSRTDSFITVSSCRQVESYKYQVLVFATDADKREETEQQKLGSGKRLVVDWTLN *******.*****:*****:**********.*******::* ****************** XP_004875411.1/1-517 IGEQALDICIVSFNQSTSSVFVLGERNFFCLKDNGQIRFMKKLDCSPSCFLPYCSVSEGT ENSMUSP00000120927/1-885 IGEQALDICIFPLNQSASSVFVLGERNFFCLKDNGQIRFMKKLGYNPSCFLPYCSVSEGT ENSRNOP00000020481/1-450 IGEQALDICIIPLNQSASSVFVLGERNFFCLKDNGQIRFMKKLDCSPSCFLPYCSVSEGT ENSP00000242067/1-887 IGEQALDICIVSFNQSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPYCSVSEGT ENSCPOP00000000840/1-870 IGEQALDICIVSFNQSTSSVFVLGERNFFCLKDNGQIRFMKKLDCSPSCFLPYCSVSEGT **********..:***:**************************. .************** XP_004875411.1/1-517 INTLIGNHNNMLHIYQDVTLKWAAQLPHIPVAVKVGSMHDLRGVIVTLSDDGHLQCSYLG ENSMUSP00000120927/1-885 INTLIGNHNHMLHIYQDVTLKWATQLPHVPVAVRVGCFHDLKGVIVTLSDDGHLQCSYLG ENSRNOP00000020481/1-450 INTLVGNHNHMLHVYQDVTLKWATQLPHVPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLG ENSP00000242067/1-887 INTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYLG ENSCPOP00000000840/1-870 INTLIGNHNSMLHIYQDVTLKWATQLPHIPVAVKVGSLHDLKGVIVTLSDDGHLQCSYLG ****:**** ***:*********:****:****:**.:***:****************** XP_004875411.1/1-517 TDPSLFQAPKVESRELNYEELDVELEELQKIIKDV-KAEGVWPMTEREDDLKVSAAVSPN ENSMUSP00000120927/1-885 TDPSLFQAPKVESRELNYDELDVELKELQKIIKDV-KLQGVWPLTEQEDDLKVSASVSST ENSRNOP00000020481/1-450 TDPSLFQAPKVESRELNYDELDVELKELQKIIKDV-KSQGVWPLTEQEDDLKVSAAVSSA ENSP00000242067/1-887 TDPSLFQAPNVQSRELNYDELDVEMKELQKIIKDVNKSQGVWPMTEREDDLNVSVVVSPN ENSCPOP00000000840/1-870 TDPSLFQAPKVESRELNYKELDAELKELQKIIKDV-KSQGVWPMTEREDDLRVFATVSPN *********:*:******.***.*::********* * :****:**:****.* . **. XP_004875411.1/1-517 FDSVSQATDADIGIDRVPSITVKVLYQG-----------YLEP--------MSSSFLTD- ENSMUSP00000120927/1-885 LDSVSQATNVEPGADSVPSITVKITLQNRVVLQKVKLSIYVQPPLQLTCDQFTFDFTVPD ENSRNOP00000020481/1-450 LDSVSQATNVETGADSVPSITVKITLQNQVVLQKVKLSVYVQPPLQLTCDQFTFDFVAPD ENSP00000242067/1-887 FDSVSQATDVEVGTDLVPSVTVKVTLQNRVILQKAKLSVYVQPPLELTCDQFTFEFMTPD ENSCPOP00000000840/1-870 FDSVSQATDADIGTDLVPSITVKVVLQSRLALQKVKLSVYVQPPLALTCDHFSFDFMAPE :*******:.: * * ***:***: *. *::* :: .* . XP_004875411.1/1-517 -------------------------------------------------------LPVDG ENSMUSP00000120927/1-885 MTSSVAFSVYLKRNYTPSELEGNAVVSYSRPTDRNPDGIPRVVQCKFRLPLKLICLPGQP ENSRNOP00000020481/1-450 MTSIVTFSVYLKKTYTPSELEGNAVVSYSRATGKHVSGIPRVIQCKFRLPLNLICLPGQP ENSP00000242067/1-887 LTRTVSFSVYLKRSYTPSELEGNAVVSYSRPTDRNPDGIPRVIQCKFRLPLKLICLPGQP ENSCPOP00000000840/1-870 TTREVAFSVYLKRSYTPSELEGNAVVSYFKPTDRNPDGIPRVIQCKFRLPLKLICLPGQP ** : XP_004875411.1/1-517 SRHVRQRVS-DTGKNTSA--------ACSREEE--------LLGGQQPSGTSAHVTHASG ENSMUSP00000120927/1-885 SKTASHKLTIDTNKSPVSLLGLFPDFANPSDDDQVNVMGFRLLGGARVTLLASRTSQRYR ENSRNOP00000020481/1-450 SKTASHKLTIDTNKSPVSLLGLFPDFANPSDDDQMNVMGFRLLGGSRVTLLASRTSRK-- ENSP00000242067/1-887 SKTASHKITIDTNKSPVSLLSLFPGFASQSDDDQVNVMGFHFLGGARITVLASKTSQRYR ENSCPOP00000000840/1-870 SKSASHKLTIDTNKSPVSLLSLFPGFSSQPDDDQVNVMGFCFLGGSRVTLLASKTSQRYR *: . :::: **.*.. : : ::: :*** : : :::.:: XP_004875411.1/1-517 VIA---PNLWSAE----------------------------------------------- ENSMUSP00000120927/1-885 IQSEQFEDLWLITNELILRLQEHFEKQGTKDFSCSFSGCVPLQEYFELIDHHFELRINGK ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 IQSEQFEDLWLITNELILRLQEYFEKQGVKDFACSFSGSIPLQEYFELIDHHFELRINGE ENSCPOP00000000840/1-870 IQSEQFEDLWLIINELILRLHEYFEKQGIKDFSCSFSGSMPLQEYFELIDHHFELRINGE XP_004875411.1/1-517 ------------------------------------------------------------ ENSMUSP00000120927/1-885 KLEELLSERAVQFRAIQRRLLTRFRDKTPAPLQHLDTLLDGTYKQVIALADAIEENQDRL ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 KLEELLSERAVQFRAIQRRLLARFKDKTPAPLQHLDTLLDGTYKQVIALADAVEENQGNL ENSCPOP00000000840/1-870 KLEELLSERAVQFRAIQRRLLTRFKDKTPAPLQHLDTLLDGTYKQVIALAEAVEENQANL XP_004875411.1/1-517 ------------------------------------------------------------ ENSMUSP00000120927/1-885 LQSFSGLKSATHLLILLIRLWQRLSADQTAILEAAFLPLQEDTQELGWEETVDAAIAYLL ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 FQSFTRLKSATHLVILLIALWQKLSADQVAILEAAFLPLQEDTQELGWEETVDAAISHLL ENSCPOP00000000840/1-870 FQAFARLKSATHLVILLIGLWQKLSADQVAILEAAFLPLQEDAQELGWEETVDAAVSHLL XP_004875411.1/1-517 ------------------------------------------------------------ ENSMUSP00000120927/1-885 KTCLSKSSKEQALNLSSQLNIPKDTSRLKKHITLLCDRLAKGGRLCVSTDAAAPQAMVVP ENSRNOP00000020481/1-450 ------------------------------------------------------------ ENSP00000242067/1-887 KTCLSKSSKEQALNLNSQLNIPKDTSQLKKHITLLCDRLSKGGRLCLSTDAAAPQTMVMP ENSCPOP00000000840/1-870 KTCLSKSSKERALNLSSHLDMPKDTSRLKKHITLLCDRLAKGGRLCLSADSAAPQTIIMP XP_004875411.1/1-517 ----------------------------------------------- ENSMUSP00000120927/1-885 GGCTPIPESDLEERSLD-DSTELFTNHKHLMTEPPMPEVSARQGVLE ENSRNOP00000020481/1-450 ----------------------------------------------- ENSP00000242067/1-887 GGCTTIPESDLEERSVEQDSTELFTNHRHLTAETPRPEVSPLQGVSE ENSCPOP00000000840/1-870 GGCTPIPESDLEERSAEQDSTEPFTNHRLLM----------------